#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12315 uniprotkb:P20449 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W intact:EBI-5617|uniprotkb:D6W2B2|ensemblfungi:YOR046C psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:dbp5_yeast(display_long)|uniprotkb:YOR046C(locus name)|uniprotkb:DBP5(gene name)|psi-mi:DBP5(display_short)|uniprotkb:RAT8(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:Helicase CA5/6(gene name synonym)|uniprotkb:Ribonucleic acid-trafficking protein 8(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Montpetit et al. (2011) pubmed:21441902|doi:10.1038/nature09862|imex:IM-16224 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15916655|imex:IM-16224-1|dip:DIP-2738E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E refseq:NP_014689.1|sgd:S000005572|dip:DIP-2352N|mint:P20449|ensemblfungi:YOR046C(gene)|ensemblfungi:YOR046C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006415"(translational termination)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2KBE|rcsb pdb:2KBF|rcsb pdb:3GFP|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3PEW|rcsb pdb:3PEY|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:5ELX psi-mi:"MI:0465"(dip) crc64:C9C6B1513AF95711 crc64:C50CAFE8C060D46B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rogid:54iW7iCC7GTFWfgoHUq0Qv5WVMI559292 rigid:fb4bXGBt/gxGTNUo9Eq2l5VBzzw false binding-associated region:244-538 sufficient binding region:303-482 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12315 uniprotkb:P20449 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W intact:EBI-5617|uniprotkb:D6W2B2|ensemblfungi:YOR046C psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:dbp5_yeast(display_long)|uniprotkb:YOR046C(locus name)|uniprotkb:DBP5(gene name)|psi-mi:DBP5(display_short)|uniprotkb:RAT8(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:Helicase CA5/6(gene name synonym)|uniprotkb:Ribonucleic acid-trafficking protein 8(gene name synonym) psi-mi:"MI:0880"(atpase assay) Montpetit et al. (2011) pubmed:21441902|doi:10.1038/nature09862|imex:IM-16224 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15916676|imex:IM-16224-2|dip:DIP-2738E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E refseq:NP_014689.1|sgd:S000005572|dip:DIP-2352N|mint:P20449|ensemblfungi:YOR046C(gene)|ensemblfungi:YOR046C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006415"(translational termination)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2KBE|rcsb pdb:2KBF|rcsb pdb:3GFP|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3PEW|rcsb pdb:3PEY|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:5ELX psi-mi:"MI:0465"(dip) crc64:C9C6B1513AF95711 crc64:C50CAFE8C060D46B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rogid:54iW7iCC7GTFWfgoHUq0Qv5WVMI559292 rigid:fb4bXGBt/gxGTNUo9Eq2l5VBzzw false mutation disrupting interaction:520-520,516-516,513-513 sufficient binding region:91-482 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12315 uniprotkb:P20449 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W intact:EBI-5617|uniprotkb:D6W2B2|ensemblfungi:YOR046C psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:dbp5_yeast(display_long)|uniprotkb:YOR046C(locus name)|uniprotkb:DBP5(gene name)|psi-mi:DBP5(display_short)|uniprotkb:RAT8(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:Helicase CA5/6(gene name synonym)|uniprotkb:Ribonucleic acid-trafficking protein 8(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Montpetit et al. (2011) pubmed:21441902|doi:10.1038/nature09862|imex:IM-16224 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15916749|imex:IM-16224-5|dip:DIP-2738E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E refseq:NP_014689.1|sgd:S000005572|dip:DIP-2352N|mint:P20449|ensemblfungi:YOR046C(gene)|ensemblfungi:YOR046C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006415"(translational termination)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2KBE|rcsb pdb:2KBF|rcsb pdb:3GFP|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3PEW|rcsb pdb:3PEY|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:5ELX psi-mi:"MI:0465"(dip) crc64:C9C6B1513AF95711 crc64:C50CAFE8C060D46B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rogid:54iW7iCC7GTFWfgoHUq0Qv5WVMI559292 rigid:fb4bXGBt/gxGTNUo9Eq2l5VBzzw false binding-associated region:244-538 sufficient binding region:303-482 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20449 uniprotkb:Q12315 intact:EBI-5617|uniprotkb:D6W2B2|ensemblfungi:YOR046C intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W psi-mi:dbp5_yeast(display_long)|uniprotkb:YOR046C(locus name)|uniprotkb:DBP5(gene name)|psi-mi:DBP5(display_short)|uniprotkb:RAT8(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:Helicase CA5/6(gene name synonym)|uniprotkb:Ribonucleic acid-trafficking protein 8(gene name synonym) psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Montpetit et al. (2011) pubmed:21441902|doi:10.1038/nature09862|imex:IM-16224 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15916725|imex:IM-16224-4|dip:DIP-187265E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014689.1|sgd:S000005572|dip:DIP-2352N|mint:P20449|ensemblfungi:YOR046C(gene)|ensemblfungi:YOR046C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006415"(translational termination)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2KBE|rcsb pdb:2KBF|rcsb pdb:3GFP|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3PEW|rcsb pdb:3PEY|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:5ELX sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E psi-mi:"MI:0465"(dip) crc64:C50CAFE8C060D46B crc64:C9C6B1513AF95711 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:54iW7iCC7GTFWfgoHUq0Qv5WVMI559292 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rigid:2gBhqm0JcOhyBpZ+vDlsVIddMmw false binding-associated region:91-482 binding-associated region:244-538 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20449 uniprotkb:P40477 intact:EBI-5617|uniprotkb:D6W2B2|ensemblfungi:YOR046C intact:EBI-11747|ensemblfungi:YIL115C|uniprotkb:D6VVH2 psi-mi:dbp5_yeast(display_long)|uniprotkb:YOR046C(locus name)|uniprotkb:DBP5(gene name)|psi-mi:DBP5(display_short)|uniprotkb:RAT8(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:Helicase CA5/6(gene name synonym)|uniprotkb:Ribonucleic acid-trafficking protein 8(gene name synonym) psi-mi:nu159_yeast(display_long)|uniprotkb:NUP158(gene name synonym)|uniprotkb:YIL115C(locus name)|uniprotkb:NUP159(gene name)|psi-mi:NUP159(display_short)|uniprotkb:RAT7(gene name synonym)|uniprotkb:Nuclear pore protein NUP159(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Montpetit et al. (2011) pubmed:21441902|doi:10.1038/nature09862|imex:IM-16224 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15916725|imex:IM-16224-4|dip:DIP-187265E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014689.1|sgd:S000005572|dip:DIP-2352N|mint:P20449|ensemblfungi:YOR046C(gene)|ensemblfungi:YOR046C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006415"(translational termination)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2KBE|rcsb pdb:2KBF|rcsb pdb:3GFP|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3PEW|rcsb pdb:3PEY|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:5ELX ensemblfungi:YIL115C(gene)|ensemblfungi:YIL115C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0061912"(selective autophagy)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR039462|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|rcsb pdb:1XIP|rcsb pdb:3PBP|rcsb pdb:3RRM|rcsb pdb:3TKN|rcsb pdb:4DS1|refseq:NP_012151.1|sgd:S000001377|mint:P40477|dip:DIP-2314N psi-mi:"MI:0465"(dip) crc64:C50CAFE8C060D46B crc64:A33FFA52378F8205 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:54iW7iCC7GTFWfgoHUq0Qv5WVMI559292 rogid:zoNwE4GaFG+YrQQO/qgaq9iHky8559292 rigid:2gBhqm0JcOhyBpZ+vDlsVIddMmw false binding-associated region:91-482 binding-associated region:2-387 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20449 uniprotkb:Q12315 intact:EBI-5617|uniprotkb:D6W2B2|ensemblfungi:YOR046C intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W psi-mi:dbp5_yeast(display_long)|uniprotkb:YOR046C(locus name)|uniprotkb:DBP5(gene name)|psi-mi:DBP5(display_short)|uniprotkb:RAT8(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:Helicase CA5/6(gene name synonym)|uniprotkb:Ribonucleic acid-trafficking protein 8(gene name synonym) psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Montpetit et al. (2011) pubmed:21441902|doi:10.1038/nature09862|imex:IM-16224 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15916700|imex:IM-16224-3|dip:DIP-187265E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014689.1|sgd:S000005572|dip:DIP-2352N|mint:P20449|ensemblfungi:YOR046C(gene)|ensemblfungi:YOR046C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006415"(translational termination)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2KBE|rcsb pdb:2KBF|rcsb pdb:3GFP|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3PEW|rcsb pdb:3PEY|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:5ELX sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E psi-mi:"MI:0465"(dip) crc64:C50CAFE8C060D46B crc64:C9C6B1513AF95711 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:54iW7iCC7GTFWfgoHUq0Qv5WVMI559292 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rigid:2gBhqm0JcOhyBpZ+vDlsVIddMmw false binding-associated region:91-482 binding-associated region:244-538 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20449 uniprotkb:P40477 intact:EBI-5617|uniprotkb:D6W2B2|ensemblfungi:YOR046C intact:EBI-11747|ensemblfungi:YIL115C|uniprotkb:D6VVH2 psi-mi:dbp5_yeast(display_long)|uniprotkb:YOR046C(locus name)|uniprotkb:DBP5(gene name)|psi-mi:DBP5(display_short)|uniprotkb:RAT8(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:Helicase CA5/6(gene name synonym)|uniprotkb:Ribonucleic acid-trafficking protein 8(gene name synonym) psi-mi:nu159_yeast(display_long)|uniprotkb:NUP158(gene name synonym)|uniprotkb:YIL115C(locus name)|uniprotkb:NUP159(gene name)|psi-mi:NUP159(display_short)|uniprotkb:RAT7(gene name synonym)|uniprotkb:Nuclear pore protein NUP159(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Montpetit et al. (2011) pubmed:21441902|doi:10.1038/nature09862|imex:IM-16224 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15916700|imex:IM-16224-3|dip:DIP-187265E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014689.1|sgd:S000005572|dip:DIP-2352N|mint:P20449|ensemblfungi:YOR046C(gene)|ensemblfungi:YOR046C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006415"(translational termination)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2KBE|rcsb pdb:2KBF|rcsb pdb:3GFP|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3PEW|rcsb pdb:3PEY|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:5ELX ensemblfungi:YIL115C(gene)|ensemblfungi:YIL115C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0061912"(selective autophagy)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR039462|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|rcsb pdb:1XIP|rcsb pdb:3PBP|rcsb pdb:3RRM|rcsb pdb:3TKN|rcsb pdb:4DS1|refseq:NP_012151.1|sgd:S000001377|mint:P40477|dip:DIP-2314N psi-mi:"MI:0465"(dip) crc64:C50CAFE8C060D46B crc64:A33FFA52378F8205 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:54iW7iCC7GTFWfgoHUq0Qv5WVMI559292 rogid:zoNwE4GaFG+YrQQO/qgaq9iHky8559292 rigid:2gBhqm0JcOhyBpZ+vDlsVIddMmw false binding-associated region:91-482 binding-associated region:2-387 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12315 uniprotkb:P20449 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W intact:EBI-5617|uniprotkb:D6W2B2|ensemblfungi:YOR046C psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:dbp5_yeast(display_long)|uniprotkb:YOR046C(locus name)|uniprotkb:DBP5(gene name)|psi-mi:DBP5(display_short)|uniprotkb:RAT8(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:Helicase CA5/6(gene name synonym)|uniprotkb:Ribonucleic acid-trafficking protein 8(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Montpetit et al. (2011) pubmed:21441902|doi:10.1038/nature09862|imex:IM-16224 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15916770|imex:IM-16224-6|dip:DIP-2738E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E refseq:NP_014689.1|sgd:S000005572|dip:DIP-2352N|mint:P20449|ensemblfungi:YOR046C(gene)|ensemblfungi:YOR046C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006415"(translational termination)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2KBE|rcsb pdb:2KBF|rcsb pdb:3GFP|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3PEW|rcsb pdb:3PEY|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:5ELX psi-mi:"MI:0465"(dip) crc64:C9C6B1513AF95711 crc64:C50CAFE8C060D46B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rogid:54iW7iCC7GTFWfgoHUq0Qv5WVMI559292 rigid:fb4bXGBt/gxGTNUo9Eq2l5VBzzw false mutation:337-337 mutation disrupting interaction:477-477,327-327,481-481 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)