#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P77239 uniprotkb:P38054 intact:EBI-1118842|ensemblbacteria:AAC73675|ensemblbacteria:BAA35208 intact:EBI-1126317|uniprotkb:P77767|ensemblbacteria:AAC73676|ensemblbacteria:BAA35215 psi-mi:cusb_ecoli(display_long)|uniprotkb:cusB(gene name)|psi-mi:cusB(display_short)|uniprotkb:b0574(locus name)|uniprotkb:JW0563(locus name)|uniprotkb:ylcD(gene name synonym) psi-mi:cusa_ecoli(display_long)|uniprotkb:cusA(gene name)|psi-mi:cusA(display_short)|uniprotkb:b0575(locus name)|uniprotkb:JW0564(locus name)|uniprotkb:ybdE(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Su et al. (2011) pubmed:21350490|doi:10.1038/nature09743|imex:IM-16231 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15913505|imex:IM-16231-1|dip:DIP-187281E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC73675(transcript)|ensemblbacteria:b0574(gene)|ensemblbacteria:BAA35208(gene)|ensemblbacteria:BAA35208(transcript)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0010272"(response to silver ion)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0015679"(plasma membrane copper ion transport)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0046688"(response to copper ion)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|interpro:IPR043602|rcsb pdb:3H94|rcsb pdb:3NE5|rcsb pdb:3OOC|rcsb pdb:3OPO|rcsb pdb:3OW7|rcsb pdb:3T51|rcsb pdb:3T53|rcsb pdb:3T56|rcsb pdb:4DNR|rcsb pdb:4DNT|rcsb pdb:4DOP|refseq:WP_000717157.1|refseq:NP_415106.1|dip:DIP-9346N refseq:WP_000573945.1|refseq:NP_415107.1|ensemblbacteria:AAC73676(transcript)|ensemblbacteria:b0575(gene)|ensemblbacteria:BAA35215(gene)|ensemblbacteria:BAA35215(transcript)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0010272"(response to silver ion)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0015080"(silver ion transmembrane transporter activity)|go:"GO:0015673"(silver ion transport)|go:"GO:0015679"(plasma membrane copper ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046688"(response to copper ion)|go:"GO:0060003"(copper ion export)|interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR004763(Heavy metal efflux pump CzcA)|interpro:IPR027463|rcsb pdb:3K07|rcsb pdb:3K0I|rcsb pdb:3KSO|rcsb pdb:3KSS|rcsb pdb:3NE5|rcsb pdb:3T51|rcsb pdb:3T53|rcsb pdb:3T56|rcsb pdb:4DNR|rcsb pdb:4DOP|rcsb pdb:7KF5|rcsb pdb:7KF6|rcsb pdb:7KF7|rcsb pdb:7KF8|rcsb pdb:4DNT|dip:DIP-9345N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:SK7ZwGaDq/1bNsGe5STc/cT6KKs83333 rogid:coMDgbW/gzb+pH6r7G4SG5A0/DU83333 rigid:8sQG22dZSlA5E+dRkGoxZKW2caw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P77239 uniprotkb:P38054 intact:EBI-1118842|ensemblbacteria:AAC73675|ensemblbacteria:BAA35208 intact:EBI-1126317|uniprotkb:P77767|ensemblbacteria:AAC73676|ensemblbacteria:BAA35215 psi-mi:cusb_ecoli(display_long)|uniprotkb:cusB(gene name)|psi-mi:cusB(display_short)|uniprotkb:b0574(locus name)|uniprotkb:JW0563(locus name)|uniprotkb:ylcD(gene name synonym) psi-mi:cusa_ecoli(display_long)|uniprotkb:cusA(gene name)|psi-mi:cusA(display_short)|uniprotkb:b0575(locus name)|uniprotkb:JW0564(locus name)|uniprotkb:ybdE(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Su et al. (2011) pubmed:21350490|doi:10.1038/nature09743|imex:IM-16231 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15913522|imex:IM-16231-2|dip:DIP-187281E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC73675(transcript)|ensemblbacteria:b0574(gene)|ensemblbacteria:BAA35208(gene)|ensemblbacteria:BAA35208(transcript)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0010272"(response to silver ion)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0015679"(plasma membrane copper ion transport)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0046688"(response to copper ion)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|interpro:IPR043602|rcsb pdb:3H94|rcsb pdb:3NE5|rcsb pdb:3OOC|rcsb pdb:3OPO|rcsb pdb:3OW7|rcsb pdb:3T51|rcsb pdb:3T53|rcsb pdb:3T56|rcsb pdb:4DNR|rcsb pdb:4DNT|rcsb pdb:4DOP|refseq:WP_000717157.1|refseq:NP_415106.1|dip:DIP-9346N refseq:WP_000573945.1|refseq:NP_415107.1|ensemblbacteria:AAC73676(transcript)|ensemblbacteria:b0575(gene)|ensemblbacteria:BAA35215(gene)|ensemblbacteria:BAA35215(transcript)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0010272"(response to silver ion)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0015080"(silver ion transmembrane transporter activity)|go:"GO:0015673"(silver ion transport)|go:"GO:0015679"(plasma membrane copper ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046688"(response to copper ion)|go:"GO:0060003"(copper ion export)|interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR004763(Heavy metal efflux pump CzcA)|interpro:IPR027463|rcsb pdb:3K07|rcsb pdb:3K0I|rcsb pdb:3KSO|rcsb pdb:3KSS|rcsb pdb:3NE5|rcsb pdb:3T51|rcsb pdb:3T53|rcsb pdb:3T56|rcsb pdb:4DNR|rcsb pdb:4DOP|rcsb pdb:7KF5|rcsb pdb:7KF6|rcsb pdb:7KF7|rcsb pdb:7KF8|rcsb pdb:4DNT|dip:DIP-9345N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:SK7ZwGaDq/1bNsGe5STc/cT6KKs83333 rogid:coMDgbW/gzb+pH6r7G4SG5A0/DU83333 rigid:8sQG22dZSlA5E+dRkGoxZKW2caw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)