#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BTM9 uniprotkb:Q6P2Q9 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-538479|uniprotkb:O14547|uniprotkb:O75965|ensembl:ENSP00000304350|ensembl:ENSP00000460348|ensembl:ENSP00000479194|ensembl:ENSP00000488611 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:prp8_human(display_long)|uniprotkb:Splicing factor Prp8(gene name synonym)|uniprotkb:PRP8 homolog(gene name synonym)|uniprotkb:220 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:p220(gene name synonym)|uniprotkb:PRPC8(gene name synonym)|uniprotkb:PRPF8(gene name)|psi-mi:PRPF8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902685|imex:IM-21221-2|dip:DIP-191135E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_006436.3|ensembl:ENSG00000174231(gene)|ensembl:ENSG00000274442(gene)|ensembl:ENST00000304992(transcript)|ensembl:ENST00000572621(transcript)|ensembl:ENST00000614672(transcript)|ensembl:ENST00000634039(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|mint:Q6P2Q9|rcsb pdb:3E9L|rcsb pdb:3ENB|rcsb pdb:3JCR|rcsb pdb:3LRU|rcsb pdb:4JK7|rcsb pdb:4JK8|rcsb pdb:4JK9|rcsb pdb:4JKA|rcsb pdb:4JKB|rcsb pdb:4JKC|rcsb pdb:4JKD|rcsb pdb:4JKE|rcsb pdb:4JKF|rcsb pdb:4JKG|rcsb pdb:4JKH|rcsb pdb:4KIT|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5XJC|dip:DIP-29614N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:I0ot8b3pvieXRI66omFm145sGVA9606 rigid:aoXSiy7mySK3+iDW2+B6YzkznMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:P80188 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-11911016|uniprotkb:A6NII8|uniprotkb:B4DWV4|uniprotkb:B7ZAA2|uniprotkb:P30150|uniprotkb:Q5SYV9|uniprotkb:Q5SYW0|uniprotkb:Q6FGL5|uniprotkb:Q92683|ensembl:ENSP00000277480|ensembl:ENSP00000362108 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:ngal_human(display_long)|uniprotkb:Siderocalin(gene name synonym)|uniprotkb:LCN2(gene name)|psi-mi:LCN2(display_short)|uniprotkb:25 kDa alpha-2-microglobulin-related subunit of MMP-9(gene name synonym)|uniprotkb:HNL(gene name synonym)|uniprotkb:Lipocalin-2(gene name synonym)|uniprotkb:NGAL(gene name synonym)|uniprotkb:Oncogene 24p3(gene name synonym)|uniprotkb:p25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902685|imex:IM-21221-2|dip:DIP-191135E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_005555.2|dip:DIP-29952N|ensembl:ENSG00000148346(gene)|ensembl:ENST00000277480(transcript)|ensembl:ENST00000373017(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0009635"(response to herbicide)|go:"GO:0009637"(response to blue light)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015891"(siderophore transport)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036094"(small molecule binding)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0042493"|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0097577"(sequestering of iron ion)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903981"(enterobactin binding)|go:"GO:1904440"(positive regulation of iron ion import across plasma membrane)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002345(Lipocalin)|interpro:IPR003087(Neutrophil gelatinase-associated lipocalin)|interpro:IPR012674(Calycin)|interpro:IPR022272|mint:P80188|rcsb pdb:1DFV|rcsb pdb:1L6M|rcsb pdb:1NGL|rcsb pdb:1QQS|rcsb pdb:1X71|rcsb pdb:1X89|rcsb pdb:1X8U|rcsb pdb:3BY0|rcsb pdb:3CBC|rcsb pdb:3CMP|rcsb pdb:3DSZ|rcsb pdb:3DTQ|rcsb pdb:3FW4|rcsb pdb:3FW5|rcsb pdb:3HWD|rcsb pdb:3HWE|rcsb pdb:3HWF|rcsb pdb:3HWG|rcsb pdb:3I0A|rcsb pdb:3K3L|rcsb pdb:3PEC|rcsb pdb:3PED|rcsb pdb:3T1D|rcsb pdb:3TF6|rcsb pdb:3TZS|rcsb pdb:3U0D|rcsb pdb:4GH7|rcsb pdb:4IAW|rcsb pdb:4IAX|rcsb pdb:4K19|rcsb pdb:4MVI|rcsb pdb:4MVK|rcsb pdb:4MVL|rcsb pdb:4QAE|rcsb pdb:4ZFX|rcsb pdb:4ZHC|rcsb pdb:4ZHD|rcsb pdb:4ZHF|rcsb pdb:4ZHG|rcsb pdb:4ZHH|rcsb pdb:5JR8|rcsb pdb:5KHP|go:"GO:1905956"(positive regulation of endothelial tube morphogenesis)|rcsb pdb:5KIC|rcsb pdb:5KID|rcsb pdb:5MHH|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:5NKN|rcsb pdb:6GQZ|rcsb pdb:6GR0|rcsb pdb:6QMU|rcsb pdb:6S8V|rcsb pdb:6SUA|rcsb pdb:6Z2C|rcsb pdb:6Z6Z|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-917937|rcsb pdb:6O5D psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:m5Q9A8rMP15tT8/Sdt2q/a3Xsr89606 rigid:aoXSiy7mySK3+iDW2+B6YzkznMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:P02787 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-714319|uniprotkb:O43890|uniprotkb:Q9NQB8|uniprotkb:Q9UHV0|uniprotkb:Q1HBA5|ensembl:ENSP00000385834 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:trfe_human(display_long)|uniprotkb:Siderophilin(gene name synonym)|uniprotkb:Beta-1 metal-binding globulin(gene name synonym)|uniprotkb:TF(gene name)|psi-mi:TF(display_short)|uniprotkb:PRO1400(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902685|imex:IM-21221-2|dip:DIP-191135E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_001054.1|rcsb pdb:1JQF|rcsb pdb:1N7W|rcsb pdb:1N7X|rcsb pdb:1N84|rcsb pdb:1OQG|rcsb pdb:1OQH|rcsb pdb:1RYO|rcsb pdb:1SUV|rcsb pdb:2HAU|rcsb pdb:2HAV|rcsb pdb:2O7U|rcsb pdb:2O84|rcsb pdb:3FGS|rcsb pdb:3QYT|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:1FQF|rcsb pdb:3S9N|rcsb pdb:3SKP|rcsb pdb:3V83|rcsb pdb:3V89|rcsb pdb:3V8X|rcsb pdb:4H0W|rcsb pdb:4X1B|rcsb pdb:4X1D|rcsb pdb:5DYH|rcsb pdb:5H52|rcsb pdb:5WTD|rcsb pdb:5X5P|rcsb pdb:5Y6K|rcsb pdb:6CTC|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:3VE1|rcsb pdb:6JAS|rcsb pdb:6SOY|rcsb pdb:6SOZ|rcsb pdb:6UJ6|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8957275|reactome:R-HSA-917937|reactome:R-HSA-917977|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045178"(basal part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0072562"(blood microparticle)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030685|mint:P02787|rcsb pdb:1A8E|go:"GO:0034774"(secretory granule lumen)|rcsb pdb:1A8F|rcsb pdb:1B3E|rcsb pdb:1BP5|rcsb pdb:1BTJ|rcsb pdb:1D3K|rcsb pdb:1D4N|rcsb pdb:1DTG|rcsb pdb:1FQE|ensembl:ENSG00000091513(gene)|ensembl:ENST00000402696(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031982"(vesicle)|go:"GO:0034756"(regulation of iron ion transport)|refseq:XP_016862578.1|refseq:XP_016862579.1|dip:DIP-2738N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:CN9nME9TVV6/FGrhH6XHtJF9/HI9606 rigid:aoXSiy7mySK3+iDW2+B6YzkznMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:O15294 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902685|imex:IM-21221-2|dip:DIP-191135E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rigid:aoXSiy7mySK3+iDW2+B6YzkznMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:P02790 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-1223791|uniprotkb:B2R957|ensembl:ENSP00000265983 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:hemo_human(display_long)|uniprotkb:HPX(gene name)|psi-mi:HPX(display_short)|uniprotkb:Beta-1B-glycoprotein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902685|imex:IM-21221-2|dip:DIP-191135E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_000604.1|dip:DIP-38339N|ensembl:ENSG00000110169(gene)|ensembl:ENST00000265983(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0042168"(heme metabolic process)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0046872"(metal ion binding)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0072562"(blood microparticle)|interpro:IPR000585(Hemopexin)|interpro:IPR016358(Hemopexin, chordata)|interpro:IPR018486|interpro:IPR018487|interpro:IPR036375|mint:P02790|reactome:R-HSA-2168880 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:ee7ibGnypa0mhzKxQrBukKnrt+Y9606 rigid:aoXSiy7mySK3+iDW2+B6YzkznMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q92900 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902685|imex:IM-21221-2|dip:DIP-191135E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rigid:aoXSiy7mySK3+iDW2+B6YzkznMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q15717 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902685|imex:IM-21221-2|dip:DIP-191135E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606 rigid:aoXSiy7mySK3+iDW2+B6YzkznMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q08J23 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-1642839|intact:EBI-2839052|uniprotkb:A8K529|uniprotkb:B3KP09|uniprotkb:G3V1R4|uniprotkb:Q9BVN4|uniprotkb:Q9H858|uniprotkb:Q9NXD9|uniprotkb:B2RNR4|intact:EBI-2556652|uniprotkb:B4DQW2|ensembl:ENSP00000264670 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:nsun2_human(display_long)|uniprotkb:NSUN2(gene name)|psi-mi:NSUN2(display_short)|uniprotkb:SAKI(gene name synonym)|uniprotkb:TRM4(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 2(gene name synonym)|uniprotkb:tRNA methyltransferase 4 homolog(gene name synonym)|uniprotkb:Substrate of AIM1/Aurora kinase B(gene name synonym)|uniprotkb:Myc-induced SUN domain-containing protein(gene name synonym)|uniprotkb:"mRNA cytosine C(5)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA cytosine C(5)-methyltransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902685|imex:IM-21221-2|dip:DIP-191135E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_001180384.1|refseq:NP_060225.4|dip:DIP-52456N|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006400"(tRNA modification)|go:"GO:0007286"(spermatid development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016428"("tRNA (cytosine-5-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0033313"(meiotic cell cycle checkpoint signaling)|go:"GO:0033391"(chromatoid body)|go:"GO:0036416"(tRNA stabilization)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051301"(cell division)|go:"GO:0062152"("mRNA (cytidine-5-)-methyltransferase activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR023270|interpro:IPR029063|mint:Q08J23|reactome:R-HSA-6782315|ensembl:ENSG00000037474(gene)|ensembl:ENST00000264670(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001510"(RNA methylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:k3hK/9cjuy5c4PyDGgCt0LsVtdo9606 rigid:aoXSiy7mySK3+iDW2+B6YzkznMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q96K76 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-2514143|ensembl:ENSP00000382382|uniprotkb:Q86Y73|uniprotkb:Q9NWN1|uniprotkb:Q9BWI0|uniprotkb:Q8TEP6|uniprotkb:Q658U0|intact:EBI-11020736|uniprotkb:B3KXF5|uniprotkb:E9PM46 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:ubp47_human(display_long)|uniprotkb:USP47(gene name)|psi-mi:USP47(display_short)|uniprotkb:Ubiquitin-specific-processing protease 47(gene name synonym)|uniprotkb:Deubiquitinating enzyme 47(gene name synonym)|uniprotkb:Ubiquitin thioesterase 47(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902685|imex:IM-21221-2|dip:DIP-191135E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_001269588.1|ensembl:ENSG00000170242(gene)|ensembl:ENST00000399455(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR029071|interpro:IPR038765|mint:Q96K76|reactome:R-HSA-5689880|refseq:NP_001317137.1|refseq:NP_060414.3|dip:DIP-53629N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:XPhYwHpj4bDPhA/uMESoVswI6Jo9606 rigid:aoXSiy7mySK3+iDW2+B6YzkznMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:O95396 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-373206|ensembl:ENSP00000244051 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:mocs3_human(display_long)|uniprotkb:MOCS3(gene name)|psi-mi:MOCS3(display_short)|uniprotkb:Molybdopterin synthase sulfurylase(gene name synonym)|uniprotkb:UBA4(gene name synonym)|uniprotkb:Molybdenum cofactor synthesis protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902685|imex:IM-21221-2|dip:DIP-191135E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_055299.1|ensembl:ENSG00000124217(gene)|ensembl:ENST00000244051(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0042292"(URM1 activating enzyme activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0061604"(molybdopterin-synthase sulfurtransferase activity)|go:"GO:0061605"(molybdopterin-synthase adenylyltransferase activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR001763(Rhodanese-like)|interpro:IPR028885|interpro:IPR035985|interpro:IPR036873|rcsb pdb:3I2V|reactome:R-HSA-947581|dip:DIP-31168N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:yIgGuZAL6kHczqsQriXyJBa3fGQ9606 rigid:aoXSiy7mySK3+iDW2+B6YzkznMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q7Z7A3 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-15741880|ensembl:ENSP00000390011|uniprotkb:A8K558|uniprotkb:Q96GZ7 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:ctu1_human(display_long)|uniprotkb:CTU1(gene name)|psi-mi:CTU1(display_short)|uniprotkb:ATPBD3(gene name synonym)|uniprotkb:NCS6(gene name synonym)|uniprotkb:ATP-binding domain-containing protein 3(gene name synonym)|uniprotkb:Cancer-associated gene protein(gene name synonym)|uniprotkb:Cytoplasmic tRNA adenylyltransferase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902685|imex:IM-21221-2|dip:DIP-191135E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N ensembl:ENSG00000142544(gene)|ensembl:ENST00000421832(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0002144"(cytosolic tRNA wobble base thiouridylase complex)|go:"GO:0005829"(cytosol)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|interpro:IPR000541(Protein of unknown function UPF0021)|interpro:IPR011063(PP-loop)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR032442|interpro:IPR035107|reactome:R-HSA-6782315|refseq:NP_660275.2|dip:DIP-48632N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:yxwQuNF8CQyvLulvdC/4pVFtQCU9606 rigid:aoXSiy7mySK3+iDW2+B6YzkznMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9Y4E8 uniprotkb:Q9BTM9 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15902666|imex:IM-21221-1|dip:DIP-191139E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rigid:leeqWyIZfffVJUuZAHoyG+7B3pI false - ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-4399559 uniprotkb:P40818 dip:DIP-24261N intact:EBI-1050865|uniprotkb:Q2TB31|uniprotkb:Q7Z3U2|uniprotkb:Q86VA0|uniprotkb:Q8IWI7|ensembl:ENSP00000302239|ensembl:ENSP00000379721|uniprotkb:B4DKA8 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:ubp8_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:USP8(gene name)|psi-mi:USP8(display_short)|uniprotkb:KIAA0055(gene name synonym)|uniprotkb:UBPY(gene name synonym)|uniprotkb:Ubiquitin isopeptidase Y(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym) psi-mi:"MI:0998"(deubiquitinase assay) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0204"(deubiquitination reaction) psi-mi:"MI:0465"(DIP) intact:EBI-15902735|imex:IM-21221-4|dip:DIP-191141E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 refseq:NP_001122082.1|refseq:NP_005145.3|refseq:NP_001269978.1|refseq:XP_011520495.1|ensembl:ENSG00000138592(gene)|ensembl:ENST00000307179(transcript)|ensembl:ENST00000396444(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0045296"(cadherin binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|mint:P40818|rcsb pdb:1WHB|rcsb pdb:2A9U|rcsb pdb:2GFO|rcsb pdb:2GWF|rcsb pdb:3N3K|rcsb pdb:6F09|reactome:R-HSA-1358803|reactome:R-HSA-4641263|reactome:R-HSA-5689880|reactome:R-HSA-6807004|refseq:XP_006720824.1|dip:DIP-40365N psi-mi:"MI:0465"(dip) no-uniprot-update: - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:hpBBzyA4lc9is80ZFJBr1fyEyOM9606 rigid:KfO4cj/oA5I1u5MPnRCgGL80qOw false aminomethylcoumarin label:0-0 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z7A3 uniprotkb:Q9BTM9 intact:EBI-15741880|ensembl:ENSP00000390011|uniprotkb:A8K558|uniprotkb:Q96GZ7 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 psi-mi:ctu1_human(display_long)|uniprotkb:CTU1(gene name)|psi-mi:CTU1(display_short)|uniprotkb:ATPBD3(gene name synonym)|uniprotkb:NCS6(gene name synonym)|uniprotkb:ATP-binding domain-containing protein 3(gene name synonym)|uniprotkb:Cancer-associated gene protein(gene name synonym)|uniprotkb:Cytoplasmic tRNA adenylyltransferase 1(gene name synonym) psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15902714|imex:IM-21221-3|dip:DIP-103328E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000142544(gene)|ensembl:ENST00000421832(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0002144"(cytosolic tRNA wobble base thiouridylase complex)|go:"GO:0005829"(cytosol)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|interpro:IPR000541(Protein of unknown function UPF0021)|interpro:IPR011063(PP-loop)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR032442|interpro:IPR035107|reactome:R-HSA-6782315|refseq:NP_660275.2|dip:DIP-48632N ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:yxwQuNF8CQyvLulvdC/4pVFtQCU9606 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rigid:xTduKy41LpvPN+KHDVQWGAZuIQU false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95396 uniprotkb:Q9BTM9 intact:EBI-373206|ensembl:ENSP00000244051 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 psi-mi:mocs3_human(display_long)|uniprotkb:MOCS3(gene name)|psi-mi:MOCS3(display_short)|uniprotkb:Molybdopterin synthase sulfurylase(gene name synonym)|uniprotkb:UBA4(gene name synonym)|uniprotkb:Molybdenum cofactor synthesis protein 3(gene name synonym) psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0195"(covalent binding) psi-mi:"MI:0465"(DIP) intact:EBI-15902754|imex:IM-21221-5|dip:DIP-191137E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055299.1|ensembl:ENSG00000124217(gene)|ensembl:ENST00000244051(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0042292"(URM1 activating enzyme activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0061604"(molybdopterin-synthase sulfurtransferase activity)|go:"GO:0061605"(molybdopterin-synthase adenylyltransferase activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR001763(Rhodanese-like)|interpro:IPR028885|interpro:IPR035985|interpro:IPR036873|rcsb pdb:3I2V|reactome:R-HSA-947581|dip:DIP-31168N ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:yIgGuZAL6kHczqsQriXyJBa3fGQ9606 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rigid:fXzpnSxNEL1Q+EcklbTgjT48e4A false - ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2VPK5 uniprotkb:Q9BTM9 intact:EBI-15741930|ensembl:ENSP00000388320|uniprotkb:B2RXK0|uniprotkb:Q0P511|uniprotkb:Q66K78|uniprotkb:Q6P4C8|uniprotkb:Q86SV4 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 psi-mi:ctu2_human(display_long)|uniprotkb:CTU2(gene name)|psi-mi:CTU2(display_short)|uniprotkb:C16orf84(gene name synonym)|uniprotkb:NCS2(gene name synonym)|uniprotkb:Cytosolic thiouridylase subunit 2(gene name synonym) psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15902773|imex:IM-21221-6|dip:DIP-191138E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000174177(gene)|ensembl:ENST00000453996(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0005829"(cytosol)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034227"(tRNA thio-modification)|interpro:IPR019407|reactome:R-HSA-6782315|refseq:NP_001012777.1|refseq:NP_001012780.1|refseq:NP_001305436.1|refseq:NP_001305442.1|dip:DIP-48633N ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:Hinc7cYz796nchVLZ3s32zG2mxY9606 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rigid:wrCCf39EXeZePwN8iBrs73XailQ false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55060 uniprotkb:Q9BTM9 intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym) psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15902794|imex:IM-21221-7|dip:DIP-191140E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060 ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rigid:fQDt19HWtbgOX9OaaegMtp+exMM false - ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y4E8 intact:EBI-4399559 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 dip:DIP-24261N psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0998"(deubiquitinase assay) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0204"(deubiquitination reaction) psi-mi:"MI:0465"(DIP) intact:EBI-15902813|imex:IM-21221-8|dip:DIP-191142E - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/15 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:60F6+1Z8gKcxQ4CM8/L41dJlS/Y false - aminomethylcoumarin label:0-0 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BTM9 uniprotkb:P16152 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-351348|uniprotkb:Q3LHW8|uniprotkb:B2RBZ7|ensembl:ENSP00000290349|uniprotkb:B4DFK7 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:cbr1_human(display_long)|uniprotkb:SDR21C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 21C member 1(gene name synonym)|uniprotkb:CBR1(gene name)|psi-mi:CBR1(display_short)|uniprotkb:CBR(gene name synonym)|uniprotkb:CRN(gene name synonym)|uniprotkb:NADPH-dependent carbonyl reductase 1(gene name synonym)|uniprotkb:"Prostaglandin-E(2) 9-reductase"(gene name synonym)|uniprotkb:Prostaglandin 9-ketoreductase(gene name synonym)|uniprotkb:"15-hydroxyprostaglandin dehydrogenase [NADP(+)]"(gene name synonym)|uniprotkb:20-beta-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_001748.1|ensembl:ENSG00000159228(gene)|ensembl:ENST00000290349(transcript)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005829"(cytosol)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0017144"|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042373"(vitamin K metabolic process)|go:"GO:0047020"("15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity")|go:"GO:0047021"("15-hydroxyprostaglandin dehydrogenase (NADP+) activity")|go:"GO:0050221"(prostaglandin-E2 9-reductase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P16152|rcsb pdb:1WMA|rcsb pdb:2PFG|rcsb pdb:3BHI|rcsb pdb:3BHJ|rcsb pdb:3BHM|rcsb pdb:4Z3D|reactome:R-HSA-2162123|refseq:NP_001273718.1|dip:DIP-33136N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:ROzNiYne9nXfvDC9Hi3Ni6M7ILA9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:P26196 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q8NC51 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:O95163 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-347559|uniprotkb:Q9H327|uniprotkb:Q9UG87|uniprotkb:Q5JSV2|ensembl:ENSP00000363779|ensembl:ENSP00000501893 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:elp1_human(display_long)|uniprotkb:ELP1(gene name)|psi-mi:ELP1(display_short)|uniprotkb:IKAP(gene name synonym)|uniprotkb:IKBKAP(gene name synonym)|uniprotkb:p150(gene name synonym)|uniprotkb:IkappaB kinase complex-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N dip:DIP-27579N|refseq:NP_003631.2|refseq:NP_001305289.1|ensembl:ENSG00000070061(gene)|ensembl:ENST00000374647(transcript)|ensembl:ENST00000675406(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR006849(IKI3)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:O95163|rcsb pdb:5CQR|reactome:R-HSA-3214847|go:"GO:0005829"(cytosol) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:hl+inV6TcN+DGu9CwE3SitkHiI09606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q08J23 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-1642839|intact:EBI-2839052|uniprotkb:A8K529|uniprotkb:B3KP09|uniprotkb:G3V1R4|uniprotkb:Q9BVN4|uniprotkb:Q9H858|uniprotkb:Q9NXD9|uniprotkb:B2RNR4|intact:EBI-2556652|uniprotkb:B4DQW2|ensembl:ENSP00000264670 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:nsun2_human(display_long)|uniprotkb:NSUN2(gene name)|psi-mi:NSUN2(display_short)|uniprotkb:SAKI(gene name synonym)|uniprotkb:TRM4(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 2(gene name synonym)|uniprotkb:tRNA methyltransferase 4 homolog(gene name synonym)|uniprotkb:Substrate of AIM1/Aurora kinase B(gene name synonym)|uniprotkb:Myc-induced SUN domain-containing protein(gene name synonym)|uniprotkb:"mRNA cytosine C(5)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA cytosine C(5)-methyltransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_001180384.1|refseq:NP_060225.4|dip:DIP-52456N|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006400"(tRNA modification)|go:"GO:0007286"(spermatid development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016428"("tRNA (cytosine-5-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0033313"(meiotic cell cycle checkpoint signaling)|go:"GO:0033391"(chromatoid body)|go:"GO:0036416"(tRNA stabilization)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051301"(cell division)|go:"GO:0062152"("mRNA (cytidine-5-)-methyltransferase activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR023270|interpro:IPR029063|mint:Q08J23|reactome:R-HSA-6782315|ensembl:ENSG00000037474(gene)|ensembl:ENST00000264670(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001510"(RNA methylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:k3hK/9cjuy5c4PyDGgCt0LsVtdo9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q12769 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-295715|uniprotkb:Q96GB3|uniprotkb:Q9H660|uniprotkb:B4DYE8|uniprotkb:B4E2J9|uniprotkb:Q08AD3|uniprotkb:Q7Z5X6|intact:EBI-2563140|ensembl:ENSP00000367721 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:nu160_human(display_long)|uniprotkb:NUP160(gene name)|psi-mi:NUP160(display_short)|uniprotkb:KIAA0197(gene name synonym)|uniprotkb:NUP120(gene name synonym)|uniprotkb:Nucleoporin Nup160(gene name synonym)|uniprotkb:160 kDa nucleoporin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_056046.1|refseq:NP_001305328.1|dip:DIP-31262N|ensembl:ENSG00000030066(gene)|ensembl:ENST00000378460(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0072006"(nephron development)|interpro:IPR021717|mint:Q12769|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:15tRpv4+wvw31oJPxM42NxWdRUc9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q9UBU9 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:P46060 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:P55060 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q5VTR2 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-2372238|uniprotkb:Q2TB34|uniprotkb:Q69YL5|uniprotkb:Q6P527|uniprotkb:Q8N3J4|uniprotkb:Q96JD3|uniprotkb:Q9H9Y7|uniprotkb:Q9HA51|uniprotkb:Q9NUR4|uniprotkb:Q9NWQ3|uniprotkb:Q9NX83|uniprotkb:A7MCT5|ensembl:ENSP00000373772 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:bre1a_human(display_long)|uniprotkb:RNF20(gene name)|psi-mi:RNF20(display_short)|uniprotkb:BRE1A(gene name synonym)|uniprotkb:RING finger protein 20(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:XP_011517164.1|refseq:NP_062538.5|dip:DIP-53411N|ensembl:ENSG00000155827(gene)|ensembl:ENST00000389120(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|interpro:IPR017907|mint:Q5VTR2|rcsb pdb:5TRB|reactome:R-HSA-8866654|reactome:R-HSA-9013422 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:zscBhEtpu0D69sPn1wXsEGBIiOY9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q96K76 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-2514143|ensembl:ENSP00000382382|uniprotkb:Q86Y73|uniprotkb:Q9NWN1|uniprotkb:Q9BWI0|uniprotkb:Q8TEP6|uniprotkb:Q658U0|intact:EBI-11020736|uniprotkb:B3KXF5|uniprotkb:E9PM46 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:ubp47_human(display_long)|uniprotkb:USP47(gene name)|psi-mi:USP47(display_short)|uniprotkb:Ubiquitin-specific-processing protease 47(gene name synonym)|uniprotkb:Deubiquitinating enzyme 47(gene name synonym)|uniprotkb:Ubiquitin thioesterase 47(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_001269588.1|ensembl:ENSG00000170242(gene)|ensembl:ENST00000399455(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR029071|interpro:IPR038765|mint:Q96K76|reactome:R-HSA-5689880|refseq:NP_001317137.1|refseq:NP_060414.3|dip:DIP-53629N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:XPhYwHpj4bDPhA/uMESoVswI6Jo9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q9Y4E8 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:O95396 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-373206|ensembl:ENSP00000244051 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:mocs3_human(display_long)|uniprotkb:MOCS3(gene name)|psi-mi:MOCS3(display_short)|uniprotkb:Molybdopterin synthase sulfurylase(gene name synonym)|uniprotkb:UBA4(gene name synonym)|uniprotkb:Molybdenum cofactor synthesis protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N refseq:NP_055299.1|ensembl:ENSG00000124217(gene)|ensembl:ENST00000244051(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0042292"(URM1 activating enzyme activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0061604"(molybdopterin-synthase sulfurtransferase activity)|go:"GO:0061605"(molybdopterin-synthase adenylyltransferase activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR001763(Rhodanese-like)|interpro:IPR028885|interpro:IPR035985|interpro:IPR036873|rcsb pdb:3I2V|reactome:R-HSA-947581|dip:DIP-31168N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:yIgGuZAL6kHczqsQriXyJBa3fGQ9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9BTM9 uniprotkb:Q7Z7A3 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 intact:EBI-15741880|ensembl:ENSP00000390011|uniprotkb:A8K558|uniprotkb:Q96GZ7 psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:ctu1_human(display_long)|uniprotkb:CTU1(gene name)|psi-mi:CTU1(display_short)|uniprotkb:ATPBD3(gene name synonym)|uniprotkb:NCS6(gene name synonym)|uniprotkb:ATP-binding domain-containing protein 3(gene name synonym)|uniprotkb:Cancer-associated gene protein(gene name synonym)|uniprotkb:Cytoplasmic tRNA adenylyltransferase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15902832|imex:IM-21221-9|dip:DIP-191136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N ensembl:ENSG00000142544(gene)|ensembl:ENST00000421832(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0002144"(cytosolic tRNA wobble base thiouridylase complex)|go:"GO:0005829"(cytosol)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|interpro:IPR000541(Protein of unknown function UPF0021)|interpro:IPR011063(PP-loop)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR032442|interpro:IPR035107|reactome:R-HSA-6782315|refseq:NP_660275.2|dip:DIP-48632N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rogid:yxwQuNF8CQyvLulvdC/4pVFtQCU9606 rigid:R1cNqNZo4mqumGUyMAJaVn7aLMo false ha tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O95396 uniprotkb:Q9BTM9 intact:EBI-373206|ensembl:ENSP00000244051 intact:EBI-714589|ensembl:ENSP00000361944|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4 psi-mi:mocs3_human(display_long)|uniprotkb:MOCS3(gene name)|psi-mi:MOCS3(display_short)|uniprotkb:Molybdopterin synthase sulfurylase(gene name synonym)|uniprotkb:UBA4(gene name synonym)|uniprotkb:Molybdenum cofactor synthesis protein 3(gene name synonym) psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15902864|imex:IM-21221-10|dip:DIP-191137E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055299.1|ensembl:ENSG00000124217(gene)|ensembl:ENST00000244051(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0042292"(URM1 activating enzyme activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0061604"(molybdopterin-synthase sulfurtransferase activity)|go:"GO:0061605"(molybdopterin-synthase adenylyltransferase activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR001763(Rhodanese-like)|interpro:IPR028885|interpro:IPR035985|interpro:IPR036873|rcsb pdb:3I2V|reactome:R-HSA-947581|dip:DIP-31168N ensembl:ENSG00000167118(gene)|ensembl:ENST00000372853(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|dip:DIP-48631N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:yIgGuZAL6kHczqsQriXyJBa3fGQ9606 rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606 rigid:fXzpnSxNEL1Q+EcklbTgjT48e4A false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22314 intact:EBI-4399559 intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568 dip:DIP-24261N psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0808"(comigration in sds page) Van et al. (2011) pubmed:21209336|doi:10.1073/pnas.1014402108|imex:IM-21221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0195"(covalent binding) psi-mi:"MI:0465"(DIP) intact:EBI-15902885|imex:IM-21221-11|dip:DIP-191143E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168 uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/15 rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:8SxOU4MV/2jEAwcW1vcZ6hG9eAw false - glutathione s tranferase tag:0-0 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)