#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P51534 uniprotkb:P51534 intact:EBI-17086|ensemblfungi:YOR035C|uniprotkb:D6W2A2 intact:EBI-17086|ensemblfungi:YOR035C|uniprotkb:D6W2A2 psi-mi:she4_yeast(display_long)|uniprotkb:OR26.26(orf name)|uniprotkb:YOR035C(locus name)|uniprotkb:SHE4(gene name)|psi-mi:SHE4(display_short) psi-mi:she4_yeast(display_long)|uniprotkb:OR26.26(orf name)|uniprotkb:YOR035C(locus name)|uniprotkb:SHE4(gene name)|psi-mi:SHE4(display_short) psi-mi:"MI:0114"(x-ray crystallography) Shi et al. (2010) pubmed:21115842|doi:10.1073/pnas.1013038107|imex:IM-17150 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15895369|imex:IM-17150-1|dip:DIP-188147E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014678.1|sgd:S000005561|ensemblfungi:YOR035C(gene)|ensemblfungi:YOR035C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017022"(myosin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024660|rcsb pdb:3OPB|dip:DIP-4186N|mint:P51534 refseq:NP_014678.1|sgd:S000005561|ensemblfungi:YOR035C(gene)|ensemblfungi:YOR035C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017022"(myosin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024660|rcsb pdb:3OPB|dip:DIP-4186N|mint:P51534 psi-mi:"MI:0465"(dip) crc64:4A0E1C7D41939B44 crc64:4A0E1C7D41939B44 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:aahihUKRvHF7B8fqhzg2XIO1tpc559292 rogid:aahihUKRvHF7B8fqhzg2XIO1tpc559292 rigid:lvN5snnVFId7XRy//zVJwIRv2z0 false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51534 uniprotkb:P51534 intact:EBI-17086|ensemblfungi:YOR035C|uniprotkb:D6W2A2 intact:EBI-17086|ensemblfungi:YOR035C|uniprotkb:D6W2A2 psi-mi:she4_yeast(display_long)|uniprotkb:OR26.26(orf name)|uniprotkb:YOR035C(locus name)|uniprotkb:SHE4(gene name)|psi-mi:SHE4(display_short) psi-mi:she4_yeast(display_long)|uniprotkb:OR26.26(orf name)|uniprotkb:YOR035C(locus name)|uniprotkb:SHE4(gene name)|psi-mi:SHE4(display_short) psi-mi:"MI:0071"(molecular sieving) Shi et al. (2010) pubmed:21115842|doi:10.1073/pnas.1013038107|imex:IM-17150 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15895385|imex:IM-17150-2|dip:DIP-188147E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014678.1|sgd:S000005561|ensemblfungi:YOR035C(gene)|ensemblfungi:YOR035C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017022"(myosin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024660|rcsb pdb:3OPB|dip:DIP-4186N|mint:P51534 refseq:NP_014678.1|sgd:S000005561|ensemblfungi:YOR035C(gene)|ensemblfungi:YOR035C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017022"(myosin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024660|rcsb pdb:3OPB|dip:DIP-4186N|mint:P51534 psi-mi:"MI:0465"(dip) crc64:4A0E1C7D41939B44 crc64:4A0E1C7D41939B44 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:aahihUKRvHF7B8fqhzg2XIO1tpc559292 rogid:aahihUKRvHF7B8fqhzg2XIO1tpc559292 rigid:lvN5snnVFId7XRy//zVJwIRv2z0 false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32492 uniprotkb:P51534 intact:EBI-11681|ensemblfungi:YAL029C|uniprotkb:D6VPI9 intact:EBI-17086|ensemblfungi:YOR035C|uniprotkb:D6W2A2 psi-mi:myo4_yeast(display_long)|uniprotkb:MYO4(gene name)|psi-mi:MYO4(display_short)|uniprotkb:SHE1(gene name synonym)|uniprotkb:YAL029C(locus name)|uniprotkb:FUN22(orf name)|uniprotkb:SWI5-dependent HO expression protein 1(gene name synonym) psi-mi:she4_yeast(display_long)|uniprotkb:OR26.26(orf name)|uniprotkb:YOR035C(locus name)|uniprotkb:SHE4(gene name)|psi-mi:SHE4(display_short) psi-mi:"MI:0096"(pull down) Shi et al. (2010) pubmed:21115842|doi:10.1073/pnas.1013038107|imex:IM-17150 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15895401|imex:IM-17150-3|dip:DIP-188148E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007015"(actin filament organization)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|rcsb pdb:3MMI|rcsb pdb:4LL6|rcsb pdb:4LL8|reactome:R-SCE-190873|reactome:R-SCE-9013419|reactome:R-SCE-9013425|ensemblfungi:YAL029C(gene)|ensemblfungi:YAL029C_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|refseq:NP_009373.1|sgd:S000000027|mint:P32492|dip:DIP-5761N refseq:NP_014678.1|sgd:S000005561|ensemblfungi:YOR035C(gene)|ensemblfungi:YOR035C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017022"(myosin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024660|rcsb pdb:3OPB|dip:DIP-4186N|mint:P51534 psi-mi:"MI:0465"(dip) crc64:E79C0FE72B041E95 crc64:4A0E1C7D41939B44 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:jxx/cStiu7zpcGFLmoTedhHVZcY559292 rogid:aahihUKRvHF7B8fqhzg2XIO1tpc559292 rigid:gaZny7uYVZXlpzBzSRFCnllszRQ false sufficient binding region:561-587|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P51534 uniprotkb:P51534 intact:EBI-17086|ensemblfungi:YOR035C|uniprotkb:D6W2A2 intact:EBI-17086|ensemblfungi:YOR035C|uniprotkb:D6W2A2 psi-mi:she4_yeast(display_long)|uniprotkb:OR26.26(orf name)|uniprotkb:YOR035C(locus name)|uniprotkb:SHE4(gene name)|psi-mi:SHE4(display_short) psi-mi:she4_yeast(display_long)|uniprotkb:OR26.26(orf name)|uniprotkb:YOR035C(locus name)|uniprotkb:SHE4(gene name)|psi-mi:SHE4(display_short) psi-mi:"MI:0067"(light scattering) Shi et al. (2010) pubmed:21115842|doi:10.1073/pnas.1013038107|imex:IM-17150 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15895422|imex:IM-17150-4|dip:DIP-188147E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014678.1|sgd:S000005561|ensemblfungi:YOR035C(gene)|ensemblfungi:YOR035C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017022"(myosin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024660|rcsb pdb:3OPB|dip:DIP-4186N|mint:P51534 refseq:NP_014678.1|sgd:S000005561|ensemblfungi:YOR035C(gene)|ensemblfungi:YOR035C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017022"(myosin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024660|rcsb pdb:3OPB|dip:DIP-4186N|mint:P51534 psi-mi:"MI:0465"(dip) crc64:4A0E1C7D41939B44 crc64:4A0E1C7D41939B44 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:aahihUKRvHF7B8fqhzg2XIO1tpc559292 rogid:aahihUKRvHF7B8fqhzg2XIO1tpc559292 rigid:lvN5snnVFId7XRy//zVJwIRv2z0 false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32492 uniprotkb:P51534 intact:EBI-11681|ensemblfungi:YAL029C|uniprotkb:D6VPI9 intact:EBI-17086|ensemblfungi:YOR035C|uniprotkb:D6W2A2 psi-mi:myo4_yeast(display_long)|uniprotkb:MYO4(gene name)|psi-mi:MYO4(display_short)|uniprotkb:SHE1(gene name synonym)|uniprotkb:YAL029C(locus name)|uniprotkb:FUN22(orf name)|uniprotkb:SWI5-dependent HO expression protein 1(gene name synonym) psi-mi:she4_yeast(display_long)|uniprotkb:OR26.26(orf name)|uniprotkb:YOR035C(locus name)|uniprotkb:SHE4(gene name)|psi-mi:SHE4(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Shi et al. (2010) pubmed:21115842|doi:10.1073/pnas.1013038107|imex:IM-17150 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15895438|imex:IM-17150-5|dip:DIP-188148E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007015"(actin filament organization)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|rcsb pdb:3MMI|rcsb pdb:4LL6|rcsb pdb:4LL8|reactome:R-SCE-190873|reactome:R-SCE-9013419|reactome:R-SCE-9013425|ensemblfungi:YAL029C(gene)|ensemblfungi:YAL029C_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|refseq:NP_009373.1|sgd:S000000027|mint:P32492|dip:DIP-5761N refseq:NP_014678.1|sgd:S000005561|ensemblfungi:YOR035C(gene)|ensemblfungi:YOR035C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017022"(myosin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024660|rcsb pdb:3OPB|dip:DIP-4186N|mint:P51534 psi-mi:"MI:0465"(dip) crc64:E79C0FE72B041E95 crc64:4A0E1C7D41939B44 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:jxx/cStiu7zpcGFLmoTedhHVZcY559292 rogid:aahihUKRvHF7B8fqhzg2XIO1tpc559292 rigid:gaZny7uYVZXlpzBzSRFCnllszRQ false binding-associated region:561-587 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32492 uniprotkb:P51534 intact:EBI-11681|ensemblfungi:YAL029C|uniprotkb:D6VPI9 intact:EBI-17086|ensemblfungi:YOR035C|uniprotkb:D6W2A2 psi-mi:myo4_yeast(display_long)|uniprotkb:MYO4(gene name)|psi-mi:MYO4(display_short)|uniprotkb:SHE1(gene name synonym)|uniprotkb:YAL029C(locus name)|uniprotkb:FUN22(orf name)|uniprotkb:SWI5-dependent HO expression protein 1(gene name synonym) psi-mi:she4_yeast(display_long)|uniprotkb:OR26.26(orf name)|uniprotkb:YOR035C(locus name)|uniprotkb:SHE4(gene name)|psi-mi:SHE4(display_short) psi-mi:"MI:0096"(pull down) Shi et al. (2010) pubmed:21115842|doi:10.1073/pnas.1013038107|imex:IM-17150 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15895457|imex:IM-17150-6|dip:DIP-188148E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007015"(actin filament organization)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|rcsb pdb:3MMI|rcsb pdb:4LL6|rcsb pdb:4LL8|reactome:R-SCE-190873|reactome:R-SCE-9013419|reactome:R-SCE-9013425|ensemblfungi:YAL029C(gene)|ensemblfungi:YAL029C_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|refseq:NP_009373.1|sgd:S000000027|mint:P32492|dip:DIP-5761N refseq:NP_014678.1|sgd:S000005561|ensemblfungi:YOR035C(gene)|ensemblfungi:YOR035C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017022"(myosin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024660|rcsb pdb:3OPB|dip:DIP-4186N|mint:P51534 psi-mi:"MI:0465"(dip) crc64:E79C0FE72B041E95 crc64:4A0E1C7D41939B44 comment:Deletion of region 545-789 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:jxx/cStiu7zpcGFLmoTedhHVZcY559292 rogid:aahihUKRvHF7B8fqhzg2XIO1tpc559292 rigid:gaZny7uYVZXlpzBzSRFCnllszRQ false glutathione s tranferase tag:n-n|binding-associated region:561-587 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)