#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P63284	uniprotkb:P63284	intact:EBI-546182|uniprotkb:P03815|ensemblbacteria:AAC75641|ensemblbacteria:BAA16476	intact:EBI-546182|uniprotkb:P03815|ensemblbacteria:AAC75641|ensemblbacteria:BAA16476	psi-mi:clpb_ecoli(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:htpM(gene name synonym)|uniprotkb:b2592(locus name)|uniprotkb:Heat shock protein F84.1(gene name synonym)|uniprotkb:JW2573(locus name)	psi-mi:clpb_ecoli(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:htpM(gene name synonym)|uniprotkb:b2592(locus name)|uniprotkb:Heat shock protein F84.1(gene name synonym)|uniprotkb:JW2573(locus name)	psi-mi:"MI:0071"(molecular sieving)	Miot et al. (2011)	pubmed:21474779|doi:10.1073/pnas.1102828108|imex:IM-21235	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15920393|imex:IM-21235-1|dip:DIP-64796E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC75641(transcript)|ensemblbacteria:b2592(gene)|ensemblbacteria:BAA16476(gene)|ensemblbacteria:BAA16476(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546|rcsb pdb:1JBK|rcsb pdb:1KHY|rcsb pdb:4CIU|rcsb pdb:4D2Q|rcsb pdb:4D2U|rcsb pdb:4D2X|rcsb pdb:5OFO|rcsb pdb:5OG1|rcsb pdb:6OAX|rcsb pdb:6OAY|rcsb pdb:6OG1|rcsb pdb:6OG2|rcsb pdb:6OG3|rcsb pdb:6QS6|rcsb pdb:6QS7|rcsb pdb:6QS8|refseq:NP_417083.1|refseq:WP_001235102.1|mint:P63284|dip:DIP-35844N	ensemblbacteria:AAC75641(transcript)|ensemblbacteria:b2592(gene)|ensemblbacteria:BAA16476(gene)|ensemblbacteria:BAA16476(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546|rcsb pdb:1JBK|rcsb pdb:1KHY|rcsb pdb:4CIU|rcsb pdb:4D2Q|rcsb pdb:4D2U|rcsb pdb:4D2X|rcsb pdb:5OFO|rcsb pdb:5OG1|rcsb pdb:6OAX|rcsb pdb:6OAY|rcsb pdb:6OG1|rcsb pdb:6OG2|rcsb pdb:6OG3|rcsb pdb:6QS6|rcsb pdb:6QS7|rcsb pdb:6QS8|refseq:NP_417083.1|refseq:WP_001235102.1|mint:P63284|dip:DIP-35844N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:TpZoKsWC20K1+V6Y0or7s4WiFRo83333	rogid:TpZoKsWC20K1+V6Y0or7s4WiFRo83333	rigid:n/JWQ9ezYMC/DTBeWrddf3yeRrQ	false	mutation decreasing interaction strength:212-212	mutation decreasing interaction strength:212-212	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63284	uniprotkb:P63284	intact:EBI-546182|uniprotkb:P03815|ensemblbacteria:AAC75641|ensemblbacteria:BAA16476	intact:EBI-546182|uniprotkb:P03815|ensemblbacteria:AAC75641|ensemblbacteria:BAA16476	psi-mi:clpb_ecoli(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:htpM(gene name synonym)|uniprotkb:b2592(locus name)|uniprotkb:Heat shock protein F84.1(gene name synonym)|uniprotkb:JW2573(locus name)	psi-mi:clpb_ecoli(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:htpM(gene name synonym)|uniprotkb:b2592(locus name)|uniprotkb:Heat shock protein F84.1(gene name synonym)|uniprotkb:JW2573(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Miot et al. (2011)	pubmed:21474779|doi:10.1073/pnas.1102828108|imex:IM-21235	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15920412|imex:IM-21235-2|dip:DIP-64796E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC75641(transcript)|ensemblbacteria:b2592(gene)|ensemblbacteria:BAA16476(gene)|ensemblbacteria:BAA16476(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546|rcsb pdb:1JBK|rcsb pdb:1KHY|rcsb pdb:4CIU|rcsb pdb:4D2Q|rcsb pdb:4D2U|rcsb pdb:4D2X|rcsb pdb:5OFO|rcsb pdb:5OG1|rcsb pdb:6OAX|rcsb pdb:6OAY|rcsb pdb:6OG1|rcsb pdb:6OG2|rcsb pdb:6OG3|rcsb pdb:6QS6|rcsb pdb:6QS7|rcsb pdb:6QS8|refseq:NP_417083.1|refseq:WP_001235102.1|mint:P63284|dip:DIP-35844N	ensemblbacteria:AAC75641(transcript)|ensemblbacteria:b2592(gene)|ensemblbacteria:BAA16476(gene)|ensemblbacteria:BAA16476(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546|rcsb pdb:1JBK|rcsb pdb:1KHY|rcsb pdb:4CIU|rcsb pdb:4D2Q|rcsb pdb:4D2U|rcsb pdb:4D2X|rcsb pdb:5OFO|rcsb pdb:5OG1|rcsb pdb:6OAX|rcsb pdb:6OAY|rcsb pdb:6OG1|rcsb pdb:6OG2|rcsb pdb:6OG3|rcsb pdb:6QS6|rcsb pdb:6QS7|rcsb pdb:6QS8|refseq:NP_417083.1|refseq:WP_001235102.1|mint:P63284|dip:DIP-35844N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:TpZoKsWC20K1+V6Y0or7s4WiFRo83333	rogid:TpZoKsWC20K1+V6Y0or7s4WiFRo83333	rigid:i7gMTkzH1V0dCuZWootomNkMMJw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P31539	uniprotkb:P31539	intact:EBI-8050|uniprotkb:D6VXX8|ensemblfungi:YLL026W	intact:EBI-8050|uniprotkb:D6VXX8|ensemblfungi:YLL026W	psi-mi:hs104_yeast(display_long)|uniprotkb:HSP104(gene name)|psi-mi:HSP104(display_short)|uniprotkb:YLL026W(locus name)|uniprotkb:L0948(orf name)|uniprotkb:Protein aggregation-remodeling factor HSP104(gene name synonym)	psi-mi:hs104_yeast(display_long)|uniprotkb:HSP104(gene name)|psi-mi:HSP104(display_short)|uniprotkb:YLL026W(locus name)|uniprotkb:L0948(orf name)|uniprotkb:Protein aggregation-remodeling factor HSP104(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Miot et al. (2011)	pubmed:21474779|doi:10.1073/pnas.1102828108|imex:IM-21235	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15920429|imex:IM-21235-3|dip:DIP-2811E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003949|refseq:NP_013074.1|mint:P31539|dip:DIP-2252N|ensemblfungi:YLL026W(gene)|ensemblfungi:YLL026W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0043531"(ADP binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070370"(cellular heat acclimation)|go:"GO:0070414"(trehalose metabolism in response to heat stress)|go:"GO:0072380"(TRC complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546|rcsb pdb:5KNE|rcsb pdb:5U2U|rcsb pdb:5VJH|rcsb pdb:5VY8|rcsb pdb:5VY9|rcsb pdb:5VYA|rcsb pdb:5WBW|rcsb pdb:6AHF|rcsb pdb:6AMN|rcsb pdb:6N8T|rcsb pdb:6N8V|rcsb pdb:6N8Z	sgd:S000003949|refseq:NP_013074.1|mint:P31539|dip:DIP-2252N|ensemblfungi:YLL026W(gene)|ensemblfungi:YLL026W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0043531"(ADP binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070370"(cellular heat acclimation)|go:"GO:0070414"(trehalose metabolism in response to heat stress)|go:"GO:0072380"(TRC complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546|rcsb pdb:5KNE|rcsb pdb:5U2U|rcsb pdb:5VJH|rcsb pdb:5VY8|rcsb pdb:5VY9|rcsb pdb:5VYA|rcsb pdb:5WBW|rcsb pdb:6AHF|rcsb pdb:6AMN|rcsb pdb:6N8T|rcsb pdb:6N8V|rcsb pdb:6N8Z	psi-mi:"MI:0465"(dip)	crc64:4AD0E7E3AF98E318	crc64:4AD0E7E3AF98E318	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:rMl56qonOOODJUyLVkkWwUq8Cj4559292	rogid:rMl56qonOOODJUyLVkkWwUq8Cj4559292	rigid:wMXm8zk2LHCLvBmxuHhNf1SdTTo	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P03069	uniprotkb:P03069	intact:EBI-7450|uniprotkb:P03068|uniprotkb:Q70D88|uniprotkb:Q70D91|uniprotkb:Q70D96|uniprotkb:Q70D99|uniprotkb:Q70DA0|uniprotkb:Q96UT3|uniprotkb:D3DLN9|ensemblfungi:YEL009C	intact:EBI-7450|uniprotkb:P03068|uniprotkb:Q70D88|uniprotkb:Q70D91|uniprotkb:Q70D96|uniprotkb:Q70D99|uniprotkb:Q70DA0|uniprotkb:Q96UT3|uniprotkb:D3DLN9|ensemblfungi:YEL009C	psi-mi:gcn4_yeast(display_long)|uniprotkb:ARG9(gene name synonym)|uniprotkb:GCN4(gene name)|psi-mi:GCN4(display_short)|uniprotkb:AAS3(gene name synonym)|uniprotkb:Amino acid biosynthesis regulatory protein(gene name synonym)|uniprotkb:AAS101(gene name synonym)|uniprotkb:General control protein GCN4(gene name synonym)|uniprotkb:YEL009C(locus name)	psi-mi:gcn4_yeast(display_long)|uniprotkb:ARG9(gene name synonym)|uniprotkb:GCN4(gene name)|psi-mi:GCN4(display_short)|uniprotkb:AAS3(gene name synonym)|uniprotkb:Amino acid biosynthesis regulatory protein(gene name synonym)|uniprotkb:AAS101(gene name synonym)|uniprotkb:General control protein GCN4(gene name synonym)|uniprotkb:YEL009C(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Miot et al. (2011)	pubmed:21474779|doi:10.1073/pnas.1102828108|imex:IM-21235	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15920445|imex:IM-21235-4|dip:DIP-57036E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000735|refseq:NP_010907.3|mint:P03069|dip:DIP-591N|ensemblfungi:YEL009C(gene)|ensemblfungi:YEL009C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001080"(nitrogen catabolite activation of transcription from RNA polymerase II promoter)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061412"(positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:1CE9|rcsb pdb:1DGC|rcsb pdb:1ENV|rcsb pdb:1FAV|rcsb pdb:1FMH|rcsb pdb:1GCL|rcsb pdb:1GCM|rcsb pdb:1GK6|rcsb pdb:1GZL|rcsb pdb:1IHQ|rcsb pdb:1IJ0|rcsb pdb:1IJ1|rcsb pdb:1IJ2|rcsb pdb:1IJ3|rcsb pdb:1KQL|rcsb pdb:1LD4|rcsb pdb:1LLM|rcsb pdb:1NKN|rcsb pdb:1PIQ|rcsb pdb:1RB4|rcsb pdb:1RB5|rcsb pdb:1RB6|rcsb pdb:1SWI|rcsb pdb:1TMZ|rcsb pdb:1UNT|rcsb pdb:1UNU|rcsb pdb:1UNV|rcsb pdb:1UNW|rcsb pdb:1UNX|rcsb pdb:1UNY|rcsb pdb:1UNZ|rcsb pdb:1UO0|rcsb pdb:1UO1|rcsb pdb:1UO2|rcsb pdb:1UO3|rcsb pdb:1UO4|rcsb pdb:1UO5|rcsb pdb:1W5G|rcsb pdb:1W5H|rcsb pdb:1W5I|rcsb pdb:1W5J|rcsb pdb:1W5K|rcsb pdb:1W5L|rcsb pdb:1YSA|rcsb pdb:1ZII|rcsb pdb:1ZIJ|rcsb pdb:1ZIK|rcsb pdb:1ZIL|rcsb pdb:1ZIM|rcsb pdb:1ZTA|rcsb pdb:2AHP|rcsb pdb:2B1F|rcsb pdb:2B22|rcsb pdb:2BNI|rcsb pdb:2CCE|rcsb pdb:2CCF|rcsb pdb:2CCN|rcsb pdb:2D3E|rcsb pdb:2DGC|rcsb pdb:2EFR|rcsb pdb:2EFS|rcsb pdb:2G9J|rcsb pdb:2HY6|rcsb pdb:2IPZ|rcsb pdb:2K8X|rcsb pdb:2LPB|rcsb pdb:2N9B|rcsb pdb:2NRN|rcsb pdb:2O7H|rcsb pdb:2OVN|rcsb pdb:2VKY|rcsb pdb:2VNL|rcsb pdb:2WG5|rcsb pdb:2WG6|rcsb pdb:2WPY|rcsb pdb:2WPZ|rcsb pdb:2WQ0|rcsb pdb:2WQ1|rcsb pdb:2WQ2|rcsb pdb:2WQ3|rcsb pdb:2YNY|rcsb pdb:2YNZ|rcsb pdb:2YO0|rcsb pdb:2YO1|rcsb pdb:2YO2|rcsb pdb:2YO3|rcsb pdb:2Z5H|rcsb pdb:2Z5I|rcsb pdb:2ZTA|rcsb pdb:3AZD|rcsb pdb:3BAS|rcsb pdb:3BAT|rcsb pdb:3CK4|rcsb pdb:3CRP|rcsb pdb:3G9R|rcsb pdb:3GJP|rcsb pdb:3I1G|rcsb pdb:3I5C|rcsb pdb:3K7Z|rcsb pdb:3M48|rcsb pdb:3P8M|rcsb pdb:3ZMF|rcsb pdb:4C46|rcsb pdb:4DMD|rcsb pdb:4G2K|rcsb pdb:4HU5|rcsb pdb:4HU6|rcsb pdb:4NIZ|rcsb pdb:4NJ0|rcsb pdb:4NJ1|rcsb pdb:4NJ2|rcsb pdb:4OWI|rcsb pdb:4TL1|rcsb pdb:5APP|rcsb pdb:5APQ|rcsb pdb:5APS|rcsb pdb:5APT|rcsb pdb:5APU|rcsb pdb:5APV|rcsb pdb:5APW|rcsb pdb:5APX|rcsb pdb:5APY|rcsb pdb:5APZ|rcsb pdb:5IEW|rcsb pdb:5IIR|rcsb pdb:5IIV|rcsb pdb:5KHT|rcsb pdb:6E52|rcsb pdb:6E95|rcsb pdb:6H9M|rcsb pdb:6HN4|rcsb pdb:6HN5|rcsb pdb:6O2E|rcsb pdb:6O2F|rcsb pdb:6PSA|rcsb pdb:6UT2|rcsb pdb:6VWG|rcsb pdb:6VWH|rcsb pdb:6VWI|rcsb pdb:6VWJ|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450341	sgd:S000000735|refseq:NP_010907.3|mint:P03069|dip:DIP-591N|ensemblfungi:YEL009C(gene)|ensemblfungi:YEL009C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001080"(nitrogen catabolite activation of transcription from RNA polymerase II promoter)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061412"(positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:1CE9|rcsb pdb:1DGC|rcsb pdb:1ENV|rcsb pdb:1FAV|rcsb pdb:1FMH|rcsb pdb:1GCL|rcsb pdb:1GCM|rcsb pdb:1GK6|rcsb pdb:1GZL|rcsb pdb:1IHQ|rcsb pdb:1IJ0|rcsb pdb:1IJ1|rcsb pdb:1IJ2|rcsb pdb:1IJ3|rcsb pdb:1KQL|rcsb pdb:1LD4|rcsb pdb:1LLM|rcsb pdb:1NKN|rcsb pdb:1PIQ|rcsb pdb:1RB4|rcsb pdb:1RB5|rcsb pdb:1RB6|rcsb pdb:1SWI|rcsb pdb:1TMZ|rcsb pdb:1UNT|rcsb pdb:1UNU|rcsb pdb:1UNV|rcsb pdb:1UNW|rcsb pdb:1UNX|rcsb pdb:1UNY|rcsb pdb:1UNZ|rcsb pdb:1UO0|rcsb pdb:1UO1|rcsb pdb:1UO2|rcsb pdb:1UO3|rcsb pdb:1UO4|rcsb pdb:1UO5|rcsb pdb:1W5G|rcsb pdb:1W5H|rcsb pdb:1W5I|rcsb pdb:1W5J|rcsb pdb:1W5K|rcsb pdb:1W5L|rcsb pdb:1YSA|rcsb pdb:1ZII|rcsb pdb:1ZIJ|rcsb pdb:1ZIK|rcsb pdb:1ZIL|rcsb pdb:1ZIM|rcsb pdb:1ZTA|rcsb pdb:2AHP|rcsb pdb:2B1F|rcsb pdb:2B22|rcsb pdb:2BNI|rcsb pdb:2CCE|rcsb pdb:2CCF|rcsb pdb:2CCN|rcsb pdb:2D3E|rcsb pdb:2DGC|rcsb pdb:2EFR|rcsb pdb:2EFS|rcsb pdb:2G9J|rcsb pdb:2HY6|rcsb pdb:2IPZ|rcsb pdb:2K8X|rcsb pdb:2LPB|rcsb pdb:2N9B|rcsb pdb:2NRN|rcsb pdb:2O7H|rcsb pdb:2OVN|rcsb pdb:2VKY|rcsb pdb:2VNL|rcsb pdb:2WG5|rcsb pdb:2WG6|rcsb pdb:2WPY|rcsb pdb:2WPZ|rcsb pdb:2WQ0|rcsb pdb:2WQ1|rcsb pdb:2WQ2|rcsb pdb:2WQ3|rcsb pdb:2YNY|rcsb pdb:2YNZ|rcsb pdb:2YO0|rcsb pdb:2YO1|rcsb pdb:2YO2|rcsb pdb:2YO3|rcsb pdb:2Z5H|rcsb pdb:2Z5I|rcsb pdb:2ZTA|rcsb pdb:3AZD|rcsb pdb:3BAS|rcsb pdb:3BAT|rcsb pdb:3CK4|rcsb pdb:3CRP|rcsb pdb:3G9R|rcsb pdb:3GJP|rcsb pdb:3I1G|rcsb pdb:3I5C|rcsb pdb:3K7Z|rcsb pdb:3M48|rcsb pdb:3P8M|rcsb pdb:3ZMF|rcsb pdb:4C46|rcsb pdb:4DMD|rcsb pdb:4G2K|rcsb pdb:4HU5|rcsb pdb:4HU6|rcsb pdb:4NIZ|rcsb pdb:4NJ0|rcsb pdb:4NJ1|rcsb pdb:4NJ2|rcsb pdb:4OWI|rcsb pdb:4TL1|rcsb pdb:5APP|rcsb pdb:5APQ|rcsb pdb:5APS|rcsb pdb:5APT|rcsb pdb:5APU|rcsb pdb:5APV|rcsb pdb:5APW|rcsb pdb:5APX|rcsb pdb:5APY|rcsb pdb:5APZ|rcsb pdb:5IEW|rcsb pdb:5IIR|rcsb pdb:5IIV|rcsb pdb:5KHT|rcsb pdb:6E52|rcsb pdb:6E95|rcsb pdb:6H9M|rcsb pdb:6HN4|rcsb pdb:6HN5|rcsb pdb:6O2E|rcsb pdb:6O2F|rcsb pdb:6PSA|rcsb pdb:6UT2|rcsb pdb:6VWG|rcsb pdb:6VWH|rcsb pdb:6VWI|rcsb pdb:6VWJ|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450341	psi-mi:"MI:0465"(dip)	crc64:2ED1B8E35D509578	crc64:2ED1B8E35D509578	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:MFj9JcYccWKTayvnuaN95djsHd0559292	rogid:MFj9JcYccWKTayvnuaN95djsHd0559292	rigid:q9aALwC1bPcZROqvbqKmvdK/TwY	false	sufficient binding region:253-274	sufficient binding region:253-274	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63284	uniprotkb:P0A6Y8	intact:EBI-546182|uniprotkb:P03815|ensemblbacteria:AAC75641|ensemblbacteria:BAA16476	intact:EBI-542092|uniprotkb:P04475|ensemblbacteria:AAC73125|ensemblbacteria:BAB96589	psi-mi:clpb_ecoli(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:htpM(gene name synonym)|uniprotkb:b2592(locus name)|uniprotkb:Heat shock protein F84.1(gene name synonym)|uniprotkb:JW2573(locus name)	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Miot et al. (2011)	pubmed:21474779|doi:10.1073/pnas.1102828108|imex:IM-21235	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15920466|imex:IM-21235-5|dip:DIP-190196E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC75641(transcript)|ensemblbacteria:b2592(gene)|ensemblbacteria:BAA16476(gene)|ensemblbacteria:BAA16476(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546|rcsb pdb:1JBK|rcsb pdb:1KHY|rcsb pdb:4CIU|rcsb pdb:4D2Q|rcsb pdb:4D2U|rcsb pdb:4D2X|rcsb pdb:5OFO|rcsb pdb:5OG1|rcsb pdb:6OAX|rcsb pdb:6OAY|rcsb pdb:6OG1|rcsb pdb:6OG2|rcsb pdb:6OG3|rcsb pdb:6QS6|rcsb pdb:6QS7|rcsb pdb:6QS8|refseq:NP_417083.1|refseq:WP_001235102.1|mint:P63284|dip:DIP-35844N	refseq:NP_414555.1|ensemblbacteria:AAC73125(transcript)|ensemblbacteria:b0014(gene)|ensemblbacteria:BAB96589(gene)|ensemblbacteria:BAB96589(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016989"(sigma factor antagonist activity)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0043531"(ADP binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:4EZQ|refseq:WP_000516135.1|mint:P0A6Y8|dip:DIP-35751N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:TpZoKsWC20K1+V6Y0or7s4WiFRo83333	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rigid:oaD5K90Kt8Nq0O2YHEIx82UYPZk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)