#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P61925	uniprotkb:P62826	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15886863|imex:IM-16072-3|dip:DIP-186940E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N	refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606	rigid:9dVVB35QqhdBNzr7BfoNtlz2E3c	false	binding-associated region:35-47|fluorescein-5-maleimide label:c-c	binding-associated region:1-180	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:Q6P5F9	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15886863|imex:IM-16072-3|dip:DIP-186940E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N	rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090	rigid:9dVVB35QqhdBNzr7BfoNtlz2E3c	false	binding-associated region:35-47|fluorescein-5-maleimide label:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04618	uniprotkb:Q6P5F9	intact:EBI-6164309	intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178	psi-mi:rev_hv1h2(display_long)|uniprotkb:rev(gene name)|psi-mi:rev(display_short)|uniprotkb:ART/TRS(gene name synonym)|uniprotkb:Anti-repression transactivator(gene name synonym)|uniprotkb:Regulator of expression of viral proteins(gene name synonym)	psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15886844|imex:IM-16072-2|dip:DIP-186943E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000625(Anti-repression trans-activator protein, REV protein)|rcsb pdb:6HIP|rcsb pdb:7JYA|go:"GO:0051028"(mRNA transport)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0016032"(viral process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0044196"(host cell nucleolus)|refseq:NP_057854.1|dip:DIP-61717N|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-164843|reactome:R-HSA-165054|reactome:R-HSA-173107|reactome:R-HSA-175474|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180746|reactome:R-HSA-180910	rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/11/01	rogid:R+Ji+DXMeV/BnOTb7qMiCVxEKRU11706	rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090	rigid:84M2CzJK/FYVN+ImdQk/sVCu08k	false	binding-associated region:72-83	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:Q6P5F9	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15886822|imex:IM-16072-1|dip:DIP-186939E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N	rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090	rigid:aR8dO5dRCD+J13l6HU4WfCo4T34	false	binding-associated region:35-47|mutation increasing interaction:35-35	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-15886963	uniprotkb:Q6P5F9	dip:DIP-59068N	intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178	psi-mi:s1nes(display_short)|psi-mi:EBI-15886963(display_long)	psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15886966|imex:IM-16072-7|dip:DIP-186944E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:7nqs9quFy0F3vTVkHrpr2E3EwHI-2	rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090	rigid:YNWG9h8z+TqZr0cNPVTOpAmsOHs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q83414	uniprotkb:Q6P5F9	intact:EBI-15886983	intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178	psi-mi:q83414_mumiv(display_long)	psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:10794(mvm)|taxid:10794(Murine minute virus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15886988|imex:IM-16072-8|dip:DIP-186945E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59069N	rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:ug1FZVT/CTRk6OLpiazSX0THegQ10794	rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090	rigid:Oi23fUMHz/lDasAU8FiDqu/N9YU	false	binding-associated region:78-91	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95149	uniprotkb:Q6P5F9	intact:EBI-714033|uniprotkb:D3DW76|ensembl:ENSP00000309831|ensembl:ENSP00000454852|ensembl:ENSP00000456224|ensembl:ENSP00000458053|uniprotkb:A6NE34|uniprotkb:A8K0B0	intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178	psi-mi:spn1_human(display_long)|uniprotkb:RNA U transporter 1(gene name synonym)|uniprotkb:SNUPN(gene name)|psi-mi:SNUPN(display_short)|uniprotkb:RNUT1(gene name synonym)|uniprotkb:SPN1(gene name synonym)	psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15887007|imex:IM-16072-9|dip:DIP-186942E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169371(gene)|ensembl:ENST00000308588(transcript)|ensembl:ENST00000564644(transcript)|ensembl:ENST00000564675(transcript)|ensembl:ENST00000567134(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR017336(Snurportin-1)|interpro:IPR024721|rcsb pdb:1XK5|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3GB8|rcsb pdb:3GJX|rcsb pdb:3LWW|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:5DIS|reactome:R-HSA-191859|refseq:NP_001036046.1|refseq:NP_001036053.1|refseq:NP_005692.1|dip:DIP-48513N	rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:MZ8KWSQHNhfWfYl8tKKIJrFMKLw9606	rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090	rigid:tDORbBz1Rds87X6dQc9IXWubrCg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:P62826	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name)	psi-mi:"MI:0071"(molecular sieving)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15886941|imex:IM-16072-6|dip:DIP-186940E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N	refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606	rigid:9dVVB35QqhdBNzr7BfoNtlz2E3c	false	binding-associated region:35-47	binding-associated region:1-180	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P61925	uniprotkb:Q6P5F9	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15886941|imex:IM-16072-6|dip:DIP-186940E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N	rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090	rigid:9dVVB35QqhdBNzr7BfoNtlz2E3c	false	binding-associated region:35-47	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P61925	uniprotkb:Q6P5F9	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15886922|imex:IM-16072-5|dip:DIP-186939E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N	rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090	rigid:aR8dO5dRCD+J13l6HU4WfCo4T34	false	binding-associated region:30-54	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P24346	uniprotkb:Q6P5F9	intact:EBI-15886887	intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178	psi-mi:ddx3_xenla(display_long)|uniprotkb:an3(gene name)|psi-mi:an3(display_short)	psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15886903|imex:IM-16072-4|dip:DIP-186946E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030027"(lamellipodium)|go:"GO:0031252"(cell leading edge)|go:"GO:0061702"(inflammasome complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|refseq:NP_001095245.1|dip:DIP-59067N	rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:aRP2kbxdVo6hSlewg2De9CP/eCM8355	rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090	rigid:9I3aeJlJwuLNaEU7Djs/VKVhi94	false	binding-associated region:8-21	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62826	uniprotkb:Q6P5F9	intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215	intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178	psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name)	psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Güttler et al. (2010)	pubmed:20972448|doi:10.1038/nsmb.1931|imex:IM-16072	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15887025|imex:IM-16072-10|dip:DIP-186941E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933	rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606	rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090	rigid:Iuinq9T7y8ev+1CvdtPhYIUvlZw	false	binding-associated region:1-180	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)