#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P17987	uniprotkb:P04062	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	intact:EBI-1564609|uniprotkb:B7Z5G2|uniprotkb:B7Z6S1|uniprotkb:J3KQG4|uniprotkb:J3KQK9|uniprotkb:Q16545|uniprotkb:Q4VX22|uniprotkb:Q6I9R6|uniprotkb:Q9UMJ8|uniprotkb:A8K796|ensembl:ENSP00000314508|ensembl:ENSP00000357357	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:glcm_human(display_long)|uniprotkb:Beta-glucocerebrosidase(gene name synonym)|uniprotkb:Acid beta-glucosidase(gene name synonym)|uniprotkb:D-glucosyl-N-acylsphingosine glucohydrolase(gene name synonym)|uniprotkb:Alglucerase(gene name synonym)|uniprotkb:Imiglucerase(gene name synonym)|uniprotkb:GBA(gene name)|psi-mi:GBA(display_short)|uniprotkb:GC(gene name synonym)|uniprotkb:GLUC(gene name synonym)|uniprotkb:Cholesterol glucosyltransferase(gene name synonym)|uniprotkb:Cholesteryl-beta-glucosidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lu et al. (2010)	pubmed:21098288|doi:10.1073/pnas.1014376107|imex:IM-17146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15893552|imex:IM-17146-1|dip:DIP-188141E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	refseq:NP_001165282.1|refseq:NP_001165283.1|refseq:NP_000148.2|refseq:NP_001005741.1|refseq:NP_001005742.1|dip:DIP-38645N|ensembl:ENSG00000177628(gene)|ensembl:ENST00000327247(transcript)|ensembl:ENST00000368373(transcript)|go:"GO:0004348"(glucosylceramidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006680"(glucosylceramide catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007040"(lysosome organization)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009268"(response to pH)|go:"GO:0014004"(microglia differentiation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019915"(lipid storage)|go:"GO:0021694"(cerebellar Purkinje cell layer formation)|go:"GO:0021859"(pyramidal neuron differentiation)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0023021"(termination of signal transduction)|go:"GO:0030259"(lipid glycosylation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033561"(regulation of water loss via skin)|go:"GO:0033574"(response to testosterone)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0043627"(response to estrogen)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046527"(glucosyltransferase activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050295"(steryl-beta-glucosidase activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061744"(motor behavior)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0072676"(lymphocyte migration)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901805"(beta-glucoside catabolic process)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903061"(positive regulation of protein lipidation)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1905037"(autophagosome organization)|go:"GO:1905165"(regulation of lysosomal protein catabolic process)|interpro:IPR001139(Glycoside hydrolase, family 30)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR033452|interpro:IPR033453|mint:P04062|rcsb pdb:1OGS|rcsb pdb:1Y7V|rcsb pdb:2F61|rcsb pdb:2J25|rcsb pdb:2NSX|rcsb pdb:2NT0|rcsb pdb:2NT1|rcsb pdb:2V3D|rcsb pdb:2V3E|rcsb pdb:2V3F|rcsb pdb:2VT0|rcsb pdb:2WCG|rcsb pdb:2WKL|rcsb pdb:2XWD|rcsb pdb:2XWE|rcsb pdb:3GXD|rcsb pdb:3GXF|rcsb pdb:3GXI|rcsb pdb:3GXM|rcsb pdb:3KE0|rcsb pdb:3KEH|rcsb pdb:3RIK|rcsb pdb:3RIL|rcsb pdb:5LVX|rcsb pdb:6MOZ|rcsb pdb:6Q1N|rcsb pdb:6Q1P|rcsb pdb:6Q6K|rcsb pdb:6Q6L|rcsb pdb:6Q6N|rcsb pdb:6TJJ|rcsb pdb:6TJK|rcsb pdb:6TJQ|rcsb pdb:6TN1|rcsb pdb:6YTP|rcsb pdb:6YTR|rcsb pdb:6YUT|rcsb pdb:6YV3|rcsb pdb:6Z39|rcsb pdb:6Z3I|reactome:R-HSA-1660662|reactome:R-HSA-390471	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	rogid:AWV635bfvuSWV1vflhTcun2riyk9606	rigid:4JpYJnodDopodznaT0iYi3stSKI	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P17987	uniprotkb:P04062	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	intact:EBI-1564609|uniprotkb:B7Z5G2|uniprotkb:B7Z6S1|uniprotkb:J3KQG4|uniprotkb:J3KQK9|uniprotkb:Q16545|uniprotkb:Q4VX22|uniprotkb:Q6I9R6|uniprotkb:Q9UMJ8|uniprotkb:A8K796|ensembl:ENSP00000314508|ensembl:ENSP00000357357	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:glcm_human(display_long)|uniprotkb:Beta-glucocerebrosidase(gene name synonym)|uniprotkb:Acid beta-glucosidase(gene name synonym)|uniprotkb:D-glucosyl-N-acylsphingosine glucohydrolase(gene name synonym)|uniprotkb:Alglucerase(gene name synonym)|uniprotkb:Imiglucerase(gene name synonym)|uniprotkb:GBA(gene name)|psi-mi:GBA(display_short)|uniprotkb:GC(gene name synonym)|uniprotkb:GLUC(gene name synonym)|uniprotkb:Cholesterol glucosyltransferase(gene name synonym)|uniprotkb:Cholesteryl-beta-glucosidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lu et al. (2010)	pubmed:21098288|doi:10.1073/pnas.1014376107|imex:IM-17146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15893569|imex:IM-17146-2|dip:DIP-188141E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	refseq:NP_001165282.1|refseq:NP_001165283.1|refseq:NP_000148.2|refseq:NP_001005741.1|refseq:NP_001005742.1|dip:DIP-38645N|ensembl:ENSG00000177628(gene)|ensembl:ENST00000327247(transcript)|ensembl:ENST00000368373(transcript)|go:"GO:0004348"(glucosylceramidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006680"(glucosylceramide catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007040"(lysosome organization)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009268"(response to pH)|go:"GO:0014004"(microglia differentiation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019915"(lipid storage)|go:"GO:0021694"(cerebellar Purkinje cell layer formation)|go:"GO:0021859"(pyramidal neuron differentiation)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0023021"(termination of signal transduction)|go:"GO:0030259"(lipid glycosylation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033561"(regulation of water loss via skin)|go:"GO:0033574"(response to testosterone)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0043627"(response to estrogen)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046527"(glucosyltransferase activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050295"(steryl-beta-glucosidase activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061744"(motor behavior)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0072676"(lymphocyte migration)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901805"(beta-glucoside catabolic process)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903061"(positive regulation of protein lipidation)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1905037"(autophagosome organization)|go:"GO:1905165"(regulation of lysosomal protein catabolic process)|interpro:IPR001139(Glycoside hydrolase, family 30)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR033452|interpro:IPR033453|mint:P04062|rcsb pdb:1OGS|rcsb pdb:1Y7V|rcsb pdb:2F61|rcsb pdb:2J25|rcsb pdb:2NSX|rcsb pdb:2NT0|rcsb pdb:2NT1|rcsb pdb:2V3D|rcsb pdb:2V3E|rcsb pdb:2V3F|rcsb pdb:2VT0|rcsb pdb:2WCG|rcsb pdb:2WKL|rcsb pdb:2XWD|rcsb pdb:2XWE|rcsb pdb:3GXD|rcsb pdb:3GXF|rcsb pdb:3GXI|rcsb pdb:3GXM|rcsb pdb:3KE0|rcsb pdb:3KEH|rcsb pdb:3RIK|rcsb pdb:3RIL|rcsb pdb:5LVX|rcsb pdb:6MOZ|rcsb pdb:6Q1N|rcsb pdb:6Q1P|rcsb pdb:6Q6K|rcsb pdb:6Q6L|rcsb pdb:6Q6N|rcsb pdb:6TJJ|rcsb pdb:6TJK|rcsb pdb:6TJQ|rcsb pdb:6TN1|rcsb pdb:6YTP|rcsb pdb:6YTR|rcsb pdb:6YUT|rcsb pdb:6YV3|rcsb pdb:6Z39|rcsb pdb:6Z3I|reactome:R-HSA-1660662|reactome:R-HSA-390471	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	rogid:AWV635bfvuSWV1vflhTcun2riyk9606	rigid:4JpYJnodDopodznaT0iYi3stSKI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P22681	uniprotkb:P04062	intact:EBI-518228|uniprotkb:A3KMP8|ensembl:ENSP00000264033	intact:EBI-1564609|uniprotkb:B7Z5G2|uniprotkb:B7Z6S1|uniprotkb:J3KQG4|uniprotkb:J3KQK9|uniprotkb:Q16545|uniprotkb:Q4VX22|uniprotkb:Q6I9R6|uniprotkb:Q9UMJ8|uniprotkb:A8K796|ensembl:ENSP00000314508|ensembl:ENSP00000357357	psi-mi:cbl_human(display_long)|uniprotkb:Signal transduction protein CBL(gene name synonym)|uniprotkb:Proto-oncogene c-Cbl(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)|uniprotkb:RING finger protein 55(gene name synonym)|uniprotkb:CBL(gene name)|psi-mi:CBL(display_short)|uniprotkb:CBL2(gene name synonym)|uniprotkb:RNF55(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)	psi-mi:glcm_human(display_long)|uniprotkb:Beta-glucocerebrosidase(gene name synonym)|uniprotkb:Acid beta-glucosidase(gene name synonym)|uniprotkb:D-glucosyl-N-acylsphingosine glucohydrolase(gene name synonym)|uniprotkb:Alglucerase(gene name synonym)|uniprotkb:Imiglucerase(gene name synonym)|uniprotkb:GBA(gene name)|psi-mi:GBA(display_short)|uniprotkb:GC(gene name synonym)|uniprotkb:GLUC(gene name synonym)|uniprotkb:Cholesterol glucosyltransferase(gene name synonym)|uniprotkb:Cholesteryl-beta-glucosidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lu et al. (2010)	pubmed:21098288|doi:10.1073/pnas.1014376107|imex:IM-17146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15893586|imex:IM-17146-3|dip:DIP-188142E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005179.2|ensembl:ENSP00000264033|dip:DIP-189N|ensembl:ENSG00000110395(gene)|ensembl:ENST00000264033(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008584"(male gonad development)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016600"(flotillin complex)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030426"(growth cone)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0033574"(response to testosterone)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070997"(neuron death)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR009060(UBA-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:P22681|rcsb pdb:1B47|rcsb pdb:1FBV|rcsb pdb:1YVH|rcsb pdb:2CBL|rcsb pdb:2JUJ|rcsb pdb:2K4D|rcsb pdb:2OO9|rcsb pdb:2Y1M|rcsb pdb:2Y1N|rcsb pdb:3BUM|rcsb pdb:3BUN|rcsb pdb:3BUO|rcsb pdb:3BUW|rcsb pdb:3BUX|rcsb pdb:3OB1|rcsb pdb:3OB2|rcsb pdb:3PLF|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4GPL|rcsb pdb:5HKW|rcsb pdb:5HKX|rcsb pdb:5HKY|rcsb pdb:5HKZ|rcsb pdb:5HL0|rcsb pdb:5J3X|rcsb pdb:5O76|rcsb pdb:6O02|rcsb pdb:6O03|rcsb pdb:6XAR|reactome:R-HSA-1059683|reactome:R-HSA-1236382|reactome:R-HSA-1295596|reactome:R-HSA-1433559|reactome:R-HSA-182971|reactome:R-HSA-2173789|reactome:R-HSA-5637810|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-6807004|reactome:R-HSA-8849469|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-912631|reactome:R-HSA-9706369|reactome:R-HSA-9706377	refseq:NP_001165282.1|refseq:NP_001165283.1|refseq:NP_000148.2|refseq:NP_001005741.1|refseq:NP_001005742.1|dip:DIP-38645N|ensembl:ENSG00000177628(gene)|ensembl:ENST00000327247(transcript)|ensembl:ENST00000368373(transcript)|go:"GO:0004348"(glucosylceramidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006680"(glucosylceramide catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007040"(lysosome organization)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009268"(response to pH)|go:"GO:0014004"(microglia differentiation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019915"(lipid storage)|go:"GO:0021694"(cerebellar Purkinje cell layer formation)|go:"GO:0021859"(pyramidal neuron differentiation)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0023021"(termination of signal transduction)|go:"GO:0030259"(lipid glycosylation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033561"(regulation of water loss via skin)|go:"GO:0033574"(response to testosterone)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0043627"(response to estrogen)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046527"(glucosyltransferase activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050295"(steryl-beta-glucosidase activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061744"(motor behavior)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0072676"(lymphocyte migration)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901805"(beta-glucoside catabolic process)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903061"(positive regulation of protein lipidation)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1905037"(autophagosome organization)|go:"GO:1905165"(regulation of lysosomal protein catabolic process)|interpro:IPR001139(Glycoside hydrolase, family 30)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR033452|interpro:IPR033453|mint:P04062|rcsb pdb:1OGS|rcsb pdb:1Y7V|rcsb pdb:2F61|rcsb pdb:2J25|rcsb pdb:2NSX|rcsb pdb:2NT0|rcsb pdb:2NT1|rcsb pdb:2V3D|rcsb pdb:2V3E|rcsb pdb:2V3F|rcsb pdb:2VT0|rcsb pdb:2WCG|rcsb pdb:2WKL|rcsb pdb:2XWD|rcsb pdb:2XWE|rcsb pdb:3GXD|rcsb pdb:3GXF|rcsb pdb:3GXI|rcsb pdb:3GXM|rcsb pdb:3KE0|rcsb pdb:3KEH|rcsb pdb:3RIK|rcsb pdb:3RIL|rcsb pdb:5LVX|rcsb pdb:6MOZ|rcsb pdb:6Q1N|rcsb pdb:6Q1P|rcsb pdb:6Q6K|rcsb pdb:6Q6L|rcsb pdb:6Q6N|rcsb pdb:6TJJ|rcsb pdb:6TJK|rcsb pdb:6TJQ|rcsb pdb:6TN1|rcsb pdb:6YTP|rcsb pdb:6YTR|rcsb pdb:6YUT|rcsb pdb:6YV3|rcsb pdb:6Z39|rcsb pdb:6Z3I|reactome:R-HSA-1660662|reactome:R-HSA-390471	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:WPXFRmBKHEANKUlN/OYsuyAe9a09606	rogid:AWV635bfvuSWV1vflhTcun2riyk9606	rigid:Vnm/gz7wZ4qGprOJ5V1yzpW14lE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)