#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q68D85	uniprotkb:O14931	intact:EBI-14061804|uniprotkb:Q7Z3M6|ensembl:ENSP00000341637|ensembl:ENSP00000434394	intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3	psi-mi:nr3l1_human(display_long)|uniprotkb:NCR3LG1(gene name)|psi-mi:NCR3LG1(display_short)|uniprotkb:B7 homolog 6(gene name synonym)|uniprotkb:B7H6(gene name synonym)	psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Li et al. (2011)	pubmed:21422170|imex:IM-25751	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14989247|imex:IM-25751-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189368.1|ensembl:ENSG00000188211(gene)|ensembl:ENST00000338965(transcript)|ensembl:ENST00000530403(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR036946|rcsb pdb:3PV6|rcsb pdb:3PV7|rcsb pdb:4ZSO|rcsb pdb:6YJP|reactome:R-HSA-198933|dip:DIP-59940N	ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N	-	-	-	figure legend:Table 1|3d-resolution:2.5A|3d-r-factors:R work= 23.9  R Free= 28.9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/05/05	2017/05/25	rogid:zxyF+bJz/qWtsilosYWPqwnDUw89606	rogid:bS3R8rfddez5+tROQijf3FtslOU9606	rigid:RGs60g1CS7VjnF4PJeDm9zXbysI	false	sufficient binding region:25-262(IPR013783)|his tag:c-c	sufficient binding region:19-135(IPR013783)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q68D85	uniprotkb:O14931	intact:EBI-14061804|uniprotkb:Q7Z3M6|ensembl:ENSP00000341637|ensembl:ENSP00000434394	intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3	psi-mi:nr3l1_human(display_long)|uniprotkb:NCR3LG1(gene name)|psi-mi:NCR3LG1(display_short)|uniprotkb:B7 homolog 6(gene name synonym)|uniprotkb:B7H6(gene name synonym)	psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Li et al. (2011)	pubmed:21422170|imex:IM-25751	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14989399|wwpdb:3pv6|imex:IM-25751-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189368.1|ensembl:ENSG00000188211(gene)|ensembl:ENST00000338965(transcript)|ensembl:ENST00000530403(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR036946|rcsb pdb:3PV6|rcsb pdb:3PV7|rcsb pdb:4ZSO|rcsb pdb:6YJP|reactome:R-HSA-198933|dip:DIP-59940N	ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N	-	-	-	figure legend:Figure 1|comment:Alanine substitution of NKp30  Ile50 and Ser52 reduced binding 14-fold.  Replacement of NKp30 Ser52 by arginine,  reduced binding to B7-H6 by 150-fold.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.0x10^-6(molar)	2017/05/05	2017/05/25	rogid:zxyF+bJz/qWtsilosYWPqwnDUw89606	rogid:bS3R8rfddez5+tROQijf3FtslOU9606	rigid:RGs60g1CS7VjnF4PJeDm9zXbysI	false	sufficient binding region:25-262(IPR013783)|his tag:c-c	mutation decreasing interaction strength:50-50,52-52|mutation disrupting interaction strength:52-52|sufficient binding region:19-135(IPR013783)|mutation decreasing interaction strength:85-86	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)