#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P9WLZ7 uniprotkb:P9WLZ7 intact:EBI-2602906|uniprotkb:L0T6M8|uniprotkb:Q11034 intact:EBI-2602906|uniprotkb:L0T6M8|uniprotkb:Q11034 psi-mi:mtdrp_myctu(display_long)|uniprotkb:Anti-sigma-F factor Rv1364c(gene name synonym)|uniprotkb:Protein-serine/threonine phosphatase(gene name synonym)|uniprotkb:Putative multidomain regulator of SigF(gene name synonym)|uniprotkb:Serine/threonine-protein kinase(gene name synonym)|uniprotkb:MTCY02B10.28c(orf name)|uniprotkb:Rv1364c(locus name) psi-mi:mtdrp_myctu(display_long)|uniprotkb:Anti-sigma-F factor Rv1364c(gene name synonym)|uniprotkb:Protein-serine/threonine phosphatase(gene name synonym)|uniprotkb:Putative multidomain regulator of SigF(gene name synonym)|uniprotkb:Serine/threonine-protein kinase(gene name synonym)|uniprotkb:MTCY02B10.28c(orf name)|uniprotkb:Rv1364c(locus name) psi-mi:"MI:0114"(x-ray crystallography) King-Scott et al. (2011) pubmed:21220116|doi:10.1016/j.str.2010.11.010|imex:IM-16134 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15903975|imex:IM-16134-1|dip:DIP-140767E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|rcsb pdb:3K3C|rcsb pdb:3K3D|rcsb pdb:3KE6|rcsb pdb:3KX0|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_177802.1|refseq:WP_003916806.1|interpro:IPR035965|interpro:IPR036457|interpro:IPR036513|interpro:IPR036890 interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|rcsb pdb:3K3C|rcsb pdb:3K3D|rcsb pdb:3KE6|rcsb pdb:3KX0|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_177802.1|refseq:WP_003916806.1|interpro:IPR035965|interpro:IPR036457|interpro:IPR036513|interpro:IPR036890 psi-mi:"MI:0465"(dip) crc64:51F29AA39D9C8B9F crc64:51F29AA39D9C8B9F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:zdvuR4fkUtHWJsqP4hdB7mjIktw83332 rogid:zdvuR4fkUtHWJsqP4hdB7mjIktw83332 rigid:xnUqZC8UWRGe1S23w5zW5JejYQ8 false binding-associated region:169-539 binding-associated region:169-539 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WLZ7 uniprotkb:P9WLZ7 intact:EBI-2602906|uniprotkb:L0T6M8|uniprotkb:Q11034 intact:EBI-2602906|uniprotkb:L0T6M8|uniprotkb:Q11034 psi-mi:mtdrp_myctu(display_long)|uniprotkb:Anti-sigma-F factor Rv1364c(gene name synonym)|uniprotkb:Protein-serine/threonine phosphatase(gene name synonym)|uniprotkb:Putative multidomain regulator of SigF(gene name synonym)|uniprotkb:Serine/threonine-protein kinase(gene name synonym)|uniprotkb:MTCY02B10.28c(orf name)|uniprotkb:Rv1364c(locus name) psi-mi:mtdrp_myctu(display_long)|uniprotkb:Anti-sigma-F factor Rv1364c(gene name synonym)|uniprotkb:Protein-serine/threonine phosphatase(gene name synonym)|uniprotkb:Putative multidomain regulator of SigF(gene name synonym)|uniprotkb:Serine/threonine-protein kinase(gene name synonym)|uniprotkb:MTCY02B10.28c(orf name)|uniprotkb:Rv1364c(locus name) psi-mi:"MI:0071"(molecular sieving) King-Scott et al. (2011) pubmed:21220116|doi:10.1016/j.str.2010.11.010|imex:IM-16134 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15903993|imex:IM-16134-2|dip:DIP-140767E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|rcsb pdb:3K3C|rcsb pdb:3K3D|rcsb pdb:3KE6|rcsb pdb:3KX0|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_177802.1|refseq:WP_003916806.1|interpro:IPR035965|interpro:IPR036457|interpro:IPR036513|interpro:IPR036890 interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|rcsb pdb:3K3C|rcsb pdb:3K3D|rcsb pdb:3KE6|rcsb pdb:3KX0|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_177802.1|refseq:WP_003916806.1|interpro:IPR035965|interpro:IPR036457|interpro:IPR036513|interpro:IPR036890 psi-mi:"MI:0465"(dip) crc64:51F29AA39D9C8B9F crc64:51F29AA39D9C8B9F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:zdvuR4fkUtHWJsqP4hdB7mjIktw83332 rogid:zdvuR4fkUtHWJsqP4hdB7mjIktw83332 rigid:xnUqZC8UWRGe1S23w5zW5JejYQ8 false sufficient binding region:1-147|sufficient binding region:169-539 sufficient binding region:1-147|sufficient binding region:169-539 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WLZ7 uniprotkb:P9WLZ7 intact:EBI-2602906|uniprotkb:L0T6M8|uniprotkb:Q11034 intact:EBI-2602906|uniprotkb:L0T6M8|uniprotkb:Q11034 psi-mi:mtdrp_myctu(display_long)|uniprotkb:Anti-sigma-F factor Rv1364c(gene name synonym)|uniprotkb:Protein-serine/threonine phosphatase(gene name synonym)|uniprotkb:Putative multidomain regulator of SigF(gene name synonym)|uniprotkb:Serine/threonine-protein kinase(gene name synonym)|uniprotkb:MTCY02B10.28c(orf name)|uniprotkb:Rv1364c(locus name) psi-mi:mtdrp_myctu(display_long)|uniprotkb:Anti-sigma-F factor Rv1364c(gene name synonym)|uniprotkb:Protein-serine/threonine phosphatase(gene name synonym)|uniprotkb:Putative multidomain regulator of SigF(gene name synonym)|uniprotkb:Serine/threonine-protein kinase(gene name synonym)|uniprotkb:MTCY02B10.28c(orf name)|uniprotkb:Rv1364c(locus name) psi-mi:"MI:0826"(x ray scattering) King-Scott et al. (2011) pubmed:21220116|doi:10.1016/j.str.2010.11.010|imex:IM-16134 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15904013|imex:IM-16134-3|dip:DIP-140767E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|rcsb pdb:3K3C|rcsb pdb:3K3D|rcsb pdb:3KE6|rcsb pdb:3KX0|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_177802.1|refseq:WP_003916806.1|interpro:IPR035965|interpro:IPR036457|interpro:IPR036513|interpro:IPR036890 interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|rcsb pdb:3K3C|rcsb pdb:3K3D|rcsb pdb:3KE6|rcsb pdb:3KX0|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_177802.1|refseq:WP_003916806.1|interpro:IPR035965|interpro:IPR036457|interpro:IPR036513|interpro:IPR036890 psi-mi:"MI:0465"(dip) crc64:51F29AA39D9C8B9F crc64:51F29AA39D9C8B9F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:zdvuR4fkUtHWJsqP4hdB7mjIktw83332 rogid:zdvuR4fkUtHWJsqP4hdB7mjIktw83332 rigid:xnUqZC8UWRGe1S23w5zW5JejYQ8 false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WLZ7 uniprotkb:P9WLZ7 intact:EBI-2602906|uniprotkb:L0T6M8|uniprotkb:Q11034 intact:EBI-2602906|uniprotkb:L0T6M8|uniprotkb:Q11034 psi-mi:mtdrp_myctu(display_long)|uniprotkb:Anti-sigma-F factor Rv1364c(gene name synonym)|uniprotkb:Protein-serine/threonine phosphatase(gene name synonym)|uniprotkb:Putative multidomain regulator of SigF(gene name synonym)|uniprotkb:Serine/threonine-protein kinase(gene name synonym)|uniprotkb:MTCY02B10.28c(orf name)|uniprotkb:Rv1364c(locus name) psi-mi:mtdrp_myctu(display_long)|uniprotkb:Anti-sigma-F factor Rv1364c(gene name synonym)|uniprotkb:Protein-serine/threonine phosphatase(gene name synonym)|uniprotkb:Putative multidomain regulator of SigF(gene name synonym)|uniprotkb:Serine/threonine-protein kinase(gene name synonym)|uniprotkb:MTCY02B10.28c(orf name)|uniprotkb:Rv1364c(locus name) psi-mi:"MI:0114"(x-ray crystallography) King-Scott et al. (2011) pubmed:21220116|doi:10.1016/j.str.2010.11.010|imex:IM-16134 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15904031|imex:IM-16134-4|dip:DIP-140767E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|rcsb pdb:3K3C|rcsb pdb:3K3D|rcsb pdb:3KE6|rcsb pdb:3KX0|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_177802.1|refseq:WP_003916806.1|interpro:IPR035965|interpro:IPR036457|interpro:IPR036513|interpro:IPR036890 interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|rcsb pdb:3K3C|rcsb pdb:3K3D|rcsb pdb:3KE6|rcsb pdb:3KX0|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_177802.1|refseq:WP_003916806.1|interpro:IPR035965|interpro:IPR036457|interpro:IPR036513|interpro:IPR036890 psi-mi:"MI:0465"(dip) crc64:51F29AA39D9C8B9F crc64:51F29AA39D9C8B9F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:zdvuR4fkUtHWJsqP4hdB7mjIktw83332 rogid:zdvuR4fkUtHWJsqP4hdB7mjIktw83332 rigid:xnUqZC8UWRGe1S23w5zW5JejYQ8 false binding-associated region:1-147 binding-associated region:1-147 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)