#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q50756	uniprotkb:Q50755	intact:EBI-15907507|ensemblbacteria:ADL59336|uniprotkb:D9PYN8|uniprotkb:Q50752	intact:EBI-15907525|ensemblbacteria:ADL58051|uniprotkb:D9PV04	psi-mi:hdra_mettm(display_long)|uniprotkb:CoB--CoM heterodisulfide reductase iron-sulfur subunit A(gene name synonym)|uniprotkb:MTBMA_c17680(locus name)|uniprotkb:hdrA(gene name)|psi-mi:hdrA(display_short)	psi-mi:hdrb_mettm(display_long)|uniprotkb:CoB--CoM heterodisulfide reductase subunit B(gene name synonym)|uniprotkb:MTBMA_c04500(locus name)|uniprotkb:hdrB(gene name)|psi-mi:hdrB(display_short)	psi-mi:"MI:0071"(molecular sieving)	Kaster et al. (2011)	pubmed:21262829|doi:10.1073/pnas.1016761108|imex:IM-17523	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15907559|imex:IM-17523-1|dip:DIP-188823E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ADL59336(transcript)|ensemblbacteria:MTBMA_c17680(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051912"(CoB--CoM heterodisulfide reductase activity)|interpro:IPR017896|interpro:IPR017900|interpro:IPR023753|interpro:IPR036188|interpro:IPR039650|refseq:WP_013296546.1|dip:DIP-59606N	ensemblbacteria:ADL58051(transcript)|ensemblbacteria:MTBMA_c04500(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0016020"(membrane)|go:"GO:0051912"(CoB--CoM heterodisulfide reductase activity)|interpro:IPR004017(Cysteine-rich region, CCG)|interpro:IPR017678(CoB/CoM heterodisulphide reductase, subunit B)|refseq:WP_013295277.1|dip:DIP-59607N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	-	2017/08/07	2017/08/10	rogid:ioG1DuK1Y8FeYWyoMv2k8zJxhEg79929	rogid:YdoE+AJTwvfcJtDqm04PD8Ajslk79929	rigid:Yvb5wSIopZZvvoj7MfQ1QGW8f9A	false	-	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q50756	uniprotkb:Q50754	intact:EBI-15907507|ensemblbacteria:ADL59336|uniprotkb:D9PYN8|uniprotkb:Q50752	intact:EBI-15907540|ensemblbacteria:ADL58050|uniprotkb:D9PV03	psi-mi:hdra_mettm(display_long)|uniprotkb:CoB--CoM heterodisulfide reductase iron-sulfur subunit A(gene name synonym)|uniprotkb:MTBMA_c17680(locus name)|uniprotkb:hdrA(gene name)|psi-mi:hdrA(display_short)	psi-mi:hdrc_mettm(display_long)|uniprotkb:CoB--CoM heterodisulfide reductase iron-sulfur subunit C(gene name synonym)|uniprotkb:MTBMA_c04490(locus name)|uniprotkb:hdrC(gene name)|psi-mi:hdrC(display_short)	psi-mi:"MI:0071"(molecular sieving)	Kaster et al. (2011)	pubmed:21262829|doi:10.1073/pnas.1016761108|imex:IM-17523	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15907559|imex:IM-17523-1|dip:DIP-188823E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ADL59336(transcript)|ensemblbacteria:MTBMA_c17680(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051912"(CoB--CoM heterodisulfide reductase activity)|interpro:IPR017896|interpro:IPR017900|interpro:IPR023753|interpro:IPR036188|interpro:IPR039650|refseq:WP_013296546.1|dip:DIP-59606N	ensemblbacteria:ADL58050(transcript)|ensemblbacteria:MTBMA_c04490(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0051912"(CoB--CoM heterodisulfide reductase activity)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR017680(CoB--CoM heterodisulphide reductase, subunit C)|interpro:IPR017896|interpro:IPR017900|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|refseq:WP_013295276.1|dip:DIP-59608N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	-	2017/08/07	2017/08/10	rogid:ioG1DuK1Y8FeYWyoMv2k8zJxhEg79929	rogid:uf04xcbvi54vNcwnzrL3LXd36TY79929	rigid:Yvb5wSIopZZvvoj7MfQ1QGW8f9A	false	-	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q50756	uniprotkb:P60227	intact:EBI-15907507|ensemblbacteria:ADL59336|uniprotkb:D9PYN8|uniprotkb:Q50752	intact:EBI-15907463|ensemblbacteria:ADL59096|uniprotkb:D9PXZ8	psi-mi:hdra_mettm(display_long)|uniprotkb:CoB--CoM heterodisulfide reductase iron-sulfur subunit A(gene name synonym)|uniprotkb:MTBMA_c17680(locus name)|uniprotkb:hdrA(gene name)|psi-mi:hdrA(display_short)	psi-mi:mvha_mettm(display_long)|uniprotkb:mvhA(gene name)|psi-mi:mvhA(display_short)|uniprotkb:Methyl viologen-reducing hydrogenase subunit alpha(gene name synonym)|uniprotkb:MTBMA_c15170(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kaster et al. (2011)	pubmed:21262829|doi:10.1073/pnas.1016761108|imex:IM-17523	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15907559|imex:IM-17523-1|dip:DIP-188823E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ADL59336(transcript)|ensemblbacteria:MTBMA_c17680(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051912"(CoB--CoM heterodisulfide reductase activity)|interpro:IPR017896|interpro:IPR017900|interpro:IPR023753|interpro:IPR036188|interpro:IPR039650|refseq:WP_013296546.1|dip:DIP-59606N	ensemblbacteria:ADL59096(transcript)|ensemblbacteria:MTBMA_c15170(gene)|go:"GO:0008901"(ferredoxin hydrogenase activity)|go:"GO:0016151"(nickel cation binding)|interpro:IPR001501(Nickel-dependent hydrogenase, large subunit)|interpro:IPR018194|interpro:IPR029014|refseq:WP_013296307.1|dip:DIP-59603N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	-	2017/08/07	2017/08/10	rogid:ioG1DuK1Y8FeYWyoMv2k8zJxhEg79929	rogid:4UEbxHvfJASukbxRpLhzXFwFU1I79929	rigid:Yvb5wSIopZZvvoj7MfQ1QGW8f9A	false	-	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q50756	uniprotkb:P60238	intact:EBI-15907507|ensemblbacteria:ADL59336|uniprotkb:D9PYN8|uniprotkb:Q50752	intact:EBI-15907478|ensemblbacteria:ADL59098|uniprotkb:D9PY00	psi-mi:hdra_mettm(display_long)|uniprotkb:CoB--CoM heterodisulfide reductase iron-sulfur subunit A(gene name synonym)|uniprotkb:MTBMA_c17680(locus name)|uniprotkb:hdrA(gene name)|psi-mi:hdrA(display_short)	psi-mi:mvhd_mettm(display_long)|uniprotkb:mvhD(gene name)|psi-mi:mvhD(display_short)|uniprotkb:Methyl viologen-reducing hydrogenase subunit delta(gene name synonym)|uniprotkb:MTBMA_c15190(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kaster et al. (2011)	pubmed:21262829|doi:10.1073/pnas.1016761108|imex:IM-17523	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15907559|imex:IM-17523-1|dip:DIP-188823E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ADL59336(transcript)|ensemblbacteria:MTBMA_c17680(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051912"(CoB--CoM heterodisulfide reductase activity)|interpro:IPR017896|interpro:IPR017900|interpro:IPR023753|interpro:IPR036188|interpro:IPR039650|refseq:WP_013296546.1|dip:DIP-59606N	ensemblbacteria:ADL59098(transcript)|ensemblbacteria:MTBMA_c15190(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR003813(Methyl-viologen-reducing hydrogenase, delta subunit)|refseq:WP_013296309.1|dip:DIP-59604N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	-	2017/08/07	2017/08/10	rogid:ioG1DuK1Y8FeYWyoMv2k8zJxhEg79929	rogid:G16LtTigF7CwwNgVUH/nu2T/wlw79929	rigid:Yvb5wSIopZZvvoj7MfQ1QGW8f9A	false	-	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q50756	uniprotkb:P60239	intact:EBI-15907507|ensemblbacteria:ADL59336|uniprotkb:D9PYN8|uniprotkb:Q50752	intact:EBI-15907494|ensemblbacteria:ADL59097|uniprotkb:D9PXZ9	psi-mi:hdra_mettm(display_long)|uniprotkb:CoB--CoM heterodisulfide reductase iron-sulfur subunit A(gene name synonym)|uniprotkb:MTBMA_c17680(locus name)|uniprotkb:hdrA(gene name)|psi-mi:hdrA(display_short)	psi-mi:mvhg_mettm(display_long)|uniprotkb:mvhG(gene name)|psi-mi:mvhG(display_short)|uniprotkb:Methyl viologen-reducing hydrogenase subunit gamma(gene name synonym)|uniprotkb:MTBMA_c15180(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kaster et al. (2011)	pubmed:21262829|doi:10.1073/pnas.1016761108|imex:IM-17523	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15907559|imex:IM-17523-1|dip:DIP-188823E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ADL59336(transcript)|ensemblbacteria:MTBMA_c17680(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051912"(CoB--CoM heterodisulfide reductase activity)|interpro:IPR017896|interpro:IPR017900|interpro:IPR023753|interpro:IPR036188|interpro:IPR039650|refseq:WP_013296546.1|dip:DIP-59606N	ensemblbacteria:ADL59097(transcript)|ensemblbacteria:MTBMA_c15180(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0051536"(iron-sulfur cluster binding)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR037024|refseq:WP_013296308.1|dip:DIP-59605N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:79929(mettm)|taxid:79929("Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)")	-	2017/08/07	2017/08/10	rogid:ioG1DuK1Y8FeYWyoMv2k8zJxhEg79929	rogid:3tWqJcy0Dw2uYxjes5iz/luod4Q79929	rigid:Yvb5wSIopZZvvoj7MfQ1QGW8f9A	false	-	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)