#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0AFA2	-	intact:EBI-1112775|uniprotkb:P10956|ensemblbacteria:AAC74306|ensemblbacteria:BAA36090	-	psi-mi:narx_ecoli(display_long)|uniprotkb:narX(gene name)|psi-mi:narX(display_short)|uniprotkb:narR(gene name synonym)|uniprotkb:b1222(locus name)|uniprotkb:JW1213(locus name)	-	psi-mi:"MI:0424"(protein kinase assay)	Huynh et al. (2010)	pubmed:21078995|doi:10.1073/pnas.1013081107|imex:IM-17142	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15892796|imex:IM-17142-1|dip:DIP-102557E	-	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0326"(protein)	-	refseq:WP_000918073.1|refseq:NP_415740.1|ensemblbacteria:AAC74306(transcript)|ensemblbacteria:b1222(gene)|ensemblbacteria:BAA36090(gene)|ensemblbacteria:BAA36090(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071249"(cellular response to nitrate)|go:"GO:0071250"(cellular response to nitrite)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR011712(Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region)|interpro:IPR016380(Signal transduction histidine kinase, nitrate/nitrite-sensing)|interpro:IPR029095|interpro:IPR036890|interpro:IPR042295|rcsb pdb:3EZH|rcsb pdb:3EZI|dip:DIP-35785N	-	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:BAnbo/MQUxz6asds5M06MKwhYtc83333	-	-	false	mutation decreasing interaction rate:404-404|mutation disrupting interaction rate:400-400|mutation decreasing interaction rate:404-404|mutation disrupting interaction rate:400-400|mutation decreasing interaction rate:404-404	-	-	-	psi-mi:"MI:0396"(predetermined participant)	-
uniprotkb:P0AF28	uniprotkb:P0AFA2	intact:EBI-1122899|uniprotkb:P10957|ensemblbacteria:BAA36089|ensemblbacteria:AAC74305	intact:EBI-1112775|uniprotkb:P10956|ensemblbacteria:AAC74306|ensemblbacteria:BAA36090	psi-mi:narl_ecoli(display_long)|uniprotkb:narL(gene name)|psi-mi:narL(display_short)|uniprotkb:frdR(gene name synonym)|uniprotkb:b1221(locus name)|uniprotkb:JW1212(locus name)	psi-mi:narx_ecoli(display_long)|uniprotkb:narX(gene name)|psi-mi:narX(display_short)|uniprotkb:narR(gene name synonym)|uniprotkb:b1222(locus name)|uniprotkb:JW1213(locus name)	psi-mi:"MI:0841"(phosphotransferase assay)	Huynh et al. (2010)	pubmed:21078995|doi:10.1073/pnas.1013081107|imex:IM-17142	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0844"(phosphotransfer reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15892822|imex:IM-17142-2|dip:DIP-188130E	-	-	psi-mi:"MI:0843"(phosphate acceptor)	psi-mi:"MI:0842"(phosphate donor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415739.1|refseq:WP_000070491.1|ensemblbacteria:AAC74305(transcript)|ensemblbacteria:b1221(gene)|ensemblbacteria:BAA36089(gene)|ensemblbacteria:BAA36089(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042802"(identical protein binding)|go:"GO:0090352"(regulation of nitrate assimilation)|interpro:IPR000792(Bacterial regulatory protein, LuxR)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR036388|rcsb pdb:1A04|rcsb pdb:1JE8|rcsb pdb:1RNL|rcsb pdb:1ZG1|rcsb pdb:1ZG5|dip:DIP-35941N	refseq:WP_000918073.1|refseq:NP_415740.1|ensemblbacteria:AAC74306(transcript)|ensemblbacteria:b1222(gene)|ensemblbacteria:BAA36090(gene)|ensemblbacteria:BAA36090(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071249"(cellular response to nitrate)|go:"GO:0071250"(cellular response to nitrite)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR011712(Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region)|interpro:IPR016380(Signal transduction histidine kinase, nitrate/nitrite-sensing)|interpro:IPR029095|interpro:IPR036890|interpro:IPR042295|rcsb pdb:3EZH|rcsb pdb:3EZI|dip:DIP-35785N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:mOHdNslRmG2RuK4q2SiPAE87j6483333	rogid:BAnbo/MQUxz6asds5M06MKwhYtc83333	rigid:U33EACDD620vgK7zQVTRZn9jld0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AF28	uniprotkb:P0AFA2	intact:EBI-1122899|uniprotkb:P10957|ensemblbacteria:BAA36089|ensemblbacteria:AAC74305	intact:EBI-1112775|uniprotkb:P10956|ensemblbacteria:AAC74306|ensemblbacteria:BAA36090	psi-mi:narl_ecoli(display_long)|uniprotkb:narL(gene name)|psi-mi:narL(display_short)|uniprotkb:frdR(gene name synonym)|uniprotkb:b1221(locus name)|uniprotkb:JW1212(locus name)	psi-mi:narx_ecoli(display_long)|uniprotkb:narX(gene name)|psi-mi:narX(display_short)|uniprotkb:narR(gene name synonym)|uniprotkb:b1222(locus name)|uniprotkb:JW1213(locus name)	psi-mi:"MI:1019"(protein phosphatase assay)	Huynh et al. (2010)	pubmed:21078995|doi:10.1073/pnas.1013081107|imex:IM-17142	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15892839|imex:IM-17142-3|dip:DIP-188130E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415739.1|refseq:WP_000070491.1|ensemblbacteria:AAC74305(transcript)|ensemblbacteria:b1221(gene)|ensemblbacteria:BAA36089(gene)|ensemblbacteria:BAA36089(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042802"(identical protein binding)|go:"GO:0090352"(regulation of nitrate assimilation)|interpro:IPR000792(Bacterial regulatory protein, LuxR)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR036388|rcsb pdb:1A04|rcsb pdb:1JE8|rcsb pdb:1RNL|rcsb pdb:1ZG1|rcsb pdb:1ZG5|dip:DIP-35941N	refseq:WP_000918073.1|refseq:NP_415740.1|ensemblbacteria:AAC74306(transcript)|ensemblbacteria:b1222(gene)|ensemblbacteria:BAA36090(gene)|ensemblbacteria:BAA36090(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071249"(cellular response to nitrate)|go:"GO:0071250"(cellular response to nitrite)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR011712(Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region)|interpro:IPR016380(Signal transduction histidine kinase, nitrate/nitrite-sensing)|interpro:IPR029095|interpro:IPR036890|interpro:IPR042295|rcsb pdb:3EZH|rcsb pdb:3EZI|dip:DIP-35785N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:mOHdNslRmG2RuK4q2SiPAE87j6483333	rogid:BAnbo/MQUxz6asds5M06MKwhYtc83333	rigid:U33EACDD620vgK7zQVTRZn9jld0	false	-	mutation disrupting interaction rate:404-404|mutation decreasing interaction rate:404-404|mutation disrupting interaction rate:400-400|mutation disrupting interaction:404-404,399-399|mutation decreasing interaction:399-399|mutation decreasing interaction:400-400,399-399|mutation disrupting interaction:404-404,399-399|mutation decreasing interaction rate:404-404|mutation disrupting interaction rate:400-400|mutation disrupting interaction rate:404-404	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)