#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:28304"	uniprotkb:P15127	intact:EBI-1379423	intact:EBI-7472166|intact:MINT-1348005|uniprotkb:P97681	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:insr_rat(display_long)|uniprotkb:Insr(gene name)|psi-mi:Insr(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	mint:P15127|rgd:2917|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001889"(liver development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005009"(insulin-activated receptor activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0005901"(caveola)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008544"(epidermis development)|go:"GO:0008584"(male gonad development)|go:"GO:0009725"(response to hormone)|go:"GO:0009749"(response to glucose)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010033"(response to organic substance)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0010560"(positive regulation of glycoprotein biosynthetic process)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030238"(male sex determination)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031405"(lipoic acid binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032094"(response to food)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033280"(response to vitamin D)|go:"GO:0033574"(response to testosterone)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042594"(response to starvation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043423"(3-phosphoinositide-dependent protein kinase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043559"(insulin binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:0060417"(yolk)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0097421"(liver regeneration)|go:"GO:1902438"("response to vanadate(3-)")|go:"GO:1904638"(response to resveratrol)|go:"GO:1990402"(embryonic liver development)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000194"(regulation of female gonad development)|go:"GO:2000252"(negative regulation of feeding behavior)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016246(Insulin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036941|interpro:IPR040969|rcsb pdb:4XST|rcsb pdb:5TQ1|reactome:R-RNO-6811558|reactome:R-RNO-74713|reactome:R-RNO-74749|reactome:R-RNO-74751|reactome:R-RNO-74752|reactome:R-RNO-77387|go:"GO:0051384"(response to glucocorticoid)|dip:DIP-42209N	-	-	comment:mint|comment:homomint|function:This receptor binds insulin and has a tyrosine-protein kinase activity	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:ldt21SpdR80CvCb99s38/rfnIZs10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P16310	intact:EBI-1379423	intact:EBI-7383787|uniprotkb:Q64236|intact:MINT-4588405|uniprotkb:Q80XW9|ensembl:ENSRNOP00000044119	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:ghr_rat(display_long)|uniprotkb:Ghr(gene name)|psi-mi:Ghr(display_short)|uniprotkb:Somatotropin receptor(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_008758976.1|rgd:2687|refseq:NP_058790.1|ensembl:ENSRNOG00000015654(gene)|ensembl:ENSRNOT00000046951(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004903"(growth hormone receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009725"(response to hormone)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019838"(growth factor binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0032094"(response to food)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0034097"(response to cytokine)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043278"(response to morphine)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070195"(growth hormone receptor complex)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR025871|interpro:IPR036116|reactome:R-RNO-1170546|reactome:R-RNO-982772|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|dip:DIP-63N	-	-	function:Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway|comment:mint|function:"The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling"	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:dazvxWCK8/PnACZxoC5RRUKmIIY10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P14740	intact:EBI-1379423	intact:EBI-7276458|intact:MINT-4655516	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:dpp4_rat(display_long)|uniprotkb:Dpp4(gene name)|psi-mi:Dpp4(display_short)|uniprotkb:Cd26(gene name synonym)|uniprotkb:Dipeptidyl peptidase IV(gene name synonym)|uniprotkb:T-cell activation antigen CD26(gene name synonym)|uniprotkb:GP110 glycoprotein(gene name synonym)|uniprotkb:Bile canaliculus domain-specific membrane glycoprotein(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	mint:P14740|rgd:2515|refseq:NP_036921.1|interpro:IPR040522|go:"GO:0001618"(virus receptor activity)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002020"(protease binding)|go:"GO:0002337"(B-1a B cell differentiation)|go:"GO:0002709"(regulation of T cell mediated immunity)|go:"GO:0002717"(positive regulation of natural killer cell mediated immunity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008239"(dipeptidyl-peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010716"(negative regulation of extracellular matrix disassembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0033632"(regulation of cell-cell adhesion mediated by integrin)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0042110"(T cell activation)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0051234"(establishment of localization)|go:"GO:0090024"(negative regulation of neutrophil chemotaxis)|rcsb pdb:2GBC|rcsb pdb:2GBF|rcsb pdb:2GBG|rcsb pdb:2GBI|rcsb pdb:2I3Z|rcsb pdb:2OAE|rcsb pdb:4FFV|rcsb pdb:4FFW|rcsb pdb:5VTA|reactome:R-RNO-381771|reactome:R-RNO-400511|interpro:IPR029058|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002469(Peptidase S9B, dipeptidylpeptidase IV N-terminal)|interpro:IPR002471(Peptidase S9, serine active site)	-	-	comment:mint|function:Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:m8Q93+awYHQ/IxEcbxuS/I/VBxc10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P05371	intact:EBI-1379423	intact:EBI-7618723|intact:MINT-4586114	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:clus_rat(display_long)|uniprotkb:Clu(gene name)|psi-mi:Clu(display_short)|uniprotkb:Sulfated glycoprotein 2(gene name synonym)|uniprotkb:Dimeric acid glycoprotein(gene name synonym)|uniprotkb:Testosterone repressed prostate message 2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR000753(Clusterin-like)|mint:P05371|interpro:IPR033986|interpro:IPR016014(Clusterin, N-terminal)|rgd:3907|interpro:IPR016015(Clusterin, C-terminal)|interpro:IPR016016(Clusterin)|refseq:NP_444180.2|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002434"(immune complex clearance)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009611"(response to wounding)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0017038"(protein import)|go:"GO:0030426"(growth cone)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032286"(central nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0035864"(response to potassium ion)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042583"(chromaffin granule)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0099020"(perinuclear endoplasmic reticulum lumen)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902847"(regulation of neuronal signal transduction)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1905892"(negative regulation of cellular response to thapsigargin)|go:"GO:1905895"(negative regulation of cellular response to tunicamycin)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|reactome:R-RNO-114608|reactome:R-RNO-166665|reactome:R-RNO-6803157|reactome:R-RNO-977606	-	-	function:Not yet clear. It is known to be expressed in a variety of tissues and it seems to be able to bind to cells, membranes and hydrophobic proteins. It has been associated with programmed cell death|comment:mint	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:x6HdtxJsow7AbujjffoBUB2fxac10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P14668	intact:EBI-1379423	intact:EBI-8589497|intact:MINT-4996466	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:anxa5_rat(display_long)|uniprotkb:Anxa5(gene name)|psi-mi:Anxa5(display_short)|uniprotkb:Anx5(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0043025"(neuronal cell body)|go:"GO:1902721"(negative regulation of prolactin secretion)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0051592"(response to calcium ion)|go:"GO:0071284"(cellular response to lead ion)|go:"GO:0072563"(endothelial microparticle)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:0097211"(cellular response to gonadotropin-releasing hormone)|go:"GO:1901317"(regulation of flagellated sperm motility)|rcsb pdb:1A8A|rcsb pdb:1A8B|rcsb pdb:1BC0|rcsb pdb:1BC1|rcsb pdb:1BC3|rcsb pdb:1BCW|rcsb pdb:1BCY|rcsb pdb:1BCZ|rcsb pdb:1G5N|rcsb pdb:1N41|rcsb pdb:1N42|rcsb pdb:1N44|rcsb pdb:2H0K|rcsb pdb:2H0L|rcsb pdb:2H0M|rcsb pdb:2IE6|rcsb pdb:2IE7|rcsb pdb:2RAN|reactome:R-RNO-114608|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010033"(response to organic substance)|go:"GO:0014704"(intercalated disc)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0030018"(Z disc)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0005634"(nucleus)|go:"GO:0042995"(cell projection)|interpro:IPR001464(Annexin)|interpro:IPR018252|rgd:2120|interpro:IPR018502|interpro:IPR002392(Annexin, type V)|refseq:NP_037264.1|mint:P14668|interpro:IPR037104	-	-	comment:mint|function:This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:lF/1juTWLRKTc7qgr9c52PEOozE10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P04157	intact:EBI-1379423	intact:EBI-7186263|ensembl:ENSRNOP00000063859|intact:UNK-6021416	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:ptprc_rat(display_long)|uniprotkb:Leukocyte common antigen(gene name synonym)|uniprotkb:Ptprc(gene name)|psi-mi:Ptprc(display_short)|uniprotkb:T200(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_006249972.1|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0044855"(plasma membrane raft distribution)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048539"(bone marrow development)|go:"GO:0048864"(stem cell development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050857"(positive regulation of antigen receptor-mediated signaling pathway)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061097"(regulation of protein tyrosine kinase activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071944"(cell periphery)|go:"GO:0098857"(membrane microdomain)|go:"GO:1903615"(positive regulation of protein tyrosine phosphatase activity)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000473"(positive regulation of hematopoietic stem cell migration)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016335(Leukocyte common antigen)|interpro:IPR024739|interpro:IPR029021|interpro:IPR036116|rcsb pdb:5FN8|reactome:R-RNO-202427|reactome:R-RNO-416700|reactome:R-RNO-6798695|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|ensembl:ENSRNOG00000000655(gene)|go:"GO:0005887"(integral component of plasma membrane)|ensembl:ENSRNOT00000064785(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0002923"(regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032059"(bleb)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0010332"(response to gamma radiation)|refseq:NP_001103358.1|refseq:NP_001103360.1|refseq:NP_612516.2|refseq:NP_001103359.1|rgd:3451|refseq:NP_001103357.1	-	-	comment:mint|function:Required for T-cell activation through the antigen receptor. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits an dephosphorylates SKAP1 and FYN	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:2uCaAJvK7daopMKhyuNKMm9Rrks10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P04785	intact:EBI-1379423	intact:EBI-915861|uniprotkb:P13700|ensembl:ENSRNOP00000051841	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:pdia1_rat(display_long)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:P4hb(gene name)|psi-mi:P4hb(display_short)|uniprotkb:Pdia1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_037130.2|rgd:3244|ensembl:ENSRNOG00000036689(gene)|ensembl:ENSRNOT00000054958(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P04785|reactome:R-RNO-1650814|reactome:R-RNO-3299685|reactome:R-RNO-381426|reactome:R-RNO-5358346|reactome:R-RNO-8866423|reactome:R-RNO-8957275|reactome:R-RNO-8963888|reactome:R-RNO-9020591|reactome:R-RNO-9020933	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:nXaUDIKzWIRQ95lFxT0hB0T9enQ10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q5EBA8	intact:EBI-1379423	intact:EBI-15348927|ensembl:ENSRNOP00000013698	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:pcft_rat(display_long)|uniprotkb:Slc46a1(gene name)|psi-mi:Slc46a1(display_short)|uniprotkb:Hcp1(gene name synonym)|uniprotkb:Pcft(gene name synonym)|uniprotkb:Heme carrier protein 1(gene name synonym)|uniprotkb:PCFT/HCP1(gene name synonym)|uniprotkb:Solute carrier family 46 member 1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-RNO-9707616|reactome:R-RNO-917937|ensembl:ENSRNOG00000010291(gene)|ensembl:ENSRNOT00000013698(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008517"(folic acid transmembrane transporter activity)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015350"(methotrexate transmembrane transporter activity)|go:"GO:0015884"(folic acid transport)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0051958"(methotrexate transport)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904447"(folate import across plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|reactome:R-RNO-196757|refseq:NP_001013991.1|refseq:XP_006247001.1|rgd:1309472	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:OMsnbXOSEftwh2sOpOz1kp59dpk10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q6AXS5	intact:EBI-1379423	intact:EBI-931289|uniprotkb:Q8VHU3	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:pairb_rat(display_long)|uniprotkb:Serbp1(gene name)|psi-mi:Serbp1(display_short)|uniprotkb:Pairbp1(gene name synonym)|uniprotkb:Rda288(gene name synonym)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:RDA288(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_006236678.1|interpro:IPR032381|rgd:619907|refseq:NP_659554.1|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR039764|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0048471"(perinuclear region of cytoplasm)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:or19Hte0zmMnvmOBo2v3EKOrFMo10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q6P6T5	intact:EBI-1379423	intact:EBI-15348891|ensembl:ENSRNOP00000024674|ensembl:ENSRNOP00000068691|uniprotkb:Q9Z303	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:ocln_rat(display_long)|uniprotkb:Ocln(gene name)|psi-mi:Ocln(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000018297(gene)|ensembl:ENSRNOT00000024674(transcript)|ensembl:ENSRNOT00000084667(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0120193"(tight junction organization)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|reactome:R-RNO-351906|go:"GO:0045216"(cell-cell junction organization)|refseq:NP_112619.2|refseq:XP_006231915.1|refseq:XP_006231916.1|refseq:XP_006231917.1|rgd:620089|dip:DIP-48891N	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:aPlKXgZTH+pHHf+Pb5XTApmGags10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P26435	intact:EBI-1379423	intact:EBI-15348868|ensembl:ENSRNOP00000007825|uniprotkb:Q5BK99	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:ntcp_rat(display_long)|uniprotkb:Slc10a1(gene name)|psi-mi:Slc10a1(display_short)|uniprotkb:Ntcp(gene name synonym)|uniprotkb:"Na(+)/bile acid cotransporter"(gene name synonym)|uniprotkb:"Na(+)/taurocholate transport protein"(gene name synonym)|uniprotkb:Sodium/taurocholate cotransporting polypeptide(gene name synonym)|uniprotkb:Solute carrier family 10 member 1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000005794(gene)|ensembl:ENSRNOT00000007825(transcript)|go:"GO:0008508"("bile acid:sodium symporter activity")|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0035690"|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0045471"(response to ethanol)|go:"GO:0120188"(regulation of bile acid secretion)|go:"GO:1904486"(response to 17alpha-ethynylestradiol)|interpro:IPR002657("Bile acid:sodium symporter")|interpro:IPR004710(Bile acid transporter)|interpro:IPR030208|interpro:IPR038770|reactome:R-RNO-159418|refseq:NP_058743.1|rgd:3681	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:3fiMAwB2iYjmy/oY72b0fXHCuD810116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q8CGU6	intact:EBI-1379423	intact:EBI-919483|uniprotkb:Q8CH12|ensembl:ENSRNOP00000008150	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:nica_rat(display_long)|uniprotkb:Ncstn(gene name)|psi-mi:Ncstn(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:631418|refseq:NP_777353.1|refseq:XP_008767955.1|ensembl:ENSRNOG00000005355(gene)|ensembl:ENSRNOT00000008150(transcript)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0007611"(learning or memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008233"(peptidase activity)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0021549"(cerebellum development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030534"(adult behavior)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042500"(aspartic endopeptidase activity, intramembrane cleaving)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0042983"(amyloid precursor protein biosynthetic process)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0045202"(synapse)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0070997"(neuron death)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1990926"(short-term synaptic potentiation)|interpro:IPR008710(Nicastrin)|interpro:IPR041084|reactome:R-RNO-1251985|reactome:R-RNO-193692|reactome:R-RNO-205043|reactome:R-RNO-3928665|reactome:R-RNO-6798695|reactome:R-RNO-9013507|reactome:R-RNO-9017802	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:i7mLB/dG+pTidsJNUywhbvAzjDs10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:O88269	intact:EBI-1379423	intact:EBI-15348831|ensembl:ENSRNOP00000051412	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:mrp6_rat(display_long)|uniprotkb:Abcc6(gene name)|psi-mi:Abcc6(display_short)|uniprotkb:Mlp1(gene name synonym)|uniprotkb:Mrp6(gene name synonym)|uniprotkb:MRP-like protein 1(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 6(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005292("Multi drug resistance-associated protein (MRP)")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030239|interpro:IPR036640|reactome:R-RNO-382556|interpro:IPR003439(ABC transporter-like)|ensembl:ENSRNOG00000028781(gene)|ensembl:ENSRNOT00000042115(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015867"(ATP transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030504"(inorganic diphosphate transmembrane transporter activity)|go:"GO:0030505"(inorganic diphosphate transport)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0005654"(nucleoplasm)|refseq:NP_112275.1|rgd:620268	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:gT18MpkaiKY+HM69u05A1nQVrT410116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q8K1P8	intact:EBI-1379423	intact:EBI-15348813	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:mot8_rat(display_long)|uniprotkb:SLC16A2(gene name)|psi-mi:SLC16A2(display_short)|uniprotkb:Mct8(gene name synonym)|uniprotkb:Solute carrier family 16 member 2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009914"(hormone transport)|go:"GO:0015293"(symporter activity)|go:"GO:0015349"(thyroid hormone transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042403"(thyroid hormone metabolic process)|go:"GO:0070327"(thyroid hormone transport)|go:"GO:0070460"(thyroid-stimulating hormone secretion)|go:"GO:0089718"(amino acid import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:0015171"(amino acid transmembrane transporter activity)|reactome:R-RNO-879518|refseq:NP_671749.1|interpro:IPR030761|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|rgd:628608|interpro:IPR036259	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:DVevYnEM7PidrTOQKDak/5xHohI10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P53987	intact:EBI-1379423	intact:EBI-15348773|ensembl:ENSRNOP00000027234	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:mot1_rat(display_long)|uniprotkb:Slc16a1(gene name)|psi-mi:Slc16a1(display_short)|uniprotkb:Mct1(gene name synonym)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000019996(gene)|ensembl:ENSRNOT00000027234(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0032094"(response to food)|go:"GO:0035873"(lactate transmembrane transport)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:1905039"(carboxylic acid transmembrane transport)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR030757|interpro:IPR036259|reactome:R-RNO-210991|reactome:R-RNO-433692|reactome:R-RNO-70268|go:"GO:0051780"(behavioral response to nutrient)|refseq:NP_036848.1|refseq:XP_017446125.1|rgd:3690	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:eLc24JvS7TDfgVC9/CfiZJDy7aA10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q10739	intact:EBI-1379423	intact:EBI-15348698|ensembl:ENSRNOP00000065434|uniprotkb:Q6IN06	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:mmp14_rat(display_long)|uniprotkb:Mmp14(gene name)|psi-mi:Mmp14(display_short)|uniprotkb:Mtmmp(gene name synonym)|uniprotkb:Membrane-type matrix metalloproteinase 1(gene name synonym)|uniprotkb:Membrane-type-1 matrix metalloproteinase(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0031012"(extracellular matrix)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031638"(zymogen activation)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0044354"(macropinosome)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060322"(head development)|go:"GO:0060348"(bone development)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1990834"(response to odorant)|interpro:IPR000585(Hemopexin)|ensembl:ENSRNOG00000010947(gene)|ensembl:ENSRNOT00000075610(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001666"(response to hypoxia)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR021805|interpro:IPR024079|interpro:IPR033739|interpro:IPR036365|interpro:IPR036366|interpro:IPR036375|reactome:R-RNO-1442490|reactome:R-RNO-1474228|reactome:R-RNO-1592389|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009725"(response to hormone)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|refseq:NP_112318.1|rgd:620198	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:MR5Sku2V5YP0XoZBzqgDJBNg+GE10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P30904	intact:EBI-1379423	intact:EBI-917216|ensembl:ENSRNOP00000008608|ensembl:ENSRNOP00000074316	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:mif_rat(display_long)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glutathione-binding 13 kDa protein(gene name synonym)|uniprotkb:Mif(gene name)|psi-mi:Mif(display_short)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_008772068.1|rgd:621163|refseq:NP_112313.1|refseq:XP_017457271.1|ensembl:ENSRNOG00000006589(gene)|ensembl:ENSRNOG00000056076(gene)|ensembl:ENSRNOT00000008608(transcript)|ensembl:ENSRNOT00000077564(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0002020"(protease binding)|go:"GO:0002035"(brain renin-angiotensin system)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0009408"(response to heat)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009725"(response to hormone)|go:"GO:0009986"(cell surface)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032572"(response to menaquinone)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033197"(response to vitamin E)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042756"(drinking behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061078"(positive regulation of prostaglandin secretion involved in immune response)|go:"GO:0061081"(positive regulation of myeloid leukocyte cytokine production involved in immune response)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090238"(positive regulation of arachidonic acid secretion)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P30904|rcsb pdb:1FIM|reactome:R-RNO-202733|reactome:R-RNO-6798695	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:IKr3IOgugXY3QiwggmHWGn9D8d810116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P97523	intact:EBI-1379423	intact:EBI-15348614|uniprotkb:P97579|uniprotkb:Q63119|uniprotkb:Q63964	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:met_rat(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0030425"(dendrite)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007595"(lactation)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|reactome:R-RNO-6806942|reactome:R-RNO-6807004|reactome:R-RNO-6811558|reactome:R-RNO-8851805|reactome:R-RNO-8851907|interpro:IPR031148|reactome:R-RNO-1257604|reactome:R-RNO-8865999|reactome:R-RNO-416550|reactome:R-RNO-5673001|reactome:R-RNO-8874081|reactome:R-RNO-8875513|reactome:R-RNO-8875555|reactome:R-RNO-8875656|reactome:R-RNO-8875791|refseq:NP_113705.1|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR016201(Plexin-like fold)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|rgd:3082|interpro:IPR036352	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:t1KYyzo4ANRoU4zb9PKAJKAFXpc10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q08201	intact:EBI-1379423	intact:EBI-929988|uniprotkb:Q78E07	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:mdr3_rat(display_long)|uniprotkb:Pgp3(gene name synonym)|uniprotkb:Pgy2(gene name synonym)|uniprotkb:Abcb4(gene name)|psi-mi:Abcb4(display_short)|uniprotkb:Mdr2(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 4(gene name synonym)|uniprotkb:P-glycoprotein 2(gene name synonym)|uniprotkb:P-glycoprotein 3(gene name synonym)|uniprotkb:Multidrug resistance protein 2(gene name synonym)|uniprotkb:Multidrug resistance protein 3(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:620248|refseq:NP_036822.1|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR030275|interpro:IPR036640|interpro:IPR039421|reactome:R-RNO-382556|go:"GO:0000139"(Golgi membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032782"(bile acid secretion)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0090554"(phosphatidylcholine floppase activity)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0099038"(ceramide floppase activity)|go:"GO:1901557"(response to fenofibrate)|go:"GO:1903413"(cellular response to bile acid)|go:"GO:2001140"(positive regulation of phospholipid transport)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:4wNwfyHY7IIHYFR9bHpFIqYT8xE10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P43245	intact:EBI-1379423	intact:EBI-15348563|uniprotkb:Q63426|uniprotkb:Q63427	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:mdr1_rat(display_long)|uniprotkb:Abcb1(gene name)|psi-mi:Abcb1(display_short)|uniprotkb:Mdr1(gene name synonym)|uniprotkb:Mdr1b(gene name synonym)|uniprotkb:Pgy1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 1(gene name synonym)|uniprotkb:P-glycoprotein 1(gene name synonym)|uniprotkb:Multidrug resistance protein 1(gene name synonym)|uniprotkb:Phospholipid transporter ABCB1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:1903416"(response to glycoside)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001890"(placenta development)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007420"(brain development)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0014045"(establishment of endothelial blood-brain barrier)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033595"(response to genistein)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0061843"(Sertoli cell barrier remodeling)|go:"GO:0071217"(cellular response to external biotic stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090554"(phosphatidylcholine floppase activity)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0097327"(response to antineoplastic agent)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0099038"(ceramide floppase activity)|go:"GO:0099040"(ceramide translocation)|go:"GO:0140328"(floppase activity)|go:"GO:0007595"(lactation)|reactome:R-RNO-382556|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR027417|rgd:3318|interpro:IPR036640|interpro:IPR039421	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:Mb18J8+BCbUTh2y6fZ2Gj/+BIgw10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P08661	intact:EBI-1379423	intact:EBI-15348511|ensembl:ENSRNOP00000064876	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:mbl2_rat(display_long)|uniprotkb:Mbl2(gene name)|psi-mi:Mbl2(display_short)|uniprotkb:Mannan-binding protein(gene name synonym)|uniprotkb:Ra-reactive factor polysaccharide-binding component p28A(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005615"(extracellular space)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR001304(C-type lectin)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016186(C-type lectin-like)|go:"GO:0005581"(collagen trimer)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033990|interpro:IPR037570|ensembl:ENSRNOG00000050305(gene)|ensembl:ENSRNOT00000072188(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005537"(mannose binding)|rcsb pdb:1BV4|rcsb pdb:1KZA|rcsb pdb:1KZB|rcsb pdb:1KZC|rcsb pdb:1KZD|rcsb pdb:1KZE|rcsb pdb:1RDI|rcsb pdb:1RDJ|rcsb pdb:1RDK|rcsb pdb:1RDL|rcsb pdb:1RDM|rcsb pdb:1RDN|rcsb pdb:1RDO|reactome:R-RNO-166662|reactome:R-RNO-166663|refseq:NP_073195.2|refseq:XP_003749135.1|refseq:XP_003749136.1|refseq:XP_006231311.1|refseq:XP_006231312.1|rgd:67380	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:gtfzR+/Bb0nUWW5dLWioiD0kGdI10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:O88923	intact:EBI-1379423	intact:EBI-15348469|uniprotkb:O88918|uniprotkb:O88919|uniprotkb:O88920|uniprotkb:O88921|uniprotkb:O88922|uniprotkb:Q9Z174	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:agrl2_rat(display_long)|uniprotkb:Adgrl2(gene name)|psi-mi:Adgrl2(display_short)|uniprotkb:Cirl2(gene name synonym)|uniprotkb:Cl2(gene name synonym)|uniprotkb:Lphn2(gene name synonym)|uniprotkb:Calcium-independent alpha-latrotoxin receptor 2(gene name synonym)|uniprotkb:Latrophilin-2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043005"(neuron projection)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0009617"(response to bacterium)|interpro:IPR036445|refseq:NP_001177404.2|refseq:NP_001289137.1|refseq:NP_001289138.1|refseq:NP_001289139.1|refseq:NP_001289140.1|refseq:NP_001289141.1|refseq:NP_599235.3|interpro:IPR032471|interpro:IPR017981|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR017983|interpro:IPR000203(GPS)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR043159|rgd:620835|interpro:IPR031240	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:0mNUwf1rD0ocG+TqVkWbVmMeAlI10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P07867	intact:EBI-1379423	intact:EBI-9206530	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:lipc_rat(display_long)|uniprotkb:Lipc(gene name)|psi-mi:Lipc(display_short)|uniprotkb:Lipase member C(gene name synonym)|uniprotkb:Lysophospholipase(gene name synonym)|uniprotkb:Phospholipase A1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-RNO-8963889|reactome:R-RNO-8964026|rgd:3009|interpro:IPR000734(Lipase)|interpro:IPR002333(Hepatic lipase)|interpro:IPR013818(Lipase, N-terminal)|interpro:IPR016272(Lipoprotein lipase, LIPH)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR033906|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035478"(chylomicron binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043200"(response to amino acid)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001889"(liver development)|go:"GO:0004465"(lipoprotein lipase activity)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006658"(phosphatidylserine metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009725"(response to hormone)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010034"(response to acetate)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016298"(lipase activity)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0008201"(heparin binding)|go:"GO:0046337"(phosphatidylethanolamine metabolic process)|go:"GO:0046461"(neutral lipid catabolic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046473"(phosphatidic acid metabolic process)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0046688"(response to copper ion)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0048589"(developmental growth)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070542"(response to fatty acid)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|interpro:IPR029058|interpro:IPR036392	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:obrhrldmjc8L9jVT8v25eYlRJoM10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P97840	intact:EBI-1379423	intact:EBI-15348378|uniprotkb:O08588|uniprotkb:O35866	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:leg9_rat(display_long)|uniprotkb:Lgals9(gene name)|psi-mi:Lgals9(display_short)|uniprotkb:36 kDa beta-galactoside-binding lectin(gene name synonym)|uniprotkb:Urate transporter/channel(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048030"(disaccharide binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0070241"(positive regulation of activated T cell autonomous cell death)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000406"(positive regulation of T cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000563"(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000670"(positive regulation of dendritic cell apoptotic process)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001190"(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032815"(negative regulation of natural killer cell activation)|go:"GO:0032823"(regulation of natural killer cell differentiation)|go:"GO:0032834"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0043322"(negative regulation of natural killer cell degranulation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0019899"(enzyme binding)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002519"(natural killer cell tolerance induction)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006811"(ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007565"(female pregnancy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016936"(galactoside binding)|interpro:IPR044156|refseq:NP_037109.1|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR001079(Galectin, galactose-binding lectin)|rgd:3005	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:JLzAdEGLpOg98bk8bNrJ0aT2UXU10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:O70535	intact:EBI-1379423	intact:EBI-15348443	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:lifr_rat(display_long)|uniprotkb:Lifr(gene name)|psi-mi:Lifr(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034097"(response to cytokine)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0043235"(receptor complex)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040817|interpro:IPR040901|reactome:R-RNO-6788467|refseq:NP_112310.1|interpro:IPR003961(Fibronectin, type III)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR013783(Immunoglobulin-like fold)|rgd:621431|interpro:IPR036116	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:tQdreCfB908lB54pL3bx+1MD18010116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q9Z2H4	intact:EBI-1379423	intact:EBI-15348397|ensembl:ENSRNOP00000007681|uniprotkb:G3V6R1	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:lgr4_rat(display_long)|uniprotkb:Lgr4(gene name)|psi-mi:Lgr4(display_short)|uniprotkb:Gpr48(gene name synonym)|uniprotkb:G-protein coupled receptor 48(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000005715(gene)|ensembl:ENSRNOT00000007681(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001942"(hair follicle development)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008201"(heparin binding)|go:"GO:0016500"(protein-hormone receptor activity)|go:"GO:0030282"(bone mineralization)|go:"GO:0030539"(male genitalia development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046849"(bone remodeling)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048565"(digestive tract development)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0061290"(canonical Wnt signaling pathway involved in metanephric kidney development)|go:"GO:0072202"(cell differentiation involved in metanephros development)|go:"GO:0072224"(metanephric glomerulus development)|go:"GO:0072282"(metanephric nephron tubule morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR032675|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|refseq:NP_775450.1|rgd:628615	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:SmflHJwkT92j5QxCPVj6Zi/0wWk10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P35952	intact:EBI-1379423	intact:EBI-15348337	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:ldlr_rat(display_long)|uniprotkb:Ldlr(gene name)|psi-mi:Ldlr(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0045471"(response to ethanol)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061771"(response to caloric restriction)|go:"GO:0061889"(negative regulation of astrocyte activation)|go:"GO:0070508"(cholesterol import)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090118"(receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0097443"(sorting endosome)|go:"GO:0002020"(protease binding)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007568"(aging)|go:"GO:0007616"(long-term memory)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009725"(response to hormone)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010899"(regulation of phosphatidylcholine catabolic process)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0030229"(very-low-density lipoprotein particle receptor activity)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032355"(response to estradiol)|go:"GO:0033762"(response to glucagon)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034381"(plasma lipoprotein particle clearance)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0045177"(apical part of cell)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905167"(positive regulation of lysosomal protein catabolic process)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1990666"(PCSK9-LDLR complex)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8964026|reactome:R-RNO-8964038|refseq:NP_786938.1|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR018097|interpro:IPR009030(Growth factor, receptor)|interpro:IPR023415|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|rgd:2998|interpro:IPR036055	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:3WBnhe62ywfi+XKdJOH9gJpff5410116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P97629	intact:EBI-1379423	intact:EBI-918098|uniprotkb:Q11009	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:lcap_rat(display_long)|uniprotkb:Oxytocinase(gene name synonym)|uniprotkb:Insulin-regulated membrane aminopeptidase(gene name synonym)|uniprotkb:Insulin-responsive aminopeptidase(gene name synonym)|uniprotkb:Placental leucine aminopeptidase(gene name synonym)|uniprotkb:Vesicle protein of 165 kDa(gene name synonym)|uniprotkb:GP160(gene name synonym)|uniprotkb:Lnpep(gene name)|psi-mi:Lnpep(display_short)|uniprotkb:Irap(gene name synonym)|uniprotkb:Otase(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR034016|interpro:IPR034017|interpro:IPR027268|interpro:IPR024571|rgd:621752|refseq:NP_001106874.1|refseq:NP_598258.1|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|refseq:XP_008757040.1|refseq:XP_017443357.1|interpro:IPR042097|reactome:R-RNO-1236977|reactome:R-RNO-983168|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0009986"(cell surface)|go:"GO:0010813"(neuropeptide catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043229"(intracellular organelle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:3zV4e3lXuMwdpmkemkRXQZrDugc10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P08934	intact:EBI-1379423	intact:EBI-10758758|uniprotkb:P08933	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:kng1_rat(display_long)|uniprotkb:Kng1(gene name)|psi-mi:Kng1(display_short)|uniprotkb:Kng(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2980|refseq:NP_036873.1|interpro:IPR002395(HMW kininogen)|interpro:IPR027358|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR018073|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002542"(Factor XII activation)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042311"(vasodilation)|go:"GO:0043204"(perikaryon)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050672"(negative regulation of lymphocyte proliferation)|go:"GO:0052548"(regulation of endopeptidase activity)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:+n9kTIHhef+yleRfZ04M/jIwghQ10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q5XIE8	intact:EBI-1379423	intact:EBI-15348306|ensembl:ENSRNOP00000023037	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q63416	intact:EBI-1379423	intact:EBI-15348287|ensembl:ENSRNOP00000023984	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:itih3_rat(display_long)|uniprotkb:Itih3(gene name)|psi-mi:Itih3(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010600(Inter-alpha-trypsin inhibitor heavy chain, C-terminal)|ensembl:ENSRNOG00000017689(gene)|ensembl:ENSRNOT00000023984(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030212"(hyaluronan metabolic process)|interpro:IPR036465|mint:Q63416|reactome:R-RNO-114608|interpro:IPR013694(Vault protein inter-alpha-trypsin)|refseq:NP_059047.1|rgd:620633	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:FYOFGuKPLOm1smHocQOD0RN7Qy810116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P18614	intact:EBI-1379423	intact:EBI-848806|ensembl:ENSRNOP00000074337	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:ita1_rat(display_long)|uniprotkb:Laminin and collagen receptor(gene name synonym)|uniprotkb:VLA-1(gene name synonym)|uniprotkb:CD49 antigen-like family member A(gene name synonym)|uniprotkb:Itga1(gene name)|psi-mi:Itga1(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2923|refseq:NP_112256.1|ensembl:ENSRNOG00000053550(gene)|ensembl:ENSRNOT00000086114(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042311"(vasodilation)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045123"(cellular extravasation)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|rcsb pdb:1CK4|rcsb pdb:1MHP|rcsb pdb:2B2X|reactome:R-RNO-216083|reactome:R-RNO-445355	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:csCQnkUlNZJfTdqqJBqH9eICFQk10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q6AYF9	intact:EBI-1379423	intact:EBI-15348255|ensembl:ENSRNOP00000030295	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:iigp5_rat(display_long)|uniprotkb:Irgc(gene name)|psi-mi:Irgc(display_short)|uniprotkb:Iigp5(gene name synonym)|uniprotkb:Irgc1(gene name synonym)|uniprotkb:Immunity-related GTPase cinema 1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOT00000030900(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0035458"(cellular response to interferon-beta)|interpro:IPR007743(Interferon-inducible GTPase)|interpro:IPR027417|interpro:IPR030385|ensembl:ENSRNOG00000024257(gene)|refseq:NP_001014038.1|refseq:XP_006228487.1|refseq:XP_006228488.1|refseq:XP_006228489.1|refseq:XP_008757149.1|rgd:1311107	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:/dCCILZoQtgfslivWcsBpYpxwaI10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P12336	intact:EBI-1379423	intact:EBI-15348107|uniprotkb:Q6LE98	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:gtr2_rat(display_long)|uniprotkb:Slc2a2(gene name)|psi-mi:Slc2a2(display_short)|uniprotkb:Glut2(gene name synonym)|uniprotkb:Glucose transporter type 2, liver(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0009749"(response to glucose)|go:"GO:0009758"(carbohydrate utilization)|go:"GO:0015755"(fructose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0070837"(dehydroascorbic acid transport)|go:"GO:1904659"(glucose transmembrane transport)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005353"(fructose transmembrane transporter activity)|reactome:R-RNO-189200|reactome:R-RNO-422356|reactome:R-RNO-8981373|interpro:IPR002440("Glucose transporter, type 2 (GLUT2)")|interpro:IPR020846|interpro:IPR005828(General substrate transporter)|interpro:IPR003663(Sugar transporter)|interpro:IPR005829(Sugar transporter, conserved site)|rgd:3705|interpro:IPR036259	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:1S5hRarI1Lwxn+29uHFU7FCGR9M10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P06866	intact:EBI-1379423	intact:EBI-15348208|uniprotkb:Q5EBB4|uniprotkb:Q7TP23	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:hpt_rat(display_long)|uniprotkb:Hp(gene name)|psi-mi:Hp(display_short)|uniprotkb:Liver regeneration-related protein LRRG173(gene name synonym)|uniprotkb:Ba1-647(orf name)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0001666"(response to hypoxia)|go:"GO:0001889"(liver development)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006953"(acute-phase response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0009408"(response to heat)|go:"GO:0009617"(response to bacterium)|go:"GO:0010033"(response to organic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033590"(response to cobalamin)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042594"(response to starvation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060416"(response to growth hormone)|go:"GO:0072562"(blood microparticle)|go:"GO:2000296"(negative regulation of hydrogen peroxide catabolic process)|go:"GO:0031638"(zymogen activation)|reactome:R-RNO-2168880|reactome:R-RNO-6798695|refseq:NP_036714.2|interpro:IPR008292(Haptoglobin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|rgd:2825|interpro:IPR035976|interpro:IPR043504	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:jahVVGrFaYqgFWl3yJ/oRTGLmV010116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:O35799	intact:EBI-1379423	intact:EBI-15348141|ensembl:ENSRNOP00000022881|uniprotkb:O35175	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:hfe_rat(display_long)|uniprotkb:Hfe(gene name)|psi-mi:Hfe(display_short)|uniprotkb:RT1-CAFE(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000016967(gene)|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1990357"(terminal web)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990641"(response to iron ion starvation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2001186"(negative regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031092|interpro:IPR036179|interpro:IPR037055|reactome:R-RNO-917977|go:"GO:0002626"(negative regulation of T cell antigen processing and presentation)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|ensembl:ENSRNOT00000022881(transcript)|go:"GO:0006953"(acute-phase response)|go:"GO:0007565"(female pregnancy)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0010106"(cellular response to iron ion starvation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042446"(hormone biosynthetic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060586"(multicellular organismal iron ion homeostasis)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0097421"(liver regeneration)|go:"GO:0098711"(iron ion import across plasma membrane)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904283"(negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:1904434"(positive regulation of ferrous iron binding)|go:"GO:0032092"(positive regulation of protein binding)|refseq:NP_445753.1|rgd:2793	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:st0Z7ZCyLKl1UI4j67ByH3QSrgs10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P31392	intact:EBI-1379423	intact:EBI-15348088|uniprotkb:Q64166	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:gp182_rat(display_long)|uniprotkb:Gpr182(gene name)|psi-mi:Gpr182(display_short)|uniprotkb:Admr(gene name synonym)|uniprotkb:G10D(gene name synonym)|uniprotkb:NOW(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0001605"(adrenomedullin receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001350(G10D orphan receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rgd:61903	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:WLfvrMZJDEkwwyyIo26j95Id5pY10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q68FP1	intact:EBI-1379423	intact:EBI-6096401|ensembl:ENSRNOP00000025857	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:gels_rat(display_long)|uniprotkb:Gsn(gene name)|psi-mi:Gsn(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1303089|refseq:NP_001004080.1|refseq:XP_006234102.1|ensembl:ENSRNOG00000018991(gene)|ensembl:ENSRNOT00000025857(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043209"(myelin sheath)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051593"(response to folic acid)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:Q68FP1|reactome:R-RNO-264870|reactome:R-RNO-6798695|go:"GO:0045471"(response to ethanol)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:VEJohA79kwmQ8WB+zZ5DO5Wjw1g10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P23377	intact:EBI-1379423	intact:EBI-15348045	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:furin_rat(display_long)|uniprotkb:Furin(gene name)|psi-mi:Furin(display_short)|uniprotkb:Fur(gene name synonym)|uniprotkb:Pcsk3(gene name synonym)|uniprotkb:Dibasic-processing enzyme(gene name synonym)|uniprotkb:Paired basic amino acid residue-cleaving enzyme(gene name synonym)|uniprotkb:Prohormone convertase 3(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0007568"(aging)|go:"GO:0008233"(peptidase activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0019058"(viral life cycle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031638"(zymogen activation)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0032940"(secretion by cell)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0090472"(dibasic protein processing)|go:"GO:1901394"(positive regulation of transforming growth factor beta1 activation)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002020"(protease binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0032902"(nerve growth factor production)|reactome:R-RNO-1592389|reactome:R-RNO-186797|reactome:R-RNO-2173789|reactome:R-RNO-1566948|reactome:R-RNO-159782|reactome:R-RNO-167060|reactome:R-RNO-8963889|interpro:IPR038466|refseq:NP_062204.1|interpro:IPR006212(Furin-like repeat)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR034182|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR023827|interpro:IPR022398|interpro:IPR023828|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR032815|rgd:3274|interpro:IPR036852	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:Xy6JymGqphUh9JSU8D2DiVGf5X010116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P04937	intact:EBI-1379423	intact:EBI-6127274|uniprotkb:Q6LDX9	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:finc_rat(display_long)|uniprotkb:Fn1(gene name)|psi-mi:Fn1(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	mint:P04937|rgd:2624|interpro:IPR000083(Fibronectin, type I)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0001775"(cell activation)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010039"(response to iron ion)|go:"GO:0010193"(response to ozone)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904646"(cellular response to amyloid-beta)|reactome:R-RNO-114608|reactome:R-RNO-1474228|reactome:R-RNO-1474244|reactome:R-RNO-1566977|reactome:R-RNO-202733|reactome:R-RNO-2129379|reactome:R-RNO-216083|reactome:R-RNO-3000170|reactome:R-RNO-3000171|reactome:R-RNO-3000178|reactome:R-RNO-354192|reactome:R-RNO-354194|reactome:R-RNO-372708|reactome:R-RNO-381426|reactome:R-RNO-5674135|reactome:R-RNO-8874081|reactome:R-RNO-8957275	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:eN6XoJTeRD0TcgGI43GcJY4zzXk10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P02680	intact:EBI-1379423	intact:EBI-5746951|uniprotkb:Q68FY3	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:fibg_rat(display_long)|uniprotkb:Fgg(gene name)|psi-mi:Fgg(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-RNO-114608|reactome:R-RNO-140875|reactome:R-RNO-216083|interpro:IPR037581|reactome:R-RNO-354192|reactome:R-RNO-354194|reactome:R-RNO-372708|reactome:R-RNO-5674135|rgd:2613|refseq:NP_036691.2|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR020837|refseq:XP_006232587.1|interpro:IPR036056|reactome:R-RNO-381426|reactome:R-RNO-8957275|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009306"(protein secretion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0036345"(platelet maturation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:CsN9NToE+VFaDt9W3oGSUHSQ7QQ10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:M0RBP3	intact:EBI-1379423	intact:EBI-15347927|ensembl:ENSRNOP00000066987	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:m0rbp3_rat(display_long)|uniprotkb:Nxpe1(gene name)|psi-mi:Nxpe1(display_short)|uniprotkb:RGD1566243(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOT00000072518(transcript)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026845|ensembl:ENSRNOG00000027730(gene)|refseq:XP_006243080.1|refseq:XP_006243081.1|refseq:XP_017451331.1|rgd:1566243	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:Y2zZlMjt2dCyBpZ/d/KAhiz6Fz810116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P14480	intact:EBI-1379423	intact:EBI-1187259|uniprotkb:Q5I0P7|uniprotkb:Q7TME5|ensembl:ENSRNOP00000009813	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:fibb_rat(display_long)|uniprotkb:Liver regeneration-related protein LRRG036/LRRG043/LRRG189(gene name synonym)|uniprotkb:Fgb(gene name)|psi-mi:Fgb(display_short)|uniprotkb:Ab1-181(orf name)|uniprotkb:Ab1-216(orf name)|uniprotkb:Ac1-581(orf name)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2604|refseq:NP_064456.2|ensembl:ENSRNOG00000007092(gene)|ensembl:ENSRNOT00000009813(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0034622"|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|reactome:R-RNO-114608|reactome:R-RNO-140875|reactome:R-RNO-216083|reactome:R-RNO-354192|reactome:R-RNO-354194|reactome:R-RNO-372708|reactome:R-RNO-5674135|go:"GO:0070527"(platelet aggregation)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:594ZUCBmPRLU8b9uGPrEK3hcG5I10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P06399	intact:EBI-1379423	intact:EBI-15347989	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:fiba_rat(display_long)|uniprotkb:Fga(gene name)|psi-mi:Fga(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060416"(response to growth hormone)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072377"(blood coagulation, common pathway)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0072562"(blood microparticle)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:0097421"(liver regeneration)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990643"(cellular response to granulocyte colony-stimulating factor)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0006953"(acute-phase response)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0033595"(response to genistein)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0043278"(response to morphine)|go:"GO:0044468"(envenomation resulting in modulation of blood coagulation in another organism)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0005737"(cytoplasm)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|reactome:R-RNO-114608|reactome:R-RNO-140875|reactome:R-RNO-216083|reactome:R-RNO-354192|reactome:R-RNO-354194|reactome:R-RNO-372708|reactome:R-RNO-381426|reactome:R-RNO-5674135|reactome:R-RNO-8957275|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR021996|interpro:IPR020837|interpro:IPR037579|rgd:2603|interpro:IPR036056	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:x/aj31KdIh3CrLUAKwYfqfbEsbg10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:O88182	intact:EBI-1379423	intact:EBI-15347969	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:fgf18_rat(display_long)|uniprotkb:Fgf18(gene name)|psi-mi:Fgf18(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002063"(chondrocyte development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005111"(type 2 fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000546"(positive regulation of endothelial cell chemotaxis to fibroblast growth factor)|refseq:NP_062072.1|interpro:IPR028289|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|rgd:2608|reactome:R-RNO-5654700|reactome:R-RNO-5654704|reactome:R-RNO-5654706|reactome:R-RNO-5654710|reactome:R-RNO-5654712|reactome:R-RNO-5654719|reactome:R-RNO-5654720|reactome:R-RNO-5654727|reactome:R-RNO-5654732|reactome:R-RNO-109704|reactome:R-RNO-1257604|reactome:R-RNO-190322|reactome:R-RNO-190371|reactome:R-RNO-190372|reactome:R-RNO-190375|reactome:R-RNO-5654221|reactome:R-RNO-5654227|reactome:R-RNO-5654228|reactome:R-RNO-5654695|reactome:R-RNO-5654699|reactome:R-RNO-5654733|reactome:R-RNO-5658623|reactome:R-RNO-5673001|reactome:R-RNO-6811558	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:uHI6DblbUYteYRYHhUpATP/vXI010116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q9QX79	intact:EBI-1379423	intact:EBI-15347949|uniprotkb:F1LN83	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:fetub_rat(display_long)|uniprotkb:Fetub(gene name)|psi-mi:Fetub(display_short)|uniprotkb:Fetuin-like protein IRL685(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|refseq:NP_445800.2|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR025764|interpro:IPR001363(Proteinase inhibitor I25C, fetuin, conserved site)|rgd:69293	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:UkSWRNC70mTntrBEMHc6O7YjAAo10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P13599	intact:EBI-1379423	intact:EBI-1031194|ensembl:ENSRNOP00000027944	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:fcgrn_rat(display_long)|uniprotkb:Fcgrt(gene name)|psi-mi:Fcgrt(display_short)|uniprotkb:Fcrn(gene name synonym)|uniprotkb:Neonatal Fc receptor(gene name synonym)|uniprotkb:IgG Fc fragment receptor transporter alpha chain(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_006229105.1|rgd:61811|refseq:NP_203502.1|ensembl:ENSRNOG00000020583(gene)|ensembl:ENSRNOT00000027944(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0006959"(humoral immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019770"(IgG receptor activity)|go:"GO:0019864"(IgG binding)|go:"GO:0030881"(beta-2-microglobulin binding)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|rcsb pdb:1FRT|rcsb pdb:1I1A|rcsb pdb:2FRT|rcsb pdb:3FRU|refseq:XP_008757565.1	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:d06EPJhg8RhFDQ4jCj17ZMTQyf810116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P06494	intact:EBI-1379423	intact:EBI-15347848|uniprotkb:Q6P732	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:erbb2_rat(display_long)|uniprotkb:Epidermal growth factor receptor-related protein(gene name synonym)|uniprotkb:Erbb2(gene name)|psi-mi:Erbb2(display_short)|uniprotkb:Neu(gene name synonym)|uniprotkb:Proto-oncogene Neu(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)|uniprotkb:p185erbB2(gene name synonym)|uniprotkb:p185neu(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032570"(response to progesterone)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038143"("ERBB3:ERBB2 complex")|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043586"(tongue development)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0060056"(mammary gland involution)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|reactome:R-RNO-9652282|reactome:R-RNO-1227986|reactome:R-RNO-1250196|reactome:R-RNO-1257604|reactome:R-RNO-1963640|reactome:R-RNO-1963642|reactome:R-RNO-416572|reactome:R-RNO-5673001|reactome:R-RNO-6785631|reactome:R-RNO-6811558|reactome:R-RNO-8847993|reactome:R-RNO-8863795|rcsb pdb:1IIJ|rcsb pdb:1N8Y|rcsb pdb:2J1H|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR032778|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|rgd:2561|interpro:IPR036941	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:/XXBztZIHwE6Xai3vx8B/JoXDps10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P97675	intact:EBI-1379423	intact:EBI-15347809|ensembl:ENSRNOP00000018695|uniprotkb:P70641|uniprotkb:P97676|uniprotkb:Q4V8L6|uniprotkb:Q63490	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:enpp3_rat(display_long)|uniprotkb:B10(gene name synonym)|uniprotkb:Phosphodiesterase I beta(gene name synonym)|uniprotkb:Phosphodiesterase I/nucleotide pyrophosphatase 3(gene name synonym)|uniprotkb:RB13-6 antigen(gene name synonym)|uniprotkb:Enpp3(gene name)|psi-mi:Enpp3(display_short)|uniprotkb:Pdnp3(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000013791(gene)|interpro:IPR001604(DNA/RNA non-specific endonuclease)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR020821|interpro:IPR036024|rcsb pdb:6F2T|rcsb pdb:6F2V|rcsb pdb:6F2Y|rcsb pdb:6F30|rcsb pdb:6F33|rcsb pdb:6G4G|interpro:IPR001212(Somatomedin B)|ensembl:ENSRNOT00000018695(transcript)|go:"GO:0002276"(basophil activation involved in immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004551"(nucleotide diphosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033007"(negative regulation of mast cell activation involved in immune response)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051150"(regulation of smooth muscle cell differentiation)|go:"GO:0070667"(negative regulation of mast cell proliferation)|refseq:NP_062243.2|rgd:708511	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:iQ/J99xcW/4ahnVXu+m0rr4Emkg10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q924C3	intact:EBI-1379423	intact:EBI-15347772|uniprotkb:Q91XQ3|uniprotkb:Q920C8	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:enpp1_rat(display_long)|uniprotkb:Phosphodiesterase I/nucleotide pyrophosphatase 1(gene name synonym)|uniprotkb:Plasma-cell membrane glycoprotein PC-1(gene name synonym)|uniprotkb:Enpp1(gene name)|psi-mi:Enpp1(display_short)|uniprotkb:Npps(gene name synonym)|uniprotkb:Pc1(gene name synonym)|uniprotkb:Pdnp1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046849"(bone remodeling)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0106177"(cyclic-GMP-AMP hydrolase activity)|go:"GO:1990787"(negative regulation of hh target transcription factor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030505"(inorganic diphosphate transport)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0030730"(sequestering of triglyceride)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0006955"(immune response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0021756"(striatum development)|go:"GO:0005524"(ATP binding)|go:"GO:0001889"(liver development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004551"(nucleotide diphosphatase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005509"(calcium ion binding)|interpro:IPR029890|reactome:R-RNO-196843|refseq:NP_445987.1|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR001604(DNA/RNA non-specific endonuclease)|interpro:IPR020821|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR020436|interpro:IPR001212(Somatomedin B)|rgd:628825|interpro:IPR036024	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:S3ol7To0JDAB/f8RGF0TUYe7hvg10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P04764	intact:EBI-1379423	intact:EBI-915852|uniprotkb:Q66HI3|uniprotkb:Q6AYV3|uniprotkb:Q6P504|ensembl:ENSRNOP00000024106|ensembl:ENSRNOP00000073191	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:enoa_rat(display_long)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2553|refseq:NP_001103378.1|refseq:NP_036686.2|ensembl:ENSRNOG00000017895(gene)|ensembl:ENSRNOT00000024106(transcript)|ensembl:ENSRNOT00000081579(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P04764|reactome:R-RNO-70171|reactome:R-RNO-70263	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:JPjYBxy1gOmhfZso6+adhg5N8UM10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P42893	intact:EBI-1379423	intact:EBI-15347728|uniprotkb:Q9WUY8|uniprotkb:Q9WUY9	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:ece1_rat(display_long)|uniprotkb:Ece1(gene name)|psi-mi:Ece1(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0001666"(response to hypoxia)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007507"(heart development)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010814"(substance P catabolic process)|go:"GO:0010815"(bradykinin catabolic process)|go:"GO:0010816"(calcitonin catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0034959"(endothelin maturation)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0042447"(hormone catabolic process)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043583"(ear development)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0035994"(response to muscle stretch)|reactome:R-RNO-375276|interpro:IPR029734|interpro:IPR042089|interpro:IPR024079|interpro:IPR000718(Peptidase M13, neprilysin)|interpro:IPR018497|interpro:IPR008753(Peptidase M13)|rgd:620293	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:aABAwXZe473zZQQrNQHMiww1vzA10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q62904	intact:EBI-1379423	intact:EBI-15347700	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:dhb7_rat(display_long)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 7(gene name synonym)|uniprotkb:Estradiol 17-beta-dehydrogenase 7(gene name synonym)|uniprotkb:PRL receptor-associated protein(gene name synonym)|uniprotkb:3-keto-steroid reductase(gene name synonym)|uniprotkb:Dihydrotestosterone oxidoreductase(gene name synonym)|uniprotkb:Hsd17b7(gene name)|psi-mi:Hsd17b7(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005148"(prolactin receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006703"(estrogen biosynthetic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0047024"(5alpha-androstane-3beta,17beta-diol dehydrogenase activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|go:"GO:1990637"(response to prolactin)|interpro:IPR042829|reactome:R-RNO-191273|refseq:NP_058931.1|interpro:IPR002347(Glucose/ribitol dehydrogenase)|rgd:2837|interpro:IPR036291	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:Fwt4O6Zx7A7lh35lgvYR7/rmVvc10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q5M875	intact:EBI-1379423	intact:EBI-15347680|ensembl:ENSRNOP00000029333	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:dhb13_rat(display_long)|uniprotkb:Short-chain dehydrogenase/reductase 9(gene name synonym)|uniprotkb:Hsd17b13(gene name)|psi-mi:Hsd17b13(display_short)|uniprotkb:Scdr9(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000002212(gene)|ensembl:ENSRNOT00000038188(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0016229"(steroid dehydrogenase activity)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|reactome:R-RNO-8964572|refseq:NP_001009684.1|rgd:1359553	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:40YV4RJmdxi3nEquGs5vTtP1FTg10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q6P7R8	intact:EBI-1379423	intact:EBI-15347647|ensembl:ENSRNOP00000012806|uniprotkb:Q9Z1B9	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:dhb12_rat(display_long)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 12(gene name synonym)|uniprotkb:3-ketoacyl-CoA reductase(gene name synonym)|uniprotkb:Estradiol 17-beta-dehydrogenase 12(gene name synonym)|uniprotkb:Hsd17b12(gene name)|psi-mi:Hsd17b12(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000009630(gene)|ensembl:ENSRNOT00000012806(transcript)|go:"GO:0001968"(fibronectin binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|reactome:R-RNO-193048|reactome:R-RNO-75876|go:"GO:0102342"(3-oxo-cerotoyl-CoA reductase activity)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006703"(estrogen biosynthetic process)|go:"GO:0008201"(heparin binding)|go:"GO:0009923"(fatty acid elongase complex)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0050062"(long-chain-fatty-acyl-CoA reductase activity)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|go:"GO:0102339"(3-oxo-arachidoyl-CoA reductase activity)|go:"GO:0102340"(3-oxo-behenoyl-CoA reductase activity)|go:"GO:0102341"(3-oxo-lignoceroyl-CoA reductase activity)|go:"GO:0005518"(collagen binding)|refseq:NP_114455.1|refseq:XP_006234661.1|rgd:708367	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:xpixX5CYTj7v5pPjr2JdKRovvmg10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q6AYS8	intact:EBI-1379423	intact:EBI-15347622|ensembl:ENSRNOP00000003004	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:dhb11_rat(display_long)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 11(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase XI(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 8(gene name synonym)|uniprotkb:Hsd17b11(gene name)|psi-mi:Hsd17b11(display_short)|uniprotkb:Dhrs8(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000002210(gene)|ensembl:ENSRNOT00000003004(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006710"(androgen catabolic process)|go:"GO:0016229"(steroid dehydrogenase activity)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|reactome:R-RNO-193144|refseq:NP_001004209.1|refseq:XP_006250689.1|refseq:XP_006250691.1|refseq:XP_017454586.1|rgd:1303235	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:TVjpUQ9/oFgwWVnn4qpWvfHp4fE10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P08033	intact:EBI-1379423	intact:EBI-15186211|ensembl:ENSRNOP00000068248	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:cxb1_rat(display_long)|uniprotkb:Connexin-32(gene name synonym)|uniprotkb:GAP junction 28 kDa liver protein(gene name synonym)|uniprotkb:Gjb1(gene name)|psi-mi:Gjb1(display_short)|uniprotkb:Cxn-32(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR019570|interpro:IPR038359|reactome:R-RNO-190704|ensembl:ENSRNOG00000003746(gene)|ensembl:ENSRNOT00000076816(transcript)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007154"(cell communication)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015868"(purine ribonucleotide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1905867"(epididymis development)|interpro:IPR000500(Connexins)|interpro:IPR002267("Gap junction beta-1 protein (Cx32)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|refseq:NP_058947.1|refseq:XP_008771477.1|refseq:XP_017457434.1|rgd:61926	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:x3V62arafAbrMJrHBVC9hCzMfv410116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:B5D5N9	intact:EBI-1379423	intact:EBI-15186164|ensembl:ENSRNOP00000015127|uniprotkb:B5D5P0	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:ctr2_rat(display_long)|uniprotkb:Low affinity cationic amino acid transporter 2(gene name synonym)|uniprotkb:Solute carrier family 7 member 2(gene name synonym)|uniprotkb:Slc7a2(gene name)|psi-mi:Slc7a2(display_short)|uniprotkb:Atrc2(gene name synonym)|uniprotkb:Cat2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOT00000015127(transcript)|go:"GO:0000064"(L-ornithine transmembrane transporter activity)|go:"GO:0002537"(nitric oxide production involved in inflammatory response)|go:"GO:0005886"(plasma membrane)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|ensembl:ENSRNOG00000011016(gene)|go:"GO:0015181"|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015809"|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|go:"GO:0042116"(macrophage activation)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|go:"GO:0097638"(L-arginine import across plasma membrane)|go:"GO:1902023"|go:"GO:1903352"(L-ornithine transmembrane transport)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004755(Cationic amino acid transport permease)|interpro:IPR029485|mint:B5D5N9|reactome:R-RNO-352230|refseq:NP_001128158.1|refseq:NP_072141.2|rgd:68387	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:rhzF/yjx/SYNEDYtsLMV+3kXpEU10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q5M848	intact:EBI-1379423	intact:EBI-9700451	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:crcm1_rat(display_long)|uniprotkb:Orai1(gene name)|psi-mi:Orai1(display_short)|uniprotkb:Cracm1(gene name synonym)|uniprotkb:Tmem142a(gene name synonym)|uniprotkb:Protein orai-1(gene name synonym)|uniprotkb:Transmembrane protein 142A(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001014004.1|interpro:IPR012446(Protein of unknown function DUF1650)|rgd:1311873|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030426"(growth cone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:7DhIGR6sq6d9A3m6/u8kotOXZZM10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P22734	intact:EBI-1379423	intact:EBI-15186055|ensembl:ENSRNOP00000043148	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:comt_rat(display_long)|uniprotkb:Comt(gene name)|psi-mi:Comt(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5P9V|rcsb pdb:5P9W|rcsb pdb:5P9X|rcsb pdb:5P9Y|rcsb pdb:5P9Z|rcsb pdb:5PA0|rcsb pdb:5PA1|rcsb pdb:5PA2|rcsb pdb:5PA3|rcsb pdb:5PA4|rcsb pdb:5PA5|rcsb pdb:5PA6|rcsb pdb:5PA7|rcsb pdb:6GY1|rcsb pdb:6LFE|reactome:R-RNO-156581|reactome:R-RNO-379397|reactome:R-RNO-379398|rcsb pdb:5P9U|ensembl:ENSRNOG00000001889(gene)|ensembl:ENSRNOT00000050269(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0007614"(short-term memory)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0016206"(catechol O-methyltransferase activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032259"(methylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032502"(developmental process)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042424"(catecholamine catabolic process)|go:"GO:0042493"|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043627"(response to estrogen)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:0046498"(S-adenosylhomocysteine metabolic process)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0048265"(response to pain)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050668"(positive regulation of homocysteine metabolic process)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0102084"(L-dopa O-methyltransferase activity)|go:"GO:0102938"(orcinol O-methyltransferase activity)|interpro:IPR002935(O-methyltransferase, family 3)|interpro:IPR017128(Catechol O-methyltransferase, eukaryotic)|interpro:IPR029063|rcsb pdb:1H1D|rcsb pdb:1JR4|rcsb pdb:1VID|rcsb pdb:2CL5|rcsb pdb:2ZLB|rcsb pdb:2ZTH|rcsb pdb:2ZVJ|rcsb pdb:3A7D|rcsb pdb:3HVH|rcsb pdb:3HVJ|rcsb pdb:3HVK|rcsb pdb:3NW9|rcsb pdb:3NWB|rcsb pdb:3NWE|rcsb pdb:3OE4|rcsb pdb:3OE5|rcsb pdb:3OZR|rcsb pdb:3OZS|rcsb pdb:3OZT|rcsb pdb:3R6T|rcsb pdb:3S68|rcsb pdb:3U81|rcsb pdb:4P7G|rcsb pdb:4P7J|rcsb pdb:4P7K|rcsb pdb:4PYL|rcsb pdb:4PYM|rcsb pdb:4PYN|rcsb pdb:4PYO|rcsb pdb:4PYQ|rcsb pdb:3HVI|rcsb pdb:5FHQ|rcsb pdb:5FHR|rcsb pdb:5K01|rcsb pdb:5K03|rcsb pdb:5K05|rcsb pdb:5K09|rcsb pdb:5K0B|rcsb pdb:5K0C|rcsb pdb:5K0E|rcsb pdb:5K0F|rcsb pdb:5K0G|rcsb pdb:5K0J|rcsb pdb:5K0L|rcsb pdb:5K0N|rcsb pdb:5LQA|rcsb pdb:5LQC|rcsb pdb:5LQJ|rcsb pdb:5LQK|rcsb pdb:5LQN|rcsb pdb:5LQR|rcsb pdb:5LQU|rcsb pdb:5LR6|rcsb pdb:5P8W|rcsb pdb:5P8X|rcsb pdb:5P8Y|rcsb pdb:5P8Z|rcsb pdb:5P90|rcsb pdb:5P91|rcsb pdb:5P92|rcsb pdb:5P93|rcsb pdb:5P94|rcsb pdb:5P95|rcsb pdb:5P96|rcsb pdb:5P97|rcsb pdb:5P98|rcsb pdb:5P99|rcsb pdb:5P9A|rcsb pdb:5P9B|rcsb pdb:5P9C|rcsb pdb:5P9D|rcsb pdb:5P9E|rcsb pdb:5P9N|rcsb pdb:5P9O|rcsb pdb:5P9P|rcsb pdb:5P9Q|rcsb pdb:5P9R|rcsb pdb:5P9S|rcsb pdb:5P9T|refseq:NP_036663.1|rgd:2379	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:tT2Jb16AyQlMi76XqVU8LZFGs9Y10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q62930	intact:EBI-1379423	intact:EBI-15186031|uniprotkb:Q62957	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:co9_rat(display_long)|uniprotkb:C9(gene name)|psi-mi:C9(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0001906"(cell killing)|go:"GO:0005579"(membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0019835"(cytolysis)|go:"GO:0051260"(protein homooligomerization)|reactome:R-RNO-166665|reactome:R-RNO-977606|interpro:IPR036055|interpro:IPR036383|refseq:NP_476487.1|interpro:IPR009030(Growth factor, receptor)|interpro:IPR023415|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR001862(Membrane attack complex component/perforin/complement C9)|interpro:IPR020864|interpro:IPR020863|interpro:IPR000884(Thrombospondin, type I)|rgd:620319|interpro:IPR037567	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:aKzq/HgH4953Ke7IWwnNHUX3nPc10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P55314	intact:EBI-1379423	intact:EBI-15185997|ensembl:ENSRNOP00000010100|uniprotkb:Q5EB58	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:co8b_rat(display_long)|uniprotkb:Complement component 8 subunit beta(gene name synonym)|uniprotkb:C8b(gene name)|psi-mi:C8b(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000007639(gene)|ensembl:ENSRNOT00000010100(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005579"(membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0019835"(cytolysis)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001862(Membrane attack complex component/perforin/complement C9)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR020863|interpro:IPR020864|interpro:IPR023415|interpro:IPR036055|interpro:IPR036383|interpro:IPR037566|reactome:R-RNO-166665|reactome:R-RNO-977606|refseq:NP_001178688.1|refseq:XP_006238557.1|rgd:2239	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:6YP3+h14QYU9KndxsOkS9cTrXwc10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P08649	intact:EBI-1379423	intact:EBI-6372987|uniprotkb:Q62895|uniprotkb:Q8R403	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:co4_rat(display_long)|uniprotkb:C4(gene name)|psi-mi:C4(display_short)|uniprotkb:C4a(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR018081|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR019742|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|refseq:NP_113692.2|rgd:620005|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|reactome:R-RNO-166663|reactome:R-RNO-174577|reactome:R-RNO-381426|reactome:R-RNO-8957275|reactome:R-RNO-977606|interpro:IPR013783(Immunoglobulin-like fold)|mint:P08649|interpro:IPR036595|interpro:IPR037569|interpro:IPR040839|interpro:IPR041555	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:OGC90QZT9DyEf1o+RPjGHhQ7Tcg10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q6AXX6	intact:EBI-1379423	intact:EBI-15185964|ensembl:ENSRNOP00000014819|uniprotkb:P85300	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:pxl2a_rat(display_long)|uniprotkb:Prxl2a(gene name)|psi-mi:Prxl2a(display_short)|uniprotkb:Fam213a(gene name synonym)|uniprotkb:Pamm(gene name synonym)|uniprotkb:Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes(gene name synonym)|uniprotkb:Shp1(gene name synonym)|uniprotkb:Sperm head protein 1(gene name synonym)|uniprotkb:Redox-regulatory protein FAM213A(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000011140(gene)|ensembl:ENSRNOT00000014819(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0016209"(antioxidant activity)|interpro:IPR032801|interpro:IPR032802|interpro:IPR036249|mint:Q6AXX6|go:"GO:0045670"(regulation of osteoclast differentiation)|refseq:NP_001014162.1|refseq:XP_006252853.1|rgd:1309676	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:Tnbl3GNIUDyvJ64sU2mgQxM/llc10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P13635	intact:EBI-1379423	intact:EBI-5746846|uniprotkb:Q64719	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:ceru_rat(display_long)|uniprotkb:Cp(gene name)|psi-mi:Cp(display_short)|uniprotkb:Ferroxidase(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR033138|rgd:2387|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR002355(Multicopper oxidase, copper-binding site)|interpro:IPR008972(Cupredoxin)|interpro:IPR024715|rcsb pdb:5N0K|rcsb pdb:5N4L|reactome:R-RNO-381426|reactome:R-RNO-425410|reactome:R-RNO-8957275|reactome:R-RNO-917937|go:"GO:0001889"(liver development)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007595"(lactation)|go:"GO:0015679"(plasma membrane copper ion transport)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0046688"(response to copper ion)|go:"GO:0051087"(chaperone binding)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060056"(mammary gland involution)|go:"GO:0030324"(lung development)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:M/76X5xvjFYHuDV69kOoY21xQaM10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P97829	intact:EBI-1379423	intact:EBI-15185922|ensembl:ENSRNOP00000050938|ensembl:ENSRNOP00000071430|uniprotkb:O35294	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:cd47_rat(display_long)|uniprotkb:Integrin-associated protein(gene name synonym)|uniprotkb:Cd47(gene name)|psi-mi:Cd47(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000001964(gene)|ensembl:ENSRNOT00000050142(transcript)|ensembl:ENSRNOT00000078434(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008228"(opsonization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070487"(monocyte aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904669"(ATP export)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000439"(positive regulation of monocyte extravasation)|interpro:IPR006704(CD47 integrin associated protein)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013147(CD47 transmembrane)|interpro:IPR013270(CD47 immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR037805|mint:P97829|reactome:R-RNO-202733|reactome:R-RNO-216083|reactome:R-RNO-391160|reactome:R-RNO-6798695|go:"GO:0032653"(regulation of interleukin-10 production)|refseq:NP_062068.1|rgd:2308	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:NDbHpeXvgK2ywSf2y9vmcTC0flU10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q07969	intact:EBI-1379423	intact:EBI-15185850|uniprotkb:Q925W0	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:cd36_rat(display_long)|uniprotkb:Adipocyte membrane protein(gene name synonym)|uniprotkb:Fatty acid translocase(gene name synonym)|uniprotkb:Fatty acid transport protein(gene name synonym)|uniprotkb:Glycoprotein IIIb(gene name synonym)|uniprotkb:PAS IV(gene name synonym)|uniprotkb:PAS-4(gene name synonym)|uniprotkb:Platelet glycoprotein IV(gene name synonym)|uniprotkb:Cd36(gene name)|psi-mi:Cd36(display_short)|uniprotkb:Fat(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090208"(positive regulation of triglyceride metabolic process)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098900"(regulation of action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:0150024"(oxidised low-density lipoprotein particle clearance)|go:"GO:0150025"(oxidised low-density lipoprotein particle receptor activity)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990379"(lipid transport across blood-brain barrier)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:2000334"(positive regulation of blood microparticle formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000121"(regulation of removal of superoxide radicals)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0005739"(mitochondrion)|go:"GO:0009617"(response to bacterium)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014823"(response to activity)|go:"GO:0015636"(short-chain fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0015912"(short-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019915"(lipid storage)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031526"(brush border membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033993"(response to lipid)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034381"(plasma lipoprotein particle clearance)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0030301"(cholesterol transport)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070508"(cholesterol import)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0070543"(response to linoleic acid)|go:"GO:0070892"(lipoteichoic acid immune receptor activity)|go:"GO:0071221"(cellular response to bacterial lipopeptide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0050892"(intestinal absorption)|reactome:R-RNO-114608|reactome:R-RNO-3000471|reactome:R-RNO-434313|reactome:R-RNO-5686938|reactome:R-RNO-6798695|interpro:IPR005428(Adhesion molecule CD36)|interpro:IPR033076|interpro:IPR002159(CD36 antigen)|rgd:2301	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:Y3TBChrjvgcJ+xGeekLiVnay6WQ10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q63493	intact:EBI-1379423	intact:EBI-15185822	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:cd1d_rat(display_long)|uniprotkb:Cd1d(gene name)|psi-mi:Cd1d(display_short)|uniprotkb:Cd1d1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0001865"(NK T cell differentiation)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030882"(lipid antigen binding)|go:"GO:0030883"(endogenous lipid antigen binding)|go:"GO:0030884"(exogenous lipid antigen binding)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033084"(regulation of immature T cell proliferation in thymus)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042393"(histone binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045087"(innate immune response)|go:"GO:0048006"(antigen processing and presentation, endogenous lipid antigen via MHC class Ib)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0071723"(lipopeptide binding)|go:"GO:0045059"(positive thymic T cell selection)|reactome:R-RNO-198933|interpro:IPR036179|interpro:IPR037055|refseq:NP_058775.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|rgd:2296	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:0w+xKfRGbL6Fb11BQ+t2w3rq0x410116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q5M862	intact:EBI-1379423	intact:EBI-15185806|ensembl:ENSRNOP00000052900	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:cc134_rat(display_long)|uniprotkb:Ccdc134(gene name)|psi-mi:Ccdc134(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR026321|ensembl:ENSRNOG00000007262(gene)|ensembl:ENSRNOT00000056048(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001890"(placenta development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0021591"(ventricular system development)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:1990402"(embryonic liver development)|refseq:NP_001019526.1|refseq:XP_006242175.1|rgd:1559657	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:QoZAfTyp/ExKB4M80S+uJxaCCk010116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q9JHW1	intact:EBI-1379423	intact:EBI-15185776|uniprotkb:O35850	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:cbpd_rat(display_long)|uniprotkb:Metallocarboxypeptidase D(gene name synonym)|uniprotkb:gp180(gene name synonym)|uniprotkb:Cpd(gene name)|psi-mi:Cpd(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR033848|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071352"(cellular response to interleukin-2)|reactome:R-RNO-9696264|reactome:R-RNO-9696273|reactome:R-RNO-432722|interpro:IPR015567(Peptidase M14B, caboxypeptidase D unit2)|refseq:NP_036968.1|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR034224|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|rgd:2393	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:bdjKkmA57T9LZmMd+UPQRlIyyng10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q9EQV9	intact:EBI-1379423	intact:EBI-15185741|ensembl:ENSRNOP00000014909|uniprotkb:Q3B7V3|uniprotkb:Q5BKB8	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:cbpb2_rat(display_long)|uniprotkb:Carboxypeptidase R(gene name synonym)|uniprotkb:Carboxypeptidase U(gene name synonym)|uniprotkb:Thrombin-activable fibrinolysis inhibitor(gene name synonym)|uniprotkb:Cpb2(gene name)|psi-mi:Cpb2(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000010935(gene)|ensembl:ENSRNOT00000014909(transcript)|go:"GO:0003331"(positive regulation of extracellular matrix constituent secretion)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009408"(response to heat)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0042493"|go:"GO:0042730"(fibrinolysis)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097421"(liver regeneration)|go:"GO:2000346"(negative regulation of hepatocyte proliferation)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR003146(Proteinase inhibitor, carboxypeptidase propeptide)|interpro:IPR033849|interpro:IPR036990|reactome:R-RNO-2022377|reactome:R-RNO-977606|refseq:NP_446069.1|rgd:71035	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:LkonNxTQgTS5Q2JT7aJwvQ+ZL1A10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P31211	intact:EBI-1379423	intact:EBI-15185717|ensembl:ENSRNOP00000012500|uniprotkb:Q5M822	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:cbg_rat(display_long)|uniprotkb:Serpin A6(gene name synonym)|uniprotkb:Transcortin(gene name synonym)|uniprotkb:Serpina6(gene name)|psi-mi:Serpina6(display_short)|uniprotkb:Cbg(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005615"(extracellular space)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:2V95|reactome:R-RNO-194002|ensembl:ENSRNOG00000009438(gene)|ensembl:ENSRNOT00000012500(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005496"(steroid binding)|refseq:NP_001009663.1|rgd:1595901	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:tP9HVKVKBkpReTtbocycYfYbl9Q10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:O54800	intact:EBI-1379423	intact:EBI-15185698|uniprotkb:O54801	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:cadh8_rat(display_long)|uniprotkb:Cdh8(gene name)|psi-mi:Cdh8(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0000902"(cell morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009409"(response to cold)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0034332"(adherens junction organization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043679"(axon terminus)|go:"GO:0045296"(cadherin binding)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098978"(glutamatergic synapse)|reactome:R-RNO-418990|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR027397|rgd:69286|interpro:IPR039808	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:nW51DvhvzP1KP2OEVXQHDwH4gpA10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P31722	intact:EBI-1379423	intact:EBI-15185680|uniprotkb:Q5RJZ8	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:c1qc_rat(display_long)|uniprotkb:C1qc(gene name)|psi-mi:C1qc(display_short)|uniprotkb:C1qg(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	mint:P31722|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|reactome:R-RNO-173623|reactome:R-RNO-977606|reactome:R-RNO-166663|refseq:NP_001008524.1|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|rgd:1306828	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:JEQN8sBWiMYg6oRSq6mKcKyiHa410116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P23562	intact:EBI-1379423	intact:EBI-15185633	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:b3at_rat(display_long)|uniprotkb:Anion exchange protein 1(gene name synonym)|uniprotkb:Solute carrier family 4 member 1(gene name synonym)|uniprotkb:Slc4a1(gene name)|psi-mi:Slc4a1(display_short)|uniprotkb:Ae1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0048821"(erythrocyte development)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904539"(negative regulation of glycolytic process through fructose-6-phosphate)|go:"GO:0003779"(actin binding)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0007596"(blood coagulation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010037"(response to carbon dioxide)|go:"GO:0010446"(response to alkaline pH)|go:"GO:0010447"(response to acidic pH)|go:"GO:0014704"(intercalated disc)|go:"GO:0014823"(response to activity)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0019899"(enzyme binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030018"(Z disc)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045852"(pH elevation)|go:"GO:0015108"(chloride transmembrane transporter activity)|reactome:R-RNO-425381|reactome:R-RNO-1237044|refseq:NP_036783.2|refseq:XP_008766168.1|interpro:IPR001717(Anion exchange protein)|interpro:IPR002977(Anion exchange protein 1)|interpro:IPR018241|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR016152(Phosphotransferase/anion transporter)|rgd:3710|reactome:R-RNO-1247673	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:QcGLuDL8UcZ1+aml+HzkCDR6lwo10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P07151	intact:EBI-1379423	intact:EBI-1031212|ensembl:ENSRNOP00000023017	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:b2mg_rat(display_long)|uniprotkb:B2m(gene name)|psi-mi:B2m(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_036644.1|rgd:2189|ensembl:ENSRNOG00000017123(gene)|ensembl:ENSRNOT00000023017(transcript)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007611"(learning or memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0042026"(protein refolding)|go:"GO:0042493"|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071283"("cellular response to iron(III) ion")|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904434"(positive regulation of ferrous iron binding)|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2000978"(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|rcsb pdb:1ED3|rcsb pdb:1FRT|rcsb pdb:1I1A|rcsb pdb:1KJM|rcsb pdb:1KJV|rcsb pdb:2FRT|rcsb pdb:3FRU|rcsb pdb:6NF7|reactome:R-RNO-1236974|reactome:R-RNO-1236977|reactome:R-RNO-198933|reactome:R-RNO-2172127|reactome:R-RNO-2424491|reactome:R-RNO-6798695|reactome:R-RNO-983170	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:L1E4C8UB88GfVwa4DKn38Q090S410116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q99J86	intact:EBI-1379423	intact:EBI-15185591|ensembl:ENSRNOP00000028847|uniprotkb:Q99PW0	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:atrn_rat(display_long)|uniprotkb:Protein zitter(gene name synonym)|uniprotkb:Atrn(gene name)|psi-mi:Atrn(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0038023"(signaling receptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042552"(myelination)|go:"GO:0043473"(pigmentation)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001304(C-type lectin)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR016201(Plexin-like fold)|interpro:IPR035914|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|ensembl:ENSRNOG00000021240(gene)|ensembl:ENSRNOT00000028847(transcript)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021549"(cerebellum development)|go:"GO:0030246"(carbohydrate binding)|refseq:NP_112641.1|rgd:69063	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:lMW2fpS2A7Hvgch+NOF5DtYefbA10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q64535	intact:EBI-1379423	intact:EBI-15185541|uniprotkb:Q63676|uniprotkb:Q9JLY3	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:atp7b_rat(display_long)|uniprotkb:Copper pump 2(gene name synonym)|uniprotkb:Pineal night-specific ATPase(gene name synonym)|uniprotkb:Wilson disease-associated protein homolog(gene name synonym)|uniprotkb:Atp7b(gene name)|psi-mi:Atp7b(display_short)|uniprotkb:Pina(gene name synonym)|uniprotkb:Wnd(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR044492|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006825"(copper ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015677"(copper ion import)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043682"(P-type divalent copper transporter activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0046688"(response to copper ion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051591"(response to cAMP)|go:"GO:0060003"(copper ion export)|go:"GO:0070160"(tight junction)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:1990637"(response to prolactin)|go:"GO:0140581"(P-type monovalent copper transporter activity)|reactome:R-RNO-936837|interpro:IPR018303|interpro:IPR023298|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR017969|interpro:IPR006122(Copper ion-binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR027256|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR023299|rgd:2180|interpro:IPR036163|interpro:IPR036412	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:/ASqGymgOlem+2YntkuUkR1b0TI10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P11505	intact:EBI-1379423	intact:EBI-11689586|uniprotkb:Q63442|uniprotkb:Q9R1L7	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:at2b1_rat(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)|uniprotkb:Atp2b1(gene name)|psi-mi:Atp2b1(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	mint:P11505|refseq:NP_445763.1|interpro:IPR022141|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR023299|interpro:IPR018303|interpro:IPR023298|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|rgd:621303|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1901660"(calcium ion export)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|reactome:R-RNO-418359|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|interpro:IPR023214|interpro:IPR044492|interpro:IPR030320|interpro:IPR036412	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:qd0uJavojqO86ByVuj5YhI/lROE10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q63377	intact:EBI-1379423	intact:EBI-918577|ensembl:ENSRNOP00000015475	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:at1b3_rat(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:Atp1b3(gene name)|psi-mi:Atp1b3(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_037045.1|rgd:2172|ensembl:ENSRNOG00000011501(gene)|ensembl:ENSRNOT00000015476(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|reactome:R-RNO-210991|reactome:R-RNO-5578775|reactome:R-RNO-936837	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:GhcaevDyyzsnN/096rE3vq3hBOI10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P07340	intact:EBI-1379423	intact:EBI-2640714|uniprotkb:Q63062|ensembl:ENSRNOP00000003932	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:at1b1_rat(display_long)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2170|refseq:NP_037245.2|ensembl:ENSRNOG00000002934(gene)|ensembl:ENSRNOT00000003932(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001824"(blastocyst development)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:0030315"(T-tubule)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P07340|reactome:R-RNO-210991|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:1990573"(potassium ion import across plasma membrane)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:gJJ7PU6Tz3znT4wWy7GIPSV/x9w10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P06685	intact:EBI-1379423	intact:EBI-915951|uniprotkb:Q64609|ensembl:ENSRNOP00000045650	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:at1a1_rat(display_long)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2167|refseq:NP_036636.1|ensembl:ENSRNOG00000030019(gene)|ensembl:ENSRNOT00000040430(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0015988"(energy coupled proton transmembrane transport, against electrochemical gradient)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P06685|rcsb pdb:1MO7|rcsb pdb:1MO8|reactome:R-RNO-5578775|reactome:R-RNO-936837	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:Chn3+kL+xhJd9yHk1JWVxqmhS4A10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P07824	intact:EBI-1379423	intact:EBI-916084|uniprotkb:Q5BK93|ensembl:ENSRNOP00000017911	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:argi1_rat(display_long)|uniprotkb:Arg1(gene name)|psi-mi:Arg1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|interpro:IPR020855|interpro:IPR023696|rcsb pdb:1D3V|rcsb pdb:1HQ5|rcsb pdb:1HQF|rcsb pdb:1HQG|rcsb pdb:1HQH|rcsb pdb:1HQX|rcsb pdb:1P8M|rcsb pdb:1P8N|rcsb pdb:1P8O|rcsb pdb:1P8P|rcsb pdb:1P8Q|rcsb pdb:1P8R|rcsb pdb:1P8S|rcsb pdb:1R1O|rcsb pdb:1RLA|rcsb pdb:1T4P|rcsb pdb:1T4R|rcsb pdb:1T4S|rcsb pdb:1T4T|rcsb pdb:1T5F|rcsb pdb:1T5G|rcsb pdb:1TA1|rcsb pdb:1TBH|rcsb pdb:1TBJ|rcsb pdb:1TBL|rcsb pdb:1ZPE|rcsb pdb:1ZPG|rcsb pdb:2RLA|rcsb pdb:3E8Q|rcsb pdb:3E8Z|rcsb pdb:3E9B|rcsb pdb:3RLA|rcsb pdb:4RLA|rcsb pdb:5RLA|reactome:R-RNO-6798695|reactome:R-RNO-70635|ensembl:ENSRNOG00000013304(gene)|ensembl:ENSRNOT00000017911(transcript)|go:"GO:0043200"(response to amino acid)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006525"(arginine metabolic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0009611"(response to wounding)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|rgd:2150|refseq:NP_058830.2	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:RKOj1hwJ7LsEj9EUAkhlHjBkvYA10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P29975	intact:EBI-1379423	intact:EBI-15185420|ensembl:ENSRNOP00000015692|uniprotkb:Q5EB50|uniprotkb:Q7TN36	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:aqp1_rat(display_long)|uniprotkb:Aquaporin-CHIP(gene name synonym)|uniprotkb:Water channel protein for red blood cells and kidney proximal tubule(gene name synonym)|uniprotkb:Aqp1(gene name)|psi-mi:Aqp1(display_short)|uniprotkb:Chip28(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOT00000015692(transcript)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003097"(renal water transport)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005372"(water transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005903"(brush border)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006833"(water transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0009725"(response to hormone)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015079"(potassium ion transmembrane transporter activity)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015250"(water channel activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0015696"|go:"GO:0015793"(glycerol transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0020003"(symbiont-containing vacuole)|ensembl:ENSRNOG00000011648(gene)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030104"(water homeostasis)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030184"(nitric oxide transmembrane transporter activity)|go:"GO:0030185"(nitric oxide transport)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031526"(brush border membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0032940"(secretion by cell)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0033363"(secretory granule organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035378"(carbon dioxide transmembrane transport)|go:"GO:0035379"(carbon dioxide transmembrane transporter activity)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0042476"(odontogenesis)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0043679"(axon terminus)|go:"GO:0044241"(lipid digestion)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046878"(positive regulation of saliva secretion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051458"(corticotropin secretion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070295"(renal water absorption)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0072220"(metanephric descending thin limb development)|go:"GO:0072230"(metanephric proximal straight tubule development)|go:"GO:0072232"(metanephric proximal convoluted tubule segment 2 development)|go:"GO:0072239"(metanephric glomerulus vasculature development)|go:"GO:0045177"(apical part of cell)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR023274|interpro:IPR034294|reactome:R-RNO-1237044|reactome:R-RNO-1247673|reactome:R-RNO-432040|reactome:R-RNO-432047|go:"GO:0085018"(obsolete maintenance of symbiont-containing vacuole by host)|refseq:NP_036910.1|rgd:2141	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:4Pj8cWDFjBum9aysn30uVat/34410116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P26644	intact:EBI-1379423	intact:EBI-15185397	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:apoh_rat(display_long)|uniprotkb:Apolipoprotein H(gene name synonym)|uniprotkb:Beta-2-glycoprotein I(gene name synonym)|uniprotkb:Apoh(gene name)|psi-mi:Apoh(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0042627"(chylomicron)|go:"GO:0042802"(identical protein binding)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051917"(regulation of fibrinolysis)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0060230"(lipoprotein lipase activator activity)|go:"GO:0060268"(negative regulation of respiratory burst)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007568"(aging)|go:"GO:0007596"(blood coagulation)|go:"GO:0007597"(blood coagulation, intrinsic pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0034014"(response to triglyceride)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|reactome:R-RNO-114608|interpro:IPR015104(Beta-2-glycoprotein-1 fifth domain)|interpro:IPR000436(Sushi/SCR/CCP)|rgd:1310625|interpro:IPR035976	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:RL7ig2+UXGfnEJAFkarGlthfBus10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P02650	intact:EBI-1379423	intact:EBI-1638221|ensembl:ENSRNOP00000050968|ensembl:ENSRNOP00000068937	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:apoe_rat(display_long)|uniprotkb:Apoe(gene name)|psi-mi:Apoe(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2138|refseq:NP_620183.2|refseq:NP_001257610.1|refseq:NP_001257611.1|refseq:NP_001257612.1|refseq:NP_001257613.1|ensembl:ENSRNOG00000018454(gene)|ensembl:ENSRNOT00000041891(transcript)|ensembl:ENSRNOT00000091574(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010877"(lipid transport involved in lipid storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016209"(antioxidant activity)|go:"GO:0017038"(protein import)|go:"GO:0019068"(virion assembly)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030425"(dendrite)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032805"(positive regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034447"(very-low-density lipoprotein particle clearance)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046848"(hydroxyapatite binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0046911"(metal chelating activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0051651"(maintenance of location in cell)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061771"(response to caloric restriction)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0071830"(triglyceride-rich lipoprotein particle clearance)|go:"GO:0071831"(intermediate-density lipoprotein particle clearance)|go:"GO:0072359"(circulatory system development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0090209"(negative regulation of triglyceride metabolic process)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1903002"(positive regulation of lipid transport across blood-brain barrier)|go:"GO:1904421"(response to D-galactosamine)|go:"GO:1905855"(positive regulation of heparan sulfate binding)|go:"GO:1905860"(positive regulation of heparan sulfate proteoglycan binding)|go:"GO:1905890"(regulation of cellular response to very-low-density lipoprotein particle stimulus)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1990777"(lipoprotein particle)|go:"GO:2000822"(regulation of behavioral fear response)|interpro:IPR000074(Apolipoprotein A1/A4/E)|reactome:R-RNO-3000480|reactome:R-RNO-381426|reactome:R-RNO-8957275|reactome:R-RNO-8963888|reactome:R-RNO-8963901|reactome:R-RNO-8964026|reactome:R-RNO-8964058|reactome:R-RNO-975634	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:ERgpYnyTQFwZp5c5F1hi5oSwg0I10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q7TMA5	intact:EBI-1379423	intact:EBI-15185298|ensembl:ENSRNOP00000039779	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:apob_rat(display_long)|uniprotkb:Apob(gene name)|psi-mi:Apob(display_short)|uniprotkb:Aa1064(orf name)|uniprotkb:Ac1-060(orf name)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010033"(response to organic substance)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR013763(Cyclin-related)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR022176|interpro:IPR036915|reactome:R-RNO-202733|reactome:R-RNO-3000471|reactome:R-RNO-3000480|reactome:R-RNO-3000497|reactome:R-RNO-381426|reactome:R-RNO-432142|reactome:R-RNO-5686938|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866423|reactome:R-RNO-8957275|reactome:R-RNO-8963888|reactome:R-RNO-8963901|reactome:R-RNO-8964026|reactome:R-RNO-8964038|reactome:R-RNO-8964041|reactome:R-RNO-8964046|reactome:R-RNO-9707616|reactome:R-RNO-975634|ensembl:ENSRNOG00000005542(gene)|ensembl:ENSRNOT00000046811(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|refseq:NP_062160.2|dip:DIP-29910N|rgd:2129	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:vQoer433jh9eD6a/5SSRN/IVUjQ10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P48037	intact:EBI-1379423	intact:EBI-917595	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:anxa6_rat(display_long)|uniprotkb:Annexin-6(gene name synonym)|uniprotkb:Annexin VI(gene name synonym)|uniprotkb:Calcium-binding protein 65/67(gene name synonym)|uniprotkb:Anxa6(gene name)|psi-mi:Anxa6(display_short)|uniprotkb:Anx6(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:621172|interpro:IPR001464(Annexin)|interpro:IPR018502|interpro:IPR018252|interpro:IPR002393(Annexin, type VI)|interpro:IPR037104|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003418"(growth plate cartilage chondrocyte differentiation)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0008289"(lipid binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046903"(secretion)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051283"(negative regulation of sequestering of calcium ion)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0097190"(apoptotic signaling pathway)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:hWGMXJuio4/6/NDpkmRIDicrcbk10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P14669	intact:EBI-1379423	intact:EBI-15185247|ensembl:ENSRNOP00000063496|uniprotkb:Q642C2	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:anxa3_rat(display_long)|uniprotkb:35-alpha calcimedin(gene name synonym)|uniprotkb:Annexin III(gene name synonym)|uniprotkb:Annexin-3(gene name synonym)|uniprotkb:Lipocortin III(gene name synonym)|uniprotkb:Placental anticoagulant protein III(gene name synonym)|uniprotkb:Anxa3(gene name)|psi-mi:Anxa3(display_short)|uniprotkb:Anx3(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000002045(gene)|ensembl:ENSRNOT00000068134(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0021766"(hippocampus development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0042581"(specific granule)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051054"(positive regulation of DNA metabolic process)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070848"(response to growth factor)|interpro:IPR001464(Annexin)|interpro:IPR002390(Annexin, type III)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|refseq:NP_036955.2|refseq:XP_006250756.1|refseq:XP_006250758.1|rgd:2119	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:uUJg2tRa9tA0joCL/xd0fhr5VlM10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q07936	intact:EBI-1379423	intact:EBI-918209|ensembl:ENSRNOP00000038428	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:anxa2_rat(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:621170|refseq:NP_063970.1|ensembl:ENSRNOG00000010362(gene)|ensembl:ENSRNOT00000038677(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051917"(regulation of fibrinolysis)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|reactome:R-RNO-6798695|reactome:R-RNO-75205	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:SOUcyxKVc0YRMNALClXoYKomQT810116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P07150	intact:EBI-1379423	intact:EBI-916045|uniprotkb:Q64664|ensembl:ENSRNOP00000023664	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:anxa1_rat(display_long)|uniprotkb:Anxa1(gene name)|psi-mi:Anxa1(display_short)|uniprotkb:Anx1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_037036.1|rgd:2118|refseq:XP_008758517.1|ensembl:ENSRNOG00000017469(gene)|ensembl:ENSRNOT00000023664(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009725"(response to hormone)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044849"(estrous cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|reactome:R-RNO-416476|reactome:R-RNO-418594|reactome:R-RNO-444473	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:stwhnd4HyVtBxO/rvSW2UZKYmmA10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P01015	intact:EBI-1379423	intact:EBI-15185142|ensembl:ENSRNOP00000024917	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:angt_rat(display_long)|uniprotkb:Serpin A8(gene name synonym)|uniprotkb:Agt(gene name)|psi-mi:Agt(display_short)|uniprotkb:Serpina8(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR042178|interpro:IPR042185|rcsb pdb:1SMR|rcsb pdb:2WXZ|rcsb pdb:2WY1|reactome:R-RNO-2022377|reactome:R-RNO-375276|reactome:R-RNO-416476|reactome:R-RNO-418594|go:"GO:0034104"(negative regulation of tissue remodeling)|go:"GO:0035106"(operant conditioning)|go:"GO:0035813"(regulation of renal sodium excretion)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042311"(vasodilation)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042756"(drinking behavior)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048144"(fibroblast proliferation)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051969"(regulation of transmission of nerve impulse)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070471"(uterine smooth muscle contraction)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1901201"(regulation of extracellular matrix assembly)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1905010"(positive regulation of L-lysine import across plasma membrane)|go:"GO:1905589"(positive regulation of L-arginine import across plasma membrane)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR000227(Angiotensinogen)|interpro:IPR023796|interpro:IPR033834|interpro:IPR036186|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007588"(excretion)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009651"(response to salt stress)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010536"(positive regulation of activation of Janus kinase activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014824"(artery smooth muscle contraction)|go:"GO:0014873"(response to muscle activity involved in regulation of muscle adaptation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030432"(peristalsis)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031703"(type 2 angiotensin receptor binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|ensembl:ENSRNOG00000018445(gene)|ensembl:ENSRNOT00000024917(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0002019"(regulation of renal output by angiotensin)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002035"(brain renin-angiotensin system)|go:"GO:0003014"(renal system process)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001568"(blood vessel development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0001998"(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:"GO:0001999"(renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure)|go:"GO:0003051"(angiotensin-mediated drinking behavior)|go:"GO:0003331"(positive regulation of extracellular matrix constituent secretion)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|refseq:NP_602308.1|refseq:XP_008770819.1|rgd:2069	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:9mHd+AFro6aQ543Xl3Wu8kCgCes10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q99068	intact:EBI-1379423	intact:EBI-919734|uniprotkb:Q4FZX8|uniprotkb:Q642A1|uniprotkb:Q64723|ensembl:ENSRNOP00000012665	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:amrp_rat(display_long)|uniprotkb:Lrpap1(gene name)|psi-mi:Lrpap1(display_short)|uniprotkb:Low density lipoprotein receptor-related protein-associated protein 1(gene name synonym)|uniprotkb:Gp330-binding 45 kDa protein(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:620700|refseq:NP_001162584.1|ensembl:ENSRNOG00000009313(gene)|ensembl:ENSRNOT00000012665(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0012505"(endomembrane system)|go:"GO:0031904"(endosome lumen)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035473"(lipase binding)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048237"(rough endoplasmic reticulum lumen)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|interpro:IPR009066(Alpha-2-macroglobulin receptor-associated protein, domain 1)|interpro:IPR010483(Alpha-2-macroglobulin RAP, C-terminal)|interpro:IPR036744|interpro:IPR037999|interpro:IPR038001|interpro:IPR038003|mint:Q99068	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:iCszi7bhiu3sGLgNv5dSIQ81m5Q10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q64240	intact:EBI-1379423	intact:EBI-15185101|ensembl:ENSRNOP00000009248|uniprotkb:P19603|uniprotkb:Q63336	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:ambp_rat(display_long)|uniprotkb:Ambp(gene name)|psi-mi:Ambp(display_short)|uniprotkb:Itil(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000006889(gene)|reactome:R-RNO-2168880|ensembl:ENSRNOT00000009248(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019862"(IgA binding)|go:"GO:0020037"(heme binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR002968(Alpha-1-microglobulin)|interpro:IPR012674(Calycin)|interpro:IPR020901|interpro:IPR022272|interpro:IPR029856|interpro:IPR036880|refseq:NP_037033.1|rgd:2102	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:KNsKU9OOwpSbE0ge+C1+c+dxEGY10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P07943	intact:EBI-1379423	intact:EBI-15185049|ensembl:ENSRNOP00000012879	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:aldr_rat(display_long)|uniprotkb:Aldehyde reductase(gene name synonym)|uniprotkb:Akr1b1(gene name)|psi-mi:Akr1b1(display_short)|uniprotkb:Akr1b4(gene name synonym)|uniprotkb:Aldr1(gene name synonym)|uniprotkb:Aldose reductase(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000009513(gene)|ensembl:ENSRNOT00000012879(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005615"(extracellular space)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005996"(monosaccharide metabolic process)|go:"GO:0006061"(sorbitol biosynthetic process)|go:"GO:0009414"(response to water deprivation)|go:"GO:0010033"(response to organic substance)|go:"GO:0018505"(cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0032838"(plasma membrane bounded cell projection cytoplasm)|go:"GO:0033010"(paranodal junction)|go:"GO:0035809"(regulation of urine volume)|go:"GO:0036130"(prostaglandin H2 endoperoxidase reductase activity)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042629"(mast cell granule)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043795"(glyceraldehyde oxidoreductase activity)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0047655"(allyl-alcohol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0047956"(glycerol dehydrogenase [NADP+] activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:0097238"(cellular response to methylglyoxal)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:1901360"(organic cyclic compound metabolic process)|go:"GO:1901653"(cellular response to peptide)|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|reactome:R-RNO-196108|reactome:R-RNO-5652227|refseq:NP_036630.1|rgd:2092	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:nrsZD8jKV6aYvc0lqX+67yc6bzY10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q80W57	intact:EBI-1379423	intact:EBI-15184919|ensembl:ENSRNOP00000009546|ensembl:ENSRNOP00000075138|uniprotkb:Q80ST1|uniprotkb:Q80UR3|uniprotkb:Q80XF3	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:abcg2_rat(display_long)|uniprotkb:Breast cancer resistance protein 1 homolog(gene name synonym)|uniprotkb:Urate exporter(gene name synonym)|uniprotkb:Abcg2(gene name)|psi-mi:Abcg2(display_short)|uniprotkb:Bcrp1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family G member 2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000007041(gene)|ensembl:ENSRNOT00000009546(transcript)|ensembl:ENSRNOT00000088983(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007568"(aging)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010039"(response to iron ion)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR030256|interpro:IPR043926|reactome:R-RNO-189451|reactome:R-RNO-189483|reactome:R-RNO-917937|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0015747"(urate transport)|go:"GO:0015878"(biotin transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019389"(glucuronoside metabolic process)|go:"GO:0031526"(brush border membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032217"(riboflavin transmembrane transporter activity)|go:"GO:0032218"(riboflavin transport)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032868"(response to insulin)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043278"(response to morphine)|go:"GO:0045121"(membrane raft)|go:"GO:0046415"(urate metabolic process)|go:"GO:0051593"(response to folic acid)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1904479"(negative regulation of intestinal absorption)|go:"GO:1904612"(response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1990748"(cellular detoxification)|go:"GO:0042887"(amide transmembrane transporter activity)|refseq:NP_852046.1|refseq:XP_006236634.1|refseq:XP_006236635.1|refseq:XP_006236636.1|refseq:XP_006236638.1|refseq:XP_008761183.1|refseq:XP_017448109.1|rgd:631345	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:/2KWOklNsxIAT9AKcrMeVgjQz/Y10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:O70127	intact:EBI-1379423	intact:EBI-930036	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:abcbb_rat(display_long)|uniprotkb:Abcb11(gene name)|psi-mi:Abcb11(display_short)|uniprotkb:Bsep(gene name synonym)|uniprotkb:Spgp(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 11(gene name synonym)|uniprotkb:Sister of P-glycoprotein(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:619930|refseq:NP_113948.1|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR030278|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|reactome:R-RNO-159418|reactome:R-RNO-193368|go:"GO:0000139"(Golgi membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015126"(canalicular bile acid transmembrane transporter activity)|go:"GO:0015144"(carbohydrate transmembrane transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015722"(canalicular bile acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017144"|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0035690"|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043627"(response to estrogen)|go:"GO:0045177"(apical part of cell)|go:"GO:0045471"(response to ethanol)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0046618"(xenobiotic export)|go:"GO:0046691"(intracellular canaliculus)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0120188"(regulation of bile acid secretion)|go:"GO:0120189"(positive regulation of bile acid secretion)|go:"GO:1904251"(regulation of bile acid metabolic process)|go:"GO:1904486"(response to 17alpha-ethynylestradiol)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:CcB8zd8iM+EBun9D4DF29nmQi4k10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P15823	intact:EBI-1379423	intact:EBI-15185013|uniprotkb:Q63215	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:ada1b_rat(display_long)|uniprotkb:Alpha-1B adrenoreceptor(gene name synonym)|uniprotkb:Adra1b(gene name)|psi-mi:Adra1b(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043627"(response to estrogen)|go:"GO:0045818"(negative regulation of glycogen catabolic process)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001115(Adrenergic receptor, alpha-1B)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0001975"(response to amphetamine)|go:"GO:0001987"(vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0001997"(positive regulation of the force of heart contraction by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007512"(adult heart development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009725"(response to hormone)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035265"(organ growth)|dip:DIP-59867N|rgd:2054|reactome:R-RNO-390696|reactome:R-RNO-416476|reactome:R-RNO-416482	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:v5AffHemwsOIgS5BgARd8tuHy8E10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q99PE7	intact:EBI-1379423	intact:EBI-15184974|ensembl:ENSRNOP00000007174|uniprotkb:Q8CIQ4	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:abcg5_rat(display_long)|uniprotkb:Sterolin-1(gene name synonym)|uniprotkb:Abcg5(gene name)|psi-mi:Abcg5(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000005250(gene)|ensembl:ENSRNOT00000007174(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007584"(response to nutrient)|go:"GO:0007588"(excretion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010949"(negative regulation of intestinal phytosterol absorption)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0043235"(receptor complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045796"(negative regulation of intestinal cholesterol absorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR043926|reactome:R-RNO-1369062|refseq:NP_446206.2|rgd:620298	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:tORXMtBldRLPinYbaioAoau3O7E10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P06238	intact:EBI-1379423	intact:EBI-15184861|ensembl:ENSRNOP00000019346|ensembl:ENSRNOP00000066130|uniprotkb:Q4FZY3	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:a2mg_rat(display_long)|uniprotkb:A2m(gene name)|psi-mi:A2m(display_short)|uniprotkb:A2m1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000028896(gene)|ensembl:ENSRNOG00000045772(gene)|ensembl:ENSRNOT00000019346(transcript)|ensembl:ENSRNOT00000075799(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0001869"(negative regulation of complement activation, lectin pathway)|go:"GO:0002020"(protease binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0007584"(response to nutrient)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR041813|mint:P06238|reactome:R-RNO-114608|reactome:R-RNO-140837|reactome:R-RNO-1474228|reactome:R-RNO-8963896|interpro:IPR001599(Alpha-2-macroglobulin)|go:"GO:0010037"(response to carbon dioxide)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019838"(growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0042802"(identical protein binding)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048403"(brain-derived neurotrophic factor binding)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:1990402"(embryonic liver development)|go:"GO:0009611"(response to wounding)|refseq:NP_036620.2|refseq:XP_003749876.1|rgd:2004	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:MAZi2KkXU2jKuLSeqwT1dNJlrY010116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q9EPH1	intact:EBI-1379423	intact:EBI-15184809|ensembl:ENSRNOP00000006273|uniprotkb:Q5EBD6|uniprotkb:Q9JKL2	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:a1bg_rat(display_long)|uniprotkb:Alpha-1-B glycoprotein(gene name synonym)|uniprotkb:C44(gene name synonym)|uniprotkb:Liver regeneration-related protein 1(gene name synonym)|uniprotkb:A1bg(gene name)|psi-mi:A1bg(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000004692(gene)|ensembl:ENSRNOT00000006273(transcript)|go:"GO:0005576"(extracellular region)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016332(Alpha-1B-glycoprotein/leukocyte immunoglobulin-like receptor)|interpro:IPR036179|reactome:R-RNO-114608|reactome:R-RNO-6798695|refseq:NP_071594.2|rgd:69417	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:UlRCfAFODBWmhOMmhL/onUC0nkM10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P17475	intact:EBI-1379423	intact:EBI-15184775|uniprotkb:Q6AYZ5	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:a1at_rat(display_long)|uniprotkb:Serpina1(gene name)|psi-mi:Serpina1(display_short)|uniprotkb:Alpha-1-antitrypsin(gene name synonym)|uniprotkb:Alpha-1-proteinase inhibitor(gene name synonym)|uniprotkb:Serpin A1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR042178|interpro:IPR042185|reactome:R-RNO-114608|reactome:R-RNO-204005|reactome:R-RNO-381426|reactome:R-RNO-5694530|reactome:R-RNO-6798695|reactome:R-RNO-8957275|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033986"(response to methanol)|go:"GO:0034014"(response to triglyceride)|go:"GO:0034097"(response to cytokine)|go:"GO:0042802"(identical protein binding)|go:"GO:0046687"(response to chromate)|go:"GO:0002020"(protease binding)|go:"GO:1900004"(negative regulation of serine-type endopeptidase activity)|go:"GO:0001666"(response to hypoxia)|refseq:NP_071964.2|refseq:XP_006240518.1|refseq:XP_017449521.1|interpro:IPR023795|interpro:IPR023796|interpro:IPR000215(Protease inhibitor I4, serpin)|rgd:3326|interpro:IPR036186	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:NPCZrR/F9GgVzAZ+OoorK056Ap410116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q794F9	intact:EBI-1379423	intact:EBI-919315	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:4f2_rat(display_long)|uniprotkb:Slc3a2(gene name)|psi-mi:Slc3a2(display_short)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3073|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:NP_001258018.1|interpro:IPR031984|interpro:IPR042280|mint:Q794F9|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|reactome:R-RNO-210991|reactome:R-RNO-352230|reactome:R-RNO-71240	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:gEQnTlE/6x+4eAArJn1IuzL9cJg10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q01177	intact:EBI-1379423	intact:EBI-6122390|uniprotkb:Q5BKB6|uniprotkb:Q9R0W3|ensembl:ENSRNOP00000023370	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:plmn_rat(display_long)|uniprotkb:Plg(gene name)|psi-mi:Plg(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:619893|refseq:NP_445943.1|ensembl:ENSRNOG00000017223(gene)|ensembl:ENSRNOT00000023368(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099183"(trans-synaptic signaling by BDNF, modulating synaptic transmission)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|reactome:R-RNO-114608|reactome:R-RNO-1474228|reactome:R-RNO-1592389|reactome:R-RNO-186797|reactome:R-RNO-381426|reactome:R-RNO-75205|reactome:R-RNO-8964041	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:DDBxYXfF9m4+3SiTLIFbguideKg10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q5U2V4	intact:EBI-1379423	intact:EBI-5747586|ensembl:ENSRNOP00000011930	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:plbl1_rat(display_long)|uniprotkb:Plbd1(gene name)|psi-mi:Plbd1(display_short)|uniprotkb:LAMA-like protein 1(gene name synonym)|uniprotkb:Lamina ancestor homolog 1(gene name synonym)|uniprotkb:Phospholipase B domain-containing protein 1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1308734|refseq:NP_001013949.1|ensembl:ENSRNOG00000008933(gene)|ensembl:ENSRNOT00000011930(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0009395"(phospholipid catabolic process)|interpro:IPR007000(Laminin A)|interpro:IPR043040|interpro:IPR043041|interpro:IPR043042|reactome:R-RNO-1482788|reactome:R-RNO-1482839|reactome:R-RNO-1482922|reactome:R-RNO-1483115	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:UzmnrXsbbeMbpe5D5DmNYgPzj6810116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P15083	intact:EBI-1379423	intact:EBI-15349041	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:pigr_rat(display_long)|uniprotkb:Pigr(gene name)|psi-mi:Pigr(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001792"(polymeric immunoglobulin receptor activity)|go:"GO:0002415"(immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0030133"(transport vesicle)|go:"GO:0038093"(Fc receptor signaling pathway)|go:"GO:0043113"(receptor clustering)|go:"GO:0043235"(receptor complex)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071751"(secretory IgA immunoglobulin complex)|go:"GO:0016021"(integral component of membrane)|reactome:R-RNO-6798695|refseq:NP_036855.3|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|rgd:3328|interpro:IPR036179	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:maSpwAZHNfJvfwEyb4tsmEHH7O410116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P47853	intact:EBI-1379423	intact:EBI-917563|ensembl:ENSRNOP00000072449	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:pgs1_rat(display_long)|uniprotkb:Bone/cartilage proteoglycan I(gene name synonym)|uniprotkb:PG-S1(gene name synonym)|uniprotkb:Bgn(gene name)|psi-mi:Bgn(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2207|refseq:NP_058783.1|ensembl:ENSRNOG00000055962(gene)|ensembl:ENSRNOT00000085201(transcript)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009986"(cell surface)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030133"(transport vesicle)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042383"(sarcolemma)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0060348"(bone development)|go:"GO:0061975"(articular cartilage development)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR016352(Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan)|interpro:IPR028547|interpro:IPR032675|reactome:R-RNO-1971475|reactome:R-RNO-2022870|reactome:R-RNO-2022923|reactome:R-RNO-2024101|reactome:R-RNO-3000178	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:y5uL0GPot1EHpM1UIKRfmWJXdEI10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P31044	intact:EBI-1379423	intact:EBI-15348969|ensembl:ENSRNOP00000001500|uniprotkb:P31045	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:pebp1_rat(display_long)|uniprotkb:Pebp1(gene name)|psi-mi:Pebp1(display_short)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pebp(gene name synonym)|uniprotkb:23 kDa morphine-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:P23K(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000001136(gene)|ensembl:ENSRNOT00000001500(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007286"(spermatid development)|go:"GO:0007568"(aging)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0009611"(response to wounding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014823"(response to activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043679"(axon terminus)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045177"(apical part of cell)|go:"GO:0045471"(response to ethanol)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060409"(positive regulation of acetylcholine metabolic process)|go:"GO:0019899"(enzyme binding)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|rcsb pdb:2IQX|rcsb pdb:2IQY|rcsb pdb:6ENT|reactome:R-RNO-5674135|reactome:R-RNO-5675221|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|refseq:NP_058932.1|rgd:62017	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:4/CzsEquwJQX+5q1YptZK6Qf7yQ10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q63081	intact:EBI-1379423	intact:EBI-918490|uniprotkb:Q641Y3	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:pdia6_rat(display_long)|uniprotkb:Pdia6(gene name)|psi-mi:Pdia6(display_short)|uniprotkb:Cabp1(gene name synonym)|uniprotkb:Txndc7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Calcium-binding protein 1(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:628688|refseq:NP_001004442.1|interpro:IPR005788(Disulphide isomerase)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0030168"(platelet activation)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR044569|interpro:IPR036249|reactome:R-RNO-381426|reactome:R-RNO-8957275	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:WfJSspkQiHrTeuW1AwRqa7Z4ccs10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P21588	intact:EBI-1379423	intact:EBI-15184746	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:5ntd_rat(display_long)|uniprotkb:Nt5e(gene name)|psi-mi:Nt5e(display_short)|uniprotkb:Nt5(gene name synonym)|uniprotkb:Nte(gene name synonym)|uniprotkb:Ecto-5'-nucleotidase(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-RNO-74259|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006196"(AMP catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046032"(ADP catabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046086"(adenosine biosynthetic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0097060"(synaptic membrane)|go:"GO:0007159"(leukocyte cell-cell adhesion)|interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|rgd:61956|interpro:IPR036907|reactome:R-RNO-196807|reactome:R-RNO-73621	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:tv60ppHhbM89bWmz86xyceUKBgc10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q9EPH1	intact:EBI-1379423	intact:EBI-15184809|ensembl:ENSRNOP00000006273|uniprotkb:Q5EBD6|uniprotkb:Q9JKL2	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:a1bg_rat(display_long)|uniprotkb:Alpha-1-B glycoprotein(gene name synonym)|uniprotkb:C44(gene name synonym)|uniprotkb:Liver regeneration-related protein 1(gene name synonym)|uniprotkb:A1bg(gene name)|psi-mi:A1bg(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000004692(gene)|ensembl:ENSRNOT00000006273(transcript)|go:"GO:0005576"(extracellular region)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016332(Alpha-1B-glycoprotein/leukocyte immunoglobulin-like receptor)|interpro:IPR036179|reactome:R-RNO-114608|reactome:R-RNO-6798695|refseq:NP_071594.2|rgd:69417	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:UlRCfAFODBWmhOMmhL/onUC0nkM10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q62975	intact:EBI-1379423	intact:EBI-15349790|ensembl:ENSRNOP00000066602|ensembl:ENSRNOP00000064104|uniprotkb:Q5M8C2	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:zpi_rat(display_long)|uniprotkb:Serpina10(gene name)|psi-mi:Serpina10(display_short)|uniprotkb:Rasp1(gene name synonym)|uniprotkb:Zpi(gene name synonym)|uniprotkb:Regeneration-associated serpin 1(gene name synonym)|uniprotkb:Serpin A10(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000048988(gene)|ensembl:ENSRNOG00000050761(gene)|ensembl:ENSRNOT00000075378(transcript)|rgd:621220|ensembl:ENSRNOT00000073709(transcript)|interpro:IPR000215(Protease inhibitor I4, serpin)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0097421"(liver regeneration)|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|reactome:R-RNO-381426|reactome:R-RNO-8957275|interpro:IPR033835|refseq:NP_598301.2|refseq:XP_003750275.1	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:czZLDG4o/xhRNLlyNHiwN6owe5c10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q62720	intact:EBI-1379423	intact:EBI-15349754|ensembl:ENSRNOP00000006340	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:znt1_rat(display_long)|uniprotkb:Slc30a1(gene name)|psi-mi:Slc30a1(display_short)|uniprotkb:Znt1(gene name synonym)|uniprotkb:Solute carrier family 30 member 1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0010312"(detoxification of zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030315"(T-tubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0070509"(calcium ion import)|go:"GO:0070574"(cadmium ion transmembrane transport)|go:"GO:0071577"(zinc ion transmembrane transport)|ensembl:ENSRNOG00000004749(gene)|ensembl:ENSRNOT00000006340(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071584"(negative regulation of zinc ion transmembrane import)|go:"GO:0071585"(detoxification of cadmium ion)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-RNO-435368|rgd:61918|refseq:NP_074044.1	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:X0alZRT5sdaG9YxUHWj1cpV+eGI10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P04276	intact:EBI-1379423	intact:EBI-15349727	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:vtdb_rat(display_long)|uniprotkb:Gc(gene name)|psi-mi:Gc(display_short)|uniprotkb:Dbp(gene name synonym)|uniprotkb:Gc-globulin(gene name synonym)|uniprotkb:Group-specific component(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0003779"(actin binding)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0030424"(axon)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0090482"(vitamin transmembrane transporter activity)|go:"GO:1902118"(calcidiol binding)|go:"GO:0005829"(cytosol)|rgd:2667|reactome:R-RNO-196791|interpro:IPR000264(Serum albumin)|interpro:IPR020858|interpro:IPR020857|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR000213(Vitamin D-binding protein)|interpro:IPR015247(Vitamin D binding protein, domain III)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:8CzinEO4mO8HE2STg0V+j9pQPwQ10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P02767	intact:EBI-1379423	intact:EBI-6675014|ensembl:ENSRNOP00000022113|uniprotkb:Q547K9	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:tthy_rat(display_long)|uniprotkb:Ttr(gene name)|psi-mi:Ttr(display_short)|uniprotkb:Tt(gene name synonym)|uniprotkb:Prealbumin(gene name synonym)|uniprotkb:TBPA(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000016275(gene)|ensembl:ENSRNOT00000022113(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042403"(thyroid hormone metabolic process)|go:"GO:0042562"(hormone binding)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023418|interpro:IPR023419|interpro:IPR030178|interpro:IPR036817|mint:P02767|rcsb pdb:1GKE|rcsb pdb:1IE4|rcsb pdb:1KGI|rcsb pdb:1KGJ|rcsb pdb:1RVS|rcsb pdb:2M5K|rcsb pdb:2M5M|rcsb pdb:3ZPK|reactome:R-RNO-2453902|reactome:R-RNO-3000171|reactome:R-RNO-6798695|reactome:R-RNO-975634|refseq:XP_006254519.1|refseq:NP_036813.2|rgd:3916	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:36h5MG2Ta1EfNQcgB1d8+GneH4810116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P12346	intact:EBI-1379423	intact:EBI-5748069|uniprotkb:Q63602|uniprotkb:Q64628|uniprotkb:Q64630|uniprotkb:Q7TNX0|ensembl:ENSRNOP00000045637	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:trfe_rat(display_long)|uniprotkb:Tf(gene name)|psi-mi:Tf(display_short)|uniprotkb:Beta-1 metal-binding globulin(gene name synonym)|uniprotkb:Liver regeneration-related protein LRRG03(gene name synonym)|uniprotkb:Siderophilin(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3845|refseq:NP_001013128.1|ensembl:ENSRNOG00000030625(gene)|ensembl:ENSRNOT00000045628(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007015"(actin filament organization)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010288"(response to lead ion)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0031982"(vesicle)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045178"(basal part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051286"(cell tip)|go:"GO:0055037"(recycling endosome)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030685|mint:P12346|reactome:R-RNO-114608|reactome:R-RNO-381426|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8957275|reactome:R-RNO-917937|reactome:R-RNO-917977	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:9b+8HnYQbOkvBtuNUgHzhq2+cQ010116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q8R4E1	intact:EBI-1379423	intact:EBI-15349704	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:tip_rat(display_long)|uniprotkb:Itfg1(gene name)|psi-mi:Itfg1(display_short)|uniprotkb:Cda08(gene name synonym)|uniprotkb:Lnkn-1(gene name synonym)|uniprotkb:Tip(gene name synonym)|uniprotkb:CDA08-like protein(gene name synonym)|uniprotkb:Integrin-alpha FG-GAP repeat-containing protein 1(gene name synonym)|uniprotkb:Linkin(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR028994|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|rgd:619898|interpro:IPR013517(FG-GAP)|interpro:IPR024881	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:/K/kji2K9hPFR4sZhoK2Ss6LaQw10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P18292	intact:EBI-1379423	intact:EBI-15349672	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:thrb_rat(display_long)|uniprotkb:F2(gene name)|psi-mi:F2(display_short)|uniprotkb:Coagulation factor II(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-RNO-381426|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070945"(neutrophil-mediated killing of gram-negative bacterium)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0097068"(response to thyroxine)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900738"(positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1905225"(response to thyrotropin-releasing hormone)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014854"(response to inactivity)|go:"GO:0030168"(platelet activation)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0006953"(acute-phase response)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042730"(fibrinolysis)|rgd:61996|reactome:R-RNO-159782|reactome:R-RNO-202733|reactome:R-RNO-375276|reactome:R-RNO-416476|reactome:R-RNO-456926|reactome:R-RNO-76009|reactome:R-RNO-140875|reactome:R-RNO-159740|reactome:R-RNO-159763|reactome:R-RNO-140837|interpro:IPR035972|interpro:IPR037111|interpro:IPR038178|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000001(Kringle)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003966(Peptidase S1A, prothrombin/thrombin)|interpro:IPR018992|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:+bDrbOIe8wWRzoklFB0M1N1ra+810116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P11232	intact:EBI-1379423	intact:EBI-916302	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:thio_rat(display_long)|uniprotkb:Txn(gene name)|psi-mi:Txn(display_short)|uniprotkb:Txn1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005634"(nucleus)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0048678"(response to axon injury)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071731"(response to nitric oxide)|go:"GO:0097068"(response to thyroxine)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|reactome:R-RNO-2559580|reactome:R-RNO-3299685|reactome:R-RNO-499943|reactome:R-RNO-5628897|reactome:R-RNO-5676934|reactome:R-RNO-844456|go:"GO:0005576"(extracellular region)|go:"GO:0014823"(response to activity)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035690"|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0009314"(response to radiation)|go:"GO:0010269"(response to selenium ion)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|rgd:621157|refseq:NP_446252.1|interpro:IPR005746(Thioredoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|mint:P11232|interpro:IPR036249	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:YEZTjJoaEiTgQe/tyxzrpU+HCVk10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:B2GUY2	intact:EBI-1379423	intact:EBI-15349629|ensembl:ENSRNOP00000001905|ensembl:ENSRNOP00000072585	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:tfr2_rat(display_long)|uniprotkb:Tfr2(gene name)|psi-mi:Tfr2(display_short)|uniprotkb:Trfr2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000001407(gene)|ensembl:ENSRNOT00000001905(transcript)|ensembl:ENSRNOT00000082895(transcript)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006953"(acute-phase response)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033572"(transferrin transport)|go:"GO:0039706"(co-receptor binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0140298"(endocytic iron import into cell)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1990712"(HFE-transferrin receptor complex)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|reactome:R-RNO-917977|go:"GO:0055072"(iron ion homeostasis)|rgd:1310152|refseq:NP_001099386.1|refseq:XP_006249179.1|refseq:XP_006249180.1|refseq:XP_008767347.1|refseq:XP_008767348.1	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:U7RC60PBpxldcqagkqr3VSKaIco10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q99376	intact:EBI-1379423	intact:EBI-2112551|intact:EBI-21232392|uniprotkb:G3V679|ensembl:ENSRNOP00000002407	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:tfr1_rat(display_long)|uniprotkb:Tfrc(gene name)|psi-mi:Tfrc(display_short)|uniprotkb:Trfr(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:70488|refseq:NP_073203.1|refseq:XP_006248524.1|refseq:XP_006248525.1|ensembl:ENSRNOG00000001766(gene)|ensembl:ENSRNOT00000002407(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006953"(acute-phase response)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010033"(response to organic substance)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010039"(response to iron ion)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046688"(response to copper ion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:Q99376|reactome:R-RNO-432722|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013406|reactome:R-RNO-9013407|reactome:R-RNO-9013408|reactome:R-RNO-9013423|reactome:R-RNO-917977|reactome:R-RNO-9696270|reactome:R-RNO-9696273|go:"GO:0016323"(basolateral plasma membrane)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:vqeLiefAr+SqCtwOnGUhDJPpcHo10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P84903	intact:EBI-1379423	intact:EBI-9700551|ensembl:ENSRNOP00000027685	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:stim1_rat(display_long)|uniprotkb:Stim1(gene name)|psi-mi:Stim1(display_short)|uniprotkb:Sim(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1306831|refseq:NP_001101966.2|ensembl:ENSRNOG00000020425(gene)|ensembl:ENSRNOT00000027685(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0014902"(myotube differentiation)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030426"(growth cone)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|reactome:R-RNO-5578775|reactome:R-RNO-983695	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:tFviWTvMIXmKSj4188GoXiMc8HM10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q4V8K1	intact:EBI-1379423	intact:EBI-15349593|ensembl:ENSRNOP00000011432	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:stea4_rat(display_long)|uniprotkb:Steap4(gene name)|psi-mi:Steap4(display_short)|uniprotkb:Six-transmembrane epithelial antigen of prostate 4(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000008602(gene)|go:"GO:0015677"(copper ion import)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033212"(iron import into cell)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052851"("ferric-chelate reductase (NADPH) activity")|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071949"(FAD binding)|go:"GO:0098706"(iron ion import across cell outer membrane)|interpro:IPR013130(Ferric reductase-like transmembrane component, N-terminal)|interpro:IPR028939|interpro:IPR036291|rcsb pdb:2YJZ|ensembl:ENSRNOT00000011432(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0008823"(cupric reductase activity)|go:"GO:0009055"(electron transfer activity)|rgd:1560331|refseq:NP_001037730.1	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:0bCukJQx/YuZMjQ//CacJpusnC410116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q8CFM6	intact:EBI-1379423	intact:EBI-15349565	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:stab2_rat(display_long)|uniprotkb:Stab2(gene name)|psi-mi:Stab2(display_short)|uniprotkb:Feel2(gene name synonym)|uniprotkb:Hare(gene name synonym)|uniprotkb:Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2(gene name synonym)|uniprotkb:Hyaluronan receptor for endocytosis(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|rgd:628822|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR024731|interpro:IPR000782(Beta-Ig-H3/fasciclin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR000538(Link)|interpro:IPR036378	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:3UYGJ3s86FgS3Gk9te3wJA8fp5g10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:O54861	intact:EBI-1379423	intact:EBI-915580|uniprotkb:O35389|ensembl:ENSRNOP00000051102	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:sort_rat(display_long)|uniprotkb:Neurotensin receptor 3(gene name synonym)|uniprotkb:Glycoprotein 110(gene name synonym)|uniprotkb:Sort1(gene name)|psi-mi:Sort1(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:619999|refseq:NP_113955.1|ensembl:ENSRNOG00000031814(gene)|ensembl:ENSRNOT00000049127(transcript)|go:"GO:0001503"(ossification)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010465"(nerve growth factor receptor activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016492"(G protein-coupled neurotensin receptor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030379"(neurotensin receptor activity, non-G protein-coupled)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0046323"(glucose import)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1905394"(retromer complex binding)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|mint:O54861|reactome:R-RNO-432722	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:3DR0ZaBcQurHYvbpi0KIjQZ665010116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q62876	intact:EBI-1379423	intact:EBI-15349536|ensembl:ENSRNOP00000023066	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:sng1_rat(display_long)|uniprotkb:Syngr1(gene name)|psi-mi:Syngr1(display_short)|uniprotkb:p29(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOT00000023066(transcript)|go:"GO:0006605"(protein targeting)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042470"(melanosome)|go:"GO:0043195"(terminal bouton)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|ensembl:ENSRNOG00000017108(gene)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR008253(Marvel)|interpro:IPR016579(Synaptogyrin)|mint:Q62876|reactome:R-RNO-6798695|rgd:3801|refseq:NP_062039.1	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:BLWDXZqURmVydl4j/e8DPDiiuK010116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P13721	intact:EBI-1379423	intact:EBI-15349498|uniprotkb:D4ABR2|uniprotkb:G3V680|ensembl:ENSRNOP00000002496|ensembl:ENSRNOP00000002499|intact:EBI-21295532	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:siat1_rat(display_long)|uniprotkb:St6gal1(gene name)|psi-mi:St6gal1(display_short)|uniprotkb:Siat1(gene name synonym)|uniprotkb:CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1(gene name synonym)|uniprotkb:ST6Gal I(gene name synonym)|uniprotkb:Sialyltransferase 1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_008767014.1|refseq:XP_006248563.1|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0006054"(N-acetylneuraminate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0008373"(sialyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0032946"(positive regulation of mononuclear cell proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045471"(response to ethanol)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0097503"(sialylation)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990743"(protein sialylation)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001675(Glycosyl transferase, family 29)|interpro:IPR012163(Sialyltransferase)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0003835"(beta-galactoside alpha-2,6-sialyltransferase activity)|ensembl:ENSRNOG00000001823(gene)|ensembl:ENSRNOT00000002496(transcript)|ensembl:ENSRNOT00000002499(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|interpro:IPR038578|rcsb pdb:4MPS|reactome:R-RNO-4085001|reactome:R-RNO-975577|reactome:R-RNO-977068|go:"GO:0005576"(extracellular region)|rgd:3676|refseq:NP_001106815.1|refseq:NP_671738.2	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:JKFp/2hdKwvXDAMVXNtyTi7mNz010116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P15389	intact:EBI-1379423	intact:EBI-15349429|uniprotkb:Q925G6	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:scn5a_rat(display_long)|uniprotkb:Scn5a(gene name)|psi-mi:Scn5a(display_short)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034706"(sodium channel complex)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003360"(brainstem development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0051899"(membrane depolarization)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|rcsb pdb:6UZ0|rcsb pdb:6UZ3|rcsb pdb:7K18|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|reactome:R-RNO-5576892|refseq:NP_001153634.1|refseq:NP_037257.1|rgd:3637|dip:DIP-60063N	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:3NfiwYCut6ee8X70Ula5QzpxF5s10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q9JI66	intact:EBI-1379423	intact:EBI-15349394|ensembl:ENSRNOP00000035006|uniprotkb:O35422|uniprotkb:O54815|uniprotkb:Q9JJ32|uniprotkb:Q9QXH6	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:s4a4_rat(display_long)|uniprotkb:Slc4a4(gene name)|psi-mi:Slc4a4(display_short)|uniprotkb:Nbc(gene name synonym)|uniprotkb:Nbc1(gene name synonym)|uniprotkb:Nbce1(gene name synonym)|uniprotkb:Rnbc1(gene name synonym)|uniprotkb:NBC-like protein(gene name synonym)|uniprotkb:"Na(+)/HCO3(-) cotransporter"(gene name synonym)|uniprotkb:Solute carrier family 4 member 4(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000003134(gene)|ensembl:ENSRNOT00000033806(transcript)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0008510"("sodium:bicarbonate symporter activity")|go:"GO:0009986"(cell surface)|go:"GO:0015293"(symporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR003024(Sodium bicarbonate cotransporter)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|go:"GO:0015701"(bicarbonate transport)|mint:Q9JI66|reactome:R-RNO-425381|interpro:IPR016152(Phosphotransferase/anion transporter)|rgd:68936|refseq:NP_445876.1|refseq:XP_006250853.1	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:BrdKn9iXDlKskSzCLKT7rZ+R3JA10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:A0JPN2	intact:EBI-1379423	intact:EBI-15349375	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:s39a4_rat(display_long)|uniprotkb:Slc39a4(gene name)|psi-mi:Slc39a4(display_short)|uniprotkb:Zip4(gene name synonym)|uniprotkb:Solute carrier family 39 member 4(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 4(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034224"(cellular response to zinc ion starvation)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071578"(zinc ion import across plasma membrane)|interpro:IPR041137|reactome:R-RNO-442380|rgd:1306701|refseq:NP_001071137.1|interpro:IPR003689(Zinc/iron permease)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:yFzmPVWoYax/NhXNpg98LgKNkgg10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q9EQ25	intact:EBI-1379423	intact:EBI-15349352|ensembl:ENSRNOP00000009187|ensembl:ENSRNOP00000068616	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:s38a4_rat(display_long)|uniprotkb:Slc38a4(gene name)|psi-mi:Slc38a4(display_short)|uniprotkb:Ata3(gene name synonym)|uniprotkb:Snat4(gene name synonym)|uniprotkb:Amino acid transporter A3(gene name synonym)|uniprotkb:"Na(+)-coupled neutral amino acid transporter 4"(gene name synonym)|uniprotkb:Solute carrier family 38 member 4(gene name synonym)|uniprotkb:System A amino acid transporter 3(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|interpro:IPR013057(Amino acid transporter, transmembrane)|reactome:R-RNO-352230|ensembl:ENSRNOG00000006653(gene)|ensembl:ENSRNOT00000009187(transcript)|ensembl:ENSRNOT00000085620(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|rgd:621836|refseq:NP_570104.1|refseq:XP_008763885.1	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:0f/f660LFohfzGz00cbaqdGjIEU10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q9JHZ9	intact:EBI-1379423	intact:EBI-15349319|ensembl:ENSRNOP00000023623|uniprotkb:Q66HS0	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:s38a3_rat(display_long)|uniprotkb:Slc38a3(gene name)|psi-mi:Slc38a3(display_short)|uniprotkb:Snat3(gene name synonym)|uniprotkb:N-system amino acid transporter 1(gene name synonym)|uniprotkb:"Na(+)-coupled neutral amino acid transporter 3"(gene name synonym)|uniprotkb:Solute carrier family 38 member 3(gene name synonym)|uniprotkb:System N amino acid transporter 1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000016827(gene)|ensembl:ENSRNOT00000023623(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006867"(asparagine transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015182"(L-asparagine transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0061402"(positive regulation of transcription from RNA polymerase II promoter in response to acidic pH)|go:"GO:2000487"(positive regulation of glutamine transport)|interpro:IPR013057(Amino acid transporter, transmembrane)|reactome:R-RNO-352230|go:"GO:0015808"(L-alanine transport)|rgd:628620|refseq:NP_665719.1	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:h/w0+xZcBw0HldebdPI9M6XpDzE10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q6AY78	intact:EBI-1379423	intact:EBI-15349300	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:s22ai_rat(display_long)|uniprotkb:Slc22a18(gene name)|psi-mi:Slc22a18(display_short)|uniprotkb:Orctl2(gene name synonym)|uniprotkb:Tssc5(gene name synonym)|uniprotkb:Organic cation transporter-like protein 2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0006811"(ion transport)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|reactome:R-RNO-549127|rgd:1303323|refseq:NP_001004260.1|refseq:XP_006230837.1|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR001958(Tetracycline resistance protein, TetA)|interpro:IPR036259	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:3WlI2VWQW7ywVnDHfAihgls2i6U10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q5RLM2	intact:EBI-1379423	intact:EBI-15349274|ensembl:ENSRNOP00000025094|uniprotkb:Q63314	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:s22a7_rat(display_long)|uniprotkb:Slc22a7(gene name)|psi-mi:Slc22a7(display_short)|uniprotkb:Nlt(gene name synonym)|uniprotkb:Oat2(gene name synonym)|uniprotkb:Novel liver transporter(gene name synonym)|uniprotkb:Organic anion transporter 2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000018420(gene)|ensembl:ENSRNOT00000025094(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0035634"(response to stilbenoid)|interpro:IPR004749(Organic cation transport protein)|interpro:IPR005828(General substrate transporter)|interpro:IPR020846|interpro:IPR036259|reactome:R-RNO-561048|rgd:621699|refseq:NP_445989.2	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:t6AjMRJDadOeNV82gFhx8BpSfgw10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q63089	intact:EBI-1379423	intact:EBI-5261153|uniprotkb:O35882|uniprotkb:Q6AYW1|ensembl:ENSRNOP00000022254	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:s22a1_rat(display_long)|uniprotkb:Slc22a1(gene name)|psi-mi:Slc22a1(display_short)|uniprotkb:Oct1(gene name synonym)|uniprotkb:Organic cation transporter 1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3224|refseq:NP_036829.1|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0048241"(epinephrine transport)|go:"GO:0051610"(serotonin uptake)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0098793"(presynapse)|go:"GO:1901998"(toxin transport)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR004749(Organic cation transport protein)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-RNO-112311|reactome:R-RNO-181430|reactome:R-RNO-2161517|reactome:R-RNO-442660|reactome:R-RNO-549127|ensembl:ENSRNOT00000022254(transcript)|go:"GO:0005277"(acetylcholine transmembrane transporter activity)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0008513"(secondary active organic cation transmembrane transporter activity)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0015101"(organic cation transmembrane transporter activity)|go:"GO:0015214"(pyrimidine nucleoside transmembrane transporter activity)|go:"GO:0015651"(quaternary ammonium group transmembrane transporter activity)|go:"GO:0015695"(organic cation transport)|go:"GO:0015697"(quaternary ammonium group transport)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019534"(toxin transmembrane transporter activity)|ensembl:ENSRNOG00000016337(gene)	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:/NgjkDrW7r8CgPD34UOBfBfKG0A10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q63488	intact:EBI-1379423	intact:EBI-15349243|ensembl:ENSRNOP00000026418	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:s20a2_rat(display_long)|uniprotkb:Slc20a2(gene name)|psi-mi:Slc20a2(display_short)|uniprotkb:Pit2(gene name synonym)|uniprotkb:Ram1(gene name synonym)|uniprotkb:Phosphate transporter 2(gene name synonym)|uniprotkb:Receptor for amphotropic viruses 1(gene name synonym)|uniprotkb:Solute carrier family 20 member 2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|interpro:IPR001204(Phosphate transporter)|reactome:R-RNO-427652|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|ensembl:ENSRNOG00000019490(gene)|ensembl:ENSRNOT00000026418(transcript)|refseq:NP_058919.1|refseq:XP_008769573.1|refseq:XP_008769574.1|refseq:XP_017455543.1|rgd:3699	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:/QuI9IJ2tCwPkiUQ04X78+V6olQ10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q66HR0	intact:EBI-1379423	intact:EBI-15349225|uniprotkb:Q99NC8	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:s12a9_rat(display_long)|uniprotkb:Slc12a9(gene name)|psi-mi:Slc12a9(display_short)|uniprotkb:Ccc6(gene name synonym)|uniprotkb:Cation-chloride cotransporter 6(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005886"(plasma membrane)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|mint:Q66HR0|refseq:NP_599232.1|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR018491|interpro:IPR030345|rgd:620747	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:YAXuIzstPgFUU4o5zrgujLowsTk10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P38983	intact:EBI-1379423	intact:EBI-917451|uniprotkb:B6ZB78|ensembl:ENSRNOP00000025224	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:rssa_rat(display_long)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:71026|refseq:NP_058834.1|ensembl:ENSRNOG00000018645(gene)|ensembl:ENSRNOT00000025225(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P38983|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:XVgtLKyvO/UwRSx+OqV7+lc98XI10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:O88397	intact:EBI-1379423	intact:EBI-15349182|ensembl:ENSRNOP00000048288|uniprotkb:Q9EQR8	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:so1a5_rat(display_long)|uniprotkb:Slco1a5(gene name)|psi-mi:Slco1a5(display_short)|uniprotkb:Oatp1a5(gene name synonym)|uniprotkb:Oatp3(gene name synonym)|uniprotkb:Slc21a7(gene name synonym)|uniprotkb:Slco1a2(gene name synonym)|uniprotkb:Organic anion-transporting polypeptide 3(gene name synonym)|uniprotkb:Sodium-independent organic anion transporter 3(gene name synonym)|uniprotkb:Solute carrier family 21 member 7(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000031249(gene)|ensembl:ENSRNOT00000049569(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015347"(sodium-independent organic anion transmembrane transporter activity)|go:"GO:0015349"(thyroid hormone transmembrane transporter activity)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0015711"(organic anion transport)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0031526"(brush border membrane)|go:"GO:0043252"(sodium-independent organic anion transport)|go:"GO:0050892"(intestinal absorption)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR004156(Organic anion transporter polypeptide OATP)|interpro:IPR020846|interpro:IPR036058|interpro:IPR036259|refseq:NP_110465.1|refseq:XP_006237704.1|refseq:XP_006237705.1|refseq:XP_006237708.1|refseq:XP_008761654.1|refseq:XP_017448393.1|refseq:XP_017448394.1|rgd:70985	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:3+OJJVEUf1Diws6i5NOl9KV2reU10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P97887	intact:EBI-1379423	intact:EBI-2878956|uniprotkb:P97529|ensembl:ENSRNOP00000012495	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:psn1_rat(display_long)|uniprotkb:Psen1(gene name)|psi-mi:Psen1(display_short)|uniprotkb:Psnl1(gene name synonym)|uniprotkb:Protein S182(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3425|refseq:NP_062036.2|ensembl:ENSRNOG00000009110(gene)|ensembl:ENSRNOT00000012495(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000776"(kinetochore)|go:"GO:0001568"(blood vessel development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0001764"(neuron migration)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0003407"(neural retina development)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006486"(protein glycosylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008233"(peptidase activity)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0015871"(choline transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016485"(protein processing)|go:"GO:0021549"(cerebellum development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021870"(Cajal-Retzius cell differentiation)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0030425"(dendrite)|go:"GO:0040011"(locomotion)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042500"(aspartic endopeptidase activity, intramembrane cleaving)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043198"(dendritic shaft)|go:"GO:0030426"(growth cone)|go:"GO:0030900"(forebrain development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048666"(neuron development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050820"(positive regulation of coagulation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051563"(smooth endoplasmic reticulum calcium ion homeostasis)|go:"GO:0051604"(protein maturation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904797"(negative regulation of core promoter binding)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001108(Peptidase A22A, presenilin)|interpro:IPR002031(Peptidase A22A, presenilin 1)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR042524|reactome:R-RNO-1251985|reactome:R-RNO-193692|reactome:R-RNO-205043|reactome:R-RNO-3928665|reactome:R-RNO-6798695|reactome:R-RNO-9013507|reactome:R-RNO-9017802|refseq:XP_006240383.1|refseq:XP_006240384.1|dip:DIP-48909N	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:wbqH7EhhFtBBiLnQdS/NW23xYfQ10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q9Z0V5	intact:EBI-1379423	intact:EBI-920242|ensembl:ENSRNOP00000005014	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:prdx4_rat(display_long)|uniprotkb:Prdx4(gene name)|psi-mi:Prdx4(display_short)|uniprotkb:Rno2CysPrx04(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:620043|refseq:NP_445964.1|ensembl:ENSRNOG00000003763(gene)|ensembl:ENSRNOT00000005014(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|reactome:R-RNO-6798695	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:3Oi90941+tXQ+wCOleurOvI0GAs10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q68FP2	intact:EBI-1379423	intact:EBI-15349140|ensembl:ENSRNOP00000012050	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:pon3_rat(display_long)|uniprotkb:Pon3(gene name)|psi-mi:Pon3(display_short)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000009096(gene)|go:"GO:0004063"(aryldialkylphosphatase activity)|go:"GO:0004064"(arylesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010124"(phenylacetate catabolic process)|go:"GO:0018733"(3,4-dihydrocoumarin hydrolase activity)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046226"(coumarin catabolic process)|go:"GO:0046395"(carboxylic acid catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0102007"(acyl-L-homoserine-lactone lactonohydrolase activity)|interpro:IPR002640(Arylesterase)|interpro:IPR008364(Paraoxonase2)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|reactome:R-RNO-2142688|ensembl:ENSRNOT00000012050(transcript)|refseq:NP_001004086.1|rgd:1302965	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:osv38lr14mez7QDGyrQXTzCN4UE10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:Q6AXM8	intact:EBI-1379423	intact:EBI-15349111|ensembl:ENSRNOP00000033943	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:pon2_rat(display_long)|uniprotkb:Pon2(gene name)|psi-mi:Pon2(display_short)|uniprotkb:Aromatic esterase 2(gene name synonym)|uniprotkb:Serum aryldialkylphosphatase 2(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSRNOG00000009112(gene)|ensembl:ENSRNOT00000036460(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009636"(response to toxic substance)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0102007"(acyl-L-homoserine-lactone lactonohydrolase activity)|interpro:IPR002640(Arylesterase)|interpro:IPR008364(Paraoxonase2)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|reactome:R-RNO-2142688|refseq:NP_001013100.1|rgd:1309954	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:KlcHgTx2tTTd5wNOqyJokG5TFKg10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:28304"	uniprotkb:P55159	intact:EBI-1379423	intact:EBI-15349068|ensembl:ENSRNOP00000011823|uniprotkb:O08682|uniprotkb:Q5BJN6	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:pon1_rat(display_long)|uniprotkb:Pon1(gene name)|psi-mi:Pon1(display_short)|uniprotkb:Pon(gene name synonym)|uniprotkb:Aromatic esterase 1(gene name synonym)|uniprotkb:Serum aryldialkylphosphatase 1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Ori et al. (2011)	pubmed:21454685|imex:IM-25784	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-15184828|imex:IM-25784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-RNO-2142688|ensembl:ENSRNOG00000008902(gene)|ensembl:ENSRNOT00000011823(transcript)|go:"GO:0004063"(aryldialkylphosphatase activity)|go:"GO:0004064"(arylesterase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046395"(carboxylic acid catabolic process)|go:"GO:0046434"(organophosphate catabolic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0102007"(acyl-L-homoserine-lactone lactonohydrolase activity)|go:"GO:1902617"(response to fluoride)|interpro:IPR002640(Arylesterase)|interpro:IPR008363(Paraoxonase1)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|go:"GO:0009636"(response to toxic substance)|refseq:NP_114466.1|rgd:620062	-	-	-	figure legend:Supplemental Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/22	2020/12/11	-	rogid:Ig19wfboYYaSGJSmRRT6gwWSqDs10116	-	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)