#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75689 uniprotkb:Q9H1H9 intact:EBI-714732|uniprotkb:F6XZ68|uniprotkb:B3KRZ4|uniprotkb:B4DVA6|uniprotkb:A4D2Q2|uniprotkb:H7C2Q4|ensembl:ENSP00000265846 intact:EBI-1759129|uniprotkb:Q5THQ2|uniprotkb:Q5THQ3|uniprotkb:Q9H193|uniprotkb:Q9H194|uniprotkb:Q9H1H8|uniprotkb:A0JP21|uniprotkb:A0JP22|uniprotkb:F2Z382|ensembl:ENSP00000259711 psi-mi:adap1_human(display_long)|uniprotkb:Putative MAPK-activating protein PM25(gene name synonym)|uniprotkb:ADAP1(gene name)|psi-mi:ADAP1(display_short)|uniprotkb:CENTA1(gene name synonym)|uniprotkb:Centaurin-alpha-1(gene name synonym) psi-mi:ki13a_human(display_long)|uniprotkb:KIF13A(gene name)|psi-mi:KIF13A(display_short)|uniprotkb:RBKIN(gene name synonym)|uniprotkb:Kinesin-like protein RBKIN(gene name synonym) psi-mi:"MI:0096"(pull down) Tong et al. (2010) pubmed:21057110|doi:10.1073/pnas.1009008107|imex:IM-17134 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15890424|imex:IM-17134-2|dip:DIP-188118E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271237.1|refseq:NP_001271238.1|refseq:NP_001271239.1|refseq:NP_001271240.1|refseq:NP_006860.1|ensembl:ENSG00000105963(gene)|ensembl:ENST00000265846(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037278|interpro:IPR037849|interpro:IPR037851|interpro:IPR038508|rcsb pdb:3FEH|rcsb pdb:3FM8|rcsb pdb:3LJU|rcsb pdb:3MDB|reactome:R-HSA-1251985|dip:DIP-41731N refseq:NP_001099036.1|refseq:NP_001099037.1|refseq:NP_001099038.1|refseq:NP_071396.4|refseq:NP_001230352.1|dip:DIP-52276N|ensembl:ENSG00000137177(gene)|ensembl:ENST00000259711(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030496"(midbody)|go:"GO:0032438"(melanosome organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0051301"(cell division)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:1990939"|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR032923|interpro:IPR036961|reactome:R-HSA-390471|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:YmpvHy8TiJhpy1iPCknJk2Teqxg9606 rogid:zid/j0x9eaaxmX+IhSseYrrN++09606 rigid:zYXA1lGqDEuKjxPKBEOPsWdoeTs false - binding-associated region:1-556|glutathione s tranferase tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9NQT8 uniprotkb:O75689 intact:EBI-766408|uniprotkb:O75134|uniprotkb:Q9BYJ6|intact:EBI-11144050|uniprotkb:F8VPJ2|uniprotkb:B4DGY5|uniprotkb:B5MC45|ensembl:ENSP00000427900 intact:EBI-714732|uniprotkb:F6XZ68|uniprotkb:B3KRZ4|uniprotkb:B4DVA6|uniprotkb:A4D2Q2|uniprotkb:H7C2Q4|ensembl:ENSP00000265846 psi-mi:ki13b_human(display_long)|uniprotkb:Kinesin-like protein GAKIN(gene name synonym)|uniprotkb:KIF13B(gene name)|psi-mi:KIF13B(display_short)|uniprotkb:GAKIN(gene name synonym)|uniprotkb:KIAA0639(gene name synonym) psi-mi:adap1_human(display_long)|uniprotkb:Putative MAPK-activating protein PM25(gene name synonym)|uniprotkb:ADAP1(gene name)|psi-mi:ADAP1(display_short)|uniprotkb:CENTA1(gene name synonym)|uniprotkb:Centaurin-alpha-1(gene name synonym) psi-mi:"MI:0096"(pull down) Tong et al. (2010) pubmed:21057110|doi:10.1073/pnas.1009008107|imex:IM-17134 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15890403|imex:IM-17134-1|dip:DIP-188119E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056069.2|dip:DIP-34586N|ensembl:ENSG00000197892(gene)|ensembl:ENST00000524189(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005902"(microvillus)|go:"GO:0006605"(protein targeting)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0033270"(paranode region of axon)|go:"GO:0042110"(T cell activation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990939"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR032405|interpro:IPR036859|interpro:IPR036961|rcsb pdb:2COW|rcsb pdb:3FM8|rcsb pdb:3GBJ|rcsb pdb:3MDB|reactome:R-HSA-6811434|reactome:R-HSA-983189 refseq:NP_001271237.1|refseq:NP_001271238.1|refseq:NP_001271239.1|refseq:NP_001271240.1|refseq:NP_006860.1|ensembl:ENSG00000105963(gene)|ensembl:ENST00000265846(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037278|interpro:IPR037849|interpro:IPR037851|interpro:IPR038508|rcsb pdb:3FEH|rcsb pdb:3FM8|rcsb pdb:3LJU|rcsb pdb:3MDB|reactome:R-HSA-1251985|dip:DIP-41731N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:dasf1WDho4yX7DWVOYfIpVNcRlE9606 rogid:YmpvHy8TiJhpy1iPCknJk2Teqxg9606 rigid:Cbayo0aIc3xfjReE91ESPY8fXNE false binding-associated region:440-545 glutathione s tranferase tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9NQT8 uniprotkb:O75689 intact:EBI-766408|uniprotkb:O75134|uniprotkb:Q9BYJ6|intact:EBI-11144050|uniprotkb:F8VPJ2|uniprotkb:B4DGY5|uniprotkb:B5MC45|ensembl:ENSP00000427900 intact:EBI-714732|uniprotkb:F6XZ68|uniprotkb:B3KRZ4|uniprotkb:B4DVA6|uniprotkb:A4D2Q2|uniprotkb:H7C2Q4|ensembl:ENSP00000265846 psi-mi:ki13b_human(display_long)|uniprotkb:Kinesin-like protein GAKIN(gene name synonym)|uniprotkb:KIF13B(gene name)|psi-mi:KIF13B(display_short)|uniprotkb:GAKIN(gene name synonym)|uniprotkb:KIAA0639(gene name synonym) psi-mi:adap1_human(display_long)|uniprotkb:Putative MAPK-activating protein PM25(gene name synonym)|uniprotkb:ADAP1(gene name)|psi-mi:ADAP1(display_short)|uniprotkb:CENTA1(gene name synonym)|uniprotkb:Centaurin-alpha-1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Tong et al. (2010) pubmed:21057110|doi:10.1073/pnas.1009008107|imex:IM-17134 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15890447|imex:IM-17134-3|dip:DIP-188119E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056069.2|dip:DIP-34586N|ensembl:ENSG00000197892(gene)|ensembl:ENST00000524189(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005902"(microvillus)|go:"GO:0006605"(protein targeting)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0033270"(paranode region of axon)|go:"GO:0042110"(T cell activation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990939"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR032405|interpro:IPR036859|interpro:IPR036961|rcsb pdb:2COW|rcsb pdb:3FM8|rcsb pdb:3GBJ|rcsb pdb:3MDB|reactome:R-HSA-6811434|reactome:R-HSA-983189 refseq:NP_001271237.1|refseq:NP_001271238.1|refseq:NP_001271239.1|refseq:NP_001271240.1|refseq:NP_006860.1|ensembl:ENSG00000105963(gene)|ensembl:ENST00000265846(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037278|interpro:IPR037849|interpro:IPR037851|interpro:IPR038508|rcsb pdb:3FEH|rcsb pdb:3FM8|rcsb pdb:3LJU|rcsb pdb:3MDB|reactome:R-HSA-1251985|dip:DIP-41731N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:dasf1WDho4yX7DWVOYfIpVNcRlE9606 rogid:YmpvHy8TiJhpy1iPCknJk2Teqxg9606 rigid:Cbayo0aIc3xfjReE91ESPY8fXNE false binding-associated region:440-545 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NQT8 uniprotkb:O75689 intact:EBI-766408|uniprotkb:O75134|uniprotkb:Q9BYJ6|intact:EBI-11144050|uniprotkb:F8VPJ2|uniprotkb:B4DGY5|uniprotkb:B5MC45|ensembl:ENSP00000427900 intact:EBI-714732|uniprotkb:F6XZ68|uniprotkb:B3KRZ4|uniprotkb:B4DVA6|uniprotkb:A4D2Q2|uniprotkb:H7C2Q4|ensembl:ENSP00000265846 psi-mi:ki13b_human(display_long)|uniprotkb:Kinesin-like protein GAKIN(gene name synonym)|uniprotkb:KIF13B(gene name)|psi-mi:KIF13B(display_short)|uniprotkb:GAKIN(gene name synonym)|uniprotkb:KIAA0639(gene name synonym) psi-mi:adap1_human(display_long)|uniprotkb:Putative MAPK-activating protein PM25(gene name synonym)|uniprotkb:ADAP1(gene name)|psi-mi:ADAP1(display_short)|uniprotkb:CENTA1(gene name synonym)|uniprotkb:Centaurin-alpha-1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Tong et al. (2010) pubmed:21057110|doi:10.1073/pnas.1009008107|imex:IM-17134 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15890466|imex:IM-17134-4|dip:DIP-188119E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056069.2|dip:DIP-34586N|ensembl:ENSG00000197892(gene)|ensembl:ENST00000524189(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005902"(microvillus)|go:"GO:0006605"(protein targeting)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0033270"(paranode region of axon)|go:"GO:0042110"(T cell activation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990939"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR032405|interpro:IPR036859|interpro:IPR036961|rcsb pdb:2COW|rcsb pdb:3FM8|rcsb pdb:3GBJ|rcsb pdb:3MDB|reactome:R-HSA-6811434|reactome:R-HSA-983189 refseq:NP_001271237.1|refseq:NP_001271238.1|refseq:NP_001271239.1|refseq:NP_001271240.1|refseq:NP_006860.1|ensembl:ENSG00000105963(gene)|ensembl:ENST00000265846(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037278|interpro:IPR037849|interpro:IPR037851|interpro:IPR038508|rcsb pdb:3FEH|rcsb pdb:3FM8|rcsb pdb:3LJU|rcsb pdb:3MDB|reactome:R-HSA-1251985|dip:DIP-41731N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:dasf1WDho4yX7DWVOYfIpVNcRlE9606 rogid:YmpvHy8TiJhpy1iPCknJk2Teqxg9606 rigid:Cbayo0aIc3xfjReE91ESPY8fXNE false sufficient binding region:440-545 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NQT8 uniprotkb:O75689 intact:EBI-766408|uniprotkb:O75134|uniprotkb:Q9BYJ6|intact:EBI-11144050|uniprotkb:F8VPJ2|uniprotkb:B4DGY5|uniprotkb:B5MC45|ensembl:ENSP00000427900 intact:EBI-714732|uniprotkb:F6XZ68|uniprotkb:B3KRZ4|uniprotkb:B4DVA6|uniprotkb:A4D2Q2|uniprotkb:H7C2Q4|ensembl:ENSP00000265846 psi-mi:ki13b_human(display_long)|uniprotkb:Kinesin-like protein GAKIN(gene name synonym)|uniprotkb:KIF13B(gene name)|psi-mi:KIF13B(display_short)|uniprotkb:GAKIN(gene name synonym)|uniprotkb:KIAA0639(gene name synonym) psi-mi:adap1_human(display_long)|uniprotkb:Putative MAPK-activating protein PM25(gene name synonym)|uniprotkb:ADAP1(gene name)|psi-mi:ADAP1(display_short)|uniprotkb:CENTA1(gene name synonym)|uniprotkb:Centaurin-alpha-1(gene name synonym) psi-mi:"MI:0096"(pull down) Tong et al. (2010) pubmed:21057110|doi:10.1073/pnas.1009008107|imex:IM-17134 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15890504|imex:IM-17134-6|dip:DIP-188119E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056069.2|dip:DIP-34586N|ensembl:ENSG00000197892(gene)|ensembl:ENST00000524189(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005902"(microvillus)|go:"GO:0006605"(protein targeting)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0033270"(paranode region of axon)|go:"GO:0042110"(T cell activation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990939"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR032405|interpro:IPR036859|interpro:IPR036961|rcsb pdb:2COW|rcsb pdb:3FM8|rcsb pdb:3GBJ|rcsb pdb:3MDB|reactome:R-HSA-6811434|reactome:R-HSA-983189 refseq:NP_001271237.1|refseq:NP_001271238.1|refseq:NP_001271239.1|refseq:NP_001271240.1|refseq:NP_006860.1|ensembl:ENSG00000105963(gene)|ensembl:ENST00000265846(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037278|interpro:IPR037849|interpro:IPR037851|interpro:IPR038508|rcsb pdb:3FEH|rcsb pdb:3FM8|rcsb pdb:3LJU|rcsb pdb:3MDB|reactome:R-HSA-1251985|dip:DIP-41731N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:dasf1WDho4yX7DWVOYfIpVNcRlE9606 rogid:YmpvHy8TiJhpy1iPCknJk2Teqxg9606 rigid:Cbayo0aIc3xfjReE91ESPY8fXNE false binding-associated region:1-550|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9NQT8 uniprotkb:O75689 intact:EBI-766408|uniprotkb:O75134|uniprotkb:Q9BYJ6|intact:EBI-11144050|uniprotkb:F8VPJ2|uniprotkb:B4DGY5|uniprotkb:B5MC45|ensembl:ENSP00000427900 intact:EBI-714732|uniprotkb:F6XZ68|uniprotkb:B3KRZ4|uniprotkb:B4DVA6|uniprotkb:A4D2Q2|uniprotkb:H7C2Q4|ensembl:ENSP00000265846 psi-mi:ki13b_human(display_long)|uniprotkb:Kinesin-like protein GAKIN(gene name synonym)|uniprotkb:KIF13B(gene name)|psi-mi:KIF13B(display_short)|uniprotkb:GAKIN(gene name synonym)|uniprotkb:KIAA0639(gene name synonym) psi-mi:adap1_human(display_long)|uniprotkb:Putative MAPK-activating protein PM25(gene name synonym)|uniprotkb:ADAP1(gene name)|psi-mi:ADAP1(display_short)|uniprotkb:CENTA1(gene name synonym)|uniprotkb:Centaurin-alpha-1(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Tong et al. (2010) pubmed:21057110|doi:10.1073/pnas.1009008107|imex:IM-17134 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15890485|imex:IM-17134-5|dip:DIP-188119E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056069.2|dip:DIP-34586N|ensembl:ENSG00000197892(gene)|ensembl:ENST00000524189(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005902"(microvillus)|go:"GO:0006605"(protein targeting)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0033270"(paranode region of axon)|go:"GO:0042110"(T cell activation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990939"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR032405|interpro:IPR036859|interpro:IPR036961|rcsb pdb:2COW|rcsb pdb:3FM8|rcsb pdb:3GBJ|rcsb pdb:3MDB|reactome:R-HSA-6811434|reactome:R-HSA-983189 refseq:NP_001271237.1|refseq:NP_001271238.1|refseq:NP_001271239.1|refseq:NP_001271240.1|refseq:NP_006860.1|ensembl:ENSG00000105963(gene)|ensembl:ENST00000265846(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037278|interpro:IPR037849|interpro:IPR037851|interpro:IPR038508|rcsb pdb:3FEH|rcsb pdb:3FM8|rcsb pdb:3LJU|rcsb pdb:3MDB|reactome:R-HSA-1251985|dip:DIP-41731N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:dasf1WDho4yX7DWVOYfIpVNcRlE9606 rogid:YmpvHy8TiJhpy1iPCknJk2Teqxg9606 rigid:Cbayo0aIc3xfjReE91ESPY8fXNE false binding-associated region:440-545 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NQT8 uniprotkb:O75689 intact:EBI-766408|uniprotkb:O75134|uniprotkb:Q9BYJ6|intact:EBI-11144050|uniprotkb:F8VPJ2|uniprotkb:B4DGY5|uniprotkb:B5MC45|ensembl:ENSP00000427900 intact:EBI-714732|uniprotkb:F6XZ68|uniprotkb:B3KRZ4|uniprotkb:B4DVA6|uniprotkb:A4D2Q2|uniprotkb:H7C2Q4|ensembl:ENSP00000265846 psi-mi:ki13b_human(display_long)|uniprotkb:Kinesin-like protein GAKIN(gene name synonym)|uniprotkb:KIF13B(gene name)|psi-mi:KIF13B(display_short)|uniprotkb:GAKIN(gene name synonym)|uniprotkb:KIAA0639(gene name synonym) psi-mi:adap1_human(display_long)|uniprotkb:Putative MAPK-activating protein PM25(gene name synonym)|uniprotkb:ADAP1(gene name)|psi-mi:ADAP1(display_short)|uniprotkb:CENTA1(gene name synonym)|uniprotkb:Centaurin-alpha-1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Tong et al. (2010) pubmed:21057110|doi:10.1073/pnas.1009008107|imex:IM-17134 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15890525|imex:IM-17134-7|dip:DIP-188119E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056069.2|dip:DIP-34586N|ensembl:ENSG00000197892(gene)|ensembl:ENST00000524189(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005902"(microvillus)|go:"GO:0006605"(protein targeting)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0033270"(paranode region of axon)|go:"GO:0042110"(T cell activation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990939"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR032405|interpro:IPR036859|interpro:IPR036961|rcsb pdb:2COW|rcsb pdb:3FM8|rcsb pdb:3GBJ|rcsb pdb:3MDB|reactome:R-HSA-6811434|reactome:R-HSA-983189 refseq:NP_001271237.1|refseq:NP_001271238.1|refseq:NP_001271239.1|refseq:NP_001271240.1|refseq:NP_006860.1|ensembl:ENSG00000105963(gene)|ensembl:ENST00000265846(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037278|interpro:IPR037849|interpro:IPR037851|interpro:IPR038508|rcsb pdb:3FEH|rcsb pdb:3FM8|rcsb pdb:3LJU|rcsb pdb:3MDB|reactome:R-HSA-1251985|dip:DIP-41731N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:dasf1WDho4yX7DWVOYfIpVNcRlE9606 rogid:YmpvHy8TiJhpy1iPCknJk2Teqxg9606 rigid:Cbayo0aIc3xfjReE91ESPY8fXNE false binding-associated region:440-545 mutation disrupting interaction strength:211-211|mutation disrupting interaction strength:211-211 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)