#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BUR4 uniprotkb:Q9BUR4 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15892139|imex:IM-15887-1|dip:DIP-186236E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rigid:N455HWCDWkTIZmmvAL8bLfO07Cc false enhanced green fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38432 uniprotkb:Q9BUR4 intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym) psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15892232|imex:IM-15887-6|dip:DIP-186238E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432 refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rigid:MD4nHTwI1WP9qfuySi8bqSvtsps false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BUR4 uniprotkb:Q9BUR4 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15892211|imex:IM-15887-5|dip:DIP-186236E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rigid:N455HWCDWkTIZmmvAL8bLfO07Cc false enhanced green fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16637 uniprotkb:P38432 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15892194|imex:IM-15887-4|dip:DIP-186240E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606 rigid:F8IXw3UntEnXDwHpA8+51/mn0YM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UHI6 uniprotkb:Q9BUR4 intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym) psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15892177|imex:IM-15887-3|dip:DIP-186242E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process) refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rigid:VJC8J3C9W9wKB1HK8R2sqAChCoY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38432 uniprotkb:Q9BUR4 intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym) psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15892160|imex:IM-15887-2|dip:DIP-186238E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432 refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rigid:MD4nHTwI1WP9qfuySi8bqSvtsps false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14974-1 uniprotkb:Q9BUR4 intact:EBI-15488647|ensembl:ENSP00000290158|ensembl:ENSP00000464042 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 psi-mi:q14974-1(display_long)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym) psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15892338|imex:IM-15887-12|dip:DIP-186241E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-286758(isoform-parent)|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript) refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rigid:8LW4UQKZqmihzSt58ndp6ucHFVg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14974-1 uniprotkb:Q16637 intact:EBI-15488647|ensembl:ENSP00000290158|ensembl:ENSP00000464042 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:q14974-1(display_long)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15892338|imex:IM-15887-12|dip:DIP-186241E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-286758(isoform-parent)|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rigid:8LW4UQKZqmihzSt58ndp6ucHFVg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BUR4 uniprotkb:Q9BUR4 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15892319|imex:IM-15887-11|dip:DIP-186236E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rigid:N455HWCDWkTIZmmvAL8bLfO07Cc false enhanced green fluorescent protein tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16637 uniprotkb:P38432 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15892302|imex:IM-15887-10|dip:DIP-186240E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606 rigid:F8IXw3UntEnXDwHpA8+51/mn0YM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q16637 uniprotkb:Q9BUR4 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15892285|imex:IM-15887-9|dip:DIP-186239E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rigid:4dXmU9BvdHk7hwizyuz9n2bGiVQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q16637 uniprotkb:P14678 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-372458|uniprotkb:Q15490|uniprotkb:Q9UIS5|uniprotkb:Q6IB35|ensembl:ENSP00000412566 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:rsmb_human(display_long)|uniprotkb:Sm protein B/B'(gene name synonym)|uniprotkb:SNRPB(gene name)|psi-mi:SNRPB(display_short)|uniprotkb:COD(gene name synonym)|uniprotkb:SNRPB1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15892266|imex:IM-15887-8|dip:DIP-186243E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_003082.1|refseq:NP_937859.1|ensembl:ENSG00000125835(gene)|ensembl:ENST00000438552(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007420"(brain development)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:1990446"(U1 snRNP binding)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017131(Small ribonucleoprotein associated, SmB/SmN)|mint:P14678|rcsb pdb:1D3B|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4PJO|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|dip:DIP-31239N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:zm9vJCpHG8w5iKErbOphUDCXTPk9606 rigid:j8KlwNafaJz5UWzQ6VsBnYTC6oA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q16637 uniprotkb:Q9UHI6 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15892266|imex:IM-15887-8|dip:DIP-186243E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606 rigid:j8KlwNafaJz5UWzQ6VsBnYTC6oA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q16637 uniprotkb:P38432 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15892266|imex:IM-15887-8|dip:DIP-186243E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606 rigid:j8KlwNafaJz5UWzQ6VsBnYTC6oA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q16637 uniprotkb:Q9BUR4 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15892356|imex:IM-15887-13|dip:DIP-186239E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rigid:4dXmU9BvdHk7hwizyuz9n2bGiVQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14974-1 uniprotkb:Q16637 intact:EBI-15488647|ensembl:ENSP00000290158|ensembl:ENSP00000464042 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:q14974-1(display_long)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15892249|imex:IM-15887-7|dip:DIP-60831E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-286758(isoform-parent)|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rigid:GlihA+uA1ZTBZL1ZxStYvMQyKek false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BUR4 uniprotkb:Q14974-1 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 intact:EBI-15488647|ensembl:ENSP00000290158|ensembl:ENSP00000464042 psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:q14974-1(display_long)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15892391|imex:IM-15887-15|dip:DIP-186241E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N intact:EBI-286758(isoform-parent)|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606 rigid:8LW4UQKZqmihzSt58ndp6ucHFVg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BUR4 uniprotkb:Q16637 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15892391|imex:IM-15887-15|dip:DIP-186241E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rigid:8LW4UQKZqmihzSt58ndp6ucHFVg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BUR4 uniprotkb:Q16637 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15892373|imex:IM-15887-14|dip:DIP-186237E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rigid:mWReNz7lOWXEaT2Dy8t00ejzmYE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BUR4 uniprotkb:P38432 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316 psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15892373|imex:IM-15887-14|dip:DIP-186237E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606 rigid:mWReNz7lOWXEaT2Dy8t00ejzmYE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BUR4 uniprotkb:Q16637 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15892409|imex:IM-15887-16|dip:DIP-186237E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rigid:mWReNz7lOWXEaT2Dy8t00ejzmYE false enhanced green fluorescent protein tag:n-n|sufficient binding region:150-548|sufficient binding region:1-533 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BUR4 uniprotkb:P38432 intact:EBI-2563542|uniprotkb:Q9NW09|uniprotkb:Q08ET9|uniprotkb:B3KPR9|uniprotkb:D3DTQ4|ensembl:ENSP00000324203|ensembl:ENSP00000379727|ensembl:ENSP00000397219|ensembl:ENSP00000411061 intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316 psi-mi:tcab1_human(display_long)|uniprotkb:TCAB1(gene name synonym)|uniprotkb:WDR79(gene name synonym)|uniprotkb:WD repeat-containing protein 79(gene name synonym)|uniprotkb:WRAP53(gene name)|psi-mi:WRAP53(display_short)|uniprotkb:WD40 repeat-containing protein antisense to TP53 gene(gene name synonym) psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mahmoudi et al. (2010) pubmed:21072240|doi:10.1371/journal.pbio.1000521|imex:IM-15887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15892409|imex:IM-15887-16|dip:DIP-186237E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137462.1|refseq:NP_001137463.1|refseq:NP_001137464.1|refseq:NP_060551.2|ensembl:ENSG00000141499(gene)|ensembl:ENST00000316024(transcript)|ensembl:ENST00000396463(transcript)|ensembl:ENST00000431639(transcript)|ensembl:ENST00000457584(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032203"(telomere formation via telomerase)|go:"GO:0034337"(RNA folding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051087"(chaperone binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090671"(telomerase RNA localization to Cajal body)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904867"(protein localization to Cajal body)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-390471|dip:DIP-56796N refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:/tnht4JqijEJpOj3elodNqbYeWg9606 rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606 rigid:mWReNz7lOWXEaT2Dy8t00ejzmYE false enhanced green fluorescent protein tag:n-n|sufficient binding region:150-548|sufficient binding region:1-533 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)