#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9JMB7	uniprotkb:Q78PY7	intact:EBI-8573121|ensembl:ENSMUSP00000083222|intact:UNK-5550589|uniprotkb:A1L325|uniprotkb:A1L324|uniprotkb:Q6NXX0	intact:EBI-529864|uniprotkb:Q3TT46|uniprotkb:Q922L5|uniprotkb:Q9R0S1|ensembl:ENSMUSP00000001460	psi-mi:piwl1_mouse(display_long)|uniprotkb:Piwil1(gene name)|psi-mi:Piwil1(display_short)|uniprotkb:Miwi(gene name synonym)	psi-mi:snd1_mouse(display_long)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:Snd1(gene name)|psi-mi:Snd1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2010)	pubmed:20937909|doi:10.1073/pnas.1013106107|imex:IM-17101	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15883615|imex:IM-17101-1|dip:DIP-188068E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006504381.1|ensembl:ENSMUSG00000029423(gene)|ensembl:ENSMUST00000086056(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033391"(chromatoid body)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0097433"(dense body)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1905538"(polysome binding)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR031320|interpro:IPR031326|interpro:IPR036085|interpro:IPR036397|mint:Q9JMB7|rcsb pdb:2XFM|rcsb pdb:4P1Z|refseq:NP_067286.1|dip:DIP-59456N	refseq:NP_062750.2|dip:DIP-32118N|ensembl:ENSMUSG00000001424(gene)|ensembl:ENSMUST00000001460(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q78PY7|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")	psi-mi:"MI:0465"(dip)	comment:mint|function:"Probable component of some RISC complex (RNA-induced silencing), which plays a role in spermatogenesis and in germ cell production, proliferation and maintenance. RISC complexes mediate RNA cleavage and translational silencing. Overexpression may cause malignant germline development. May be associated with proliferating activity of cancer cells. When suppressed, inhibits the growth of gastric cancer cells and induced cell cycle arrest in G2/M phase. Inhibits endoribonuclease DICER1 activity"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/06	2017/08/10	rogid:WuQtdXXnFsLsc0HQKeK7k5wPa0I10090	rogid:cqMQzuPhE4OOYZg5AuBiYjoHYjI10090	rigid:DCag4IujV8E0vTE80319x/fcVwE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96J94	uniprotkb:Q7KZF4	intact:EBI-527417|uniprotkb:O95404|uniprotkb:Q8NA60|uniprotkb:Q8TBY5|uniprotkb:Q96JD5|uniprotkb:A4F266|ensembl:ENSP00000245255|ensembl:ENSP00000481042	intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0	psi-mi:piwl1_human(display_long)|uniprotkb:PIWIL1(gene name)|psi-mi:PIWIL1(display_short)|uniprotkb:HIWI(gene name synonym)	psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Liu et al. (2010)	pubmed:20937909|doi:10.1073/pnas.1013106107|imex:IM-17101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15883633|imex:IM-17101-2|dip:DIP-188069E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-33534N|refseq:NP_001177900.1|refseq:NP_004755.2|refseq:XP_011537304.1|refseq:XP_011537305.1|refseq:XP_011537306.1|rcsb pdb:3O6E|rcsb pdb:3O7V|ensembl:ENSG00000125207(gene)|ensembl:ENSG00000275051(gene)|ensembl:ENST00000245255(transcript)|ensembl:ENST00000613226(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033391"(chromatoid body)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0097433"(dense body)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1905538"(polysome binding)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR031320|interpro:IPR031326|interpro:IPR036085|interpro:IPR036397|mint:Q96J94|rcsb pdb:2L5C|rcsb pdb:2L5D|rcsb pdb:3O3I|rcsb pdb:6PI7|reactome:R-HSA-5601884	refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:cffy1VShng63XG+ArewNgwF/RQM9606	rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606	rigid:hWizlVZUtebXt2T+MQEU+Npeqhk	false	binding-associated region:10-17	binding-associated region:650-910	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96J94	uniprotkb:Q7KZF4	intact:EBI-527417|uniprotkb:O95404|uniprotkb:Q8NA60|uniprotkb:Q8TBY5|uniprotkb:Q96JD5|uniprotkb:A4F266|ensembl:ENSP00000245255|ensembl:ENSP00000481042	intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0	psi-mi:piwl1_human(display_long)|uniprotkb:PIWIL1(gene name)|psi-mi:PIWIL1(display_short)|uniprotkb:HIWI(gene name synonym)	psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Liu et al. (2010)	pubmed:20937909|doi:10.1073/pnas.1013106107|imex:IM-17101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15883655|imex:IM-17101-3|dip:DIP-188069E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-33534N|refseq:NP_001177900.1|refseq:NP_004755.2|refseq:XP_011537304.1|refseq:XP_011537305.1|refseq:XP_011537306.1|rcsb pdb:3O6E|rcsb pdb:3O7V|ensembl:ENSG00000125207(gene)|ensembl:ENSG00000275051(gene)|ensembl:ENST00000245255(transcript)|ensembl:ENST00000613226(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033391"(chromatoid body)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0097433"(dense body)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1905538"(polysome binding)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR031320|interpro:IPR031326|interpro:IPR036085|interpro:IPR036397|mint:Q96J94|rcsb pdb:2L5C|rcsb pdb:2L5D|rcsb pdb:3O3I|rcsb pdb:6PI7|reactome:R-HSA-5601884	refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:cffy1VShng63XG+ArewNgwF/RQM9606	rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606	rigid:hWizlVZUtebXt2T+MQEU+Npeqhk	false	binding-associated region:2-9	binding-associated region:650-910	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-15883676	uniprotkb:Q7KZF4	dip:DIP-59457N	intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0	psi-mi:h3-11(display_short)|psi-mi:EBI-15883676(display_long)	psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Liu et al. (2010)	pubmed:20937909|doi:10.1073/pnas.1013106107|imex:IM-17101	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15883680|imex:IM-17101-4|dip:DIP-188070E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:R7AfOIQ+A+Xaw1/P/wtV6rm8XnY-2	rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606	rigid:TOyimb7dnqXKdXYpRLyBDeMaPCY	false	dimethylated L-arginine:2-2	binding-associated region:650-910	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96J94	uniprotkb:Q7KZF4	intact:EBI-527417|uniprotkb:O95404|uniprotkb:Q8NA60|uniprotkb:Q8TBY5|uniprotkb:Q96JD5|uniprotkb:A4F266|ensembl:ENSP00000245255|ensembl:ENSP00000481042	intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0	psi-mi:piwl1_human(display_long)|uniprotkb:PIWIL1(gene name)|psi-mi:PIWIL1(display_short)|uniprotkb:HIWI(gene name synonym)	psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Liu et al. (2010)	pubmed:20937909|doi:10.1073/pnas.1013106107|imex:IM-17101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15883701|imex:IM-17101-5|dip:DIP-188069E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-33534N|refseq:NP_001177900.1|refseq:NP_004755.2|refseq:XP_011537304.1|refseq:XP_011537305.1|refseq:XP_011537306.1|rcsb pdb:3O6E|rcsb pdb:3O7V|ensembl:ENSG00000125207(gene)|ensembl:ENSG00000275051(gene)|ensembl:ENST00000245255(transcript)|ensembl:ENST00000613226(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033391"(chromatoid body)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0097433"(dense body)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1905538"(polysome binding)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR031320|interpro:IPR031326|interpro:IPR036085|interpro:IPR036397|mint:Q96J94|rcsb pdb:2L5C|rcsb pdb:2L5D|rcsb pdb:3O3I|rcsb pdb:6PI7|reactome:R-HSA-5601884	refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N	psi-mi:"MI:0465"(dip)	-	-	comment:Deletion of region 801-910 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:cffy1VShng63XG+ArewNgwF/RQM9606	rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606	rigid:hWizlVZUtebXt2T+MQEU+Npeqhk	false	binding-associated region:2-17	binding-associated region:650-910|mutation disrupting interaction:768-768|mutation decreasing interaction:768-768|mutation decreasing interaction:740-740|mutation decreasing interaction strength:746-746|mutation decreasing interaction:763-763|mutation decreasing interaction:766-766|necessary binding region:650-699	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96J94	uniprotkb:Q7KZF4	intact:EBI-527417|uniprotkb:O95404|uniprotkb:Q8NA60|uniprotkb:Q8TBY5|uniprotkb:Q96JD5|uniprotkb:A4F266|ensembl:ENSP00000245255|ensembl:ENSP00000481042	intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0	psi-mi:piwl1_human(display_long)|uniprotkb:PIWIL1(gene name)|psi-mi:PIWIL1(display_short)|uniprotkb:HIWI(gene name synonym)	psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Liu et al. (2010)	pubmed:20937909|doi:10.1073/pnas.1013106107|imex:IM-17101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15883769|imex:IM-17101-7|dip:DIP-188069E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-33534N|refseq:NP_001177900.1|refseq:NP_004755.2|refseq:XP_011537304.1|refseq:XP_011537305.1|refseq:XP_011537306.1|rcsb pdb:3O6E|rcsb pdb:3O7V|ensembl:ENSG00000125207(gene)|ensembl:ENSG00000275051(gene)|ensembl:ENST00000245255(transcript)|ensembl:ENST00000613226(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033391"(chromatoid body)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0097433"(dense body)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1905538"(polysome binding)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR031320|interpro:IPR031326|interpro:IPR036085|interpro:IPR036397|mint:Q96J94|rcsb pdb:2L5C|rcsb pdb:2L5D|rcsb pdb:3O3I|rcsb pdb:6PI7|reactome:R-HSA-5601884	refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:cffy1VShng63XG+ArewNgwF/RQM9606	rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606	rigid:hWizlVZUtebXt2T+MQEU+Npeqhk	false	binding-associated region:2-17	binding-associated region:650-910	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96J94	uniprotkb:Q9Y2W6-2	intact:EBI-527417|uniprotkb:O95404|uniprotkb:Q8NA60|uniprotkb:Q8TBY5|uniprotkb:Q96JD5|uniprotkb:A4F266|ensembl:ENSP00000245255|ensembl:ENSP00000481042	intact:EBI-15883741|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718	psi-mi:piwl1_human(display_long)|uniprotkb:PIWIL1(gene name)|psi-mi:PIWIL1(display_short)|uniprotkb:HIWI(gene name synonym)	psi-mi:q9y2w6-2(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Liu et al. (2010)	pubmed:20937909|doi:10.1073/pnas.1013106107|imex:IM-17101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15883748|imex:IM-17101-6|dip:DIP-188072E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-33534N|refseq:NP_001177900.1|refseq:NP_004755.2|refseq:XP_011537304.1|refseq:XP_011537305.1|refseq:XP_011537306.1|rcsb pdb:3O6E|rcsb pdb:3O7V|ensembl:ENSG00000125207(gene)|ensembl:ENSG00000275051(gene)|ensembl:ENST00000245255(transcript)|ensembl:ENST00000613226(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033391"(chromatoid body)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0097433"(dense body)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1905538"(polysome binding)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR031320|interpro:IPR031326|interpro:IPR036085|interpro:IPR036397|mint:Q96J94|rcsb pdb:2L5C|rcsb pdb:2L5D|rcsb pdb:3O3I|rcsb pdb:6PI7|reactome:R-HSA-5601884	ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|ensembl:ENST00000368824(transcript)|intact:EBI-12842466(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:cffy1VShng63XG+ArewNgwF/RQM9606	rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606	rigid:rxIIWheyj7FeOJ0ofOWxM4ooOxU	false	binding-associated region:2-17	binding-associated region:290-530	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-15883790	uniprotkb:Q7KZF4	dip:DIP-59458N	intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0	psi-mi:h4-4(display_short)|psi-mi:EBI-15883790(display_long)	psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Liu et al. (2010)	pubmed:20937909|doi:10.1073/pnas.1013106107|imex:IM-17101	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15883793|imex:IM-17101-8|dip:DIP-188071E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:GOwiApYITpdL18yVHN9FEb93sfI-2	rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606	rigid:pscjTqJ1JSB24mqE2TUpq+/IX1c	false	dimethylated L-arginine:3-3	binding-associated region:650-910	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)