#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q10589 uniprotkb:Q10589 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Yang et al. (2010) pubmed:20940320|doi:10.1073/pnas.1011485107|imex:IM-17106 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15884134|imex:IM-17106-1|dip:DIP-135032E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rigid:EZEQ1la/YcfrGm5DnS5ukS7eks8 false binding-associated region:47-161 binding-associated region:47-161 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q10589 uniprotkb:Q10589 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Yang et al. (2010) pubmed:20940320|doi:10.1073/pnas.1011485107|imex:IM-17106 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15884156|imex:IM-17106-2|dip:DIP-135032E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rigid:EZEQ1la/YcfrGm5DnS5ukS7eks8 false binding-associated region:47-161 binding-associated region:47-161 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q10589 uniprotkb:Q10589 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Yang et al. (2010) pubmed:20940320|doi:10.1073/pnas.1011485107|imex:IM-17106 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0195"(covalent binding) psi-mi:"MI:0465"(DIP) intact:EBI-15884174|imex:IM-17106-3|dip:DIP-135032E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rigid:EZEQ1la/YcfrGm5DnS5ukS7eks8 false binding-associated region:45-155|his tag:c-c binding-associated region:45-155|his tag:c-c - 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q10589 uniprotkb:Q10589 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:"MI:0067"(light scattering) Yang et al. (2010) pubmed:20940320|doi:10.1073/pnas.1011485107|imex:IM-17106 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15884194|imex:IM-17106-4|dip:DIP-135032E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rigid:EZEQ1la/YcfrGm5DnS5ukS7eks8 false binding-associated region:47-161 binding-associated region:47-161 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q10589 uniprotkb:Q10589 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Yang et al. (2010) pubmed:20940320|doi:10.1073/pnas.1011485107|imex:IM-17106 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15884212|imex:IM-17106-5|dip:DIP-135032E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rigid:EZEQ1la/YcfrGm5DnS5ukS7eks8 false binding-associated region:47-161 binding-associated region:47-161 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)