#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-15896509	uniprotkb:P47811	dip:DIP-59046N	intact:EBI-298727|ensembl:ENSMUSP00000061958|uniprotkb:O08666|uniprotkb:Q3U6R5|uniprotkb:Q3UZS3|uniprotkb:Q8C289|uniprotkb:Q9JLV8|uniprotkb:Q9QZ80|uniprotkb:B2KF37|uniprotkb:B2KF38	psi-mi:pepmek3b(display_short)|psi-mi:EBI-15896509(display_long)	psi-mi:mk14_mouse(display_long)|uniprotkb:Mapk14(gene name)|psi-mi:Mapk14(display_short)|uniprotkb:Crk1(gene name synonym)|uniprotkb:Csbp1(gene name synonym)|uniprotkb:Csbp2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase p38 alpha(gene name synonym)|uniprotkb:CRK1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Akella et al. (2010)	pubmed:21134636|doi:10.1016/j.str.2010.09.015|imex:IM-16059	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15896512|imex:IM-16059-1|dip:DIP-186909E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	reactome:R-MMU-4420097|reactome:R-MMU-450302|reactome:R-MMU-450341|reactome:R-MMU-525793|reactome:R-MMU-5668599|reactome:R-MMU-6798695|reactome:R-MMU-6804756|ensembl:ENSMUSG00000053436(gene)|ensembl:ENSMUST00000062694(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000922"(spindle pole)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001890"(placenta development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016301"(kinase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|rcsb pdb:1LEZ|rcsb pdb:1YW2|rcsb pdb:1YWR|rcsb pdb:2EWA|rcsb pdb:2GHL|rcsb pdb:2GHM|rcsb pdb:2GTM|rcsb pdb:2GTN|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099179"(regulation of synaptic membrane adhesion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038784|mint:P47811|rcsb pdb:1LEW|rcsb pdb:5R9F|rcsb pdb:5R9G|rcsb pdb:5R9H|rcsb pdb:5R9I|rcsb pdb:2OZA|rcsb pdb:2PUU|rcsb pdb:3P4K|rcsb pdb:3P5K|rcsb pdb:3P78|rcsb pdb:3P79|rcsb pdb:3P7A|rcsb pdb:3P7B|rcsb pdb:3P7C|rcsb pdb:3PY3|rcsb pdb:3TG1|rcsb pdb:4KA3|rcsb pdb:4LOO|rcsb pdb:4LOP|rcsb pdb:4LOQ|rcsb pdb:4TYH|rcsb pdb:5LAR|rcsb pdb:5NZZ|rcsb pdb:5O90|rcsb pdb:5R8U|rcsb pdb:5R8V|rcsb pdb:5R8W|rcsb pdb:5R8X|rcsb pdb:5R8Y|rcsb pdb:5R8Z|rcsb pdb:5R90|rcsb pdb:5R91|rcsb pdb:5R92|rcsb pdb:5R93|rcsb pdb:5R94|rcsb pdb:5R95|rcsb pdb:5R96|rcsb pdb:5R97|rcsb pdb:5R98|rcsb pdb:5R99|rcsb pdb:5R9A|rcsb pdb:5R9B|rcsb pdb:5R9C|rcsb pdb:5R9D|rcsb pdb:5R9E|rcsb pdb:5R9J|rcsb pdb:5R9K|rcsb pdb:5R9L|rcsb pdb:5R9M|rcsb pdb:5R9N|rcsb pdb:5R9O|rcsb pdb:5R9P|rcsb pdb:5R9Q|rcsb pdb:5R9R|rcsb pdb:5R9S|rcsb pdb:5R9T|rcsb pdb:5R9U|rcsb pdb:5R9V|rcsb pdb:5R9W|rcsb pdb:5R9X|rcsb pdb:5R9Y|rcsb pdb:5R9Z|rcsb pdb:5RA0|rcsb pdb:5RA1|rcsb pdb:5RA2|rcsb pdb:5RA3|rcsb pdb:5RA4|rcsb pdb:5RA5|rcsb pdb:5RA6|rcsb pdb:5RA7|rcsb pdb:5RA8|rcsb pdb:5RA9|rcsb pdb:5UOJ|rcsb pdb:6SO1|rcsb pdb:6SO2|rcsb pdb:6SO4|rcsb pdb:6SOD|rcsb pdb:6SOI|rcsb pdb:6SOT|rcsb pdb:6SOU|rcsb pdb:6SOV|rcsb pdb:6SP9|rcsb pdb:6SPL|rcsb pdb:6Y4T|rcsb pdb:6Y4U|rcsb pdb:6Y4V|rcsb pdb:6Y4W|rcsb pdb:6Y4X|rcsb pdb:6Y6V|rcsb pdb:6Y7W|rcsb pdb:6Y7X|rcsb pdb:6Y7Y|rcsb pdb:6Y7Z|rcsb pdb:6Y80|rcsb pdb:6Y81|rcsb pdb:6Y82|rcsb pdb:6Y85|rcsb pdb:6Y8H|rcsb pdb:6YCU|rcsb pdb:6YCW|rcsb pdb:6YJC|rcsb pdb:6YK7|rcsb pdb:6ZWR|rcsb pdb:7BDO|rcsb pdb:7BDQ|rcsb pdb:7BE4|rcsb pdb:7BE5|reactome:R-MMU-168638|reactome:R-MMU-171007|reactome:R-MMU-198753|reactome:R-MMU-2559580|reactome:R-MMU-376172|reactome:R-MMU-418592|reactome:R-MMU-432142|refseq:NP_001161980.1|refseq:NP_001161985.1|refseq:NP_001161986.1|refseq:NP_036081.1|dip:DIP-31073N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:xdIc2tB6JutXOqK3rZgxlVC8jho-2	rogid:ks/9pIKb9SsZnYW71qj+5v5GVaw10090	rigid:4v0R4zPG6JvfYinQDgRML6IIFs8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-15896509	uniprotkb:P47811	dip:DIP-59046N	intact:EBI-298727|ensembl:ENSMUSP00000061958|uniprotkb:O08666|uniprotkb:Q3U6R5|uniprotkb:Q3UZS3|uniprotkb:Q8C289|uniprotkb:Q9JLV8|uniprotkb:Q9QZ80|uniprotkb:B2KF37|uniprotkb:B2KF38	psi-mi:pepmek3b(display_short)|psi-mi:EBI-15896509(display_long)	psi-mi:mk14_mouse(display_long)|uniprotkb:Mapk14(gene name)|psi-mi:Mapk14(display_short)|uniprotkb:Crk1(gene name synonym)|uniprotkb:Csbp1(gene name synonym)|uniprotkb:Csbp2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase p38 alpha(gene name synonym)|uniprotkb:CRK1(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Akella et al. (2010)	pubmed:21134636|doi:10.1016/j.str.2010.09.015|imex:IM-16059	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15896529|imex:IM-16059-2|dip:DIP-186909E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	reactome:R-MMU-4420097|reactome:R-MMU-450302|reactome:R-MMU-450341|reactome:R-MMU-525793|reactome:R-MMU-5668599|reactome:R-MMU-6798695|reactome:R-MMU-6804756|ensembl:ENSMUSG00000053436(gene)|ensembl:ENSMUST00000062694(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000922"(spindle pole)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001890"(placenta development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016301"(kinase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|rcsb pdb:1LEZ|rcsb pdb:1YW2|rcsb pdb:1YWR|rcsb pdb:2EWA|rcsb pdb:2GHL|rcsb pdb:2GHM|rcsb pdb:2GTM|rcsb pdb:2GTN|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099179"(regulation of synaptic membrane adhesion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038784|mint:P47811|rcsb pdb:1LEW|rcsb pdb:5R9F|rcsb pdb:5R9G|rcsb pdb:5R9H|rcsb pdb:5R9I|rcsb pdb:2OZA|rcsb pdb:2PUU|rcsb pdb:3P4K|rcsb pdb:3P5K|rcsb pdb:3P78|rcsb pdb:3P79|rcsb pdb:3P7A|rcsb pdb:3P7B|rcsb pdb:3P7C|rcsb pdb:3PY3|rcsb pdb:3TG1|rcsb pdb:4KA3|rcsb pdb:4LOO|rcsb pdb:4LOP|rcsb pdb:4LOQ|rcsb pdb:4TYH|rcsb pdb:5LAR|rcsb pdb:5NZZ|rcsb pdb:5O90|rcsb pdb:5R8U|rcsb pdb:5R8V|rcsb pdb:5R8W|rcsb pdb:5R8X|rcsb pdb:5R8Y|rcsb pdb:5R8Z|rcsb pdb:5R90|rcsb pdb:5R91|rcsb pdb:5R92|rcsb pdb:5R93|rcsb pdb:5R94|rcsb pdb:5R95|rcsb pdb:5R96|rcsb pdb:5R97|rcsb pdb:5R98|rcsb pdb:5R99|rcsb pdb:5R9A|rcsb pdb:5R9B|rcsb pdb:5R9C|rcsb pdb:5R9D|rcsb pdb:5R9E|rcsb pdb:5R9J|rcsb pdb:5R9K|rcsb pdb:5R9L|rcsb pdb:5R9M|rcsb pdb:5R9N|rcsb pdb:5R9O|rcsb pdb:5R9P|rcsb pdb:5R9Q|rcsb pdb:5R9R|rcsb pdb:5R9S|rcsb pdb:5R9T|rcsb pdb:5R9U|rcsb pdb:5R9V|rcsb pdb:5R9W|rcsb pdb:5R9X|rcsb pdb:5R9Y|rcsb pdb:5R9Z|rcsb pdb:5RA0|rcsb pdb:5RA1|rcsb pdb:5RA2|rcsb pdb:5RA3|rcsb pdb:5RA4|rcsb pdb:5RA5|rcsb pdb:5RA6|rcsb pdb:5RA7|rcsb pdb:5RA8|rcsb pdb:5RA9|rcsb pdb:5UOJ|rcsb pdb:6SO1|rcsb pdb:6SO2|rcsb pdb:6SO4|rcsb pdb:6SOD|rcsb pdb:6SOI|rcsb pdb:6SOT|rcsb pdb:6SOU|rcsb pdb:6SOV|rcsb pdb:6SP9|rcsb pdb:6SPL|rcsb pdb:6Y4T|rcsb pdb:6Y4U|rcsb pdb:6Y4V|rcsb pdb:6Y4W|rcsb pdb:6Y4X|rcsb pdb:6Y6V|rcsb pdb:6Y7W|rcsb pdb:6Y7X|rcsb pdb:6Y7Y|rcsb pdb:6Y7Z|rcsb pdb:6Y80|rcsb pdb:6Y81|rcsb pdb:6Y82|rcsb pdb:6Y85|rcsb pdb:6Y8H|rcsb pdb:6YCU|rcsb pdb:6YCW|rcsb pdb:6YJC|rcsb pdb:6YK7|rcsb pdb:6ZWR|rcsb pdb:7BDO|rcsb pdb:7BDQ|rcsb pdb:7BE4|rcsb pdb:7BE5|reactome:R-MMU-168638|reactome:R-MMU-171007|reactome:R-MMU-198753|reactome:R-MMU-2559580|reactome:R-MMU-376172|reactome:R-MMU-418592|reactome:R-MMU-432142|refseq:NP_001161980.1|refseq:NP_001161985.1|refseq:NP_001161986.1|refseq:NP_036081.1|dip:DIP-31073N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:xdIc2tB6JutXOqK3rZgxlVC8jho-2	rogid:ks/9pIKb9SsZnYW71qj+5v5GVaw10090	rigid:4v0R4zPG6JvfYinQDgRML6IIFs8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)