#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P05532	uniprotkb:P26955	intact:EBI-8559255|uniprotkb:Q61417|uniprotkb:Q6QJB7|uniprotkb:Q8C8K9|intact:UNK-5369798|uniprotkb:Q61416|uniprotkb:Q61415|uniprotkb:Q6QJB8|uniprotkb:Q7TS86|uniprotkb:Q6LEE9|ensembl:ENSMUSP00000005815	intact:EBI-1810026|uniprotkb:Q3U7L5|ensembl:ENSMUSP00000094082|ensembl:ENSMUSP00000154836	psi-mi:kit_mouse(display_long)|uniprotkb:Proto-oncogene c-Kit(gene name synonym)|uniprotkb:Tyrosine-protein kinase Kit(gene name synonym)|uniprotkb:Kit(gene name)|psi-mi:Kit(display_short)|uniprotkb:Sl(gene name synonym)	psi-mi:il3rb_mouse(display_long)|uniprotkb:Csf2rb(gene name)|psi-mi:Csf2rb(display_short)|uniprotkb:Aic2b(gene name synonym)|uniprotkb:Csf2rb1(gene name synonym)|uniprotkb:Il3rb1(gene name synonym)|uniprotkb:GM-CSF/IL-3/IL-5 receptor common beta subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ye et al. (2011)	pubmed:21383156|doi:10.1073/pnas.1018002108|imex:IM-17536	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15914491|imex:IM-17536-1|dip:DIP-188856E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066922.2|refseq:NP_001116205.1|dip:DIP-59622N|go:"GO:1904251"(regulation of bile acid metabolic process)|go:"GO:1904343"(positive regulation of colon smooth muscle contraction)|go:"GO:1904349"(positive regulation of small intestine smooth muscle contraction)|go:"GO:1905065"(positive regulation of vascular associated smooth muscle cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027263|interpro:IPR036179|rcsb pdb:2O26|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-5673001|reactome:R-MMU-6811558|ensembl:ENSMUSG00000005672(gene)|ensembl:ENSMUST00000005815(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001650"(fibrillar center)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002020"(protease binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005020"(stem cell factor receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008542"(visual learning)|go:"GO:0008584"(male gonad development)|go:"GO:0009314"(response to radiation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0038093"(Fc receptor signaling pathway)|go:"GO:0038109"(Kit signaling pathway)|go:"GO:0038162"(erythropoietin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043235"(receptor complex)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043473"(pigmentation)|go:"GO:0043586"(tongue development)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048565"(digestive tract development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060374"(mast cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097324"(melanocyte migration)|go:"GO:0097326"(melanocyte adhesion)|go:"GO:0120072"(positive regulation of pyloric antrum smooth muscle contraction)	refseq:XP_006520450.1|refseq:NP_031806.3|dip:DIP-46527N|ensembl:ENSMUSG00000071713(gene)|ensembl:ENSMUST00000096355(transcript)|ensembl:ENSMUST00000230264(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011365(Cytokine IL-3/IL-5/GM-CSF receptor common beta chain)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116	psi-mi:"MI:0465"(dip)	comment:mint|function:"This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)"|function:"Defects in Kit are the cause of the white-spotting phenotype (W). White-spotting variants induces severe effects on pigmentation, gametogenesis and hematopoiesis. Mice homozygous for W42 die perinatally of macrocytic anemia"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:zyDKzVRXHq/sIEzdtIwQQJT4nmU10090	rogid:CE2TYcb44jcyGpv3t4MVpb3Oc9E10090	rigid:oyvvmL/yom8zDiPOCcYKE2Lh+Gg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05532	uniprotkb:P26955	intact:EBI-8559255|uniprotkb:Q61417|uniprotkb:Q6QJB7|uniprotkb:Q8C8K9|intact:UNK-5369798|uniprotkb:Q61416|uniprotkb:Q61415|uniprotkb:Q6QJB8|uniprotkb:Q7TS86|uniprotkb:Q6LEE9|ensembl:ENSMUSP00000005815	intact:EBI-1810026|uniprotkb:Q3U7L5|ensembl:ENSMUSP00000094082|ensembl:ENSMUSP00000154836	psi-mi:kit_mouse(display_long)|uniprotkb:Proto-oncogene c-Kit(gene name synonym)|uniprotkb:Tyrosine-protein kinase Kit(gene name synonym)|uniprotkb:Kit(gene name)|psi-mi:Kit(display_short)|uniprotkb:Sl(gene name synonym)	psi-mi:il3rb_mouse(display_long)|uniprotkb:Csf2rb(gene name)|psi-mi:Csf2rb(display_short)|uniprotkb:Aic2b(gene name synonym)|uniprotkb:Csf2rb1(gene name synonym)|uniprotkb:Il3rb1(gene name synonym)|uniprotkb:GM-CSF/IL-3/IL-5 receptor common beta subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ye et al. (2011)	pubmed:21383156|doi:10.1073/pnas.1018002108|imex:IM-17536	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15914525|imex:IM-17536-3|dip:DIP-188856E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066922.2|refseq:NP_001116205.1|dip:DIP-59622N|go:"GO:1904251"(regulation of bile acid metabolic process)|go:"GO:1904343"(positive regulation of colon smooth muscle contraction)|go:"GO:1904349"(positive regulation of small intestine smooth muscle contraction)|go:"GO:1905065"(positive regulation of vascular associated smooth muscle cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027263|interpro:IPR036179|rcsb pdb:2O26|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-5673001|reactome:R-MMU-6811558|ensembl:ENSMUSG00000005672(gene)|ensembl:ENSMUST00000005815(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001650"(fibrillar center)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002020"(protease binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005020"(stem cell factor receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008542"(visual learning)|go:"GO:0008584"(male gonad development)|go:"GO:0009314"(response to radiation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0038093"(Fc receptor signaling pathway)|go:"GO:0038109"(Kit signaling pathway)|go:"GO:0038162"(erythropoietin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043235"(receptor complex)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043473"(pigmentation)|go:"GO:0043586"(tongue development)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048565"(digestive tract development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060374"(mast cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097324"(melanocyte migration)|go:"GO:0097326"(melanocyte adhesion)|go:"GO:0120072"(positive regulation of pyloric antrum smooth muscle contraction)	refseq:XP_006520450.1|refseq:NP_031806.3|dip:DIP-46527N|ensembl:ENSMUSG00000071713(gene)|ensembl:ENSMUST00000096355(transcript)|ensembl:ENSMUST00000230264(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011365(Cytokine IL-3/IL-5/GM-CSF receptor common beta chain)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116	psi-mi:"MI:0465"(dip)	comment:mint|function:"This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)"|function:"Defects in Kit are the cause of the white-spotting phenotype (W). White-spotting variants induces severe effects on pigmentation, gametogenesis and hematopoiesis. Mice homozygous for W42 die perinatally of macrocytic anemia"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:zyDKzVRXHq/sIEzdtIwQQJT4nmU10090	rogid:CE2TYcb44jcyGpv3t4MVpb3Oc9E10090	rigid:oyvvmL/yom8zDiPOCcYKE2Lh+Gg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05532	uniprotkb:P26955	intact:EBI-8559255|uniprotkb:Q61417|uniprotkb:Q6QJB7|uniprotkb:Q8C8K9|intact:UNK-5369798|uniprotkb:Q61416|uniprotkb:Q61415|uniprotkb:Q6QJB8|uniprotkb:Q7TS86|uniprotkb:Q6LEE9|ensembl:ENSMUSP00000005815	intact:EBI-1810026|uniprotkb:Q3U7L5|ensembl:ENSMUSP00000094082|ensembl:ENSMUSP00000154836	psi-mi:kit_mouse(display_long)|uniprotkb:Proto-oncogene c-Kit(gene name synonym)|uniprotkb:Tyrosine-protein kinase Kit(gene name synonym)|uniprotkb:Kit(gene name)|psi-mi:Kit(display_short)|uniprotkb:Sl(gene name synonym)	psi-mi:il3rb_mouse(display_long)|uniprotkb:Csf2rb(gene name)|psi-mi:Csf2rb(display_short)|uniprotkb:Aic2b(gene name synonym)|uniprotkb:Csf2rb1(gene name synonym)|uniprotkb:Il3rb1(gene name synonym)|uniprotkb:GM-CSF/IL-3/IL-5 receptor common beta subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ye et al. (2011)	pubmed:21383156|doi:10.1073/pnas.1018002108|imex:IM-17536	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15914542|imex:IM-17536-4|dip:DIP-188856E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066922.2|refseq:NP_001116205.1|dip:DIP-59622N|go:"GO:1904251"(regulation of bile acid metabolic process)|go:"GO:1904343"(positive regulation of colon smooth muscle contraction)|go:"GO:1904349"(positive regulation of small intestine smooth muscle contraction)|go:"GO:1905065"(positive regulation of vascular associated smooth muscle cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027263|interpro:IPR036179|rcsb pdb:2O26|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-5673001|reactome:R-MMU-6811558|ensembl:ENSMUSG00000005672(gene)|ensembl:ENSMUST00000005815(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001650"(fibrillar center)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002020"(protease binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005020"(stem cell factor receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008542"(visual learning)|go:"GO:0008584"(male gonad development)|go:"GO:0009314"(response to radiation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0038093"(Fc receptor signaling pathway)|go:"GO:0038109"(Kit signaling pathway)|go:"GO:0038162"(erythropoietin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043235"(receptor complex)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043473"(pigmentation)|go:"GO:0043586"(tongue development)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048565"(digestive tract development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060374"(mast cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097324"(melanocyte migration)|go:"GO:0097326"(melanocyte adhesion)|go:"GO:0120072"(positive regulation of pyloric antrum smooth muscle contraction)	refseq:XP_006520450.1|refseq:NP_031806.3|dip:DIP-46527N|ensembl:ENSMUSG00000071713(gene)|ensembl:ENSMUST00000096355(transcript)|ensembl:ENSMUST00000230264(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011365(Cytokine IL-3/IL-5/GM-CSF receptor common beta chain)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116	psi-mi:"MI:0465"(dip)	comment:mint|function:"This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)"|function:"Defects in Kit are the cause of the white-spotting phenotype (W). White-spotting variants induces severe effects on pigmentation, gametogenesis and hematopoiesis. Mice homozygous for W42 die perinatally of macrocytic anemia"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:zyDKzVRXHq/sIEzdtIwQQJT4nmU10090	rogid:CE2TYcb44jcyGpv3t4MVpb3Oc9E10090	rigid:oyvvmL/yom8zDiPOCcYKE2Lh+Gg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05532	uniprotkb:P26955	intact:EBI-8559255|uniprotkb:Q61417|uniprotkb:Q6QJB7|uniprotkb:Q8C8K9|intact:UNK-5369798|uniprotkb:Q61416|uniprotkb:Q61415|uniprotkb:Q6QJB8|uniprotkb:Q7TS86|uniprotkb:Q6LEE9|ensembl:ENSMUSP00000005815	intact:EBI-1810026|uniprotkb:Q3U7L5|ensembl:ENSMUSP00000094082|ensembl:ENSMUSP00000154836	psi-mi:kit_mouse(display_long)|uniprotkb:Proto-oncogene c-Kit(gene name synonym)|uniprotkb:Tyrosine-protein kinase Kit(gene name synonym)|uniprotkb:Kit(gene name)|psi-mi:Kit(display_short)|uniprotkb:Sl(gene name synonym)	psi-mi:il3rb_mouse(display_long)|uniprotkb:Csf2rb(gene name)|psi-mi:Csf2rb(display_short)|uniprotkb:Aic2b(gene name synonym)|uniprotkb:Csf2rb1(gene name synonym)|uniprotkb:Il3rb1(gene name synonym)|uniprotkb:GM-CSF/IL-3/IL-5 receptor common beta subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ye et al. (2011)	pubmed:21383156|doi:10.1073/pnas.1018002108|imex:IM-17536	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15914508|imex:IM-17536-2|dip:DIP-188856E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066922.2|refseq:NP_001116205.1|dip:DIP-59622N|go:"GO:1904251"(regulation of bile acid metabolic process)|go:"GO:1904343"(positive regulation of colon smooth muscle contraction)|go:"GO:1904349"(positive regulation of small intestine smooth muscle contraction)|go:"GO:1905065"(positive regulation of vascular associated smooth muscle cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027263|interpro:IPR036179|rcsb pdb:2O26|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-5673001|reactome:R-MMU-6811558|ensembl:ENSMUSG00000005672(gene)|ensembl:ENSMUST00000005815(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001650"(fibrillar center)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002020"(protease binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005020"(stem cell factor receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008542"(visual learning)|go:"GO:0008584"(male gonad development)|go:"GO:0009314"(response to radiation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0038093"(Fc receptor signaling pathway)|go:"GO:0038109"(Kit signaling pathway)|go:"GO:0038162"(erythropoietin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043235"(receptor complex)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043473"(pigmentation)|go:"GO:0043586"(tongue development)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048565"(digestive tract development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060374"(mast cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097324"(melanocyte migration)|go:"GO:0097326"(melanocyte adhesion)|go:"GO:0120072"(positive regulation of pyloric antrum smooth muscle contraction)	refseq:XP_006520450.1|refseq:NP_031806.3|dip:DIP-46527N|ensembl:ENSMUSG00000071713(gene)|ensembl:ENSMUST00000096355(transcript)|ensembl:ENSMUST00000230264(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011365(Cytokine IL-3/IL-5/GM-CSF receptor common beta chain)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116	psi-mi:"MI:0465"(dip)	comment:mint|function:"This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)"|function:"Defects in Kit are the cause of the white-spotting phenotype (W). White-spotting variants induces severe effects on pigmentation, gametogenesis and hematopoiesis. Mice homozygous for W42 die perinatally of macrocytic anemia"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:zyDKzVRXHq/sIEzdtIwQQJT4nmU10090	rogid:CE2TYcb44jcyGpv3t4MVpb3Oc9E10090	rigid:oyvvmL/yom8zDiPOCcYKE2Lh+Gg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05532	uniprotkb:P26952	intact:EBI-8559255|uniprotkb:Q61417|uniprotkb:Q6QJB7|uniprotkb:Q8C8K9|intact:UNK-5369798|uniprotkb:Q61416|uniprotkb:Q61415|uniprotkb:Q6QJB8|uniprotkb:Q7TS86|uniprotkb:Q6LEE9|ensembl:ENSMUSP00000005815	intact:EBI-15914559|ensembl:ENSMUSP00000088079|ensembl:ENSMUSP00000153358|uniprotkb:B9VI80	psi-mi:kit_mouse(display_long)|uniprotkb:Proto-oncogene c-Kit(gene name synonym)|uniprotkb:Tyrosine-protein kinase Kit(gene name synonym)|uniprotkb:Kit(gene name)|psi-mi:Kit(display_short)|uniprotkb:Sl(gene name synonym)	psi-mi:il3ra_mouse(display_long)|uniprotkb:Il3ra(gene name)|psi-mi:Il3ra(display_short)|uniprotkb:Sut-1(gene name synonym)|uniprotkb:Interleukin-3 receptor class II alpha chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ye et al. (2011)	pubmed:21383156|doi:10.1073/pnas.1018002108|imex:IM-17536	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15914591|imex:IM-17536-5|dip:DIP-188857E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066922.2|refseq:NP_001116205.1|dip:DIP-59622N|go:"GO:1904251"(regulation of bile acid metabolic process)|go:"GO:1904343"(positive regulation of colon smooth muscle contraction)|go:"GO:1904349"(positive regulation of small intestine smooth muscle contraction)|go:"GO:1905065"(positive regulation of vascular associated smooth muscle cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027263|interpro:IPR036179|rcsb pdb:2O26|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-5673001|reactome:R-MMU-6811558|ensembl:ENSMUSG00000005672(gene)|ensembl:ENSMUST00000005815(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001650"(fibrillar center)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002020"(protease binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005020"(stem cell factor receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008542"(visual learning)|go:"GO:0008584"(male gonad development)|go:"GO:0009314"(response to radiation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0038093"(Fc receptor signaling pathway)|go:"GO:0038109"(Kit signaling pathway)|go:"GO:0038162"(erythropoietin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043235"(receptor complex)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043473"(pigmentation)|go:"GO:0043586"(tongue development)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048565"(digestive tract development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060374"(mast cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097324"(melanocyte migration)|go:"GO:0097326"(melanocyte adhesion)|go:"GO:0120072"(positive regulation of pyloric antrum smooth muscle contraction)	ensembl:ENSMUSG00000068758(gene)|ensembl:ENSMUST00000090591(transcript)|ensembl:ENSMUST00000224163(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|go:"GO:0043235"(receptor complex)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|refseq:NP_032395.1|dip:DIP-59621N	psi-mi:"MI:0465"(dip)	comment:mint|function:"This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)"|function:"Defects in Kit are the cause of the white-spotting phenotype (W). White-spotting variants induces severe effects on pigmentation, gametogenesis and hematopoiesis. Mice homozygous for W42 die perinatally of macrocytic anemia"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:zyDKzVRXHq/sIEzdtIwQQJT4nmU10090	rogid:X/mHDqLsQpuStraOp0WgCTufcyA10090	rigid:P7eeU0qKU5T4zeC/wNG9OCXqf4I	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)