#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q2VJ58 uniprotkb:Q5XE42 intact:EBI-15910909 intact:EBI-15910899|ensemblbacteria:AAT86321 psi-mi:q2vj58_strpy(display_long)|uniprotkb:E0F66_06230(orf name)|uniprotkb:ifs(gene name)|psi-mi:ifs(display_short)|uniprotkb:GTK54_00720(orf name)|uniprotkb:SPNIH34_01310(orf name) psi-mi:q5xe42_strp6(display_long)|uniprotkb:M6_Spy0186(locus name) psi-mi:"MI:0071"(molecular sieving) Smith et al. (2011) pubmed:21300288|doi:10.1016/j.str.2010.12.013|imex:IM-16140 taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes) taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15910919|imex:IM-16140-1|dip:DIP-187074E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032002|interpro:IPR038509|rcsb pdb:3PNT|rcsb pdb:3QB2|dip:DIP-59110N|refseq:WP_009880983.1 ensemblbacteria:AAT86321(transcript)|ensemblbacteria:M6_Spy0186(gene)|go:"GO:0008152"(metabolic process)|go:"GO:0061810"(NAD glycohydrolase activity)|interpro:IPR010900(Nicotine adenine dinucleotide glycohydrolase)|interpro:IPR041934|dip:DIP-59109N psi-mi:"MI:0465"(dip) crc64:BEB604A6FB730D7B crc64:D9FBF97B708F7828 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:UP/+NtgjsVKMc5bROEpqAaZd9BM1314 rogid:ZVGb8ln2zCQIKTjsbnzfuUsHDYg286636 rigid:Pm6vGvxYM/wn7yVUunBy0mUjY90 false - binding-associated region:194-454 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2VJ58 uniprotkb:Q5XE42 intact:EBI-15910909 intact:EBI-15910899|ensemblbacteria:AAT86321 psi-mi:q2vj58_strpy(display_long)|uniprotkb:E0F66_06230(orf name)|uniprotkb:ifs(gene name)|psi-mi:ifs(display_short)|uniprotkb:GTK54_00720(orf name)|uniprotkb:SPNIH34_01310(orf name) psi-mi:q5xe42_strp6(display_long)|uniprotkb:M6_Spy0186(locus name) psi-mi:"MI:0114"(x-ray crystallography) Smith et al. (2011) pubmed:21300288|doi:10.1016/j.str.2010.12.013|imex:IM-16140 taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes) taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15910960|imex:IM-16140-3|dip:DIP-187074E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032002|interpro:IPR038509|rcsb pdb:3PNT|rcsb pdb:3QB2|dip:DIP-59110N|refseq:WP_009880983.1 ensemblbacteria:AAT86321(transcript)|ensemblbacteria:M6_Spy0186(gene)|go:"GO:0008152"(metabolic process)|go:"GO:0061810"(NAD glycohydrolase activity)|interpro:IPR010900(Nicotine adenine dinucleotide glycohydrolase)|interpro:IPR041934|dip:DIP-59109N psi-mi:"MI:0465"(dip) crc64:BEB604A6FB730D7B crc64:D9FBF97B708F7828 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:UP/+NtgjsVKMc5bROEpqAaZd9BM1314 rogid:ZVGb8ln2zCQIKTjsbnzfuUsHDYg286636 rigid:Pm6vGvxYM/wn7yVUunBy0mUjY90 false - binding-associated region:194-454 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2VJ58 uniprotkb:Q5XE42 intact:EBI-15910909 intact:EBI-15910899|ensemblbacteria:AAT86321 psi-mi:q2vj58_strpy(display_long)|uniprotkb:E0F66_06230(orf name)|uniprotkb:ifs(gene name)|psi-mi:ifs(display_short)|uniprotkb:GTK54_00720(orf name)|uniprotkb:SPNIH34_01310(orf name) psi-mi:q5xe42_strp6(display_long)|uniprotkb:M6_Spy0186(locus name) psi-mi:"MI:0096"(pull down) Smith et al. (2011) pubmed:21300288|doi:10.1016/j.str.2010.12.013|imex:IM-16140 taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes) taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15910938|imex:IM-16140-2|dip:DIP-187074E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032002|interpro:IPR038509|rcsb pdb:3PNT|rcsb pdb:3QB2|dip:DIP-59110N|refseq:WP_009880983.1 ensemblbacteria:AAT86321(transcript)|ensemblbacteria:M6_Spy0186(gene)|go:"GO:0008152"(metabolic process)|go:"GO:0061810"(NAD glycohydrolase activity)|interpro:IPR010900(Nicotine adenine dinucleotide glycohydrolase)|interpro:IPR041934|dip:DIP-59109N psi-mi:"MI:0465"(dip) crc64:BEB604A6FB730D7B crc64:D9FBF97B708F7828 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:UP/+NtgjsVKMc5bROEpqAaZd9BM1314 rogid:ZVGb8ln2zCQIKTjsbnzfuUsHDYg286636 rigid:Pm6vGvxYM/wn7yVUunBy0mUjY90 false - binding-associated region:194-454|his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2VJ58 uniprotkb:Q5XE42 intact:EBI-15910909 intact:EBI-15910899|ensemblbacteria:AAT86321 psi-mi:q2vj58_strpy(display_long)|uniprotkb:E0F66_06230(orf name)|uniprotkb:ifs(gene name)|psi-mi:ifs(display_short)|uniprotkb:GTK54_00720(orf name)|uniprotkb:SPNIH34_01310(orf name) psi-mi:q5xe42_strp6(display_long)|uniprotkb:M6_Spy0186(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Smith et al. (2011) pubmed:21300288|doi:10.1016/j.str.2010.12.013|imex:IM-16140 taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes) taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15910979|imex:IM-16140-4|dip:DIP-187074E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032002|interpro:IPR038509|rcsb pdb:3PNT|rcsb pdb:3QB2|dip:DIP-59110N|refseq:WP_009880983.1 ensemblbacteria:AAT86321(transcript)|ensemblbacteria:M6_Spy0186(gene)|go:"GO:0008152"(metabolic process)|go:"GO:0061810"(NAD glycohydrolase activity)|interpro:IPR010900(Nicotine adenine dinucleotide glycohydrolase)|interpro:IPR041934|dip:DIP-59109N psi-mi:"MI:0465"(dip) crc64:BEB604A6FB730D7B crc64:D9FBF97B708F7828 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:UP/+NtgjsVKMc5bROEpqAaZd9BM1314 rogid:ZVGb8ln2zCQIKTjsbnzfuUsHDYg286636 rigid:Pm6vGvxYM/wn7yVUunBy0mUjY90 false - binding-associated region:194-454 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)