#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P58301 uniprotkb:P58301 intact:EBI-2505704|ensemblbacteria:AAL81291 intact:EBI-2505704|ensemblbacteria:AAL81291 psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:"MI:0096"(pull down) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15917083|imex:IM-16097-1|dip:DIP-186991E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E false binding-associated region:1-195|his tag:c-c binding-associated region:704-882 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P58301 uniprotkb:Q8U1N9 intact:EBI-2505704|ensemblbacteria:AAL81291 intact:EBI-2014945|ensemblbacteria:AAL81290 psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name) psi-mi:"MI:0096"(pull down) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15917083|imex:IM-16097-1|dip:DIP-186991E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497 rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E false binding-associated region:1-195|his tag:c-c sufficient binding region:348-426 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P58301 uniprotkb:Q8U1N9 intact:EBI-2505704|ensemblbacteria:AAL81291 intact:EBI-2014945|ensemblbacteria:AAL81290 psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15917155|imex:IM-16097-4|dip:DIP-186991E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497 rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E false binding-associated region:1-195|binding-associated region:704-882 binding-associated region:348-381 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58301 uniprotkb:Q8U1N9 intact:EBI-2505704|ensemblbacteria:AAL81291 intact:EBI-2014945|ensemblbacteria:AAL81290 psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name) psi-mi:"MI:0071"(molecular sieving) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15917132|imex:IM-16097-3|dip:DIP-186991E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497 rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E false binding-associated region:1-195|binding-associated region:704-882 binding-associated region:348-381 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58301 uniprotkb:Q8U1N9 intact:EBI-2505704|ensemblbacteria:AAL81291 intact:EBI-2014945|ensemblbacteria:AAL81290 psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name) psi-mi:"MI:0114"(x-ray crystallography) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15917110|imex:IM-16097-2|dip:DIP-186991E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497 rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E false binding-associated region:716-882,1-187 binding-associated region:348-381 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58301 uniprotkb:Q8U1N9 intact:EBI-2505704|ensemblbacteria:AAL81291 intact:EBI-2014945|ensemblbacteria:AAL81290 psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name) psi-mi:"MI:0071"(molecular sieving) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15917178|imex:IM-16097-5|dip:DIP-186991E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497 rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E false binding-associated region:1-187,716-882 binding-associated region:348-381 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q09683 uniprotkb:Q09683 intact:EBI-2124866|ensemblfungi:"SPAC13C5.07.1:pep" intact:EBI-2124866|ensemblfungi:"SPAC13C5.07.1:pep" psi-mi:rad32_schpo(display_long)|uniprotkb:rad32(gene name)|psi-mi:rad32(display_short)|uniprotkb:SPAC13C5.07(orf name) psi-mi:rad32_schpo(display_long)|uniprotkb:rad32(gene name)|psi-mi:rad32(display_short)|uniprotkb:SPAC13C5.07(orf name) psi-mi:"MI:0018"(two hybrid) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15917200|imex:IM-16097-6|dip:DIP-132479E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_592935.1|reactome:R-SPO-1834949|reactome:R-SPO-2559586|reactome:R-SPO-5693548|reactome:R-SPO-5693565|dip:DIP-52388N|reactome:R-SPO-5685939|ensemblfungi:SPAC13C5.07(gene)|ensemblfungi:SPAC13C5.07.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0004518"(nuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW|rcsb pdb:4FCX refseq:NP_592935.1|reactome:R-SPO-1834949|reactome:R-SPO-2559586|reactome:R-SPO-5693548|reactome:R-SPO-5693565|dip:DIP-52388N|reactome:R-SPO-5685939|ensemblfungi:SPAC13C5.07(gene)|ensemblfungi:SPAC13C5.07.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0004518"(nuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW|rcsb pdb:4FCX psi-mi:"MI:0465"(dip) crc64:400B349EF4FA3428 crc64:400B349EF4FA3428 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2017/08/07 2017/08/10 rogid:FILmnrrlrq43tN0J4RzclGn79Ho284812 rogid:FILmnrrlrq43tN0J4RzclGn79Ho284812 rigid:0/5g+MG0xYj60LYNI+TzrK57SHY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43070 uniprotkb:Q09683 intact:EBI-2125045|uniprotkb:Q86ZQ0|ensemblfungi:"SPBC6B1.09c.1:pep" intact:EBI-2124866|ensemblfungi:"SPAC13C5.07.1:pep" psi-mi:nbs1_schpo(display_long)|uniprotkb:nbs1(gene name)|psi-mi:nbs1(display_short)|uniprotkb:SPBC6B1.09c(orf name) psi-mi:rad32_schpo(display_long)|uniprotkb:rad32(gene name)|psi-mi:rad32(display_short)|uniprotkb:SPAC13C5.07(orf name) psi-mi:"MI:0018"(two hybrid) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15917217|imex:IM-16097-7|dip:DIP-132477E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018823.1|dip:DIP-52387N|reactome:R-SPO-2559586|reactome:R-SPO-5685939|reactome:R-SPO-5693548|reactome:R-SPO-5693565|ensemblfungi:SPBC6B1.09c(gene)|ensemblfungi:SPBC6B1.09c.1(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990166"(protein localization to site of double-strand break)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|interpro:IPR040227|rcsb pdb:3HUE|rcsb pdb:3HUF|rcsb pdb:3I0M|rcsb pdb:3I0N|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW refseq:NP_592935.1|reactome:R-SPO-1834949|reactome:R-SPO-2559586|reactome:R-SPO-5693548|reactome:R-SPO-5693565|dip:DIP-52388N|reactome:R-SPO-5685939|ensemblfungi:SPAC13C5.07(gene)|ensemblfungi:SPAC13C5.07.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0004518"(nuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW|rcsb pdb:4FCX psi-mi:"MI:0465"(dip) crc64:B3384CCC85F96DD1 crc64:400B349EF4FA3428 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2017/08/07 2017/08/10 rogid:5h/qx0stPyVRQ9vtqO50Ftq0mvM284812 rogid:FILmnrrlrq43tN0J4RzclGn79Ho284812 rigid:Utj9gdoZI/D5hITpWFf2sUUAaHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UTJ8 uniprotkb:Q09683 intact:EBI-2125086|uniprotkb:Q9P3T5|ensemblfungi:"SPAC1556.01c.1:pep" intact:EBI-2124866|ensemblfungi:"SPAC13C5.07.1:pep" psi-mi:rad50_schpo(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:SPAC1556.01c(orf name)|uniprotkb:SPAP4C9.01c(orf name) psi-mi:rad32_schpo(display_long)|uniprotkb:rad32(gene name)|psi-mi:rad32(display_short)|uniprotkb:SPAC13C5.07(orf name) psi-mi:"MI:0018"(two hybrid) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15917306|imex:IM-16097-11|dip:DIP-132478E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_001713090.2|reactome:R-SPO-2559586|reactome:R-SPO-5693548|reactome:R-SPO-5693565|dip:DIP-52389N|reactome:R-SPO-5685939|ensemblfungi:SPAC1556.01c(gene)|ensemblfungi:SPAC1556.01c.1(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|go:"GO:0120290"(stalled replication fork localization to nuclear periphery)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903211"(mitotic recombination involved in replication fork processing)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR004584(Recombination/repair protein Rad50)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729 refseq:NP_592935.1|reactome:R-SPO-1834949|reactome:R-SPO-2559586|reactome:R-SPO-5693548|reactome:R-SPO-5693565|dip:DIP-52388N|reactome:R-SPO-5685939|ensemblfungi:SPAC13C5.07(gene)|ensemblfungi:SPAC13C5.07.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0004518"(nuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW|rcsb pdb:4FCX psi-mi:"MI:0465"(dip) crc64:DF45B2EAE7097295 crc64:400B349EF4FA3428 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2017/08/07 2017/08/10 rogid:/h3u58m3i+rCJljt36veVoFiYFE284812 rogid:FILmnrrlrq43tN0J4RzclGn79Ho284812 rigid:JjtUlm+nUFoQMpIq89FQc6SsBbo false - mutation disrupting interaction:455-455,454-454|mutation disrupting interaction:480-480,479-479|mutation disrupting interaction:480-480,479-479,455-455,454-454 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58301 uniprotkb:Q8U1N9 intact:EBI-2505704|ensemblbacteria:AAL81291 intact:EBI-2014945|ensemblbacteria:AAL81290 psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name) psi-mi:"MI:0826"(x ray scattering) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15917283|imex:IM-16097-10|dip:DIP-186991E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497 rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E false binding-associated region:1-195|binding-associated region:704-882 binding-associated region:348-381 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58301 uniprotkb:Q8U1N9 intact:EBI-2505704|ensemblbacteria:AAL81291 intact:EBI-2014945|ensemblbacteria:AAL81290 psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name) psi-mi:"MI:0096"(pull down) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15917259|imex:IM-16097-9|dip:DIP-186991E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497 rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E false binding-associated region:716-882,1-187 sufficient binding region:348-381|his tag:n-n - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P58301 uniprotkb:Q8U1N9 intact:EBI-2505704|ensemblbacteria:AAL81291 intact:EBI-2014945|ensemblbacteria:AAL81290 psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name) psi-mi:"MI:0114"(x-ray crystallography) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15917236|imex:IM-16097-8|dip:DIP-186991E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497 rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E false binding-associated region:1-195|binding-associated region:704-882 binding-associated region:348-381 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58301 uniprotkb:Q8U1N9 intact:EBI-2505704|ensemblbacteria:AAL81291 intact:EBI-2014945|ensemblbacteria:AAL81290 psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Williams et al. (2011) pubmed:21441914|doi:10.1038/nsmb.2038|imex:IM-16097 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15917337|imex:IM-16097-12|dip:DIP-186991E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497 rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E false binding-associated region:716-882,1-187 binding-associated region:348-381 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)