#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P49590 uniprotkb:P49590 intact:EBI-3909030|uniprotkb:B4DDY8|intact:EBI-10988212|ensembl:ENSP00000230771|ensembl:ENSP00000494296 intact:EBI-3909030|uniprotkb:B4DDY8|intact:EBI-10988212|ensembl:ENSP00000230771|ensembl:ENSP00000494296 psi-mi:syhm_human(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:HARS2(gene name)|psi-mi:HARS2(display_short)|uniprotkb:HARSL(gene name synonym)|uniprotkb:HARSR(gene name synonym)|uniprotkb:HO3(gene name synonym)|uniprotkb:Histidine--tRNA ligase-like(gene name synonym) psi-mi:syhm_human(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:HARS2(gene name)|psi-mi:HARS2(display_short)|uniprotkb:HARSL(gene name synonym)|uniprotkb:HARSR(gene name synonym)|uniprotkb:HO3(gene name synonym)|uniprotkb:Histidine--tRNA ligase-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pierce et al. (2011) pubmed:21464306|doi:10.1073/pnas.1103471108|imex:IM-17544 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15920256|imex:IM-17544-1|dip:DIP-188866E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036340.1|refseq:NP_001265660.1|refseq:NP_001265661.1|ensembl:ENSG00000112855(gene)|ensembl:ENST00000230771(transcript)|ensembl:ENST00000645749(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR033656|interpro:IPR036621|interpro:IPR041715|reactome:R-HSA-379726|go:"GO:0006412"(translation)|dip:DIP-59626N refseq:NP_036340.1|refseq:NP_001265660.1|refseq:NP_001265661.1|ensembl:ENSG00000112855(gene)|ensembl:ENST00000230771(transcript)|ensembl:ENST00000645749(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR033656|interpro:IPR036621|interpro:IPR041715|reactome:R-HSA-379726|go:"GO:0006412"(translation)|dip:DIP-59626N psi-mi:"MI:0465"(dip) - - dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:pp4g+OJKxW3va88iXtfIAnGXMKw9606 rogid:pp4g+OJKxW3va88iXtfIAnGXMKw9606 rigid:RYcNQpA8hcEzYFBRkYM4SAfSaGs false flag tag:c-c|necessary binding region:200-211|mutation increasing interaction strength:368-368 myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)