#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P23921	uniprotkb:P23921	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913017|imex:IM-16086-1|dip:DIP-186976E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	rigid:noS7Fv+pxNwSB4X59F5/LRSUh2A	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21524	uniprotkb:P21524	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913033|imex:IM-16086-2|dip:DIP-17764E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	psi-mi:"MI:0465"(dip)	crc64:56BE1B077916E419	crc64:56BE1B077916E419	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rigid:ttZBX6bStUAFlhWtJ6zd4mQQ6/M	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21524	uniprotkb:P09938	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913049|imex:IM-16086-3|dip:DIP-81590E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938	psi-mi:"MI:0465"(dip)	crc64:56BE1B077916E419	crc64:DB98028408292042	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292	rigid:F39P36OhALSLdrLx+Y7B0cC6tx4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21524	uniprotkb:P49723	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913049|imex:IM-16086-3|dip:DIP-81590E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723	psi-mi:"MI:0465"(dip)	crc64:56BE1B077916E419	crc64:712853F2D87D3972	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292	rigid:F39P36OhALSLdrLx+Y7B0cC6tx4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21524	uniprotkb:P09938	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym)	psi-mi:"MI:0020"(transmission electron microscopy)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913067|imex:IM-16086-4|dip:DIP-81590E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938	psi-mi:"MI:0465"(dip)	crc64:56BE1B077916E419	crc64:DB98028408292042	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292	rigid:F39P36OhALSLdrLx+Y7B0cC6tx4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21524	uniprotkb:P49723	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym)	psi-mi:"MI:0020"(transmission electron microscopy)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913067|imex:IM-16086-4|dip:DIP-81590E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723	psi-mi:"MI:0465"(dip)	crc64:56BE1B077916E419	crc64:712853F2D87D3972	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292	rigid:F39P36OhALSLdrLx+Y7B0cC6tx4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P31350	uniprotkb:P23921	intact:EBI-2339245|uniprotkb:B2R9B5|uniprotkb:Q5WRU7|uniprotkb:J3KP43|intact:EBI-10973436|ensembl:ENSP00000302955|ensembl:ENSP00000493399	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	psi-mi:rir2_human(display_long)|uniprotkb:RRM2(gene name)|psi-mi:RRM2(display_short)|uniprotkb:RR2(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym)|uniprotkb:Ribonucleotide reductase small chain(gene name synonym)	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913085|imex:IM-16086-5|dip:DIP-40169E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001025.1|refseq:NP_001159403.1|dip:DIP-24232N|ensembl:ENSG00000171848(gene)|ensembl:ENST00000304567(transcript)|ensembl:ENST00000641198(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:2UW2|rcsb pdb:3OLJ|rcsb pdb:3VPM|rcsb pdb:3VPN|rcsb pdb:3VPO|reactome:R-HSA-499943|reactome:R-HSA-69205|reactome:R-HSA-8953750	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:vkkD9wGSPnsXX89dIQ53fhLD7uI9606	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	rigid:R5b3Xm9TFrnAkfyOxrhsg4D47rI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21524	uniprotkb:P21524	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913103|imex:IM-16086-6|dip:DIP-17764E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	psi-mi:"MI:0465"(dip)	crc64:56BE1B077916E419	crc64:56BE1B077916E419	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rigid:ttZBX6bStUAFlhWtJ6zd4mQQ6/M	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23921	uniprotkb:P23921	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913119|imex:IM-16086-7|dip:DIP-186976E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	rigid:noS7Fv+pxNwSB4X59F5/LRSUh2A	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21524	uniprotkb:P09938	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913154|imex:IM-16086-9|dip:DIP-81590E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938	psi-mi:"MI:0465"(dip)	crc64:56BE1B077916E419	crc64:DB98028408292042	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292	rigid:F39P36OhALSLdrLx+Y7B0cC6tx4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21524	uniprotkb:P49723	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913154|imex:IM-16086-9|dip:DIP-81590E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723	psi-mi:"MI:0465"(dip)	crc64:56BE1B077916E419	crc64:712853F2D87D3972	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292	rigid:F39P36OhALSLdrLx+Y7B0cC6tx4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49723	uniprotkb:P09938	intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C	intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W	psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym)	psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913135|imex:IM-16086-8|dip:DIP-10459E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723	refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938	psi-mi:"MI:0465"(dip)	crc64:712853F2D87D3972	crc64:DB98028408292042	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292	rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292	rigid:2MJOr+Yhrt/yzj5uIBakQZYZr5A	false	-	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23921	uniprotkb:P23921	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:"MI:0067"(light scattering)	Fairman et al. (2011)	pubmed:21336276|doi:10.1038/nsmb.2007|imex:IM-16086	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15913172|imex:IM-16086-10|dip:DIP-186976E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	rigid:noS7Fv+pxNwSB4X59F5/LRSUh2A	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)