#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P70166 uniprotkb:Q8NDF8 intact:EBI-8621413|ensembl:ENSMUSP00000095936|uniprotkb:Q8C5P9|intact:MINT-261117 intact:EBI-2803971|uniprotkb:Q9NW67|uniprotkb:Q9Y6C0|uniprotkb:B4DV38 psi-mi:cpeb1_mouse(display_long)|uniprotkb:Cpeb1(gene name)|psi-mi:Cpeb1(display_short)|uniprotkb:Cpeb(gene name synonym) psi-mi:papd5_human(display_long)|uniprotkb:"Non-canonical poly(A) RNA polymerase PAPD5"(gene name synonym)|uniprotkb:TUT3(gene name synonym)|uniprotkb:Terminal guanylyltransferase(gene name synonym)|uniprotkb:TENT4B(gene name)|psi-mi:TENT4B(display_short)|uniprotkb:GLD4(gene name synonym)|uniprotkb:PAP-associated domain-containing protein 5(gene name synonym)|uniprotkb:PAPD5(gene name synonym)|uniprotkb:TRF4-2(gene name synonym)|uniprotkb:Terminal uridylyltransferase 3(gene name synonym)|uniprotkb:Topoisomerase-related function protein 4-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Burns et al. (2011) pubmed:21478871|doi:10.1038/nature09908|imex:IM-16205 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15921331|imex:IM-16205-1|dip:DIP-187220E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025586(gene)|ensembl:ENSMUST00000098331(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072687"(meiotic spindle)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032292|interpro:IPR032296|interpro:IPR034819|interpro:IPR034977|interpro:IPR035979|interpro:IPR038446|refseq:NP_031781.1|refseq:NP_001239454.1|refseq:NP_001239455.1|dip:DIP-41380N refseq:NP_001035375.2|refseq:NP_001035374.2|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0043630"(ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070568"(guanylyltransferase activity)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR040136|interpro:IPR043519|dip:DIP-59183N psi-mi:"MI:0465"(dip) comment:mint|function:"Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with MASKIN is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses. Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation. Induces the assembly of stress granules in the absence of stress" - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:gWr51Ie7xVskFIJlCaQ8OWNxSwo10090 rogid:Dy+EsRClygf3oq2i8AdtST3ENS49606 rigid:w8sW8g1EC78qKxWFSqRpj/UEhGc false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)