#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P36873 uniprotkb:Q14684 intact:EBI-356283|ensembl:ENSP00000335084 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym) psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686916|imex:IM-26310-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 - - - figure legend:Fig 1F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/07 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rigid:HYF3dsivfyAxVKoKd2qnrO39K+I false - green fluorescent protein tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62140 uniprotkb:Q14684 intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short) psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686923|imex:IM-26310-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 - - - figure legend:Fig 1Fi|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/07 rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rigid:1xheyn1TPfNedzEE0vjEQeSgZVQ false - green fluorescent protein tag:n-n|mutation disrupting interaction strength:684-684,686-686 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14684 uniprotkb:P36873 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356283|ensembl:ENSP00000335084 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16687353|imex:IM-26310-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N go:"GO:0005730"(nucleolus)|go:"GO:0005654"(nucleoplasm) - - figure legend:Fig 7A -lower image|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/08 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rigid:HYF3dsivfyAxVKoKd2qnrO39K+I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14684 uniprotkb:Q14684 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16687353|imex:IM-26310-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0005730"(nucleolus)|go:"GO:0005654"(nucleoplasm) - - figure legend:Fig 7A -lower image|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/08 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rigid:HYF3dsivfyAxVKoKd2qnrO39K+I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14684 uniprotkb:P46087 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356811|uniprotkb:A1A4Z3|uniprotkb:Q0P5S5|uniprotkb:Q58F30|uniprotkb:B3KPD6|uniprotkb:Q05BA7|uniprotkb:Q3KQS4|ensembl:ENSP00000313272|ensembl:ENSP00000444437 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nop2_human(display_long)|uniprotkb:NOP2(gene name)|psi-mi:NOP2(display_short)|uniprotkb:NSUN1(gene name synonym)|uniprotkb:Proliferating-cell nucleolar antigen p120(gene name synonym)|uniprotkb:Proliferation-associated nucleolar protein p120(gene name synonym)|uniprotkb:NOL1(gene name synonym)|uniprotkb:Nucleolar protein 2 homolog(gene name synonym)|uniprotkb:Nucleolar protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16687362|imex:IM-26310-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001028886.1|refseq:NP_006161.2|refseq:NP_001245237.1|refseq:NP_001245238.1|refseq:NP_001245239.1|refseq:XP_005253748.1|ensembl:ENSG00000111641(gene)|ensembl:ENST00000322166(transcript)|ensembl:ENST00000537442(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009383"("rRNA (cytosine-C5-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR011023(Nop2p)|interpro:IPR012586(P120R)|interpro:IPR018314|interpro:IPR023267|interpro:IPR023273|interpro:IPR029063|interpro:IPR031341|mint:P46087|reactome:R-HSA-6790901|reactome:R-HSA-8869496 - - - figure legend:Fig 7A- top image|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/08 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:CvYaCDv8N8OvS0lPFy8jFEFaOTA9606 rigid:r85uEieMRDjXAKWbsFF38npMm64 false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14684 uniprotkb:P06748 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16687362|imex:IM-26310-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496 - - - figure legend:Fig 7A- top image|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/08 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 rigid:r85uEieMRDjXAKWbsFF38npMm64 false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14684 uniprotkb:P56182 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16687400|imex:IM-26310-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1 - - - figure legend:Fig 7B-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/08 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606 rigid:cRngG2KjfHW6qN98xtuSWgzg7xc false - green fluorescent protein tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P22087 uniprotkb:Q14684 intact:EBI-358318|uniprotkb:O75259|uniprotkb:Q6IAT5|uniprotkb:Q9UPI6|ensembl:ENSP00000221801|ensembl:ENSP00000487390|uniprotkb:B5BUE8 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 psi-mi:fbrl_human(display_long)|uniprotkb:FBL(gene name)|psi-mi:FBL(display_short)|uniprotkb:FIB1(gene name synonym)|uniprotkb:FLRN(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)|uniprotkb:34 kDa nucleolar scleroderma antigen(gene name synonym)|uniprotkb:U6 snRNA 2'-O-methyltransferase fibrillarin(gene name synonym) psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16687411|imex:IM-26310-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001427.2|ensembl:ENSG00000105202(gene)|ensembl:ENSG00000280548(gene)|ensembl:ENST00000221801(transcript)|ensembl:ENST00000625241(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0001652"(granular component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|mint:P22087|rcsb pdb:2IPX|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-27569N refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 - - - figure legend:Fig 7B-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/08 rogid:8m8FDRSxGNKNXpJMcWWbcHL3uss9606 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rigid:KmPpr/ArVtalfTRggw66ePv2X/s false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P61353 uniprotkb:Q14684 intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym) psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16687417|imex:IM-26310-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 - - - figure legend:Fig 7B-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/08 rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rigid:54m97Ywxs2atAG+PMkXcF6Bg6yI false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P46777 uniprotkb:Q14684 intact:EBI-358018|ensembl:ENSP00000359345|uniprotkb:Q53HH6|uniprotkb:Q9H3F4|uniprotkb:Q32LZ3 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 psi-mi:rl5_human(display_long)|uniprotkb:RPL5(gene name)|psi-mi:RPL5(display_short)|uniprotkb:Large ribosomal subunit protein uL18(gene name synonym)|uniprotkb:MSTP030(orf name) psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16687423|imex:IM-26310-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|ensembl:ENSG00000122406(gene)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENST00000370321(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|refseq:NP_000960.2|dip:DIP-31152N|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P46777|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 - - - figure legend:Fig 7B-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/08 rogid:rs+zAc+IPrEqv7DHNcy2GIkQkfY9606 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rigid:RTBo7swcSHb3GFt6IOmDMHzxug0 false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P61353 uniprotkb:P36873 intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587 intact:EBI-356283|ensembl:ENSP00000335084 psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym) psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16687429|imex:IM-26310-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N go:"GO:0005730"(nucleolus)|go:"GO:0005654"(nucleoplasm) - - figure legend:Fig 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/08 rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rigid:bi4AcESK4f2gQrtKgokho8YRI2U false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P61353 uniprotkb:Q14684 intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym) psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16687429|imex:IM-26310-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0005730"(nucleolus)|go:"GO:0005654"(nucleoplasm) - - figure legend:Fig 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/08 rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rigid:bi4AcESK4f2gQrtKgokho8YRI2U false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14684 uniprotkb:P62136 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:"MI:0047"(far western blotting) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16686938|imex:IM-26310-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) - - - figure legend:Fig 1G|comment:weak binding|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/10/19 2017/12/08 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 rigid:pe6NykFtMPUa1CB201BrZUUeMjY false his tag:?-?|mutation disrupting interaction strength:684-684,686-686 tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:Q14684 uniprotkb:P36873 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356283|ensembl:ENSP00000335084 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym) psi-mi:"MI:0047"(far western blotting) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16686948|imex:IM-26310-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N - - - figure legend:Fig 1Gi|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/10/19 2017/12/08 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rigid:HYF3dsivfyAxVKoKd2qnrO39K+I false his tag:?-?|mutation disrupting interaction strength:684-684,686-686 tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:Q14684 uniprotkb:P36873 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356283|ensembl:ENSP00000335084 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16686964|imex:IM-26310-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N go:"GO:0005730"(nucleolus) - - figure legend:Fig 3 C/D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2018/06/18 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rigid:HYF3dsivfyAxVKoKd2qnrO39K+I false mutation disrupting interaction strength:684-684,686-686|mcherry fluorescent protein tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q14684 uniprotkb:Q6P2Q9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-538479|uniprotkb:O14547|uniprotkb:O75965|ensembl:ENSP00000304350|ensembl:ENSP00000460348|ensembl:ENSP00000479194|ensembl:ENSP00000488611 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:prp8_human(display_long)|uniprotkb:Splicing factor Prp8(gene name synonym)|uniprotkb:PRP8 homolog(gene name synonym)|uniprotkb:220 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:p220(gene name synonym)|uniprotkb:PRPC8(gene name synonym)|uniprotkb:PRPF8(gene name)|psi-mi:PRPF8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006436.3|ensembl:ENSG00000174231(gene)|ensembl:ENSG00000274442(gene)|ensembl:ENST00000304992(transcript)|ensembl:ENST00000572621(transcript)|ensembl:ENST00000614672(transcript)|ensembl:ENST00000634039(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|mint:Q6P2Q9|rcsb pdb:3E9L|rcsb pdb:3ENB|rcsb pdb:3JCR|rcsb pdb:3LRU|rcsb pdb:4JK7|rcsb pdb:4JK8|rcsb pdb:4JK9|rcsb pdb:4JKA|rcsb pdb:4JKB|rcsb pdb:4JKC|rcsb pdb:4JKD|rcsb pdb:4JKE|rcsb pdb:4JKF|rcsb pdb:4JKG|rcsb pdb:4JKH|rcsb pdb:4KIT|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5XJC|dip:DIP-29614N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:I0ot8b3pvieXRI66omFm145sGVA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BUQ8 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-540096|uniprotkb:B2R600|uniprotkb:O43188|uniprotkb:B4DH15|intact:EBI-2557638|ensembl:ENSP00000310723 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx23_human(display_long)|uniprotkb:DEAD box protein 23(gene name synonym)|uniprotkb:100 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:U5-100kD(gene name synonym)|uniprotkb:PRP28 homolog(gene name synonym)|uniprotkb:DDX23(gene name)|psi-mi:DDX23(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004809.2|ensembl:ENSG00000174243(gene)|ensembl:ENST00000308025(transcript)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9BUQ8|rcsb pdb:3JCR|rcsb pdb:4NHO|rcsb pdb:6AH0|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-34974N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:tEDp48akFaCjRBBXB4jtyrAsLQ89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P35250 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8N726 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-625922|uniprotkb:Q13195|uniprotkb:Q13399|uniprotkb:Q16360|uniprotkb:Q7KZR9|ensembl:ENSP00000432664|ensembl:ENSP00000462950|uniprotkb:D3DRK2 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:arf_human(display_long)|uniprotkb:p14ARF(gene name synonym)|uniprotkb:CDKN2A(gene name)|psi-mi:CDKN2A(display_short)|uniprotkb:CDKN2(gene name synonym)|uniprotkb:MLM(gene name synonym)|uniprotkb:Alternative reading frame(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000147889(gene)|ensembl:ENST00000530628(transcript)|ensembl:ENST00000579755(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0050821"(protein stabilization)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090398"(cellular senescence)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR010868(Cyclin-dependent kinase inhibitor 2a p19Arf, N-terminal)|mint:Q8N726|reactome:R-HSA-111471|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-6804757|reactome:R-HSA-69541|reactome:R-HSA-8941858|reactome:R-HSA-9645722|reactome:R-HSA-9646303|reactome:R-HSA-9646304|refseq:NP_478102.2|dip:DIP-24171N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:zdbvJmkrI/zJFL+Enq5jTM1Csdw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BSC4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-7001376|uniprotkb:Q53RC9|uniprotkb:Q9H855|uniprotkb:Q96TA5|uniprotkb:Q9H7Y7|uniprotkb:A8K3R5|intact:MINT-3060916|uniprotkb:B4DLV0|ensembl:ENSP00000371101 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nol10_human(display_long)|uniprotkb:NOL10(gene name)|psi-mi:NOL10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_079170.2|refseq:NP_001248323.1|refseq:NP_001248321.1|ensembl:ENSG00000115761(gene)|ensembl:ENST00000381685(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR012580(NUC153)|interpro:IPR036322|interpro:IPR040382|mint:Q9BSC4 - - comment:mint figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:PiblslntTRSvRQnk82fSgtVJbXE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96P11 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-7950892|uniprotkb:B3KX04|uniprotkb:B4DP79|uniprotkb:G3V0G9|uniprotkb:Q9NW70|uniprotkb:Q96HT9|intact:MINT-5009481|uniprotkb:Q6ZUI8|ensembl:ENSP00000252594 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nsun5_human(display_long)|uniprotkb:NSUN5(gene name)|psi-mi:NSUN5(display_short)|uniprotkb:WBSCR20(gene name synonym)|uniprotkb:WBSCR20A(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 5(gene name synonym)|uniprotkb:NOL1-related protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 20A protein(gene name synonym)|uniprotkb:NSUN5A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001161820.1|refseq:NP_683759.1|refseq:NP_001161819.1|refseq:NP_060514.1|ensembl:ENSG00000130305(gene)|ensembl:ENST00000252594(transcript)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0009383"("rRNA (cytosine-C5-)-methyltransferase activity")|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031641"(regulation of myelination)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0050890"(cognition)|go:"GO:0070475"(rRNA base methylation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR029063|rcsb pdb:2B9E - - function:May have S-adenosyl-L-methionine-dependent methyl-transferase activity|comment:mint|comment:homomint figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:XlSqjJZMz+T3RVbS87HQn7wkRjk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y3A4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-7223720|uniprotkb:B2RBG4|uniprotkb:Q8NEY6|uniprotkb:Q8IVY0|intact:MINT-2823375|intact:UNK-5358198|uniprotkb:Q5JZ94|uniprotkb:Q6P4B5|uniprotkb:Q0VAD0|uniprotkb:Q8N5Q3|uniprotkb:Q9Y3H5|uniprotkb:A4FTX2|intact:UNK-5480409|uniprotkb:Q8IVR9|ensembl:ENSP00000321449 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rrp7a_human(display_long)|uniprotkb:CGI-96(orf name)|uniprotkb:RRP7A(gene name)|psi-mi:RRP7A(display_short)|uniprotkb:Gastric cancer antigen Zg14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_056518.2|ensembl:ENSG00000189306(gene)|ensembl:ENST00000323013(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024326|interpro:IPR034890|interpro:IPR035979|interpro:IPR040446|interpro:IPR040447|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - comment:mint|comment:homomint figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:8ydFaLpL9ttv+9iZyvaQf3GPWXg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P48651 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-8652106|uniprotkb:B4DE85|uniprotkb:E5RFC5|uniprotkb:Q9BUQ5|intact:MINT-8163942|ensembl:ENSP00000430548 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ptss1_human(display_long)|uniprotkb:PTDSS1(gene name)|psi-mi:PTDSS1(display_short)|uniprotkb:KIAA0024(gene name synonym)|uniprotkb:PSSA(gene name synonym)|uniprotkb:Serine-exchange enzyme I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001277154.1|refseq:NP_055569.1|ensembl:ENSG00000156471(gene)|ensembl:ENST00000517309(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0106245"(L-serine-phosphatidylethanolamine phosphatidyltransferase activity)|go:"GO:0106258"(L-serine-phosphatidylcholine phosphatidyltransferase activity)|interpro:IPR004277(Phosphatidyl serine synthase)|mint:P48651|reactome:R-HSA-1483101 - - comment:mint figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:FDSRlCB+/84r8jXnvywHmzAqq9s9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96G21 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-8641721|ensembl:ENSP00000259239|intact:MINT-3052989|intact:MINT-8163231|uniprotkb:Q3ZTT3 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:imp4_human(display_long)|uniprotkb:BXDC4(gene name synonym)|uniprotkb:IMP4(gene name)|psi-mi:IMP4(display_short)|uniprotkb:Brix domain-containing protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000136718(gene)|ensembl:ENST00000259239(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030684"(preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR044281|mint:Q96G21|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_001307233.1|refseq:NP_001307234.1|refseq:NP_001307235.1|refseq:NP_001307236.1|refseq:NP_001307238.1|refseq:NP_001307239.1|refseq:NP_001307240.1|refseq:NP_219484.1 - - function:"Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing"|comment:mint figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:O220J7eEl0dgQmdVSttk/TMtY4Y9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NWT1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-7641942|ensembl:ENSP00000368887|ensembl:ENSP00000496482|uniprotkb:Q5T4J2|uniprotkb:Q96T87|intact:MINT-3057412|uniprotkb:Q96QJ8 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pk1ip_human(display_long)|uniprotkb:PAK1IP1(gene name)|psi-mi:PAK1IP1(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:WDR84(gene name synonym)|uniprotkb:PAK1-interacting protein 1(gene name synonym)|uniprotkb:PAK/PLC-interacting protein 1(gene name synonym)|uniprotkb:WD repeat-containing protein 84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000111845(gene)|ensembl:ENSG00000285226(gene)|ensembl:ENST00000379568(transcript)|ensembl:ENST00000644756(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NWT1|refseq:NP_060376.2 - - comment:mint|function:Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42 figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:nAGXksSPZ1aDBtcWOP59JX/lQGA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P28066 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q01780 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P83881 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1054835|uniprotkb:P09896|uniprotkb:P10661|uniprotkb:Q5J9I6|uniprotkb:Q08ES5|ensembl:ENSP00000446503 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl36a_human(display_long)|uniprotkb:60S ribosomal protein L44(gene name synonym)|uniprotkb:Cell migration-inducing gene 6 protein(gene name synonym)|uniprotkb:RPL36A(gene name)|psi-mi:RPL36A(display_short)|uniprotkb:MIG6(orf name)|uniprotkb:RPL44(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 15 protein(gene name synonym)|uniprotkb:GIG15(orf name)|uniprotkb:Large ribosomal subunit protein eL42(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_066357.2|ensembl:ENSG00000241343(gene)|ensembl:ENST00000553110(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P83881|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:OrRyOEVJZbSdttK93KL/DS5YxJ89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62979 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NY93 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-372376|uniprotkb:Q9H9I8|intact:EBI-1051948|uniprotkb:Q6IAE2|uniprotkb:A4D2K9|ensembl:ENSP00000258772|uniprotkb:C9JV95 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx56_human(display_long)|uniprotkb:DDX56(gene name)|psi-mi:DDX56(display_short)|uniprotkb:DDX21(gene name synonym)|uniprotkb:DEAD box protein 56(gene name synonym)|uniprotkb:ATP-dependent 61 kDa nucleolar RNA helicase(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym)|uniprotkb:NOH61(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_061955.1|ensembl:ENSG00000136271(gene)|ensembl:ENST00000258772(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9NY93|refseq:NP_001244118.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Pfa1hEJ7HnBZtSO4aZ2xRixpldc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UNL2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1043938|uniprotkb:Q549M4|ensembl:ENSP00000265044|uniprotkb:B2R7D0|uniprotkb:D3DNK5|uniprotkb:B4E2P2 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ssrg_human(display_long)|uniprotkb:Signal sequence receptor subunit gamma(gene name synonym)|uniprotkb:SSR3(gene name)|psi-mi:SSR3(display_short)|uniprotkb:TRAPG(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_009038.1|ensembl:ENSG00000114850(gene)|ensembl:ENST00000265044(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009779(Translocon-associated, gamma subunit)|mint:Q9UNL2|reactome:R-HSA-1799339|refseq:NP_001295126.1|refseq:NP_001295133.1|refseq:NP_001295134.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Fb918T41oaTpc+kzNIygp1h1tlo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14839 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O14646 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1560858|uniprotkb:Q17RZ3|ensembl:ENSP00000284049|ensembl:ENSP00000483667 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:chd1_human(display_long)|uniprotkb:ATP-dependent helicase CHD1(gene name synonym)|uniprotkb:CHD1(gene name)|psi-mi:CHD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001261.2|refseq:XP_005271924.1|dip:DIP-38922N|ensembl:ENSG00000153922(gene)|ensembl:ENST00000284049(transcript)|ensembl:ENST00000614616(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR025260|interpro:IPR027417|interpro:IPR038718|interpro:IPR040793|mint:O14646|rcsb pdb:2B2T|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2B2Y|rcsb pdb:2N39|rcsb pdb:4B4C|rcsb pdb:4NW2|rcsb pdb:4O42|rcsb pdb:5AFW|reactome:R-HSA-9018519 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:KzH9c8MyoQh0Ph+KwSUktSa5qWM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O76071 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BW27 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-716392|intact:EBI-2563151|uniprotkb:Q9H9U1|uniprotkb:Q8NDI4|uniprotkb:B4DMQ3|uniprotkb:B4DPW1|ensembl:ENSP00000245544 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nup85_human(display_long)|uniprotkb:PCNT1(gene name synonym)|uniprotkb:Nucleoporin Nup85(gene name synonym)|uniprotkb:85 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup75(gene name synonym)|uniprotkb:Pericentrin-1(gene name synonym)|uniprotkb:FROUNT(gene name synonym)|uniprotkb:NUP85(gene name)|psi-mi:NUP85(display_short)|uniprotkb:NUP75(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_079120.1|refseq:NP_001290205.1|ensembl:ENSG00000125450(gene)|ensembl:ENST00000245544(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0072006"(nephron development)|interpro:IPR011502(Nucleoporin, Nup85-like)|mint:Q9BW27|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:MWeo3e2aXVKhP1gFV8ZZrgyFSeI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q5SSJ5 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2880687|ensembl:ENSP00000312625|ensembl:ENSP00000403039|uniprotkb:Q5SWC6|uniprotkb:Q6PIM9|uniprotkb:B3KMZ8|uniprotkb:A8K5D7|uniprotkb:Q8NDF0|uniprotkb:Q05BI0|uniprotkb:B4E210|uniprotkb:A6NI71|uniprotkb:Q9UHY0|uniprotkb:Q5SSJ6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:hp1b3_human(display_long)|uniprotkb:HP1BP3(gene name)|psi-mi:HP1BP3(display_short)|uniprotkb:Protein HP1-BP74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000127483(gene)|ensembl:ENST00000312239(transcript)|ensembl:ENST00000438032(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097298"(regulation of nucleus size)|interpro:IPR005818(Histone H1/H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390|mint:Q5SSJ5|rcsb pdb:2RQP|go:"GO:0005694"(chromosome)|refseq:XP_016856882.1|refseq:XP_016856883.1|refseq:XP_011539834.1|refseq:XP_011539835.1|refseq:XP_011539836.1|refseq:NP_057371.2|refseq:XP_005245932.1|refseq:XP_005245933.1|refseq:XP_005245934.1|refseq:XP_005245935.1|refseq:XP_005245936.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:kLFithZZv+Qn9YLElEnX81awKDw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q09161 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8NEJ9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-9995414|uniprotkb:A8K760|uniprotkb:Q9Y400|ensembl:ENSP00000386134 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ngdn_human(display_long)|uniprotkb:NGDN(gene name)|psi-mi:NGDN(display_short)|uniprotkb:C14orf120(gene name synonym)|uniprotkb:Centromere accumulated nuclear protein 1(gene name synonym)|uniprotkb:EIF4E-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001036100.1|refseq:NP_056329.1|ensembl:ENSG00000129460(gene)|ensembl:ENST00000408901(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006417"(regulation of translation)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032040"(small-subunit processome)|interpro:IPR007146(Small-subunit processome, Utp3)|mint:Q8NEJ9 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:dzn7QntKCrb97VLlmUMizp+0CV49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O15213 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-9995439|uniprotkb:A6NDP5|uniprotkb:Q5HYZ0|uniprotkb:Q5STK5|uniprotkb:Q5STR3|ensembl:ENSP00000363746|ensembl:ENSP00000372695|ensembl:ENSP00000399454|ensembl:ENSP00000402869|ensembl:ENSP00000405614 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:wdr46_human(display_long)|uniprotkb:WDR46(gene name)|psi-mi:WDR46(display_short)|uniprotkb:BING4(gene name synonym)|uniprotkb:C6orf11(gene name synonym)|uniprotkb:WD repeat-containing protein BING4(gene name synonym)|uniprotkb:FP221(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001157739.1|refseq:NP_005443.3|ensembl:ENSG00000204221(gene)|ensembl:ENSG00000206284(gene)|ensembl:ENSG00000226916(gene)|ensembl:ENSG00000227057(gene)|ensembl:ENSG00000236222(gene)|ensembl:ENST00000374617(transcript)|ensembl:ENST00000383208(transcript)|ensembl:ENST00000432609(transcript)|ensembl:ENST00000432933(transcript)|ensembl:ENST00000457382(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR040315|mint:O15213|reactome:R-HSA-6790901|reactome:R-HSA-6791226|interpro:IPR012952(BING4, C-terminal) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:BYhBAazSJnKN4c7RgWU2WygOk4o9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UIG0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-927482|uniprotkb:O95039|uniprotkb:O95247|uniprotkb:O95277|uniprotkb:B9EGK3|uniprotkb:Q6P1K4|uniprotkb:Q86UJ6|uniprotkb:D3DXE9|ensembl:ENSP00000342434|ensembl:ENSP00000385442 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:baz1b_human(display_long)|uniprotkb:BAZ1B(gene name)|psi-mi:BAZ1B(display_short)|uniprotkb:WBSC10(gene name synonym)|uniprotkb:WBSCR9(gene name synonym)|uniprotkb:WSTF(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 9 protein(gene name synonym)|uniprotkb:Williams syndrome transcription factor(gene name synonym)|uniprotkb:WBSCR10(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 10 protein(gene name synonym)|uniprotkb:Bromodomain adjacent to zinc finger domain protein 1B(gene name synonym)|uniprotkb:hWALp2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_115784.1|refseq:XP_016868262.1|dip:DIP-35642N|ensembl:ENSG00000009954(gene)|ensembl:ENST00000339594(transcript)|ensembl:ENST00000404251(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0035173"(histone kinase activity)|go:"GO:0042393"(histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037375|mint:Q9UIG0|rcsb pdb:1F62|rcsb pdb:5NNF|reactome:R-HSA-5250924|reactome:R-HSA-5693565 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:1GTflhs9UUxTv4SPOYPKmuKAtSQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62304 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14865 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1210388|uniprotkb:B4DLB3|uniprotkb:Q05DG6|uniprotkb:Q32Q59|uniprotkb:Q6NZ42|uniprotkb:Q5VST4|uniprotkb:Q7Z3M4|uniprotkb:Q8N421|uniprotkb:Q9H786|ensembl:ENSP00000279873 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ari5b_human(display_long)|uniprotkb:ARID5B(gene name)|psi-mi:ARID5B(display_short)|uniprotkb:DESRT(gene name synonym)|uniprotkb:MRF2(gene name synonym)|uniprotkb:MRF1-like protein(gene name synonym)|uniprotkb:Modulator recognition factor 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_115575.1|refseq:NP_001231567.1|ensembl:ENSG00000150347(gene)|ensembl:ENST00000279873(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030325"(adrenal gland development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR030408|interpro:IPR036431|mint:Q14865|rcsb pdb:1IG6|rcsb pdb:2OEH|reactome:R-HSA-3214842|go:"GO:0005654"(nucleoplasm) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:B6FNUWNl796yE+jX/0cAknrAkuo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NU22 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1050480|uniprotkb:O15019|uniprotkb:Q5T794|ensembl:ENSP00000358400|ensembl:ENSP00000486270|ensembl:ENSP00000499843|ensembl:ENSP00000499895 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mdn1_human(display_long)|uniprotkb:MIDAS-containing protein(gene name synonym)|uniprotkb:Dynein-related AAA-ATPase MDN1(gene name synonym)|uniprotkb:MDN1(gene name)|psi-mi:MDN1(display_short)|uniprotkb:KIAA0301(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055426.1|ensembl:ENSG00000112159(gene)|ensembl:ENSG00000288121(gene)|ensembl:ENST00000369393(transcript)|ensembl:ENST00000629399(transcript)|ensembl:ENST00000672983(transcript)|ensembl:ENST00000673332(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR012099(Midasin)|interpro:IPR027417|interpro:IPR036465|interpro:IPR040848|interpro:IPR041190|mint:Q9NU22|go:"GO:0005829"(cytosol) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:/LVYhffZVpP0pYVM6hLNltoc6pY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O15260 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P04843 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H0D6 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-372110|uniprotkb:Q3L8N4|uniprotkb:Q6KGZ9|uniprotkb:Q9BQL1|uniprotkb:Q9NTW0|uniprotkb:Q9NXS6|uniprotkb:Q9UL53|ensembl:ENSP00000366396 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:xrn2_human(display_long)|uniprotkb:XRN2(gene name)|psi-mi:XRN2(display_short)|uniprotkb:DHM1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_036387.2|refseq:NP_001304889.1|ensembl:ENSG00000088930(gene)|ensembl:ENST00000377191(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR017151(5'-3' exoribonuclease 2)|interpro:IPR027073|interpro:IPR041412|mint:Q9H0D6|reactome:R-HSA-390471|reactome:R-HSA-6791226|dip:DIP-31166N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Ui0NiU+fGe68hK5CYTolkhioQbQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96KR1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2513582|ensembl:ENSP00000265069|uniprotkb:Q9Y687|uniprotkb:Q6P5A3|uniprotkb:B2RNR5|uniprotkb:Q9H6V4|uniprotkb:Q3B7X5|uniprotkb:Q05C08|uniprotkb:Q9NTI1|uniprotkb:Q86UA0|intact:EBI-2560216 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:zfr_human(display_long)|uniprotkb:ZFR(gene name)|psi-mi:ZFR(display_short)|uniprotkb:M-phase phosphoprotein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000056097(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR006561(DZF)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043519|mint:Q96KR1|ensembl:ENST00000265069(transcript)|refseq:NP_057191.2|ensembl:ENSP00000265069|dip:DIP-47293N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:UQQP+tkUcQYka9ez6rMv2F6FXFM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O00410 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q29RF7 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q7L014 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2555356|uniprotkb:Q96EI0|uniprotkb:O94894|uniprotkb:Q9Y658|ensembl:ENSP00000346236 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx46_human(display_long)|uniprotkb:KIAA0801(gene name synonym)|uniprotkb:DEAD box protein 46(gene name synonym)|uniprotkb:PRP5 homolog(gene name synonym)|uniprotkb:DDX46(gene name)|psi-mi:DDX46(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055644.2|ensembl:ENSG00000145833(gene)|ensembl:ENST00000354283(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q7L014|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|reactome:R-HSA-72163|refseq:NP_001287789.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:spn1NOUIO6XjH4RRbtPsBgR5Wk09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q969Q0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:+jT5oFy79StEavkvHz6j/36g/qg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q00610 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O00159 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-350423|uniprotkb:Q6NVJ7|intact:EBI-1045431|uniprotkb:Q86Y95|uniprotkb:Q4LE56|ensembl:ENSP00000496954 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:myo1c_human(display_long)|uniprotkb:MYO1C(gene name)|psi-mi:MYO1C(display_short)|uniprotkb:Myosin I beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0005829"(cytosol)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|refseq:NP_001074248.1|refseq:NP_001074419.1|refseq:NP_203693.3|ensembl:ENSG00000197879(gene)|ensembl:ENST00000648651(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O00159|rcsb pdb:4BYF|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-5250924|reactome:R-HSA-9662360|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|reactome:R-HSA-9662361|reactome:R-HSA-9664422|dip:DIP-33109N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:g6wQN0OVKjd3T1kOebWFcqWNzNA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96T58 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-765739|uniprotkb:Q9UQ01|uniprotkb:Q9Y556|uniprotkb:Q9H9A8|uniprotkb:Q9NWH5|intact:EBI-28975565|ensembl:ENSP00000364912 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mint_human(display_long)|uniprotkb:SPEN homolog(gene name synonym)|uniprotkb:SMART/HDAC1-associated repressor protein(gene name synonym)|uniprotkb:KIAA0929(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:SHARP(gene name synonym)|uniprotkb:SPEN(gene name)|psi-mi:SPEN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055816.2|ensembl:ENSP00000364912|dip:DIP-34569N|ensembl:ENSG00000065526(gene)|ensembl:ENST00000375759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034172|interpro:IPR034173|interpro:IPR034174|interpro:IPR034175|interpro:IPR035979|mint:Q96T58|rcsb pdb:1OW1|rcsb pdb:2RT5|rcsb pdb:4P6Q|reactome:R-HSA-9013422|go:"GO:0005654"(nucleoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:m7bdkKVATaG4dkFG/BYXRn4jOIk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14978 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-396155|uniprotkb:Q15030|intact:EBI-1055664|uniprotkb:Q9BUV3|uniprotkb:Q5VV70|ensembl:ENSP00000474710 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nolc1_human(display_long)|uniprotkb:NOLC1(gene name)|psi-mi:NOLC1(display_short)|uniprotkb:KIAA0035(gene name synonym)|uniprotkb:Nucleolar 130 kDa protein(gene name synonym)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Nucleolar phosphoprotein p130(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 13(gene name synonym)|uniprotkb:NS5ATP13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004732.2|refseq:NP_001271317.1|refseq:NP_001271318.1|ensembl:ENSG00000166197(gene)|ensembl:ENST00000605788(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0062064"(box C/D snoRNP complex binding)|go:"GO:0062065"(box H/ACA snoRNP complex binding)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|mint:Q14978 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:G3ClYMfSSjWsDzkxtahX5lLRzzQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q13247 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-745230|uniprotkb:Q13244|uniprotkb:Q13245|uniprotkb:Q96J06|uniprotkb:Q9UJB8|uniprotkb:Q9Y3N7|uniprotkb:B7Z6J3|uniprotkb:E1P5W6|ensembl:ENSP00000244020 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:srsf6_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:SRSF6(gene name)|psi-mi:SRSF6(display_short)|uniprotkb:SRP55(gene name synonym)|uniprotkb:SFRS6(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006266.2|ensembl:ENSG00000124193(gene)|ensembl:ENST00000244020(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|mint:Q13247|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:vU4nobP3g/hsgnll0mQgjJcME2k9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62314 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-372177|uniprotkb:P13641|uniprotkb:B5BTZ1|ensembl:ENSP00000300413 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:smd1_human(display_long)|uniprotkb:SNRPD1(gene name)|psi-mi:SNRPD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001278845.1|refseq:NP_008869.1|ensembl:ENSG00000167088(gene)|ensembl:ENST00000300413(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|go:"GO:0000243"(commitment complex)|interpro:IPR027141|interpro:IPR034102|mint:P62314|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|go:"GO:0000245"(spliceosomal complex assembly)|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|go:"GO:0000387"(spliceosomal snRNP assembly)|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-31207N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:bfXwsV+IOjDPCoOJOoMQgECyiII9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q6P2E9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q3SXM5 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1056703|uniprotkb:Q3SXM4|uniprotkb:Q9BY22|uniprotkb:Q8NC98|uniprotkb:D3DUL4|uniprotkb:B4DSL2|ensembl:ENSP00000219439 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:hsdl1_human(display_long)|uniprotkb:HSDL1(gene name)|psi-mi:HSDL1(display_short)|uniprotkb:SDR12C3(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 12C member 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001139523.1|refseq:NP_113651.4|refseq:XP_005256246.1|ensembl:ENSG00000103160(gene)|ensembl:ENST00000219439(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045111"(intermediate filament cytoskeleton)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:hM3wgoAPVyTT3ma1PhnK5QnOwk89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P49411 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P50402 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8NI27 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1755078|intact:EBI-2802903|uniprotkb:A6NM50|uniprotkb:Q9H8I6|uniprotkb:Q5JZ12|uniprotkb:Q6IN92|ensembl:ENSP00000245838|ensembl:ENSP00000347959 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:thoc2_human(display_long)|uniprotkb:hTREX120(gene name synonym)|uniprotkb:THOC2(gene name)|psi-mi:THOC2(display_short)|uniprotkb:CXorf3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001075019.1|ensembl:ENSG00000125676(gene)|ensembl:ENST00000245838(transcript)|ensembl:ENST00000355725(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048666"(neuron development)|go:"GO:0048699"(generation of neurons)|interpro:IPR021418|interpro:IPR021726|interpro:IPR032302|interpro:IPR040007|mint:Q8NI27|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:GJCI/aEu/upu9s/gMVJvt56PXP89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P52272 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-486809|uniprotkb:Q9Y492|uniprotkb:Q15584|uniprotkb:Q8WZ44|uniprotkb:Q96H56|uniprotkb:Q9BWL9|intact:EBI-28985795|ensembl:ENSP00000325376 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:hnrpm_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)|uniprotkb:HNRPM(gene name synonym)|uniprotkb:NAGR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005959.2|refseq:NP_112480.2|ensembl:ENSG00000099783(gene)|ensembl:ENST00000325495(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:P52272|rcsb pdb:2DGV|rcsb pdb:2DH9|rcsb pdb:2DO0|rcsb pdb:2OT8|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-29336N|ensembl:ENSP00000325376|ensembl:ENST00000348943|ensembl:ENSP00000325732 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:5FnCgrz0xltEkgw3yh70KP2jz5g9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O43684 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1050987|uniprotkb:O43685|uniprotkb:B2R6E7|uniprotkb:A6NJ42|uniprotkb:D3DRE9|ensembl:ENSP00000357858 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:bub3_human(display_long)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001007794.1|refseq:NP_004716.1|ensembl:ENSG00000154473(gene)|ensembl:ENST00000368865(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR020472|interpro:IPR036322|mint:O43684|reactome:R-HSA-141430|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|dip:DIP-24205N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:nqzARPql2cThSUpxSb6PuTRn51E9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q12931 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1055869|uniprotkb:O43642|uniprotkb:O75235|uniprotkb:Q9UHL5|uniprotkb:B4DR68|uniprotkb:F5H897|uniprotkb:D3DUC8|ensembl:ENSP00000246957 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:trap1_human(display_long)|uniprotkb:TRAP1(gene name)|psi-mi:TRAP1(display_short)|uniprotkb:HSP75(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_057376.2|refseq:NP_001258978.1|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q12931|rcsb pdb:4Z1F|rcsb pdb:4Z1G|rcsb pdb:4Z1H|rcsb pdb:4Z1I|rcsb pdb:5F3K|rcsb pdb:5F5R|rcsb pdb:5HPH|rcsb pdb:5Y3N|rcsb pdb:5Y3O|rcsb pdb:6XG6|rcsb pdb:7C04|rcsb pdb:7C05|rcsb pdb:7C7B|rcsb pdb:7C7C|reactome:R-HSA-611105|ensembl:ENSG00000126602(gene)|ensembl:ENST00000246957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|dip:DIP-6250N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:O/i+7vgZQcDQF3xJTeqNLbWiQ8U9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P26599 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-350540|ensembl:ENSP00000014112|intact:EBI-744534|uniprotkb:Q9BUQ0 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ptbp1_human(display_long)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:PTB(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein I(gene name synonym)|uniprotkb:57 kDa RNA-binding protein PPTB-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_002810.1|refseq:NP_114367.1|refseq:NP_114368.1|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0016020"(membrane)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034798|interpro:IPR035000|interpro:IPR035001|interpro:IPR035979|mint:P26599|rcsb pdb:1QM9|rcsb pdb:1SJQ|ensembl:ENSG00000011304(gene)|ensembl:ENST00000349038(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|rcsb pdb:2AD9|rcsb pdb:2ADB|rcsb pdb:2ADC|rcsb pdb:2EVZ|rcsb pdb:2N3O|rcsb pdb:3ZZY|rcsb pdb:3ZZZ|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|rcsb pdb:1SJR - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:fkSnYJELgHxDP0oAQEjBmSX0HIs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14315 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P52948 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q1ED39 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-9977982|uniprotkb:O43328|uniprotkb:Q5FWF3|ensembl:ENSP00000219837 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:knop1_human(display_long)|uniprotkb:KNOP1(gene name)|psi-mi:KNOP1(display_short)|uniprotkb:C16orf88(gene name synonym)|uniprotkb:FAM191A(gene name synonym)|uniprotkb:TSG118(gene name synonym)|uniprotkb:Protein FAM191A(gene name synonym)|uniprotkb:Testis-specific gene 118 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001013009.2|refseq:NP_001335457.1|refseq:NP_001335458.1|refseq:NP_001335459.1|refseq:NP_001335460.1|ensembl:ENSG00000103550(gene)|ensembl:ENST00000219837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|interpro:IPR028124 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:DbTowYDo0km0cUlAS8TTL5JIyyQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q92616 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356221|ensembl:ENSP00000300648|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000089154(gene)|ensembl:ENST00000300648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|go:"GO:0005844"(polysome)|refseq:NP_006827.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:NtSEW6xjvCkUyb40cnk0JdL5PcA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P53618 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P33981 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1645856|uniprotkb:Q15272|uniprotkb:Q5TCS0|uniprotkb:Q9BW51|uniprotkb:Q9NTM0|uniprotkb:E1P543|uniprotkb:B2RDW2|uniprotkb:A8K8U5|ensembl:ENSP00000358813 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ttk_human(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)|uniprotkb:MPS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_003309.2|refseq:XP_011534401.1|refseq:XP_011534402.1|refseq:NP_001160163.1|dip:DIP-40642N|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903096"(protein localization to meiotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|rcsb pdb:2X9E|rcsb pdb:2ZMC|rcsb pdb:2ZMD|rcsb pdb:3CEK|rcsb pdb:3DBQ|rcsb pdb:3GFW|rcsb pdb:3H9F|rcsb pdb:3HMN|rcsb pdb:3HMO|rcsb pdb:3HMP|rcsb pdb:3VQU|rcsb pdb:3W1F|rcsb pdb:3WYX|rcsb pdb:3WYY|rcsb pdb:3WZK|rcsb pdb:4B94|rcsb pdb:4BHZ|rcsb pdb:4BI0|rcsb pdb:4BI1|rcsb pdb:4BI2|rcsb pdb:4C4E|rcsb pdb:4C4F|rcsb pdb:4C4G|rcsb pdb:4C4H|rcsb pdb:4C4I|rcsb pdb:4C4J|rcsb pdb:4CV8|rcsb pdb:4CV9|rcsb pdb:4CVA|rcsb pdb:4D2S|rcsb pdb:4H7X|rcsb pdb:4H7Y|rcsb pdb:4JS8|rcsb pdb:4JT3|rcsb pdb:4O6L|rcsb pdb:4ZEG|rcsb pdb:5AP0|rcsb pdb:5AP1|rcsb pdb:5AP2|rcsb pdb:5AP3|rcsb pdb:5AP4|rcsb pdb:5AP5|rcsb pdb:5AP6|rcsb pdb:5AP7|rcsb pdb:5EH0|rcsb pdb:5EHL|rcsb pdb:5EHO|rcsb pdb:5EHY|rcsb pdb:5EI2|rcsb pdb:5EI6|rcsb pdb:5EI8|rcsb pdb:5LJJ|rcsb pdb:5MRB|rcsb pdb:5N7V|rcsb pdb:5N84|rcsb pdb:5N87|rcsb pdb:5N93|rcsb pdb:5N9S|rcsb pdb:5NA0|rcsb pdb:5NAD|rcsb pdb:5NTT|rcsb pdb:5O91|rcsb pdb:6B4W|rcsb pdb:6GVJ|rcsb pdb:6H3K|rcsb pdb:6N6O|rcsb pdb:6TN9|rcsb pdb:6TNB|rcsb pdb:6TNC|rcsb pdb:6TND|rcsb pdb:7CHM|rcsb pdb:7CHN|rcsb pdb:7CHT|rcsb pdb:7CIL|rcsb pdb:7CJA|rcsb pdb:7CLH|rcsb pdb:3WZJ - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q12894 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2512448|ensembl:ENSP00000402849|intact:EBI-6115935|uniprotkb:Q9BVB4|uniprotkb:Q9UJ88 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ifrd2_human(display_long)|uniprotkb:Protein SKMC15(gene name synonym)|uniprotkb:IFRD2(gene name)|psi-mi:IFRD2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000214706(gene)|ensembl:ENST00000417626(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR006921(Interferon-related protein conserved region)|interpro:IPR007701(Interferon-related developmental regulator)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039777|refseq:NP_006755.4 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:ktxpbUgNcw2DWOJw8o1R4s+U3a09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q09028 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O43818 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2115327|uniprotkb:Q8IZ30|uniprotkb:B2R996|ensembl:ENSP00000232888 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:u3ip2_human(display_long)|uniprotkb:RRP9(gene name)|psi-mi:RRP9(display_short)|uniprotkb:RNU3IP2(gene name synonym)|uniprotkb:U355K(gene name synonym)|uniprotkb:U3 small nucleolar ribonucleoprotein-associated 55 kDa protein(gene name synonym)|uniprotkb:RRP9 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004695.1|ensembl:ENSG00000114767(gene)|ensembl:ENST00000232888(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR039241|rcsb pdb:4J0W|rcsb pdb:4JXM|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:AxnPDovGXO2JPghV7c6ztiV1/z89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14980 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O15260 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62244 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-347895|ensembl:ENSP00000318646|ensembl:ENSP00000457000|ensembl:ENSP00000458115|ensembl:ENSP00000458528|uniprotkb:P39027|uniprotkb:P39031|uniprotkb:Q3MHD9|uniprotkb:Q8C023|uniprotkb:Q9BV24 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs15a_human(display_long)|uniprotkb:RPS15A(gene name)|psi-mi:RPS15A(display_short)|uniprotkb:Small ribosomal subunit protein uS8(gene name synonym)|uniprotkb:OK/SW-cl.82(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000134419(gene)|ensembl:ENST00000322989(transcript)|ensembl:ENST00000563390(transcript)|ensembl:ENST00000565420(transcript)|ensembl:ENST00000572008(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045787"(positive regulation of cell cycle)|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|go:"GO:0070062"(extracellular exosome)|rcsb pdb:6G4W|interpro:IPR000630(Ribosomal protein S8)|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|interpro:IPR035987|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|mint:P62244|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:4V6X|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-72695|reactome:R-HSA-975957|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZM7|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|refseq:NP_001010.2|refseq:NP_001025180.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Qdnhk7yvoFFYcRq5kEi7GQILaxs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P35232 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96EV2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1210748|uniprotkb:B5MC24|uniprotkb:A4D244|uniprotkb:Q52LF5|uniprotkb:Q75LN9|uniprotkb:Q75ML5|uniprotkb:Q9NSV0|ensembl:ENSP00000384160 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rbm33_human(display_long)|uniprotkb:RBM33(gene name)|psi-mi:RBM33(display_short)|uniprotkb:PRR8(gene name synonym)|uniprotkb:RNA-binding motif protein 33(gene name synonym)|uniprotkb:Proline-rich protein 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_444271.2|ensembl:ENST00000287912|ensembl:ENSP00000287912|ensembl:ENSP00000384160|ensembl:ENSG00000184863(gene)|ensembl:ENST00000401878(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR039878 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:b+J1rpxK+YeVvWBkCUPaaQBdCUo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P25398 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354542|uniprotkb:Q76M58|ensembl:ENSP00000230050 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs12_human(display_long)|uniprotkb:RPS12(gene name)|psi-mi:RPS12(display_short)|uniprotkb:Small ribosomal subunit protein eS12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001007.2|ensembl:ENSG00000112306(gene)|ensembl:ENST00000230050(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000530(Ribosomal protein S12e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72702|reactome:R-HSA-72695|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:80AIouzSdCvnLUSA7qsMp6naZ3g9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P11142 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y285 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-725361|uniprotkb:Q9NSD8|uniprotkb:Q9Y4W8|uniprotkb:B4E363|ensembl:ENSP00000320309 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:syfa_human(display_long)|uniprotkb:CML33(gene name synonym)|uniprotkb:FARSA(gene name)|psi-mi:FARSA(display_short)|uniprotkb:FARS(gene name synonym)|uniprotkb:FARSLA(gene name synonym)|uniprotkb:FARSL(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004452.1|ensembl:ENSG00000179115(gene)|ensembl:ENST00000314606(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|mint:Q9Y285|rcsb pdb:3L4G|reactome:R-HSA-379716|dip:DIP-53610N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:FpOCk4Mzmsb2CnIUwUKg5nRg7/U9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9HCS7 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-295232|uniprotkb:Q8TET6|uniprotkb:Q96HB0|uniprotkb:Q96IW0|uniprotkb:Q9NRG6|uniprotkb:Q9ULP3|ensembl:ENSP00000351137 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:syf1_human(display_long)|uniprotkb:XAB2(gene name)|psi-mi:XAB2(display_short)|uniprotkb:HCNP(gene name synonym)|uniprotkb:KIAA1177(gene name synonym)|uniprotkb:PP3898(orf name)|uniprotkb:SYF1(gene name synonym)|uniprotkb:XPA-binding protein 2(gene name synonym)|uniprotkb:Protein HCNP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_064581.2|dip:DIP-31646N|ensembl:ENSG00000076924(gene)|ensembl:ENST00000358368(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9HCS7|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:6+Vu8QmYaVK/kd5ADY6uaUY35SQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9P258 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352547|uniprotkb:Q8IVL9|uniprotkb:Q9BSN6|uniprotkb:Q9NPV8|ensembl:ENSP00000364582|ensembl:ENSP00000364585|ensembl:ENSP00000486099|ensembl:ENSP00000486447 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rcc2_human(display_long)|uniprotkb:RCC2(gene name)|psi-mi:RCC2(display_short)|uniprotkb:KIAA1470(gene name synonym)|uniprotkb:TD60(gene name synonym)|uniprotkb:Telophase disk protein of 60 kDa(gene name synonym)|uniprotkb:RCC1-like protein TD-60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001129676.1|refseq:NP_061185.1|ensembl:ENSG00000179051(gene)|ensembl:ENSG00000281540(gene)|ensembl:ENST00000375433(transcript)|ensembl:ENST00000375436(transcript)|ensembl:ENST00000628984(transcript)|ensembl:ENST00000631021(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051301"(cell division)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072356"(chromosome passenger complex localization to kinetochore)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR028641|mint:Q9P258|rcsb pdb:5GWN|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:z9+0avftBLs4Q3ODFHLEmJtd57A9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UMS4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-395746|ensembl:ENSP00000227524 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:prp19_human(display_long)|uniprotkb:PRPF19(gene name)|psi-mi:PRPF19(display_short)|uniprotkb:PRP19/PSO4 homolog(gene name synonym)|uniprotkb:Nuclear matrix protein 200(gene name synonym)|uniprotkb:Senescence evasion factor(gene name synonym)|uniprotkb:NMP200(gene name synonym)|uniprotkb:PRP19(gene name synonym)|uniprotkb:SNEV(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000110107(gene)|ensembl:ENST00000227524(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005819"(spindle)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_055317.1|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR038959|mint:Q9UMS4|rcsb pdb:4LG8|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|dip:DIP-32978N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:5TseaFcCOVVWjJeMF/H7k29nd3c9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NP77 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2515416|ensembl:ENSP00000291386|uniprotkb:Q9H933|uniprotkb:Q9BZS6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ssu72_human(display_long)|uniprotkb:SSU72(gene name)|psi-mi:SSU72(display_short)|uniprotkb:HSPC182(orf name)|uniprotkb:PNAS-120(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000160075(gene)|ensembl:ENST00000291386(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR006811(Ssu72-like protein)|rcsb pdb:3O2Q|rcsb pdb:3O2S|rcsb pdb:4H3H|rcsb pdb:4H3K|reactome:R-HSA-6807505|refseq:NP_054907.1|dip:DIP-53666N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:v/C7oHkhi8bmjogExGZj/QI3TO49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:A8K8V0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-3925400|ensembl:ENSP00000378642|uniprotkb:Q96MN0|uniprotkb:O75701|uniprotkb:Q8WV14|uniprotkb:Q8IW91 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:zn785_human(display_long)|uniprotkb:ZNF785(gene name)|psi-mi:ZNF785(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000197162(gene)|ensembl:ENST00000395216(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_689671.2|refseq:XP_016878456.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:uuRdGybcIfhEq2V5VH2retk/p3I9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y2L1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-373539|uniprotkb:A6NI21|uniprotkb:Q5W0P7|uniprotkb:Q5W0P8|uniprotkb:Q658Z7|uniprotkb:Q7Z481|uniprotkb:Q8WWI2|uniprotkb:Q9UG36|uniprotkb:B2RBL2|ensembl:ENSP00000366997 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rrp44_human(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Protein DIS3 homolog(gene name synonym)|uniprotkb:KIAA1008(gene name synonym)|uniprotkb:RRP44(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001121698.1|refseq:NP_055768.3|ensembl:ENSG00000083520(gene)|ensembl:ENST00000377767(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|mint:Q9Y2L1|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:cHOcZh1JkvywNK4Tq2DUvPMm6kc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UKA9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-954220|ensembl:ENSP00000502818|uniprotkb:Q8N0Z1|uniprotkb:Q8N160|uniprotkb:Q8NFB0|uniprotkb:Q8NFB1|uniprotkb:Q969N9|uniprotkb:Q96Q76 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ptbp2_human(display_long)|uniprotkb:Neurally-enriched homolog of PTB(gene name synonym)|uniprotkb:Neural polypyrimidine tract-binding protein(gene name synonym)|uniprotkb:PTB-like protein(gene name synonym)|uniprotkb:PTBP2(gene name)|psi-mi:PTBP2(display_short)|uniprotkb:NPTB(gene name synonym)|uniprotkb:PTB(gene name synonym)|uniprotkb:PTBLP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 rcsb pdb:2MJU|rcsb pdb:4CQ1|ensembl:ENSG00000117569(gene)|ensembl:ENST00000674951(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034798|interpro:IPR034799|interpro:IPR034800|interpro:IPR035002|interpro:IPR035979|mint:Q9UKA9|rcsb pdb:2CQ1|refseq:NP_067013.1|refseq:NP_001287914.1|refseq:NP_001287915.1|refseq:NP_001287916.1|refseq:NP_001287917.1|refseq:NP_001287918.1|refseq:NP_001287919.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:HRWj6xZbfhYShcsdMR97O7CD4/Y9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H501 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2681618|uniprotkb:Q9H9Q5|uniprotkb:Q86X92|uniprotkb:Q9P1S6|uniprotkb:Q9NX93|uniprotkb:Q9HA35|ensembl:ENSP00000202816|ensembl:ENSP00000480783 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:esf1_human(display_long)|uniprotkb:ABTAP(gene name synonym)|uniprotkb:C20orf6(gene name synonym)|uniprotkb:ABT1-associated protein(gene name synonym)|uniprotkb:HDCMC28P(orf name)|uniprotkb:ESF1(gene name)|psi-mi:ESF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_057733.2|refseq:NP_001263309.1|ensembl:ENSG00000089048(gene)|ensembl:ENST00000202816(transcript)|ensembl:ENST00000617257(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|interpro:IPR012580(NUC153)|interpro:IPR039754|refseq:XP_016883363.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:krVdiYCRbuBlZADkOv9/vNcCX+s9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15654 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q13148 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-372899|uniprotkb:Q6FI92|uniprotkb:E2PU12|uniprotkb:Q96DJ0|intact:EBI-2821405|uniprotkb:A4GUK4|uniprotkb:A4GUK5|uniprotkb:A4GUK6|uniprotkb:B2R629|uniprotkb:Q53H27|uniprotkb:B4DJ45|ensembl:ENSP00000240185|ensembl:ENSP00000491203 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tadbp_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short)|uniprotkb:TDP43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_031401.1|ensembl:ENSG00000120948(gene)|ensembl:ENST00000240185(transcript)|ensembl:ENST00000639083(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q13148|rcsb pdb:1WF0|rcsb pdb:2CQG|rcsb pdb:2N2C|rcsb pdb:2N3X|rcsb pdb:2N4G|rcsb pdb:2N4H|rcsb pdb:2N4P|rcsb pdb:4BS2|rcsb pdb:4IUF|rcsb pdb:4Y00|rcsb pdb:4Y0F|rcsb pdb:5MDI|rcsb pdb:5MRG|rcsb pdb:5W50|rcsb pdb:5W52|rcsb pdb:5W7V|rcsb pdb:5WHN|rcsb pdb:5WHP|rcsb pdb:5WIA|rcsb pdb:5WIQ|rcsb pdb:5WKB|rcsb pdb:5WKD|rcsb pdb:5X4F|rcsb pdb:6B1G|rcsb pdb:6CF4|rcsb pdb:6CFH|rcsb pdb:6N37|rcsb pdb:6N3A|rcsb pdb:6N3B|rcsb pdb:6N3C|rcsb pdb:6T4B|rcsb pdb:7KWZ|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031647"(regulation of protein stability)|refseq:XP_016856352.1|refseq:XP_016856353.1|refseq:XP_016856354.1|refseq:XP_016856355.1|refseq:XP_016856356.1|refseq:XP_016856357.1|dip:DIP-31167N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:KG5C6KnWiKeFQLYbHcfr9a11Ro49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P52294 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-358383|uniprotkb:Q9BQ56|uniprotkb:Q6IBQ9|intact:EBI-1058734|ensembl:ENSP00000343701|uniprotkb:D3DN93 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ima5_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short)|uniprotkb:RCH2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_002255.3|ensembl:ENSG00000114030(gene)|ensembl:ENST00000344337(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52294|rcsb pdb:2JDQ|rcsb pdb:3TJ3|rcsb pdb:4B18|rcsb pdb:6WX9|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-162592|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180910|reactome:R-HSA-909733|reactome:R-HSA-9636249|dip:DIP-29296N|refseq:XP_005247494.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:eha8sOMYqe0OC6eXBA4eJLLsKFs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P31943 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P27708 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UKV3 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-396258|uniprotkb:O75158|uniprotkb:Q9UG91|uniprotkb:Q9UKV1|uniprotkb:Q9UKV2|uniprotkb:D3DS45|uniprotkb:B2RTT4|ensembl:ENSP00000262710 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:acinu_human(display_long)|uniprotkb:ACIN1(gene name)|psi-mi:ACIN1(display_short)|uniprotkb:ACINUS(gene name synonym)|uniprotkb:KIAA0670(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001158286.1|refseq:NP_001158287.1|refseq:NP_001158288.1|refseq:NP_001158289.1|refseq:NP_055792.1|refseq:XP_005267475.1|ensembl:ENSG00000100813(gene)|ensembl:ENST00000262710(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034257|interpro:IPR035979|interpro:IPR036361|mint:Q9UKV3|rcsb pdb:6G6S|reactome:R-HSA-111465|interpro:IPR032552|dip:DIP-32963N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:dzHCIefdTYTGEk+qXNwlK2Phybw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14974 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P33992 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-359410|ensembl:ENSP00000216122|uniprotkb:O60785|uniprotkb:Q14578|uniprotkb:Q9BTJ4|uniprotkb:Q9BWL8 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mcm5_human(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:CDC46 homolog(gene name synonym)|uniprotkb:P1-CDC46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000100297(gene)|ensembl:ENST00000216122(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33992|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_006730.2|reactome:R-HSA-69052|reactome:R-HSA-68962|dip:DIP-27578N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:WjJ4lSpADQFtwT0WnumbRHl/lPw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O00571 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15365 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P42677 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UK58 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2836773|uniprotkb:B3KMY3|uniprotkb:Q96QT0|uniprotkb:Q9NZF3|uniprotkb:Q8NI48|uniprotkb:Q6NVY9|uniprotkb:Q6UWS7|intact:EBI-11158173|uniprotkb:C9JPL0|ensembl:ENSP00000295926 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ccnl1_human(display_long)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_064703.1|refseq:NP_001295114.1|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015431(Cyclin L, metazoan)|interpro:IPR036915|interpro:IPR043198|mint:Q9UK58|refseq:XP_016862381.1|refseq:XP_016862382.1|refseq:XP_016862383.1|refseq:XP_016862384.1|refseq:XP_016862385.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NVI7 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352007|ensembl:ENSP00000368030|uniprotkb:Q5SV23|uniprotkb:Q8N275|uniprotkb:Q96A50|uniprotkb:B3KPB3|uniprotkb:D2K8Q1|uniprotkb:G3V1I6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:atd3a_human(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001164006.1|refseq:NP_001164007.1|refseq:NP_060658.3|ensembl:ENSG00000197785(gene)|ensembl:ENST00000378755(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q9NVI7|dip:DIP-33194N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:IZKJEVLLS/DFINgBgO5frizN1P49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8IY37 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-308285|uniprotkb:Q9BUI7|uniprotkb:Q9P211|ensembl:ENSP00000311135 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:dhx37_human(display_long)|uniprotkb:DHX37(gene name)|psi-mi:DHX37(display_short)|uniprotkb:DDX37(gene name synonym)|uniprotkb:KIAA1517(gene name synonym)|uniprotkb:DEAH box protein 37(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_116045.2|ensembl:ENSG00000150990(gene)|ensembl:ENST00000308736(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007420"(brain development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042255"(ribosome assembly)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000020"(positive regulation of male gonad development)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q8IY37|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:y+2TFmurlGgCJ2pjTjfAttqC3xE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15029 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-357897|uniprotkb:Q9BUR0|uniprotkb:D3DX58|uniprotkb:B4DK30|ensembl:ENSP00000392094|ensembl:ENSP00000467805|uniprotkb:B4DMC0|uniprotkb:K7EJ81 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:u5s1_human(display_long)|uniprotkb:EFTUD2(gene name)|psi-mi:EFTUD2(display_short)|uniprotkb:KIAA0031(gene name synonym)|uniprotkb:SNRP116(gene name synonym)|uniprotkb:U5 snRNP-specific protein, 116 kDa(gene name synonym)|uniprotkb:Elongation factor Tu GTP-binding domain-containing protein 2(gene name synonym)|uniprotkb:SNU114 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001136077.1|refseq:NP_004238.3|refseq:NP_001245282.1|go:"GO:0042220"(response to cocaine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR041095|interpro:IPR044121|mint:Q15029|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|go:"GO:0035690"|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000108883(gene)|ensembl:ENST00000426333(transcript)|ensembl:ENST00000591382(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030623"(U5 snRNA binding)|refseq:NP_001245283.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:/dBQ7TFnGr31AYrb5e215eQ4vfc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O75676 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-73933|uniprotkb:O75585|uniprotkb:Q53ES8|uniprotkb:A8K7Z8|ensembl:ENSP00000333896 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ks6a4_human(display_long)|uniprotkb:Nuclear mitogen- and stress-activated protein kinase 2(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 4(gene name synonym)|uniprotkb:Ribosomal protein kinase B(gene name synonym)|uniprotkb:RPS6KA4(gene name)|psi-mi:RPS6KA4(display_short)|uniprotkb:MSK2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001006945.1|refseq:NP_003933.1|refseq:NP_001305290.1|refseq:NP_001287731.1|ensembl:ENSG00000162302(gene)|ensembl:ENST00000334205(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043987"(histone H3-S10 phosphorylation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR037714|mint:O75676|reactome:R-HSA-437239 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:C2Zpzuq3c99BNpYuJBozPWc/1DA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P38919 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-299104|ensembl:ENSP00000497641|ensembl:ENSP00000497661|uniprotkb:Q15033|uniprotkb:Q96A18|uniprotkb:Q6IBQ2 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:if4a3_human(display_long)|uniprotkb:KIAA0111(gene name synonym)|uniprotkb:EIF4A3(gene name)|psi-mi:EIF4A3(display_short)|uniprotkb:DDX48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym)|uniprotkb:Eukaryotic initiation factor 4A-like NUK-34(gene name synonym)|uniprotkb:Nuclear matrix protein 265(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008306"(associative learning)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072715"(cellular response to selenite ion)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P38919|rcsb pdb:2HXY|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2J0U|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:4C9B|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6YVH|rcsb pdb:7A5P|reactome:R-HSA-1169408|reactome:R-HSA-159236|reactome:R-HSA-429947|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENST00000647795(transcript)|ensembl:ENST00000649764(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|ensembl:ENSG00000141543(gene)|refseq:NP_055555.1|dip:DIP-33218N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:8e6e4HlM1GsYqqgXyJ9XgzxLzls9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NVA2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-957999|uniprotkb:Q7L4N1|uniprotkb:Q96SP1|uniprotkb:B7Z7Z6|uniprotkb:Q4W5G1|uniprotkb:Q9UFY9|ensembl:ENSP00000264893|uniprotkb:E9KL32 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:sep11_human(display_long)|uniprotkb:SEPTIN11(gene name)|psi-mi:SEPTIN11(display_short)|uniprotkb:SEPT11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060713.1|ensembl:ENSG00000138758(gene)|ensembl:ENST00000264893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099629"(postsynaptic specialization of symmetric synapse)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6UPQ|refseq:NP_001293076.1|refseq:XP_016863889.1|dip:DIP-36161N - - crc64:D467F1F315FFD028 figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:2dJm0WBfPs71hp1nBoMeGF/DR2s9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q00839 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O75494 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-353655|uniprotkb:Q5JRI3|uniprotkb:Q5JRI4|uniprotkb:A6NFM6|uniprotkb:A6NI42|uniprotkb:A6NIU7|uniprotkb:Q5JRH9|uniprotkb:Q5JRI2|uniprotkb:O60572|uniprotkb:Q96G09|uniprotkb:Q96P17|uniprotkb:Q5JRI0|intact:EBI-11103259|ensembl:ENSP00000420195|uniprotkb:B4DJP9 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:srs10_human(display_long)|uniprotkb:FUSIP1(gene name synonym)|uniprotkb:TASR(gene name synonym)|uniprotkb:FUS-interacting serine-arginine-rich protein 1(gene name synonym)|uniprotkb:FUSIP2(gene name synonym)|uniprotkb:TLS-associated protein with Ser-Arg repeats(gene name synonym)|uniprotkb:TLS-associated serine-arginine protein(gene name synonym)|uniprotkb:40 kDa SR-repressor protein(gene name synonym)|uniprotkb:SRSF10(gene name)|psi-mi:SRSF10(display_short)|uniprotkb:Splicing factor SRp38(gene name synonym)|uniprotkb:SFRS13A(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 13A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001177936.1|refseq:NP_001177934.1|refseq:NP_001177935.1|refseq:NP_006616.1|refseq:NP_473357.1|ensembl:ENSG00000188529(gene)|ensembl:ENST00000492112(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016482"(cytosolic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034476|interpro:IPR035979|mint:O75494|reactome:R-HSA-72163|refseq:NP_001177938.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:abrRZLYWl3wlG2rHzVZMgej5EWk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NZM5 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_056525.2|ensembl:ENSG00000105373(gene)|ensembl:ENST00000246802(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0003723"(RNA binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990173"(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|go:"GO:0050821"(protein stabilization) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UJX3 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1384164|uniprotkb:Q96AC4|uniprotkb:Q96GF4|uniprotkb:Q9BU24|uniprotkb:Q9NT16|ensembl:ENSP00000394394|ensembl:ENSP00000402314 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:apc7_human(display_long)|uniprotkb:ANAPC7(gene name)|psi-mi:ANAPC7(display_short)|uniprotkb:APC7(gene name synonym)|uniprotkb:Cyclosome subunit 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001131136.1|refseq:NP_057322.2|dip:DIP-39765N|ensembl:ENSG00000196510(gene)|ensembl:ENST00000450008(transcript)|ensembl:ENST00000455511(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX3|rcsb pdb:3FFL|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:2q+llvuIzK2MOWjPuOUxmyN782E9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q12788 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-715766|uniprotkb:Q59GD6|uniprotkb:Q8IVB7|intact:EBI-749106|uniprotkb:Q96A78|ensembl:ENSP00000454836 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tbl3_human(display_long)|uniprotkb:WD repeat-containing protein SAZD(gene name synonym)|uniprotkb:TBL3(gene name)|psi-mi:TBL3(display_short)|uniprotkb:SAZD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006444.2|ensembl:ENSG00000183751(gene)|ensembl:ENST00000568546(transcript)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013934(Small-subunit processome, Utp13)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q12788|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:XFWYZxef3kNBYeTaoSBWEXQoF/M9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P42766 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356819|uniprotkb:Q4VBY5|uniprotkb:Q9BYF4|uniprotkb:Q5JTN5|uniprotkb:Q6IBC7|uniprotkb:Q96QJ7|uniprotkb:A8K4V7|ensembl:ENSP00000259469 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl35_human(display_long)|uniprotkb:RPL35(gene name)|psi-mi:RPL35(display_short)|uniprotkb:Large ribosomal subunit protein uL29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_009140.1|ensembl:ENSG00000136942(gene)|ensembl:ENST00000348462(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|mint:P42766|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:jhzt7gCff2vdUb1Ff/VTBF698Pg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P52907 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O95625 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-5564743|uniprotkb:Q2NKP9|ensembl:ENSP00000326200 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:zbt11_human(display_long)|uniprotkb:ZBTB11(gene name)|psi-mi:ZBTB11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055230.2|ensembl:ENSG00000066422(gene)|ensembl:ENST00000312938(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041588 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:C9bIyaJIch3I4cCHPHy7vOJZEYI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P08107 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:NFv4uj12xAWIr+OltarRlLDPr949606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H8H0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-725885|uniprotkb:Q7L5S1|uniprotkb:Q9UG18|uniprotkb:B7Z5V9|ensembl:ENSP00000253247 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nol11_human(display_long)|uniprotkb:NOL11(gene name)|psi-mi:NOL11(display_short)|uniprotkb:L14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_056277.2|refseq:NP_001290201.1|ensembl:ENSG00000130935(gene)|ensembl:ENST00000253247(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0034455"(t-UTP complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR012584(NUC205)|interpro:IPR036322|interpro:IPR042859|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:DerJ7iPKNSsk7il8nQJQUQn6uCw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O75691 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356062|uniprotkb:Q9H3H4|ensembl:ENSP00000261637 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:utp20_human(display_long)|uniprotkb:UTP20(gene name)|psi-mi:UTP20(display_short)|uniprotkb:DRIM(gene name synonym)|uniprotkb:Down-regulated in metastasis protein(gene name synonym)|uniprotkb:Protein Key-1A6(gene name synonym)|uniprotkb:Novel nucleolar protein 73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055318.2|ensembl:ENSG00000120800(gene)|ensembl:ENST00000261637(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|interpro:IPR011430(Down-regulated in metastasis)|interpro:IPR016024(Armadillo-type fold)|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:OxTEfw2MtOijthWHjRtqIqUUjjg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P25205 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y5Q9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1054873|uniprotkb:Q4ZG48|uniprotkb:Q86XJ8|uniprotkb:Q8WX84|uniprotkb:Q96B44|uniprotkb:Q9H5I8|uniprotkb:Q9NT97|intact:EBI-1237212|ensembl:ENSP00000263956 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tf3c3_human(display_long)|uniprotkb:GTF3C3(gene name)|psi-mi:GTF3C3(display_short)|uniprotkb:Transcription factor IIIC subunit gamma(gene name synonym)|uniprotkb:Transcription factor IIIC 102 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001193703.1|refseq:NP_036218.1|ensembl:ENSG00000119041(gene)|ensembl:ENST00000263956(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039340|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:cF53nd62xSXQfZerd7bdfB2KUgk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BVI4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-395927|uniprotkb:Q8N2S5|uniprotkb:Q96I14|ensembl:ENSP00000328854|ensembl:ENSP00000500901 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:noc4l_human(display_long)|uniprotkb:NOC4-like protein(gene name synonym)|uniprotkb:Nucleolar complex-associated protein 4-like protein(gene name synonym)|uniprotkb:NOC4L(gene name)|psi-mi:NOC4L(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_076983.1|ensembl:ENSG00000184967(gene)|ensembl:ENSG00000288146(gene)|ensembl:ENST00000330579(transcript)|ensembl:ENST00000672504(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030692"(Noc4p-Nop14p complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032040"(small-subunit processome)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027193|mint:Q9BVI4|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-32938N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:PczuDyeVf4oAGktQfOSfHWmrCwA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O00422 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1044156|uniprotkb:Q2TTR4|uniprotkb:Q6IAW9|uniprotkb:Q8N606|uniprotkb:Q9UF14|ensembl:ENSP00000475925|uniprotkb:B2R494|uniprotkb:X6RAL5 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:sap18_human(display_long)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 38 protein(gene name synonym)|uniprotkb:2HOR0202(gene name synonym)|uniprotkb:SAP18(gene name)|psi-mi:SAP18(display_short)|uniprotkb:GIG38(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000150459(gene)|ensembl:ENST00000607003(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O00422|rcsb pdb:2HDE|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|refseq:NP_005861.2|dip:DIP-33590N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:eJoksFCc7vBoAjJEpnXJvc/yg+Q9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q13309 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-456291|uniprotkb:Q8TDZ0|uniprotkb:Q8TDZ1|uniprotkb:Q9BV69|ensembl:ENSP00000274255|uniprotkb:A8K5E0|uniprotkb:B4DJT4 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:skp2_human(display_long)|uniprotkb:F-box protein Skp2(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p45(gene name synonym)|uniprotkb:p45skp2(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 1(gene name synonym)|uniprotkb:SKP2(gene name)|psi-mi:SKP2(display_short)|uniprotkb:FBXL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000145604(gene)|ensembl:ENST00000274255(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|rcsb pdb:2ASS|rcsb pdb:2AST|interpro:IPR032675|rcsb pdb:7B5L|interpro:IPR036047|mint:Q13309|rcsb pdb:1FQV|rcsb pdb:7B5M|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|refseq:NP_005974.2|refseq:NP_116026.1|refseq:NP_001230049.1|dip:DIP-17011N|rcsb pdb:7B5R|reactome:R-HSA-174178|reactome:R-HSA-187577|reactome:R-HSA-5689880|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9687136|reactome:R-HSA-9708530|reactome:R-HSA-983168 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:VABxcX3qu0Yr6eRNYINqvAPhPMc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q13263 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q66LE6 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q5T3I0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2372076|uniprotkb:Q5T3I1|uniprotkb:Q6ZUE7|uniprotkb:Q8IWG8|uniprotkb:Q9NXH4 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:gptc4_human(display_long)|uniprotkb:GPATCH4(gene name)|psi-mi:GPATCH4(display_short)|uniprotkb:GPATC4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 interpro:IPR000467(D111/G-patch)|mint:Q5T3I0|go:"GO:0003723"(RNA binding) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:R2hFHYGQh2jmLbLg+BNATVimtNA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O75643 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1045395|uniprotkb:O94884|uniprotkb:Q6PX59|uniprotkb:Q8NBE6|uniprotkb:Q96IF2|uniprotkb:Q9H7S0|uniprotkb:Q6NZY0|intact:EBI-1051631|ensembl:ENSP00000317123 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:u520_human(display_long)|uniprotkb:SNRNP200(gene name)|psi-mi:SNRNP200(display_short)|uniprotkb:HELIC2(gene name synonym)|uniprotkb:KIAA0788(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym)|uniprotkb:Activating signal cointegrator 1 complex subunit 3-like 1(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:ASCC3L1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_054733.2|ensembl:ENSG00000144028(gene)|ensembl:ENST00000323853(transcript)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|mint:O75643|rcsb pdb:2Q0Z|rcsb pdb:3JCR|rcsb pdb:4F91|rcsb pdb:4F92|rcsb pdb:4F93|rcsb pdb:4KIT|rcsb pdb:5O9Z|rcsb pdb:5URJ|rcsb pdb:5URK|rcsb pdb:5URM|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8O|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:XP_016859092.1|dip:DIP-31659N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:2ZAcbMfMlk2xWWAiy7MeCL0CHtM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P21127 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1298|uniprotkb:O95265|uniprotkb:Q12817|uniprotkb:Q12818|uniprotkb:Q12819|uniprotkb:Q12820|uniprotkb:Q12822|uniprotkb:Q8N530|uniprotkb:Q9NZS5|uniprotkb:Q9UBJ0|uniprotkb:Q9UBQ1|uniprotkb:Q9UBR0|uniprotkb:Q9UNY2|uniprotkb:Q9UP57|uniprotkb:Q9UP58|uniprotkb:Q9UP59|uniprotkb:B7ZVY7|uniprotkb:J3KTL7|uniprotkb:J3QR29|uniprotkb:J3QR44|ensembl:ENSP00000464036 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cd11b_human(display_long)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L1(gene name synonym)|uniprotkb:PITSLREA(gene name synonym)|uniprotkb:PK58(gene name synonym)|uniprotkb:CDK11B(gene name)|psi-mi:CDK11B(display_short)|uniprotkb:Cell division cycle 2-like protein kinase 1(gene name synonym)|uniprotkb:p58 CLK-1(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:CDK11(gene name synonym)|uniprotkb:CDC2L1(gene name synonym)|uniprotkb:Cell division protein kinase 11B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_277022.1|refseq:NP_001278274.1|refseq:NP_001778.2|refseq:NP_277021.2|refseq:NP_277024.2|refseq:XP_016858415.1|refseq:NP_277025.1|ensembl:ENSG00000248333(gene)|ensembl:ENST00000407249(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P21127|reactome:R-HSA-380270 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:mwf9SNcd9/lgwTr3OHPqwv/gqV49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q12769 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-295715|uniprotkb:Q96GB3|uniprotkb:Q9H660|uniprotkb:B4DYE8|uniprotkb:B4E2J9|uniprotkb:Q08AD3|uniprotkb:Q7Z5X6|intact:EBI-2563140|ensembl:ENSP00000367721 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nu160_human(display_long)|uniprotkb:NUP160(gene name)|psi-mi:NUP160(display_short)|uniprotkb:KIAA0197(gene name synonym)|uniprotkb:NUP120(gene name synonym)|uniprotkb:Nucleoporin Nup160(gene name synonym)|uniprotkb:160 kDa nucleoporin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_056046.1|refseq:NP_001305328.1|dip:DIP-31262N|ensembl:ENSG00000030066(gene)|ensembl:ENST00000378460(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0072006"(nephron development)|interpro:IPR021717|mint:Q12769|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:15tRpv4+wvw31oJPxM42NxWdRUc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62266 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-353072|ensembl:ENSP00000296674|ensembl:ENSP00000498621|uniprotkb:P39028|uniprotkb:Q6IB08 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs23_human(display_long)|uniprotkb:RPS23(gene name)|psi-mi:RPS23(display_short)|uniprotkb:Small ribosomal subunit protein uS12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000186468(gene)|ensembl:ENST00000296674(transcript)|ensembl:ENST00000651545(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR005680(Ribosomal protein S23, eukaryotic/archaeal)|interpro:IPR006032(Ribosomal protein S12/S23)|rcsb pdb:5T2C|rcsb pdb:5VYC|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|mint:P62266|rcsb pdb:6G4W|rcsb pdb:4CXG|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:4CXH|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:4UG0|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|refseq:NP_001016.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:MWZPvSL/G45ocaxA5AXKCkDQxNU9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O60264 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352588|ensembl:ENSP00000283131 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:smca5_human(display_long)|uniprotkb:SMARCA5(gene name)|psi-mi:SMARCA5(display_short)|uniprotkb:SNF2H(gene name synonym)|uniprotkb:WCRF135(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENST00000283131(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:O60264|rcsb pdb:6NE3|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5693565|reactome:R-HSA-606279|refseq:NP_003592.3|ensembl:ENSG00000153147(gene)|dip:DIP-33204N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:XlXL5MRhAFlqHhGroPdm01lYEk89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P46013 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-876367|uniprotkb:Q5VWH2|ensembl:ENSP00000357643 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ki67_human(display_long)|uniprotkb:MKI67(gene name)|psi-mi:MKI67(display_short)|uniprotkb:Antigen identified by monoclonal antibody Ki-67(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001139438.1|refseq:NP_002408.3|dip:DIP-28132N|ensembl:ENSG00000148773(gene)|ensembl:ENST00000368654(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012568(K167R)|interpro:IPR029334|mint:P46013|rcsb pdb:1R21|rcsb pdb:2AFF|rcsb pdb:5J28 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:kyrLLOv4HSqah1Y6HtzebG978Kw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P78316 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-5454840|uniprotkb:D3DVR6|uniprotkb:Q7LGI5|uniprotkb:Q7Z6K0|uniprotkb:Q8TBR6|ensembl:ENSP00000315674|ensembl:ENSP00000405068 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nop14_human(display_long)|uniprotkb:NOP14(gene name)|psi-mi:NOP14(display_short)|uniprotkb:C4orf9(gene name synonym)|uniprotkb:NOL14(gene name synonym)|uniprotkb:Nucleolar complex protein 14(gene name synonym)|uniprotkb:RES4-25(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001278907.1|refseq:NP_001278908.1|refseq:NP_003694.1|ensembl:ENSG00000087269(gene)|ensembl:ENST00000314262(transcript)|ensembl:ENST00000416614(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0030692"(Noc4p-Nop14p complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007276(Nop14-like protein)|mint:P78316|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:UFAZjZG2vkmiElijCj5ZXZNc35Y9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P78344 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-296519|uniprotkb:O60877|uniprotkb:P78404|uniprotkb:Q0VH00|uniprotkb:Q53EU1|uniprotkb:Q58EZ2|uniprotkb:Q8NI71|uniprotkb:Q96C16|ensembl:ENSP00000340281|ensembl:ENSP00000433371|ensembl:ENSP00000433664|uniprotkb:Q0VH01|uniprotkb:Q2NKW9|uniprotkb:Q49A79 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:if4g2_human(display_long)|uniprotkb:EIF4G2(gene name)|psi-mi:EIF4G2(display_short)|uniprotkb:DAP5(gene name synonym)|uniprotkb:OK/SW-cl.75(orf name)|uniprotkb:p97(gene name synonym)|uniprotkb:Death-associated protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000110321(gene)|ensembl:ENST00000339995(transcript)|ensembl:ENST00000525681(transcript)|ensembl:ENST00000526148(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007507"(heart development)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008219"(cell death)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:P78344|rcsb pdb:3D3M|rcsb pdb:3L6A|rcsb pdb:4IUL|reactome:R-HSA-1169408|refseq:NP_001036024.3|refseq:NP_001166176.1|refseq:NP_001409.3|dip:DIP-31366N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:UIE1Um0s2KJ9hpaa9X6kfZ8enPc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P48507 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1051387|uniprotkb:Q6FHC1|uniprotkb:Q9NPX9|uniprotkb:Q9NU74|uniprotkb:A8K334|uniprotkb:M5A959|uniprotkb:D3DT45|ensembl:ENSP00000359258 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:gsh0_human(display_long)|uniprotkb:Gamma-glutamylcysteine synthetase regulatory subunit(gene name synonym)|uniprotkb:Gamma-ECS regulatory subunit(gene name synonym)|uniprotkb:GCS light chain(gene name synonym)|uniprotkb:Glutamate--cysteine ligase modifier subunit(gene name synonym)|uniprotkb:GCLM(gene name)|psi-mi:GCLM(display_short)|uniprotkb:GLCLR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_002052.1|refseq:NP_001295182.1|ensembl:ENSG00000023909(gene)|ensembl:ENST00000370238(transcript)|go:"GO:0004357"(glutamate-cysteine ligase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006534"(cysteine metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0014823"(response to activity)|go:"GO:0017109"(glutamate-cysteine ligase complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0035226"(glutamate-cysteine ligase catalytic subunit binding)|go:"GO:0035229"(positive regulation of glutamate-cysteine ligase activity)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0042493"|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0097069"(cellular response to thyroxine stimulus)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR023210|interpro:IPR032963|interpro:IPR036812|reactome:R-HSA-174403|reactome:R-HSA-5578999 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:arU12Xm86K7yRxElliA31V7z5d89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q6P1J9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O75607 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62995 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-725485|uniprotkb:O15449|uniprotkb:Q15815|uniprotkb:Q64283|uniprotkb:B4DVK2|uniprotkb:D3DNU3|ensembl:ENSP00000416959 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tra2b_human(display_long)|uniprotkb:TRA2B(gene name)|psi-mi:TRA2B(display_short)|uniprotkb:SFRS10(gene name synonym)|uniprotkb:Transformer-2 protein homolog B(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004584.1|refseq:XP_005247760.1|refseq:NP_001230808.1|refseq:XP_011511374.1|ensembl:ENSG00000136527(gene)|ensembl:ENST00000453386(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P62995|rcsb pdb:2CQC|rcsb pdb:2KXN|rcsb pdb:2RRA|rcsb pdb:2RRB|reactome:R-HSA-72163|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:XP_016862522.1|dip:DIP-42278N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:6uZGeHEDlIVsb2uPeo+9NoR4tDw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8IWA0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2515097|ensembl:ENSP00000314193|uniprotkb:Q9UIX2|uniprotkb:Q9H9U5|uniprotkb:Q96J10|uniprotkb:Q9H8U8|uniprotkb:Q9H9V8 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:wdr75_human(display_long)|uniprotkb:WDR75(gene name)|psi-mi:WDR75(display_short)|uniprotkb:UTP17(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 17 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000115368(gene)|ensembl:ENST00000314761(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_115544.1|refseq:NP_001290025.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:qAYPzmryYALOzvea97t1q/NCsVs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q16629 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-398885|uniprotkb:Q564D3|intact:EBI-11107979|uniprotkb:B4DLU6|uniprotkb:G5E9M3|ensembl:ENSP00000325905 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:srsf7_human(display_long)|uniprotkb:SRSF7(gene name)|psi-mi:SRSF7(display_short)|uniprotkb:Splicing factor 9G8(gene name synonym)|uniprotkb:SFRS7(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001026854.1|refseq:NP_001182375.1|dip:DIP-31790N|ensembl:ENSG00000115875(gene)|ensembl:ENST00000313117(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034651|interpro:IPR035979|interpro:IPR036875|mint:Q16629|rcsb pdb:2HVZ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:12lFDvstcW/ySFKb4LR8KF9AylI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15717 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P31689 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P40227 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P38646 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q07955 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BVJ6 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-473284|uniprotkb:B4DQ08|uniprotkb:E9PEL7|uniprotkb:Q5JYF1|uniprotkb:A8MVQ1|uniprotkb:A8K7A3|ensembl:ENSP00000377944 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ut14a_human(display_long)|uniprotkb:Serologically defined colon cancer antigen 16(gene name synonym)|uniprotkb:Antigen NY-CO-16(gene name synonym)|uniprotkb:UTP14A(gene name)|psi-mi:UTP14A(display_short)|uniprotkb:SDCCAG16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000156697(gene)|ensembl:ENST00000394422(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0032040"(small-subunit processome)|interpro:IPR006709(Small-subunit processome, Utp14)|mint:Q9BVJ6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_001159693.1|refseq:NP_006640.2|dip:DIP-32505N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:vBBHvYYgh4LYP335ktHlQ77Dkfc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62277 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-351850|uniprotkb:P19116|uniprotkb:Q02546|uniprotkb:Q29200|uniprotkb:Q498Y0|uniprotkb:B2R549|ensembl:ENSP00000435777 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs13_human(display_long)|uniprotkb:RPS13(gene name)|psi-mi:RPS13(display_short)|uniprotkb:Small ribosomal subunit protein uS15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001008.1|ensembl:ENSG00000110700(gene)|ensembl:ENST00000525634(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR012606(Ribosomal protein S13/S15, N-terminal)|interpro:IPR023029|mint:P62277|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6OM7|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:GmlWYkXKxX6YwpEtzNABb+ZcytI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NX24 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1050064|uniprotkb:Q9P095|uniprotkb:A6NKY8|intact:EBI-5774108|ensembl:ENSP00000274606 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nhp2_human(display_long)|uniprotkb:Nucleolar protein family A member 2(gene name synonym)|uniprotkb:snoRNP protein NHP2(gene name synonym)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:NOLA2(gene name synonym)|uniprotkb:HSPC286(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060308.1|refseq:NP_001030005.1|ensembl:ENSG00000145912(gene)|ensembl:ENST00000274606(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:Q9NX24|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:ZZchZSzrw15BqMfddUMcaxZRF0w9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NQ55 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1048540|uniprotkb:Q9BW97|uniprotkb:Q9H170|uniprotkb:C9J3F9|ensembl:ENSP00000253107 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ssf1_human(display_long)|uniprotkb:Peter Pan homolog(gene name synonym)|uniprotkb:PPAN(gene name)|psi-mi:PPAN(display_short)|uniprotkb:SSF1(gene name synonym)|uniprotkb:BXDC3(gene name synonym)|uniprotkb:Brix domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001035754.1|refseq:NP_064615.3|ensembl:ENSG00000130810(gene)|ensembl:ENST00000253107(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR007109(Brix)|mint:Q9NQ55 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:wIgMQj/xJrj5eExsyZD6BeamQOQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q13601 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q6ZRQ5 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-718662|uniprotkb:Q5THT2|uniprotkb:Q68CQ6|uniprotkb:Q68D32|uniprotkb:D6R9Y8|uniprotkb:D6RBQ4|uniprotkb:E1P529|ensembl:ENSP00000275053|ensembl:ENSP00000508046 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mms22_human(display_long)|uniprotkb:MMS22L(gene name)|psi-mi:MMS22L(display_short)|uniprotkb:C6orf167(gene name synonym)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_940870.2|refseq:XP_006715493.1|ensembl:ENSG00000146263(gene)|ensembl:ENST00000275053(transcript)|ensembl:ENST00000683635(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005829"(cytosol)|go:"GO:0031297"(replication fork processing)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR029424|interpro:IPR029425|interpro:IPR042320|go:"GO:0005654"(nucleoplasm) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:fdwESkbP/HHMiKQ1EJHW2FmD5jM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62136 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q12789 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-357956|uniprotkb:B2RP21|uniprotkb:Q12838|uniprotkb:Q6DKN9|uniprotkb:Q9Y4W9|ensembl:ENSP00000348510 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tf3c1_human(display_long)|uniprotkb:GTF3C1(gene name)|psi-mi:GTF3C1(display_short)|uniprotkb:Transcription factor IIIC subunit alpha(gene name synonym)|uniprotkb:TF3C-alpha(gene name synonym)|uniprotkb:Transcription factor IIIC 220 kDa subunit(gene name synonym)|uniprotkb:TFIIIC box B-binding subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001511.2|refseq:NP_001273171.1|dip:DIP-38212N|ensembl:ENSG00000077235(gene)|ensembl:ENST00000356183(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009304"(tRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007309(B-block binding subunit of TFIIIC)|interpro:IPR035625|interpro:IPR044210|mint:Q12789|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:1celgxr5g9oKbPr0x1SvI6S7hNE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8NE71 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-720571|uniprotkb:A2BF75|uniprotkb:O14897|uniprotkb:Q69YP6|ensembl:ENSP00000313603|ensembl:ENSP00000373082|ensembl:ENSP00000389065|ensembl:ENSP00000411327|ensembl:ENSP00000412553|ensembl:ENSP00000413319|ensembl:ENSP00000414373 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:abcf1_human(display_long)|uniprotkb:ATP-binding cassette 50(gene name synonym)|uniprotkb:TNF-alpha-stimulated ABC protein(gene name synonym)|uniprotkb:ABCF1(gene name)|psi-mi:ABCF1(display_short)|uniprotkb:ABC50(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001020262.1|refseq:NP_001081.1|dip:DIP-50666N|ensembl:ENSG00000204574(gene)|ensembl:ENSG00000206490(gene)|ensembl:ENSG00000225989(gene)|ensembl:ENSG00000231129(gene)|ensembl:ENSG00000232169(gene)|ensembl:ENSG00000236149(gene)|ensembl:ENSG00000236342(gene)|ensembl:ENST00000326195(transcript)|ensembl:ENST00000383588(transcript)|ensembl:ENST00000419893(transcript)|ensembl:ENST00000423247(transcript)|ensembl:ENST00000426219(transcript)|ensembl:ENST00000457078(transcript)|ensembl:ENST00000457111(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008494"(translation activator activity)|go:"GO:0016020"(membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|mint:Q8NE71|rcsb pdb:5ZXD|reactome:R-HSA-382556 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:DdEbnAZo4bv75DRSzSmcdNo6QsM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P09874 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62750 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96MU7 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2849854|uniprotkb:Q4W5Q3|uniprotkb:Q7Z622|uniprotkb:Q8TF35|intact:EBI-28984617|ensembl:ENSP00000339245|ensembl:ENSP00000479213 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ytdc1_human(display_long)|uniprotkb:YTHDC1(gene name)|psi-mi:YTHDC1(display_short)|uniprotkb:KIAA1966(gene name synonym)|uniprotkb:YT521(gene name synonym)|uniprotkb:Splicing factor YT521(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001026902.1|refseq:NP_588611.2|ensembl:ENSP00000339245|ensembl:ENST00000355665|ensembl:ENSP00000347888|ensembl:ENST00000613637|ensembl:ENSP00000484604|ensembl:ENSP00000479213|refseq:NP_001317627.1|rcsb pdb:6T01|rcsb pdb:6T02|rcsb pdb:6T03|rcsb pdb:6T04|rcsb pdb:6T05|rcsb pdb:6SZY|rcsb pdb:6T06|rcsb pdb:6T07|rcsb pdb:6T08|rcsb pdb:6T09|rcsb pdb:6T0A|rcsb pdb:6T0C|rcsb pdb:6T0D|rcsb pdb:6T0O|rcsb pdb:6T0X|rcsb pdb:6T0Z|rcsb pdb:6T10|rcsb pdb:6T11|rcsb pdb:6T12|rcsb pdb:6WE8|rcsb pdb:6WE9|rcsb pdb:6WEA|rcsb pdb:6YKE|rcsb pdb:6YKI|rcsb pdb:6YKJ|rcsb pdb:6YKZ|rcsb pdb:6YL0|rcsb pdb:6YL8|rcsb pdb:6YL9|rcsb pdb:6YM2|rcsb pdb:6YM6|rcsb pdb:6YM7|rcsb pdb:6YM8|rcsb pdb:6YNI|rcsb pdb:6YNJ|rcsb pdb:6YNK|rcsb pdb:6YNL|rcsb pdb:6YNM|rcsb pdb:6YNN|rcsb pdb:6YNO|rcsb pdb:6YNP|rcsb pdb:6YOQ|rcsb pdb:6ZCM|rcsb pdb:6ZCN|rcsb pdb:6ZD9|ensembl:ENSG00000083896(gene)|ensembl:ENSG00000275272(gene)|ensembl:ENST00000344157(transcript)|ensembl:ENST00000615500(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048160"(primary follicle stage)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR007275(YT521-B-like protein)|rcsb pdb:2YUD|rcsb pdb:4R3H|rcsb pdb:4R3I|rcsb pdb:6RT4|rcsb pdb:6RT5|rcsb pdb:6RT6|rcsb pdb:6RT7|rcsb pdb:6SYZ|rcsb pdb:6SZ1|rcsb pdb:6SZ2|rcsb pdb:6SZ3|rcsb pdb:6SZL|rcsb pdb:6SZN|rcsb pdb:6SZR|rcsb pdb:6SZT|rcsb pdb:6SZX - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:vfZLRHOJvCdw6OIA9xeqeSgJZgE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14690 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-300028|uniprotkb:Q9H4P1|ensembl:ENSP00000358812|uniprotkb:Q86VQ8|uniprotkb:Q5W093|uniprotkb:Q2TA92|uniprotkb:Q6P2J3 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rrp5_human(display_long)|uniprotkb:PDCD11(gene name)|psi-mi:PDCD11(display_short)|uniprotkb:KIAA0185(gene name synonym)|uniprotkb:Programmed cell death protein 11(gene name synonym)|uniprotkb:NF-kappa-B-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000148843(gene)|ensembl:ENST00000369797(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032040"(small-subunit processome)|interpro:IPR003029(S1, RNA binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008847(Suppressor of forked)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|mint:Q14690|rcsb pdb:1WI5|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0006397"(mRNA processing)|refseq:NP_055791.1|refseq:XP_011537841.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:G3h7KMQzbRdyetWmb3uVBqXJWu09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O60716 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P68104 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UBX3 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0071422"(succinate transmembrane transport)|ensembl:ENSG00000183048(gene)|ensembl:ENST00000350690(transcript)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006811"(ion transport)|go:"GO:0006835"(dicarboxylic acid transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|reactome:R-HSA-70263|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y277 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354196|uniprotkb:Q9UIS0|ensembl:ENSP00000022615 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:vdac3_human(display_long)|uniprotkb:VDAC3(gene name)|psi-mi:VDAC3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001129166.1|refseq:NP_005653.3|ensembl:ENSG00000078668(gene)|ensembl:ENST00000022615(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015853"(adenine transport)|go:"GO:0016020"(membrane)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030271|mint:Q9Y277|reactome:R-HSA-5689880|reactome:R-HSA-8949215 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:En6g89Dp+C4s1ArGYJyVfUBVsO09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P78371 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P07437 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P61619 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-358919|uniprotkb:Q5JPF8|uniprotkb:P38378|uniprotkb:P57726|uniprotkb:Q8N3U3|uniprotkb:Q8NC71|uniprotkb:Q9BU16|uniprotkb:Q9Y2R3|uniprotkb:Q8N0Z4|ensembl:ENSP00000243253 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:s61a1_human(display_long)|uniprotkb:SEC61A1(gene name)|psi-mi:SEC61A1(display_short)|uniprotkb:SEC61A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_037468.1|ensembl:ENSG00000058262(gene)|ensembl:ENST00000243253(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0039019"(pronephric nephron development)|go:"GO:0043022"(ribosome binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|mint:P61619|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:C+EzS02H/FYMX2nyfksXpRMs8G09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UNX4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-727436|ensembl:ENSP00000308179 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:wdr3_human(display_long)|uniprotkb:WDR3(gene name)|psi-mi:WDR3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006775.1|ensembl:ENSG00000065183(gene)|ensembl:ENST00000349139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:Q9UNX4|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:aslkTiEP+9ytaN6cc+SC+TzOxUg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8IZL8 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-716449|intact:EBI-28969510|ensembl:ENSP00000460300|ensembl:ENSP00000461625|uniprotkb:O15450|uniprotkb:Q5EGN3|uniprotkb:Q6NTE6|uniprotkb:Q96FT1|uniprotkb:Q9BU60 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pelp1_human(display_long)|uniprotkb:Modulator of non-genomic activity of estrogen receptor(gene name synonym)|uniprotkb:Transcription factor HMX3(gene name synonym)|uniprotkb:PELP1(gene name)|psi-mi:PELP1(display_short)|uniprotkb:HMX3(gene name synonym)|uniprotkb:MNAR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000141456(gene)|ensembl:ENST00000572293(transcript)|ensembl:ENST00000574876(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012583(NUC201)|interpro:IPR016024(Armadillo-type fold)|mint:Q8IZL8|reactome:R-HSA-6791226|reactome:R-HSA-8849473|interpro:IPR012980(Protein of unknown function NUC202)|ensembl:ENSP00000460300|ensembl:ENSP00000461625|refseq:NP_055204.3|refseq:NP_001265170.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:iu03DsintVoo3gWzZX14SlHE0ao9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15269 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-722224|uniprotkb:Q96A77|uniprotkb:B2RAG8|ensembl:ENSP00000291576 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pwp2_human(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:PWP2H(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005040.2|refseq:XP_006723973.1|refseq:XP_011507205.1|ensembl:ENSG00000241945(gene)|ensembl:ENST00000291576(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:PYs2LKd3EMjAnp0engZvZn0CeBo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P31040 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O94906 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-536755|uniprotkb:O95109|uniprotkb:Q5VXS5|uniprotkb:Q9H3Z1|uniprotkb:Q9H4T9|uniprotkb:Q9H4U8|uniprotkb:Q9NTE6|ensembl:ENSP00000266079|uniprotkb:B2RAR5|uniprotkb:B3KMC6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:prp6_human(display_long)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:PRPF6(gene name)|psi-mi:PRPF6(display_short)|uniprotkb:C20orf14(gene name synonym)|uniprotkb:Androgen receptor N-terminal domain-transactivating protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000101161(gene)|ensembl:ENST00000266079(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006403"(RNA localization)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|mint:O94906|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_036601.2|dip:DIP-29006N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:M5ovIXl+1ob6VSKbXZUGU73J7Jk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P23528 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629|ensembl:ENSP00000432660 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005498.1|ensembl:ENSG00000172757(gene)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|ensembl:ENST00000308162(transcript)|ensembl:ENST00000525451(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009615"(response to virus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0031258"(lamellipodium membrane)|dip:DIP-33000N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NQT5 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62263 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352783|ensembl:ENSP00000311028|ensembl:ENSP00000385425|uniprotkb:P06366|uniprotkb:Q5BJI0|uniprotkb:B2R5G5|uniprotkb:D3DQG5|ensembl:ENSP00000385958|ensembl:ENSP00000428509 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs14_human(display_long)|uniprotkb:RPS14(gene name)|psi-mi:RPS14(display_short)|uniprotkb:Small ribosomal subunit protein uS11(gene name synonym)|uniprotkb:PRO2640(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000164587(gene)|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001020242.1|refseq:NP_005608.1|refseq:NP_001020241.1|ensembl:ENST00000312037(transcript)|ensembl:ENST00000401695(transcript)|ensembl:ENST00000407193(transcript)|ensembl:ENST00000521466(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001971(Ribosomal protein S11)|interpro:IPR018102|interpro:IPR036967|mint:P62263|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:ee3bJ5JYFaZXyCCRG9Wooopyz2o9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H8H2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-395655|uniprotkb:Q5K6N2|uniprotkb:Q5K6N3|uniprotkb:Q5K6N4|uniprotkb:Q5VZJ4|uniprotkb:Q5VZJ9|uniprotkb:Q96E91|uniprotkb:Q96NY2|uniprotkb:Q96SX5|uniprotkb:Q9H5K6|ensembl:ENSP00000361226|ensembl:ENSP00000361232 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx31_human(display_long)|uniprotkb:DEAD box protein 31(gene name synonym)|uniprotkb:Helicain(gene name synonym)|uniprotkb:DDX31(gene name)|psi-mi:DDX31(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_073616.6|refseq:NP_619526.1|ensembl:ENSG00000125485(gene)|ensembl:ENST00000372153(transcript)|ensembl:ENST00000372159(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|refseq:NP_001309269.1|refseq:NP_001309273.1|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|mint:Q9H8H2|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:HaC4SAnIvujAJVEcn/88Wij/zTM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8NI36 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2512413|ensembl:ENSP00000423067|ensembl:ENSP00000479950|uniprotkb:A2RUS4|uniprotkb:Q8N1Q2|uniprotkb:Q68E02 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:wdr36_human(display_long)|uniprotkb:WDR36(gene name)|psi-mi:WDR36(display_short)|uniprotkb:T-cell activation WD repeat-containing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000134987(gene)|ensembl:ENST00000506538(transcript)|ensembl:ENST00000612402(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0007601"(visual perception)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|go:"GO:0050896"(response to stimulus)|interpro:IPR001680(WD40 repeat)|interpro:IPR007319(Small-subunit processome, Utp21)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR036322|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|refseq:NP_644810.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:97Qc0ehUPTjCBcn3gjr0FY8Nnus9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O75152 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-748480|uniprotkb:Q6AHY4|uniprotkb:Q6AHY9|uniprotkb:Q6AW79|uniprotkb:Q6AWA1|uniprotkb:Q6PJK4|uniprotkb:Q86XZ7|ensembl:ENSP00000333253|ensembl:ENSP00000356179|ensembl:ENSP00000356181|ensembl:ENSP00000356183|ensembl:ENSP00000491830 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:zc11a_human(display_long)|uniprotkb:ZC3H11A(gene name)|psi-mi:ZC3H11A(display_short)|uniprotkb:KIAA0663(gene name synonym)|uniprotkb:ZC3HDC11A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:XP_006711736.1|refseq:NP_055642.3|refseq:XP_011508501.1|refseq:XP_011508502.1|refseq:XP_011508503.1|refseq:XP_011508504.1|refseq:NP_001306167.1|refseq:NP_001306168.1|refseq:XP_005245700.1|refseq:XP_005245701.1|refseq:XP_016858445.1|refseq:XP_016858446.1|refseq:XP_016858447.1|refseq:XP_016858448.1|ensembl:ENSG00000058673(gene)|ensembl:ENST00000332127(transcript)|ensembl:ENST00000367210(transcript)|ensembl:ENST00000367212(transcript)|ensembl:ENST00000367214(transcript)|ensembl:ENST00000639812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR041686|mint:O75152|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:BJfX/K7kBXQGQx6l+Y2xBtwyJAw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8TED0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1048301|uniprotkb:Q6IA60|uniprotkb:Q96E08|uniprotkb:Q9H9F8|uniprotkb:B4DU75|uniprotkb:B4DXK8|ensembl:ENSP00000296792 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:utp15_human(display_long)|uniprotkb:UTP15(gene name)|psi-mi:UTP15(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001271359.1|refseq:NP_001271360.1|refseq:NP_115551.2|refseq:XP_011541982.1|ensembl:ENSG00000164338(gene)|ensembl:ENST00000296792(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006364"(rRNA processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018983|interpro:IPR019775|interpro:IPR036322|mint:Q8TED0|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:acCnB6DdQIhfvM1C9EQVQdoqHvo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62081 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354360|uniprotkb:Q6IPH1|uniprotkb:P23821|uniprotkb:P24818|uniprotkb:Q57Z92|ensembl:ENSP00000385018|ensembl:ENSP00000385286|ensembl:ENSP00000495273|ensembl:ENSP00000496654|ensembl:ENSP00000496757 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs7_human(display_long)|uniprotkb:RPS7(gene name)|psi-mi:RPS7(display_short)|uniprotkb:Small ribosomal subunit protein eS7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001002.1|ensembl:ENSG00000171863(gene)|ensembl:ENST00000403564(transcript)|ensembl:ENST00000406376(transcript)|ensembl:ENST00000462576(transcript)|ensembl:ENST00000645674(transcript)|ensembl:ENST00000646909(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62081|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6G4S - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:l4aG6I34lmzYhNapbdv2CAAwRwg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q5QJE6 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-5666736|ensembl:ENSP00000411010|uniprotkb:Q53H59|uniprotkb:Q86WX9|uniprotkb:Q76MJ8|uniprotkb:Q12987|uniprotkb:Q6TLI0|uniprotkb:Q5TFJ4 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tdif2_human(display_long)|uniprotkb:ERBP(gene name synonym)|uniprotkb:Estrogen receptor-binding protein(gene name synonym)|uniprotkb:LPTS-interacting protein 2(gene name synonym)|uniprotkb:TDIF2(gene name synonym)|uniprotkb:Terminal deoxynucleotidyltransferase-interacting factor 2(gene name synonym)|uniprotkb:DNTTIP2(gene name)|psi-mi:DNTTIP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000067334(gene)|ensembl:ENST00000436063(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR014810(Fcf2 pre-rRNA processing)|interpro:IPR039883|refseq:NP_055412.2 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:GSN2/hZ+HZb29LuBvv2RVMawmNA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P48729 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1383726|uniprotkb:Q96HD2|uniprotkb:Q5U046|uniprotkb:Q5U047|uniprotkb:Q6FGA2|uniprotkb:Q4JJA0|uniprotkb:Q9UDK3|intact:EBI-11048253|uniprotkb:D3DQG0|uniprotkb:D3DQG1|uniprotkb:Q71TU5|ensembl:ENSP00000367074 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:kc1a_human(display_long)|uniprotkb:CSNK1A1(gene name)|psi-mi:CSNK1A1(display_short)|uniprotkb:CK1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001020276.1|refseq:NP_001883.4|refseq:NP_001258670.1|refseq:NP_001258671.1|dip:DIP-40367N|ensembl:ENSG00000113712(gene)|ensembl:ENST00000377843(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051301"(cell division)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904424"(regulation of GTP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48729|rcsb pdb:5FQD|rcsb pdb:6GZD|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5635838 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:2rG1/sMVnsRKUEWsLhLAyHvqPnY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y5J1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-592816|uniprotkb:Q9H4N6|ensembl:ENSP00000225298 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:utp18_human(display_long)|uniprotkb:WD repeat-containing protein 50(gene name synonym)|uniprotkb:UTP18(gene name)|psi-mi:UTP18(display_short)|uniprotkb:CGI-48(orf name)|uniprotkb:CDABP0061(orf name)|uniprotkb:WDR50(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_057085.2|ensembl:ENSG00000011260(gene)|ensembl:ENST00000225298(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9Y5J1|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:l873IUyfCql4N9VelHPuUEqpzRY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y5B9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1046849|uniprotkb:Q6GMT8|uniprotkb:Q6P2F1|uniprotkb:Q6PJM1|uniprotkb:Q9NRX0|ensembl:ENSP00000216297 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:sp16h_human(display_long)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:SUPT16H(gene name)|psi-mi:SUPT16H(display_short)|uniprotkb:FACT140(gene name synonym)|uniprotkb:FACTP140(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000092201(gene)|ensembl:ENST00000216297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|mint:Q9Y5B9|rcsb pdb:4Z2M|rcsb pdb:4Z2N|rcsb pdb:5E5B|rcsb pdb:5UMT|rcsb pdb:5UMU|rcsb pdb:5XM2|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|refseq:NP_009123.1|dip:DIP-42757N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:jLK5dOF3mEyI0UbZhcNgtdlG+WI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62280 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P46776 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-350581|uniprotkb:B2R4B3|ensembl:ENSP00000346015 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl27a_human(display_long)|uniprotkb:RPL27A(gene name)|psi-mi:RPL27A(display_short)|uniprotkb:Large ribosomal subunit protein uL15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000981.1|ensembl:ENSG00000166441(gene)|ensembl:ENST00000314138(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001196(Ribosomal protein L15)|interpro:IPR021131|interpro:IPR027386|interpro:IPR030878|interpro:IPR036227|mint:P46776|rcsb pdb:4BXF|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6IP6|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6OM7|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:6IP5|dip:DIP-33121N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:tUezMQBw+SWmLYq8M0pkLCF8vO89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NYH9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-749211|uniprotkb:Q8IX96|uniprotkb:Q96BL2|uniprotkb:Q9NQ91|ensembl:ENSP00000261708 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:utp6_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated antigen 66(gene name synonym)|uniprotkb:Multiple hat domains protein(gene name synonym)|uniprotkb:UTP6(gene name)|psi-mi:UTP6(display_short)|uniprotkb:C17orf40(gene name synonym)|uniprotkb:HCA66(gene name synonym)|uniprotkb:MHAT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060898.2|ensembl:ENSG00000108651(gene)|ensembl:ENST00000261708(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0030515"(snoRNA binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013949(U3 small nucleolar RNA-associated protein 6)|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:hMKHMRXUFqGjWKsyi9MedHMilhc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P13639 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P25490 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O60832 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-713091|ensembl:ENSP00000358563|uniprotkb:O43845|uniprotkb:Q96G67|uniprotkb:Q9Y505|uniprotkb:F5BSB3 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:dkc1_human(display_long)|uniprotkb:Dyskerin(gene name synonym)|uniprotkb:Nucleolar protein family A member 4(gene name synonym)|uniprotkb:snoRNP protein DKC1(gene name synonym)|uniprotkb:Nopp140-associated protein of 57 kDa(gene name synonym)|uniprotkb:Nucleolar protein NAP57(gene name synonym)|uniprotkb:CBF5 homolog(gene name synonym)|uniprotkb:DKC1(gene name)|psi-mi:DKC1(display_short)|uniprotkb:NOLA4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR032819|interpro:IPR036974|mint:O60832|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901|interpro:IPR002478(PUA)|ensembl:ENSG00000130826(gene)|ensembl:ENST00000369550(transcript)|go:"GO:0000455"(enzyme-directed rRNA pseudouridine synthesis)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003720"(telomerase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990481"(mRNA pseudouridine synthesis)|go:"GO:0006396"(RNA processing)|refseq:NP_001354.1|refseq:NP_001135935.1|refseq:NP_001275676.1|dip:DIP-40645N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:njIdhtX9m37BslwxyAAV/JoRrHo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P60842 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15021 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1044041|uniprotkb:Q8N6U3|ensembl:ENSP00000325017|uniprotkb:D3DUR4 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cnd1_human(display_long)|uniprotkb:NCAPD2(gene name)|psi-mi:NCAPD2(display_short)|uniprotkb:CAPD2(gene name synonym)|uniprotkb:KIAA0159(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit D2(gene name synonym)|uniprotkb:Chromosome condensation-related SMC-associated protein 1(gene name synonym)|uniprotkb:Chromosome-associated protein D2(gene name synonym)|uniprotkb:XCAP-D2 homolog(gene name synonym)|uniprotkb:CNAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055680.3|ensembl:ENSG00000010292(gene)|ensembl:ENST00000315579(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR007673(Non-SMC condensin subunit, XCAP-D2/Cnd1)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024324|interpro:IPR026971|interpro:IPR032682|mint:Q15021|reactome:R-HSA-2514853 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:lFz1E3CjOD76OsuGtokfR7Ujvnw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q13895 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-358049|uniprotkb:Q6P5W4|uniprotkb:Q86W44|uniprotkb:Q96IP8|ensembl:ENSP00000230340 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:byst_human(display_long)|uniprotkb:BYSL(gene name)|psi-mi:BYSL(display_short)|uniprotkb:ENP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004044.3|dip:DIP-50092N|ensembl:ENSG00000112578(gene)|ensembl:ENST00000230340(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045177"(apical part of cell)|go:"GO:1904749"(regulation of protein localization to nucleolus)|interpro:IPR007955(Bystin)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:QdpF9XYm2gFc5ZodqaGvqTM6XNk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y2R4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-395458|uniprotkb:Q86YG1|uniprotkb:Q8N213|uniprotkb:Q9NVE0|uniprotkb:Q9Y482|ensembl:ENSP00000479504|ensembl:ENSP00000480030 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx52_human(display_long)|uniprotkb:DDX52(gene name)|psi-mi:DDX52(display_short)|uniprotkb:ROK1(gene name synonym)|uniprotkb:DEAD box protein 52(gene name synonym)|uniprotkb:ATP-dependent RNA helicase ROK1-like(gene name synonym)|uniprotkb:HUSSY-19(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_008941.3|ensembl:ENSG00000277594(gene)|ensembl:ENSG00000278053(gene)|ensembl:ENST00000615769(transcript)|ensembl:ENST00000617633(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044764|mint:Q9Y2R4|rcsb pdb:3DKP|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_001278405.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:M3yY9StxHlLGPK0WOqPHwgnmwLU9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96CB8 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1049156|uniprotkb:Q3B6Z3|uniprotkb:Q9HD71|uniprotkb:B2RC48|ensembl:ENSP00000340737|ensembl:ENSP00000378221|ensembl:ENSP00000415433 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:int12_human(display_long)|uniprotkb:PHD finger protein 22(gene name synonym)|uniprotkb:INTS12(gene name)|psi-mi:INTS12(display_short)|uniprotkb:PHF22(gene name synonym)|uniprotkb:SBBI22(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001135943.1|refseq:NP_065128.2|refseq:XP_011530445.1|refseq:XP_011530447.1|refseq:XP_005263205.1|ensembl:ENSG00000138785(gene)|ensembl:ENST00000340139(transcript)|ensembl:ENST00000394735(transcript)|ensembl:ENST00000451321(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR039053|interpro:IPR039054|reactome:R-HSA-6807505|dip:DIP-48479N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:zKa0nY59t/jyu7NJBc+y4zKQM1A9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y3A2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2876697|ensembl:ENSP00000362105|uniprotkb:B4DJC6|uniprotkb:Q9BS98|uniprotkb:Q9NS31|uniprotkb:Q5VT93|intact:EBI-2963233|uniprotkb:A8K785|uniprotkb:D3DPT7 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:utp11_human(display_long)|uniprotkb:HDCMB12P(orf name)|uniprotkb:UTP11(gene name)|psi-mi:UTP11(display_short)|uniprotkb:UTP11-like protein(gene name synonym)|uniprotkb:UTP11L(gene name synonym)|uniprotkb:CGI-94(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000183520(gene)|ensembl:ENST00000373014(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0032040"(small-subunit processome)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR007144(Small-subunit processome, Utp11)|mint:Q9Y3A2|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_057121.2 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:JTS/jMbRZE3NifB95Nqh0foDUKI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P43246 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q02978 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|ensembl:ENSP00000225665|uniprotkb:F5GY65 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_003553.2|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|mint:Q02978|reactome:R-HSA-70263|ensembl:ENSG00000108528(gene)|ensembl:ENST00000225665(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015367"("oxoglutarate:malate antiporter activity")|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P15880 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q5SY16 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1055462|uniprotkb:Q4VBY3|uniprotkb:Q6P472|uniprotkb:Q7L4D6|uniprotkb:Q96EE0|uniprotkb:Q9H5L4|uniprotkb:Q2NL84|ensembl:ENSP00000366934 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nol9_human(display_long)|uniprotkb:NOL9(gene name)|psi-mi:NOL9(display_short)|uniprotkb:Nucleolar protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_078930.3|refseq:XP_011540449.1|ensembl:ENST00000377705(transcript)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051731"(polynucleotide 5'-hydroxyl-kinase activity)|interpro:IPR027417|interpro:IPR032319|mint:Q5SY16|reactome:R-HSA-6791226|ensembl:ENSG00000162408(gene)|refseq:XP_016857827.1|refseq:XP_016857828.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:IWGhuh/G+MlTxlSXEcIml8tvK7Y9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NZ01 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P54886 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1210304|ensembl:ENSP00000360268|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000059573(gene)|ensembl:ENST00000371224(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006592"(ornithine biosynthetic process)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|refseq:NP_001017423.1|refseq:NP_002851.2|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P40937 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-712376|ensembl:ENSP00000408295|uniprotkb:A8MZ62|uniprotkb:B3KSX8 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rfc5_human(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_031396.1|refseq:NP_853556.2|ensembl:ENSG00000111445(gene)|ensembl:ENST00000454402(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P40937|rcsb pdb:1LFS|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:XP_011536945.1|refseq:XP_011536947.1|refseq:NP_001123584.1|refseq:NP_001123585.1|dip:DIP-36433N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:F7oadHDk6fkhHn+3rDF9K2JHSl49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62854 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NX58 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-713507|uniprotkb:Q6FI78|uniprotkb:Q9NYS1|ensembl:ENSP00000345917|ensembl:ENSP00000397367|uniprotkb:D3DVS4 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:lyar_human(display_long)|uniprotkb:LYAR(gene name)|psi-mi:LYAR(display_short)|uniprotkb:PNAS-5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000145220(gene)|ensembl:ENST00000343470(transcript)|ensembl:ENST00000452476(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|interpro:IPR041010|mint:Q9NX58|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZVH|refseq:NP_001139197.1|refseq:NP_060286.1|refseq:XP_011511807.1|refseq:XP_011511808.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:AJ+5B1LahcUlSWQehJ2vxY+8pwY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BWF3 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2856454|uniprotkb:B3KUN0|uniprotkb:Q8WU85|uniprotkb:Q6P1P2|uniprotkb:O02916|uniprotkb:Q4VC48|uniprotkb:B4E1U0|uniprotkb:E7EQS3|ensembl:ENSP00000309166|ensembl:ENSP00000386561|ensembl:ENSP00000386894 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rbm4_human(display_long)|uniprotkb:RBM4(gene name)|psi-mi:RBM4(display_short)|uniprotkb:RBM4A(gene name synonym)|uniprotkb:Lark homolog(gene name synonym)|uniprotkb:RNA-binding motif protein 4(gene name synonym)|uniprotkb:RNA-binding motif protein 4a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001185772.1|refseq:NP_002887.2|refseq:NP_001185773.1|dip:DIP-44199N|ensembl:ENSG00000173933(gene)|ensembl:ENST00000310092(transcript)|ensembl:ENST00000408993(transcript)|ensembl:ENST00000409406(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002190"(cap-independent translational initiation)|go:"GO:0002192"(IRES-dependent translational initiation of linear mRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097158"(pre-mRNA intronic pyrimidine-rich binding)|go:"GO:0097167"(circadian regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR034897|interpro:IPR034898|interpro:IPR035979|mint:Q9BWF3|rcsb pdb:2DNQ|reactome:R-HSA-400253|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:hbW6dv/AEWQz3mWvA2/9n8h/bbA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P12277 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NWH9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2814558|uniprotkb:A8K5V8|uniprotkb:Q6ZNF2|uniprotkb:B2RTX3|uniprotkb:Q9H7C3|uniprotkb:Q658J7|uniprotkb:Q52MB3|uniprotkb:Q9H8U9|uniprotkb:Q86TK6|uniprotkb:Q2VPK7|ensembl:ENSP00000369887 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:sltm_human(display_long)|uniprotkb:SLTM(gene name)|psi-mi:SLTM(display_short)|uniprotkb:MET(gene name synonym)|uniprotkb:Modulator of estrogen-induced transcription(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:XP_006720753.1|refseq:NP_079031.2|refseq:NP_001013865.1|refseq:XP_016878069.1|ensembl:ENSG00000137776(gene)|ensembl:ENST00000380516(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034780|interpro:IPR035979|interpro:IPR036361|mint:Q9NWH9 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:/B0FdPpFi/TvMq9aGjuLOQ3zIuo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P33993 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P08243 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-722989|uniprotkb:P08184|uniprotkb:Q15666|uniprotkb:Q549T9|uniprotkb:Q96HD0|ensembl:ENSP00000175506|ensembl:ENSP00000377845|ensembl:ENSP00000377846|uniprotkb:A4D1I8|uniprotkb:D6W5R3|uniprotkb:B4DXZ1|uniprotkb:B7ZAA9|uniprotkb:E9PCI3|uniprotkb:E9PCX6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:asns_human(display_long)|uniprotkb:Glutamine-dependent asparagine synthetase(gene name synonym)|uniprotkb:Cell cycle control protein TS11(gene name synonym)|uniprotkb:ASNS(gene name)|psi-mi:ASNS(display_short)|uniprotkb:TS11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001171546.1|refseq:NP_001171547.1|refseq:NP_001171548.1|refseq:NP_001664.3|refseq:NP_597680.2|refseq:NP_899199.2|ensembl:ENSG00000070669(gene)|ensembl:ENST00000175506(transcript)|ensembl:ENST00000394308(transcript)|ensembl:ENST00000394309(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0031427"(response to methotrexate)|go:"GO:0032354"(response to follicle-stimulating hormone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|rcsb pdb:6GQ3|reactome:R-HSA-380994|reactome:R-HSA-8963693|reactome:R-HSA-9633012|reactome:R-HSA-9648895 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:McR8Ve0DzWhe3JWMYLsCRChiBaY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P04792 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N - - crc64:1B4DC44A6F6606D5 figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96PK6 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O43290 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-607761|ensembl:ENSP00000310448|uniprotkb:A6NDN1|uniprotkb:Q53GB5 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:snut1_human(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated 110 kDa protein(gene name synonym)|uniprotkb:SART1(gene name)|psi-mi:SART1(display_short)|uniprotkb:SNU66 homolog(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen recognized by T-cells 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000175467(gene)|ensembl:ENST00000312397(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000481"(maturation of 5S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR005011(SART-1 protein)|mint:O43290|rcsb pdb:4PYU|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|refseq:NP_005137.1|dip:DIP-33360N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:egvWHy7UXW+MkGtGEW984yvRU9k9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O95674 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-3913685|uniprotkb:Q5TDY5|uniprotkb:Q5TDY3|uniprotkb:Q5TDY2|uniprotkb:Q9NTT2|uniprotkb:Q9BYK5|uniprotkb:Q5TDY4|uniprotkb:D3DW04|uniprotkb:B2RDC6|ensembl:ENSP00000419879 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cds2_human(display_long)|uniprotkb:CDS2(gene name)|psi-mi:CDS2(display_short)|uniprotkb:CDP-DAG synthase 2(gene name synonym)|uniprotkb:CDP-DG synthase 2(gene name synonym)|uniprotkb:CDP-diacylglycerol synthase 2(gene name synonym)|uniprotkb:CDP-diglyceride pyrophosphorylase 2(gene name synonym)|uniprotkb:CDP-diglyceride synthase 2(gene name synonym)|uniprotkb:"CTP:phosphatidate cytidylyltransferase 2"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_003809.1|ensembl:ENSG00000101290(gene)|ensembl:ENST00000460006(transcript)|go:"GO:0004605"(phosphatidate cytidylyltransferase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006655"(phosphatidylglycerol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR000374(Phosphatidate cytidylyltransferase)|interpro:IPR016720(Phosphatidate cytidylyltransferase, eukaryota)|mint:O95674|reactome:R-HSA-1483148 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:tCRLIDMiesBx7QPKIycdX3Igz589606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8NDX6 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2602428|uniprotkb:A8K9M9|ensembl:ENSP00000409463 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:zn740_human(display_long)|uniprotkb:ZNF740(gene name)|psi-mi:ZNF740(display_short)|uniprotkb:TB7(gene name synonym)|uniprotkb:OriLyt TD-element-binding protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001004304.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000139651(gene)|ensembl:ENST00000416904(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:2i7f+rUftAUiFntFARDjwFBLfrs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q16850 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2680495|intact:EBI-21358836|uniprotkb:A0A0C4DFL7|uniprotkb:O00770|uniprotkb:Q99868|uniprotkb:Q8N1A8|uniprotkb:O00772|uniprotkb:Q16784|uniprotkb:B2RAI4|uniprotkb:B4DJ55|uniprotkb:A4D1F8 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cp51a_human(display_long)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450 51A1(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:Cytochrome P450LI(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:CYP51A1(gene name)|psi-mi:CYP51A1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 mint:Q16850|refseq:NP_000777.1|refseq:NP_001139624.1|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002403(Cytochrome P450, E-class, group IV)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|rcsb pdb:3JUS|rcsb pdb:3JUV|rcsb pdb:3LD6|rcsb pdb:4UHI|rcsb pdb:4UHL|rcsb pdb:6Q2T|rcsb pdb:6UEZ|reactome:R-HSA-191273|reactome:R-HSA-211976|reactome:R-HSA-2426168|reactome:R-HSA-9619665|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006694"(steroid biosynthetic process)|interpro:IPR036396 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:yrFu9QoUi7oRnhwLxzbC3e/jhUE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q86UV5 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2512161|uniprotkb:Q2M3I4|uniprotkb:Q5SZI4|uniprotkb:Q96IQ3|uniprotkb:Q8N3F6|uniprotkb:Q9NUJ6|uniprotkb:Q9H5N3|uniprotkb:Q9H5T7|uniprotkb:Q96F64|uniprotkb:Q9NXR0|uniprotkb:Q6NX53|uniprotkb:Q5T3T5|intact:EBI-2512805|uniprotkb:B7ZKS7|ensembl:ENSP00000309262 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ubp48_human(display_long)|uniprotkb:Ubiquitin-specific peptidase 48(gene name synonym)|uniprotkb:Ubiquitin-specific protease 48(gene name synonym)|uniprotkb:USP48(gene name)|psi-mi:USP48(display_short)|uniprotkb:USP31(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 48(gene name synonym)|uniprotkb:Deubiquitinating enzyme 48(gene name synonym)|uniprotkb:Ubiquitin thioesterase 48(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001027902.1|refseq:NP_115612.4|refseq:NP_001317323.1|ensembl:ENSG00000090686(gene)|ensembl:ENST00000308271(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028889|interpro:IPR029071|interpro:IPR033841|interpro:IPR035927|interpro:IPR038765|interpro:IPR044743|reactome:R-HSA-5689880 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:isCDJibvxhTQ6G+bIdJ2/vsNSRY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P57678 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356700|uniprotkb:Q9NZS7|uniprotkb:Q9UG32|uniprotkb:Q9Y4Q2|intact:EBI-1058464|ensembl:ENSP00000321706 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:gemi4_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short)|uniprotkb:Component of gems 4(gene name synonym)|uniprotkb:p97(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_056536.2|ensembl:ENSG00000179409(gene)|ensembl:ENST00000319004(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR033265|mint:P57678|reactome:R-HSA-191859 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:PeyFnc2VuUrZrCj8RtkVVS6KQF49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P61247 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352378|uniprotkb:P33443|uniprotkb:P49241|uniprotkb:B2R4D4|intact:EBI-3440915|uniprotkb:D3DP05|ensembl:ENSP00000346050 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs3a_human(display_long)|uniprotkb:RPS3A(gene name)|psi-mi:RPS3A(display_short)|uniprotkb:MFTL(gene name synonym)|uniprotkb:FTE1(gene name synonym)|uniprotkb:v-fos transformation effector protein(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000997.1|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:4V6X|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000145425(gene)|ensembl:ENST00000274065(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001593(Ribosomal protein S3Ae)|interpro:IPR018281|interpro:IPR027500|mint:P61247|rcsb pdb:4UG0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6OM7|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-29408N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:g1TMzz8OFWEuhrRCoecj7KW0qTQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O43143 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62701 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q99623 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:h4pib54mBeQgOKCe/hib58LM26w9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q7L2E3 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1211456|uniprotkb:O94965|uniprotkb:Q7Z753|uniprotkb:Q96CH4|uniprotkb:Q9NUQ0|uniprotkb:A8K5F1|ensembl:ENSP00000392601|ensembl:ENSP00000405620|intact:EBI-21350949 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:dhx30_human(display_long)|uniprotkb:DHX30(gene name)|psi-mi:DHX30(display_short)|uniprotkb:KIAA0890(gene name synonym)|uniprotkb:DDX30(gene name synonym)|uniprotkb:DEAH box protein 30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055781.2|refseq:NP_619520.1|refseq:XP_011531796.1|refseq:XP_011531797.1|refseq:XP_016861406.1|ensembl:ENSG00000132153(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007417"(central nervous system development)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q7L2E3|rcsb pdb:2DB2|ensembl:ENST00000445061(transcript)|ensembl:ENST00000446256(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:tb4GzZKLycraXS0NlVqj8reV3IQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15061 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2563523|uniprotkb:Q92577|uniprotkb:Q15395|ensembl:ENSP00000384302 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:wdr43_human(display_long)|uniprotkb:WDR43(gene name)|psi-mi:WDR43(display_short)|uniprotkb:KIAA0007(gene name synonym)|uniprotkb:UTP5(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 5 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055946.1|ensembl:ENSG00000163811(gene)|ensembl:ENST00000407426(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003711"(transcription elongation regulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q15061|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:5YWzMczifqbhFvvX1HkF3XYW6xA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P84098 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-916524|uniprotkb:P14118|uniprotkb:P22908|uniprotkb:Q502Y6|uniprotkb:Q7Z6E4|uniprotkb:B2R4K2|ensembl:ENSP00000225430 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl19_human(display_long)|uniprotkb:RPL19(gene name)|psi-mi:RPL19(display_short)|uniprotkb:Large ribosomal subunit protein eL19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000972.1|ensembl:ENSG00000108298(gene)|ensembl:ENST00000225430(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970|interpro:IPR039547|mint:P84098|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:sYEwdB8ySbxh3iL0uqlfRRVFiWw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q969X6 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9GZL7 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2490660|uniprotkb:B3KPA9|uniprotkb:Q96HU0|uniprotkb:Q9NV80|uniprotkb:Q9NYI8|ensembl:ENSP00000261015 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:wdr12_human(display_long)|uniprotkb:WDR12(gene name)|psi-mi:WDR12(display_short)|uniprotkb:WD repeat-containing protein 12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0007219"(Notch signaling pathway)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR012972(NLE)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR028599|interpro:IPR036322|mint:Q9GZL7|rcsb pdb:6N31|rcsb pdb:6P0Q|reactome:R-HSA-6791226|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000138442(gene)|ensembl:ENST00000261015(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|refseq:NP_060726.3 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:7qCdIJOJA36eRlrwJA6x0XC/Tqc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P23396 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y314 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1051889|uniprotkb:Q96FD2|ensembl:ENSP00000470034 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nosip_human(display_long)|uniprotkb:eNOS-interacting protein(gene name synonym)|uniprotkb:NOSIP(gene name)|psi-mi:NOSIP(display_short)|uniprotkb:CGI-25(orf name)|uniprotkb:E3 ubiquitin-protein ligase NOSIP(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NOSIP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001257889.1|refseq:NP_057037.1|ensembl:ENSG00000142546(gene)|ensembl:ENST00000596358(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016818(Nitric oxide synthase-interacting)|interpro:IPR031790|reactome:R-HSA-203754|refseq:XP_016882340.1|refseq:XP_016882341.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:vC1sjYkWe4QjRlwCJ3C5+EB8PcA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q6DKI1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1052408|uniprotkb:Q5TFZ5|uniprotkb:Q6PEK3|uniprotkb:A8K7D4|uniprotkb:B7Z652|ensembl:ENSP00000346063|ensembl:ENSP00000418221 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl7l_human(display_long)|uniprotkb:RPL7L1(gene name)|psi-mi:RPL7L1(display_short)|uniprotkb:Large ribosomal subunit protein uL30-like 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_940888.3|ensembl:ENSG00000146223(gene)|ensembl:ENST00000304734(transcript)|ensembl:ENST00000493763(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:Q6DKI1|refseq:XP_016866269.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:hB4ePwPQxahWRS9OEEfq1nL/lk09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96GQ7 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-722051|uniprotkb:A0AVB6|uniprotkb:Q5VXM7|uniprotkb:Q8WYG4|uniprotkb:Q969N7|uniprotkb:Q96F57|uniprotkb:Q96L97|uniprotkb:Q9BWY9|uniprotkb:Q9BXF0|uniprotkb:Q9H990|uniprotkb:Q9NWU3|uniprotkb:Q9P0C2|uniprotkb:Q9UGD6|uniprotkb:B7ZLY1 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx27_human(display_long)|uniprotkb:DEAD box protein 27(gene name synonym)|uniprotkb:DDX27(gene name)|psi-mi:DDX27(display_short)|uniprotkb:RHLP(gene name synonym)|uniprotkb:cPERP-F(gene name synonym)|uniprotkb:HSPC259(orf name)|uniprotkb:PP3241(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 interpro:IPR027417|refseq:NP_060365.7|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|mint:Q96GQ7|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Z4Dm6lxXyqB18+uPxROJszLWYdE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P37108 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-353399|uniprotkb:Q6B0K5|intact:EBI-1053250|uniprotkb:Q96Q14|uniprotkb:B5BUF5|ensembl:ENSP00000267884 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:srp14_human(display_long)|uniprotkb:SRP14(gene name)|psi-mi:SRP14(display_short)|uniprotkb:18 kDa Alu RNA-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_003125.3|dip:DIP-6152N|ensembl:ENSG00000140319(gene)|ensembl:ENST00000267884(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045047"(protein targeting to ER)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|mint:P37108|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYJ|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-6798695 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:0xHelIgJbXaUrFsHGoj1wDQKdPs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H9Y2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-9996007|uniprotkb:Q5VSK7|uniprotkb:Q6AHX1|uniprotkb:Q8WXZ8|ensembl:ENSP00000359688 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rpf1_human(display_long)|uniprotkb:RPF1(gene name)|psi-mi:RPF1(display_short)|uniprotkb:BXDC5(gene name synonym)|uniprotkb:Brix domain-containing protein 5(gene name synonym)|uniprotkb:Ribosome biogenesis protein RPF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_079341.2|ensembl:ENSG00000117133(gene)|ensembl:ENST00000370654(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR044281|go:"GO:0000460"(maturation of 5.8S rRNA) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:lPJHR67nRalKzyv8rBOSx3duAvE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P42224 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q7Z7K6 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1210604|uniprotkb:Q3L8N5|uniprotkb:Q8NFH6|uniprotkb:B2RPK2 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cenpv_human(display_long)|uniprotkb:CENPV(gene name)|psi-mi:CENPV(display_short)|uniprotkb:Nuclear protein p30(gene name synonym)|uniprotkb:PRR6(gene name synonym)|uniprotkb:Proline-rich protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_859067.2|interpro:IPR006913(Glutathione-dependent formaldehyde-activating, GFA)|interpro:IPR011057(Mss4-like)|mint:Q7Z7K6|go:"GO:0000776"(kinetochore)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0030496"(midbody)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0005829"(cytosol) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:q2Dt9PEcUigyqjqFMVm3dxk54B09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q5JTH9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-310743|uniprotkb:Q5JTH8|uniprotkb:Q69YK4|uniprotkb:Q96E87|uniprotkb:Q9BUH3|uniprotkb:Q9Y4C7|intact:EBI-2558452|uniprotkb:B4DK00|uniprotkb:E9PCK7|intact:EBI-28986119|ensembl:ENSP00000360031|ensembl:ENSP00000446184 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rrp12_human(display_long)|uniprotkb:RRP12(gene name)|psi-mi:RRP12(display_short)|uniprotkb:KIAA0690(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001138586.1|refseq:NP_055994.2|refseq:NP_001271266.1|ensembl:ENST00000315563|ensembl:ENSP00000324315|ensembl:ENSP00000360031|ensembl:ENST00000414986|ensembl:ENSP00000414863|ensembl:ENSP00000446184|ensembl:ENSG00000052749(gene)|ensembl:ENST00000370992(transcript)|ensembl:ENST00000536831(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012978(Region of unknown function, NUC173)|interpro:IPR016024(Armadillo-type fold)|mint:Q5JTH9 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:O2Ih3mwXBDMynmqc4UzvizKVnNg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8TDD1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1052503|uniprotkb:Q86YT8|uniprotkb:Q9BRZ1|ensembl:ENSP00000304072 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx54_human(display_long)|uniprotkb:DEAD box protein 54(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001104792.1|refseq:NP_076977.3|ensembl:ENSG00000123064(gene)|ensembl:ENST00000306014(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|mint:Q8TDD1|go:"GO:0003724"(RNA helicase activity) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:VzxEkRaOIND08jGJk3yyoztesjo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P49327 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8IXT5 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-3044077|ensembl:ENSP00000382239|ensembl:ENSP00000427729|ensembl:ENSP00000428269|ensembl:ENSP00000429807|ensembl:ENSP00000430474|uniprotkb:A8MYB5 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rb12b_human(display_long)|uniprotkb:RBM12B(gene name)|psi-mi:RBM12B(display_short)|uniprotkb:RNA-binding motif protein 12B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:XP_016868895.1|refseq:XP_016868896.1|refseq:XP_016868897.1|ensembl:ENSG00000183808(gene)|ensembl:ENST00000399300(transcript)|ensembl:ENST00000517700(transcript)|ensembl:ENST00000518597(transcript)|ensembl:ENST00000519109(transcript)|ensembl:ENST00000520560(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034588|interpro:IPR034858|interpro:IPR035979|refseq:XP_011515329.1|refseq:XP_011515330.1|refseq:XP_011515331.1|refseq:NP_976324.2|refseq:XP_005250972.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:WFJYO2tbSpgVmVVnSyFLn4O2+HM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H0S4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2515241|ensembl:ENSP00000350698|uniprotkb:Q96NV8|uniprotkb:B3KXP4|uniprotkb:Q96GM0|uniprotkb:G5E955|uniprotkb:Q9UI98 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx47_human(display_long)|uniprotkb:DDX47(gene name)|psi-mi:DDX47(display_short)|uniprotkb:DEAD box protein 47(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000213782(gene)|ensembl:ENST00000358007(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044765|mint:Q9H0S4|rcsb pdb:3BER|reactome:R-HSA-6790901|reactome:R-HSA-6791226|interpro:IPR014001(DEAD-like helicase, N-terminal)|refseq:NP_057439.2|refseq:NP_957518.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:AhH5kg/8cw6L5385wUw4PR243rY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P05141 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P05387 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352813|ensembl:ENSP00000322419|ensembl:ENSP00000431240|uniprotkb:Q6FG96 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:Large ribosomal subunit protein P2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000177600(gene)|ensembl:ENST00000321153(transcript)|ensembl:ENST00000530797(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-HSA-156827|reactome:R-HSA-156902|refseq:NP_000995.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q13151 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-724092|ensembl:ENSP00000316042|intact:EBI-1043661|uniprotkb:Q6IB18 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006796.1|ensembl:ENSG00000177733(gene)|ensembl:ENST00000314940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P78527 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P22087 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-358318|uniprotkb:O75259|uniprotkb:Q6IAT5|uniprotkb:Q9UPI6|ensembl:ENSP00000221801|ensembl:ENSP00000487390|uniprotkb:B5BUE8 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:fbrl_human(display_long)|uniprotkb:FBL(gene name)|psi-mi:FBL(display_short)|uniprotkb:FIB1(gene name synonym)|uniprotkb:FLRN(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)|uniprotkb:34 kDa nucleolar scleroderma antigen(gene name synonym)|uniprotkb:U6 snRNA 2'-O-methyltransferase fibrillarin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001427.2|ensembl:ENSG00000105202(gene)|ensembl:ENSG00000280548(gene)|ensembl:ENST00000221801(transcript)|ensembl:ENST00000625241(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0001652"(granular component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|mint:P22087|rcsb pdb:2IPX|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-27569N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:8m8FDRSxGNKNXpJMcWWbcHL3uss9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P32969 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-358122|ensembl:ENSP00000346022|ensembl:ENSP00000400467|ensembl:ENSP00000494697 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl9_human(display_long)|uniprotkb:RPL9(gene name)|psi-mi:RPL9(display_short)|uniprotkb:RPL9P7(gene name)|psi-mi:RPL9P7(display_short)|uniprotkb:RPL9P8(gene name)|psi-mi:RPL9P8(display_short)|uniprotkb:RPL9P9(gene name)|psi-mi:RPL9P9(display_short)|uniprotkb:Large ribosomal subunit protein uL6(gene name synonym)|uniprotkb:OK/SW-cl.103(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000652.2|refseq:NP_001020092.1|ensembl:ENSG00000163682(gene)|ensembl:ENST00000295955(transcript)|ensembl:ENST00000449470(transcript)|ensembl:ENST00000645496(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789|mint:P32969|rcsb pdb:2CQL|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:v0thFydYo0aEqBblJoqQX8b7JCA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O14981 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1043840|uniprotkb:O43578|ensembl:ENSP00000265990|uniprotkb:B4E0W6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:btaf1_human(display_long)|uniprotkb:BTAF1(gene name)|psi-mi:BTAF1(display_short)|uniprotkb:TAF172(gene name synonym)|uniprotkb:ATP-dependent helicase BTAF1(gene name synonym)|uniprotkb:TBP-associated factor 172(gene name synonym)|uniprotkb:"TAF(II)170"(gene name synonym)|uniprotkb:B-TFIID transcription factor-associated 170 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_003963.1|ensembl:ENSG00000095564(gene)|ensembl:ENST00000265990(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022707|interpro:IPR027417|interpro:IPR038718|interpro:IPR044078|mint:O14981 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:TUDUowqheA9/EO9RjuCwgwa6HY49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96P70 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NR12 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-350517|uniprotkb:Q14250|uniprotkb:Q5XG82|uniprotkb:Q6NVZ5|uniprotkb:Q96C91|uniprotkb:Q9BXB8|uniprotkb:Q9BXB9|intact:EBI-2556830|ensembl:ENSP00000348099 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pdli7_human(display_long)|uniprotkb:LIM mineralization protein(gene name synonym)|uniprotkb:Protein enigma(gene name synonym)|uniprotkb:PDLIM7(gene name)|psi-mi:PDLIM7(display_short)|uniprotkb:ENIGMA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_976227.1|refseq:NP_998801.1|refseq:NP_005442.2|ensembl:ENST00000355572|ensembl:ENSP00000347776|ensembl:ENSP00000348099|ensembl:ENST00000359895|ensembl:ENSP00000352964|ensembl:ENST00000393551|ensembl:ENSP00000377182|ensembl:ENST00000486828|ensembl:ENSP00000439157|ensembl:ENST00000493815|ensembl:ENSP00000431236|ensembl:ENSG00000196923(gene)|ensembl:ENST00000355841(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031941"(filamentous actin)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036034|rcsb pdb:2Q3G|reactome:R-HSA-8853659 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:XBVF0Y1DFqIYbnt/e/rYqS/m4d09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O43683 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-748936|uniprotkb:O43430|uniprotkb:O43643|uniprotkb:O60626|uniprotkb:Q53QE4|intact:EBI-10974242|uniprotkb:E9PC26|uniprotkb:F5GXI5|intact:EBI-28974347|ensembl:ENSP00000302530 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:bub1_human(display_long)|uniprotkb:BUB1A(gene name synonym)|uniprotkb:BUB1(gene name)|psi-mi:BUB1(display_short)|uniprotkb:BUB1L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSP00000302530|ensembl:ENST00000409311|ensembl:ENSP00000386701|ensembl:ENST00000535254|ensembl:ENSP00000441013|refseq:NP_004327.1|refseq:NP_001265546.1|ensembl:ENSG00000169679(gene)|ensembl:ENST00000302759(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007063"(regulation of sister chromatid cohesion)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O43683|rcsb pdb:2LAH|rcsb pdb:4A1G|rcsb pdb:4QPM|rcsb pdb:4R8Q|rcsb pdb:5DMZ|rcsb pdb:6F7B|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-24206N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:hsbJZRz5kXxVI+ADgSaCoUfXE1o9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q92621 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O60287 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1762349|uniprotkb:D3DSE5|uniprotkb:Q96NX1|uniprotkb:Q9NYQ1|ensembl:ENSP00000372199 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:npa1p_human(display_long)|uniprotkb:URB1(gene name)|psi-mi:URB1(display_short)|uniprotkb:C21orf108(gene name synonym)|uniprotkb:KIAA0539(gene name synonym)|uniprotkb:NPA1(gene name synonym)|uniprotkb:URB1 ribosome biogenesis 1 homolog(gene name synonym)|uniprotkb:NOP254(gene name synonym)|uniprotkb:Nucleolar protein 254 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055640.2|interpro:IPR021714|interpro:IPR032436|interpro:IPR039844|ensembl:ENSG00000142207(gene)|ensembl:ENST00000382751(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|interpro:IPR016024(Armadillo-type fold) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:tolq2rVG0N5qy3qGiIkPj8xtVis9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15233 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O14980 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H583 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1048716|uniprotkb:Q5T3Q8|uniprotkb:Q6P197|uniprotkb:Q9NW23|ensembl:ENSP00000355541 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:heat1_human(display_long)|uniprotkb:Protein BAP28(gene name synonym)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)|uniprotkb:BAP28(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 10 homolog(gene name synonym)|uniprotkb:UTP10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060542.4|ensembl:ENSG00000119285(gene)|ensembl:ENST00000366582(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022125|interpro:IPR040191|mint:Q9H583|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:0WoP84UUVfXWppmvCYa/n5GTzc89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NV31 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-747481|uniprotkb:Q53G10|uniprotkb:B3KQ67|ensembl:ENSP00000326981|ensembl:ENSP00000385217 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:imp3_human(display_long)|uniprotkb:BRMS2(gene name synonym)|uniprotkb:IMP3(gene name)|psi-mi:IMP3(display_short)|uniprotkb:C15orf12(gene name synonym)|uniprotkb:MRPS4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060755.1|go:"GO:0030684"(preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR022801|interpro:IPR036986|mint:Q9NV31|rcsb pdb:2CQJ|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0030515"(snoRNA binding)|ensembl:ENSG00000177971(gene)|ensembl:ENST00000314852(transcript)|ensembl:ENST00000403490(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:7tf5HEal59lCqBIvQaFLksqchAw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14146 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-9996029|uniprotkb:Q5VYC9|ensembl:ENSP00000258243 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:urb2_human(display_long)|uniprotkb:URB2(gene name)|psi-mi:URB2(display_short)|uniprotkb:KIAA0133(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055592.2|refseq:NP_001300950.1|ensembl:ENSG00000135763(gene)|ensembl:ENST00000258243(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0016235"(aggresome)|go:"GO:0030496"(midbody)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR018849 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:BhDO5U3/iVSj0xlncOQpkGRl+gc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P38432 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q02241 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P78346 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-366553|uniprotkb:B2R799|uniprotkb:E9PB02|ensembl:ENSP00000360768 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rpp30_human(display_long)|uniprotkb:RPP30(gene name)|psi-mi:RPP30(display_short)|uniprotkb:RNASEP2(gene name synonym)|uniprotkb:RNase P subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001098016.1|refseq:NP_006404.1|refseq:XP_011537422.1|refseq:XP_011537423.1|ensembl:ENSG00000148688(gene)|ensembl:ENST00000371703(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002738(RNase P subunit p30)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P78346|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_016870964.1|refseq:XP_016870966.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:pRHvUnpzpNHGzYbS+kRiSa0m71E9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62249 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352480|uniprotkb:P17008|uniprotkb:B2RDD5|ensembl:ENSP00000251453 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs16_human(display_long)|uniprotkb:RPS16(gene name)|psi-mi:RPS16(display_short)|uniprotkb:Small ribosomal subunit protein uS9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001011.1|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000105193(gene)|ensembl:ENST00000251453(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P62249|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|dip:DIP-33200N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:OrKriR6HsATLaO+drdUa2w3Gpd09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P46782 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-350569|uniprotkb:Q96BN0|uniprotkb:B2R4T2|ensembl:ENSP00000196551|ensembl:ENSP00000470114|ensembl:ENSP00000472985 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs5_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short)|uniprotkb:Small ribosomal subunit protein uS7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001000.2|rcsb pdb:6OLZ|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Z6M|rcsb pdb:6XA1|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6Y0G|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:5FLX|rcsb pdb:6OLG|rcsb pdb:6OLI|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|ensembl:ENSG00000083845(gene)|ensembl:ENST00000196551(transcript)|ensembl:ENST00000596046(transcript)|ensembl:ENST00000601521(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823|mint:P46782|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5AJ0|reactome:R-HSA-72702 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:SoCJdf2InngZZtlz5qD1k5CEfEo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P11940 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14692 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2513630|ensembl:ENSP00000363642|uniprotkb:Q86XJ9|uniprotkb:Q5QPT5 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:bms1_human(display_long)|uniprotkb:BMS1(gene name)|psi-mi:BMS1(display_short)|uniprotkb:BMS1L(gene name synonym)|uniprotkb:KIAA0187(gene name synonym)|uniprotkb:Ribosome assembly protein BMS1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000165733(gene)|ensembl:ENST00000374518(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0030686"(90S preribosome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR027417|interpro:IPR030387|interpro:IPR037875|interpro:IPR039761|mint:Q14692|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0005730"(nucleolus)|refseq:XP_011538704.1|refseq:NP_055568.3|refseq:XP_005271903.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:9sd7sK6/Ue4DgLRT+j9Iw0+8om09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8TC12 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2823756|uniprotkb:Q0QD40|uniprotkb:B4DDW0|uniprotkb:A8K062|uniprotkb:B2RB26|uniprotkb:A6NDK3|uniprotkb:Q6IAH5|uniprotkb:Q9NRW0|uniprotkb:Q9Y391|ensembl:ENSP00000370750 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rdh11_human(display_long)|uniprotkb:RDH11(gene name)|psi-mi:RDH11(display_short)|uniprotkb:ARSDR1(gene name synonym)|uniprotkb:PSDR1(gene name synonym)|uniprotkb:Androgen-regulated short-chain dehydrogenase/reductase 1(gene name synonym)|uniprotkb:HCV core-binding protein HCBP12(gene name synonym)|uniprotkb:Prostate short-chain dehydrogenase/reductase 1(gene name synonym)|uniprotkb:Retinal reductase 1(gene name synonym)|uniprotkb:SDR7C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 7C member 1(gene name synonym)|uniprotkb:CGI-82(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0110095"(cellular detoxification of aldehyde)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|mint:Q8TC12|reactome:R-HSA-2453902|reactome:R-HSA-5365859|reactome:R-HSA-975634|refseq:NP_057110.3|refseq:NP_001239579.1|ensembl:ENSG00000072042(gene)|ensembl:ENST00000381346(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0004745"(NAD-retinol dehydrogenase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|go:"GO:0102354"(11-cis-retinol dehydrogenase activity) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:elUutgO+T5gnwthTzc4WDetnuug9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UMY1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2862609|uniprotkb:Q9Y3U7|uniprotkb:Q5T297|ensembl:ENSP00000405674 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nol7_human(display_long)|uniprotkb:NOL7(gene name)|psi-mi:NOL7(display_short)|uniprotkb:C6orf90(gene name synonym)|uniprotkb:NOP27(gene name synonym)|uniprotkb:Nucleolar protein of 27 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_057251.2|refseq:NP_001304653.1|ensembl:ENSG00000225921(gene)|ensembl:ENST00000451315(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|interpro:IPR012579(NUC129)|interpro:IPR039626|mint:Q9UMY1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:4I1C2wd0qGg9CWZDodm/Bp+tptA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H0A0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-876527|ensembl:ENSP00000257829|uniprotkb:B4DFD5|uniprotkb:E7ESU4|uniprotkb:E9PMN9|uniprotkb:Q86WK5|uniprotkb:Q9C0F4|uniprotkb:Q9HA61|uniprotkb:Q9NVF2 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nat10_human(display_long)|uniprotkb:NAT10(gene name)|psi-mi:NAT10(display_short)|uniprotkb:KIAA1709(gene name synonym)|uniprotkb:ALP(gene name synonym)|uniprotkb:18S rRNA cytosine acetyltransferase(gene name synonym)|uniprotkb:N-acetyltransferase 10(gene name synonym)|uniprotkb:N-acetyltransferase-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000135372(gene)|ensembl:ENST00000257829(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000154"(rRNA modification)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051391"(tRNA acetylation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0106162"(mRNA N-acetyltransferase activity)|go:"GO:1904812"(rRNA acetylation involved in maturation of SSU-rRNA)|go:"GO:1990883"(rRNA cytidine N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR007807(Protein of unknown function DUF699, ATPase putative)|interpro:IPR013562(Region of unknown function DUF1726)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR027992|interpro:IPR032672|interpro:IPR033688|mint:Q9H0A0|rcsb pdb:6VLA|reactome:R-HSA-6790901|refseq:NP_001137502.1|refseq:NP_078938.2 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:3eWpscghkRC8Km7mBsUQqjhCKVs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P53621 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P06493 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-444308|ensembl:ENSP00000378699|uniprotkb:O60764|uniprotkb:C9J497|uniprotkb:A8K7C4 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cdk1_human(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0007569"(cell aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014038"(regulation of Schwann cell differentiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035173"(histone kinase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0048678"(response to axon injury)|go:"GO:0051301"(cell division)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0042493"|go:"GO:0072686"(mitotic spindle)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P06493|rcsb pdb:1LC9|rcsb pdb:4Y72|rcsb pdb:4YC3|rcsb pdb:4YC6|rcsb pdb:5HQ0|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|rcsb pdb:6GU6|go:"GO:0042752"(regulation of circadian rhythm)|rcsb pdb:6GU7|rcsb pdb:6TWN|reactome:R-HSA-110056|reactome:R-HSA-113507|reactome:R-HSA-1362300|reactome:R-HSA-162658|reactome:R-HSA-170145|reactome:R-HSA-174048|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-4419969|reactome:R-HSA-5620912|reactome:R-HSA-5687128|reactome:R-HSA-5689896|reactome:R-HSA-6804114|reactome:R-HSA-6804757|reactome:R-HSA-68875|reactome:R-HSA-69205|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8878166|ensembl:ENSG00000170312(gene)|ensembl:ENST00000395284(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|refseq:NP_001777.1|refseq:NP_203698.1|refseq:XP_005270360.1|refseq:NP_001307847.1|dip:DIP-35N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O60762 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:znbNDwp7t238ByanlbQzsTMvwTY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P68363 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P46781 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-351206|uniprotkb:Q4QRK7|uniprotkb:Q9BVZ0|ensembl:ENSP00000302896|ensembl:ENSP00000375632|ensembl:ENSP00000375633|ensembl:ENSP00000478449|ensembl:ENSP00000479917|ensembl:ENSP00000480135|ensembl:ENSP00000480662|ensembl:ENSP00000481194|ensembl:ENSP00000481553|ensembl:ENSP00000481655|ensembl:ENSP00000481764|ensembl:ENSP00000481822|ensembl:ENSP00000482023|ensembl:ENSP00000482274|ensembl:ENSP00000482338|ensembl:ENSP00000482475|ensembl:ENSP00000483179|ensembl:ENSP00000484394|uniprotkb:A9C4C1 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs9_human(display_long)|uniprotkb:RPS9(gene name)|psi-mi:RPS9(display_short)|uniprotkb:Small ribosomal subunit protein uS4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001004.2|refseq:NP_001308630.1|refseq:NP_001308631.1|refseq:NP_001308633.1|ensembl:ENSG00000170889(gene)|ensembl:ENSG00000274005(gene)|ensembl:ENSG00000274626(gene)|ensembl:ENSG00000274646(gene)|ensembl:ENSG00000274950(gene)|ensembl:ENSG00000275323(gene)|ensembl:ENSG00000277079(gene)|ensembl:ENSG00000277359(gene)|ensembl:ENSG00000278081(gene)|ensembl:ENSG00000278270(gene)|ensembl:ENST00000302907(transcript)|ensembl:ENST00000391752(transcript)|ensembl:ENST00000391753(transcript)|ensembl:ENST00000610826(transcript)|ensembl:ENST00000610953(transcript)|ensembl:ENST00000611921(transcript)|ensembl:ENST00000614737(transcript)|ensembl:ENST00000615346(transcript)|ensembl:ENST00000616082(transcript)|ensembl:ENST00000616536(transcript)|ensembl:ENST00000616839(transcript)|ensembl:ENST00000616877(transcript)|ensembl:ENST00000616928(transcript)|ensembl:ENST00000617291(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000618751(transcript)|go:"GO:0005829"(cytosol)|ensembl:ENST00000619229(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|ensembl:ENST00000620720(transcript)|ensembl:ENST00000620940(transcript)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR018079|interpro:IPR022801|interpro:IPR036986|mint:P46781|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|go:"GO:0005634"(nucleus)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|go:"GO:0005654"(nucleoplasm)|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:PGNjkKMs8bMMOSOz2AQvwuCvO1A9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P46063 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2823728|uniprotkb:A8K6G2|ensembl:ENSP00000395449|ensembl:ENSP00000416739 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:recq1_human(display_long)|uniprotkb:RECQL(gene name)|psi-mi:RECQL(display_short)|uniprotkb:RECQ1(gene name synonym)|uniprotkb:RECQL1(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 1(gene name synonym)|uniprotkb:DNA-dependent ATPase Q1(gene name synonym)|uniprotkb:RecQ protein-like 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_002898.2|refseq:NP_116559.1|ensembl:ENSG00000004700(gene)|ensembl:ENST00000421138(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0016020"(membrane)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|mint:P46063|rcsb pdb:2V1X|rcsb pdb:2WWY|rcsb pdb:4U7D|rcsb pdb:6JTZ|ensembl:ENST00000444129(transcript)|refseq:XP_005253518.1|refseq:XP_005253519.1|refseq:XP_005253520.1|refseq:XP_005253521.1|dip:DIP-29216N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:zJXPLIWtbjvhAhWH0HN+qdkCCOg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9HCD5 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2863498|uniprotkb:Q9H1F2|uniprotkb:Q6HA99|uniprotkb:Q9H2T2|uniprotkb:B2RTV9|uniprotkb:Q9H4Y9|uniprotkb:E1P5R0|ensembl:ENSP00000290231 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ncoa5_human(display_long)|uniprotkb:NCOA5(gene name)|psi-mi:NCOA5(display_short)|uniprotkb:KIAA1637(gene name synonym)|uniprotkb:Coactivator independent of AF-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_066018.1|ensembl:ENSG00000124160(gene)|ensembl:ENST00000290231(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR036621|mint:Q9HCD5|rcsb pdb:1V95|rcsb pdb:2J7X|rcsb pdb:2J7Y|rcsb pdb:4ZI1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:OxiZZWrvRqepYlZiuTR4RqZWn1A9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UI30 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-373326|uniprotkb:Q3MHC7|uniprotkb:Q8N2Z4|uniprotkb:B2R539|uniprotkb:J3KNG5|ensembl:ENSP00000438349 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tr112_human(display_long)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym)|uniprotkb:AD-001(orf name)|uniprotkb:HSPC152(orf name)|uniprotkb:HSPC170(orf name)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001273011.1|refseq:NP_057488.1|ensembl:ENSG00000173113(gene)|ensembl:ENST00000544844(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070476"("rRNA (guanine-N7)-methylation")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR005651(Protein of unknown function DUF343)|mint:Q9UI30|rcsb pdb:6G4W|rcsb pdb:6H1D|rcsb pdb:6H1E|rcsb pdb:6H2U|rcsb pdb:6H2V|rcsb pdb:6K0X|rcsb pdb:6KHS|rcsb pdb:6KMR|rcsb pdb:6KMS|rcsb pdb:6PED|reactome:R-HSA-156581|reactome:R-HSA-6782315|reactome:R-HSA-6790901|reactome:R-HSA-72764|interpro:IPR039127 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:N3kvBRpRMFAeB5AYgOmAvs34u+c9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q7Z2W4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_064504.2|refseq:NP_078901.3|ensembl:ENSG00000105939(gene)|ensembl:ENST00000242351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|reactome:R-HSA-6802952|dip:DIP-37896N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UHD8 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-851542|uniprotkb:Q96QF3|uniprotkb:Q96QF4|uniprotkb:Q96QF5|uniprotkb:Q9HA04|uniprotkb:Q9UG40|uniprotkb:Q9Y5W4|uniprotkb:A8K2V3|uniprotkb:B3KPM0|uniprotkb:B4DTL9|uniprotkb:B4E0N2|uniprotkb:B4E274|uniprotkb:B7Z654|ensembl:ENSP00000391249 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:sept9_human(display_long)|uniprotkb:SEPTIN9(gene name)|psi-mi:SEPTIN9(display_short)|uniprotkb:KIAA0991(gene name synonym)|uniprotkb:MLL septin-like fusion protein MSF-A(gene name synonym)|uniprotkb:MSF(gene name synonym)|uniprotkb:Ovarian/Breast septin(gene name synonym)|uniprotkb:SEPT9(gene name synonym)|uniprotkb:Septin D1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:XP_006721706.1|refseq:XP_006721707.1|refseq:NP_001106963.1|refseq:NP_001106964.1|refseq:NP_001106965.1|refseq:NP_001106966.1|refseq:NP_001106967.1|refseq:NP_001106968.1|refseq:NP_006631.2|refseq:XP_016879520.1|refseq:XP_016879521.1|refseq:NP_001280624.1|refseq:NP_001280625.1|refseq:NP_001280626.1|refseq:NP_001280627.1|refseq:XP_011522509.1|refseq:XP_011522510.1|refseq:XP_005257019.1|dip:DIP-36697N|ensembl:ENSG00000184640(gene)|ensembl:ENST00000427177(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030645|mint:Q9UHD8|rcsb pdb:4YQF|rcsb pdb:5CYO|rcsb pdb:5CYP - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:YzUn6hS5tAX/U+SJ8YzqzWW/dQI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P63167 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96PV6 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|intact:EBI-28984630|ensembl:ENSP00000318374|ensembl:ENSP00000478337|ensembl:ENSP00000478975|ensembl:ENSP00000480663|uniprotkb:A0A087WTE7 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_443157.1|ensembl:ENSG00000167615(gene)|ensembl:ENSG00000274305(gene)|ensembl:ENSG00000276458(gene)|ensembl:ENSG00000276681(gene)|ensembl:ENST00000326764(transcript)|ensembl:ENST00000617180(transcript)|ensembl:ENST00000621306(transcript)|ensembl:ENST00000622672(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|mint:Q96PV6|ensembl:ENSP00000318374|ensembl:ENST00000610314|ensembl:ENSP00000484494|ensembl:ENST00000611866|ensembl:ENSP00000479293|ensembl:ENST00000616932|ensembl:ENSP00000477813|ensembl:ENSP00000480663|ensembl:ENST00000617420|ensembl:ENSP00000481040|ensembl:ENSP00000478337|ensembl:ENSP00000478975|refseq:XP_011524717.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:kwgKuV5NW0hITukndsYeyQHTdd09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P06748 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15050 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-749186|uniprotkb:Q9BUX8|ensembl:ENSP00000322396 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rrs1_human(display_long)|uniprotkb:RRS1(gene name)|psi-mi:RRS1(display_short)|uniprotkb:KIAA0112(gene name synonym)|uniprotkb:RRR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055984.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007023(Ribosomal biogenesis regulatory protein)|mint:Q15050|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000179041(gene)|ensembl:ENST00000320270(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:0Nm9UoIGLBiqOGl0E2BA0S5EXIU9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9GZR7 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-713081|ensembl:ENSP00000481495|ensembl:ENSP00000482106|uniprotkb:E7EMJ4|uniprotkb:Q4V9L5 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx24_human(display_long)|uniprotkb:DEAD box protein 24(gene name synonym)|uniprotkb:DDX24(gene name)|psi-mi:DDX24(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000089737(gene)|ensembl:ENSG00000273761(gene)|ensembl:ENST00000613280(transcript)|ensembl:ENST00000621632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR027417|mint:Q9GZR7|refseq:NP_065147.1|dip:DIP-47301N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:n9gQabTC50Y/LtGMAMFNVgj12as9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62753 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:beDuXCIqL99V9JlVfpzx7MdpH689606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O00566 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-5235884|uniprotkb:A0AVJ8|ensembl:ENSP00000244230 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mpp10_human(display_long)|uniprotkb:MPHOSPH10(gene name)|psi-mi:MPHOSPH10(display_short)|uniprotkb:MPP10(gene name synonym)|uniprotkb:M phase phosphoprotein 10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005782.1|ensembl:ENSG00000124383(gene)|ensembl:ENST00000244230(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|interpro:IPR012173(U3 small nucleolar ribonucleoprotein complex, subunit Mpp10p)|mint:O00566|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:xkz11U1x5r2joVtVq6JG4asO1Qw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P45880 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354022|ensembl:ENSP00000361686|ensembl:ENSP00000443092|uniprotkb:Q5VWK1|uniprotkb:Q5VWK3|uniprotkb:Q6IB40|uniprotkb:Q7L3J5|uniprotkb:Q9BWK8|uniprotkb:Q9Y5I6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:vdac2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000165637(gene)|ensembl:ENST00000332211(transcript)|ensembl:ENST00000543351(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|refseq:NP_001171712.1|refseq:NP_001171752.1|refseq:NP_003366.2|refseq:NP_001311017.1|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:P45880|reactome:R-HSA-5689880|reactome:R-HSA-8949215 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:seQxCd19Z2HmpXcwb48osAuuafA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P55769 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-712228|ensembl:ENSP00000215956|ensembl:ENSP00000383949|ensembl:ENSP00000497142 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nh2l1_human(display_long)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:High mobility group-like nuclear protein 2 homolog 1(gene name synonym)|uniprotkb:NHP2L1(gene name synonym)|uniprotkb:OTK27(gene name synonym)|uniprotkb:SNU13 homolog(gene name synonym)|uniprotkb:U4/U6.U5 small nuclear ribonucleoprotein SNU13(gene name synonym)|uniprotkb:U4/U6.U5 tri-snRNP 15.5 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000100138(gene)|ensembl:ENST00000215956(transcript)|ensembl:ENST00000401959(transcript)|ensembl:ENST00000648674(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005690"(U4atac snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0007338"(single fertilization)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0051117"(ATPase binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P55769|rcsb pdb:1E7K|rcsb pdb:2JNB|rcsb pdb:2OZB|rcsb pdb:3JCR|rcsb pdb:3SIU|rcsb pdb:3SIV|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_001003796.1|refseq:NP_004999.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:ZMkqsDfMCrTlT/kJxillOA8839E9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P61254 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352405|uniprotkb:Q02877|uniprotkb:Q6IPY2|uniprotkb:B2R4F0|uniprotkb:D3DTR8|ensembl:ENSP00000462322|ensembl:ENSP00000463470|ensembl:ENSP00000463784|ensembl:ENSP00000498177 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl26_human(display_long)|uniprotkb:RPL26(gene name)|psi-mi:RPL26(display_short)|uniprotkb:Large ribosomal subunit protein uL24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000978.1|refseq:NP_001302459.1|refseq:NP_001302460.1|ensembl:ENST00000582556(transcript)|ensembl:ENST00000583011(transcript)|ensembl:ENST00000584164(transcript)|ensembl:ENST00000648839(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|ensembl:ENSG00000161970(gene)|go:"GO:0022626"(cytosolic ribosome)|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904803"(regulation of translation involved in cellular response to UV)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:P61254|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|go:"GO:0034644"(cellular response to UV)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:5LKS|reactome:R-HSA-156827|dip:DIP-33198N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:VAROWOFmYvolVgc/e5E1jAmNuaY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q03701 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1046778|uniprotkb:Q8NE75|ensembl:ENSP00000234170 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cebpz_human(display_long)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:CEBPZ(gene name)|psi-mi:CEBPZ(display_short)|uniprotkb:CBF2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005751.2|ensembl:ENSG00000115816(gene)|ensembl:ENST00000234170(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|mint:Q03701 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:4VX4KR6JGLaEMorRYbfPRaMgGuE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P17844 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y221 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-749003|uniprotkb:Q9NZZ0|uniprotkb:B2RD04|ensembl:ENSP00000254940 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nip7_human(display_long)|uniprotkb:KD93(gene name synonym)|uniprotkb:NIP7(gene name)|psi-mi:NIP7(display_short)|uniprotkb:Nucleolar pre-rRNA processing protein NIP7(gene name synonym)|uniprotkb:CGI-37(orf name)|uniprotkb:HSPC031(orf name)|uniprotkb:HSPC180(orf name)|uniprotkb:OK/SW-cl.76(orf name)|uniprotkb:OK/SW-cl.78(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001186363.1|refseq:NP_057185.1|ensembl:ENSG00000132603(gene)|ensembl:ENST00000254940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR002478(PUA)|interpro:IPR005155(Ribosome biogenesis factor NIP7-like)|interpro:IPR015947(PUA-like)|interpro:IPR016686(Ribosome biogenesis factor, NIP7)|interpro:IPR036974|interpro:IPR040598|mint:Q9Y221|rcsb pdb:1SQW|rcsb pdb:1T5Y|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:912ZyupB0CxH5w23chPh3IIICmY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q92945 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1049099|uniprotkb:O00301|uniprotkb:Q59EZ9|uniprotkb:Q5U4P6|uniprotkb:Q9UNT5|uniprotkb:Q9UQH5|intact:EBI-5455671|ensembl:ENSP00000381216 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:fubp2_human(display_long)|uniprotkb:KH type-splicing regulatory protein(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:KHSRP(gene name)|psi-mi:KHSRP(display_short)|uniprotkb:FUBP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_003676.2|ensembl:ENSG00000088247(gene)|ensembl:ENST00000398148(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0051028"(mRNA transport)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q92945|rcsb pdb:2HH2|rcsb pdb:2HH3|rcsb pdb:2JVZ|rcsb pdb:2OPU|rcsb pdb:2OPV|rcsb pdb:4B8T|reactome:R-HSA-380994|reactome:R-HSA-450604|dip:DIP-48484N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:hlybJllTqSgPgtwwz3kc12zDYh49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P83731 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-353146|ensembl:ENSP00000377640|uniprotkb:P38663|uniprotkb:Q6IBS3|uniprotkb:B2R4Y3 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl24_human(display_long)|uniprotkb:RPL24(gene name)|psi-mi:RPL24(display_short)|uniprotkb:60S ribosomal protein L30(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0016020"(membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:P83731|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZMI|rcsb pdb:6ZME|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000114391(gene)|ensembl:ENST00000394077(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0010458"(exit from mitosis)|refseq:NP_000977.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:+Ah+YGgcjqOsk5ZS1HZUMQA/Of89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NVI1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H4L4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2880236|ensembl:ENSP00000314029|ensembl:ENSP00000403712|uniprotkb:Q96PS4|uniprotkb:Q66K15|uniprotkb:Q86VS7|uniprotkb:Q9Y3W9 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:senp3_human(display_long)|uniprotkb:SENP3(gene name)|psi-mi:SENP3(display_short)|uniprotkb:SSP3(gene name synonym)|uniprotkb:SUSP3(gene name synonym)|uniprotkb:SUMO-1-specific protease 3(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000161956(gene)|ensembl:ENST00000321337(transcript)|ensembl:ENST00000429205(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR037945|interpro:IPR038765|mint:Q9H4L4|reactome:R-HSA-6791226|refseq:NP_056485.2|dip:DIP-47511N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:sE4k87ORoxSjBkbccPsXLYzuqII9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H6R4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2514288|ensembl:ENSP00000297990|uniprotkb:Q5T5M4|uniprotkb:Q8TEZ0|uniprotkb:Q8TEZ1|uniprotkb:Q8TEY9|uniprotkb:Q7L4G6|uniprotkb:Q5T5M3|uniprotkb:Q8N6I0|uniprotkb:Q9H675 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nol6_human(display_long)|uniprotkb:NOL6(gene name)|psi-mi:NOL6(display_short)|uniprotkb:Nucleolar RNA-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000165271(gene)|ensembl:ENST00000297990(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|interpro:IPR005554(Nrap protein)|interpro:IPR035082|interpro:IPR035367|interpro:IPR035368|interpro:IPR035369|interpro:IPR035370|interpro:IPR035371|mint:Q9H6R4|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_075068.2|refseq:NP_631981.2 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:e1Waxlhmq+KTKwHTV13aWEpVF4k9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q08945 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-353771|uniprotkb:Q5BJG8|ensembl:ENSP00000278412 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ssrp1_human(display_long)|uniprotkb:SSRP1(gene name)|psi-mi:SSRP1(display_short)|uniprotkb:FACT80(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SSRP1(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex 80 kDa subunit(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 80 kDa subunit(gene name synonym)|uniprotkb:Structure-specific recognition protein 1(gene name synonym)|uniprotkb:Recombination signal sequence recognition protein 1(gene name synonym)|uniprotkb:T160(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_003137.1|ensembl:ENSG00000149136(gene)|ensembl:ENST00000278412(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035101"(FACT complex)|go:"GO:0042393"(histone binding)|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR036910|interpro:IPR038167|mint:Q08945|rcsb pdb:4IFS|rcsb pdb:5UMR|rcsb pdb:5UMS|rcsb pdb:5VWE|rcsb pdb:6L1E|rcsb pdb:6L1R|rcsb pdb:6L34|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|dip:DIP-169N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:WmdGVZadHdcS6Nk9SI41xKm+OrU9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O00148 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P36873 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356283|ensembl:ENSP00000335084 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y3B9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1055610|intact:EBI-28979625|ensembl:ENSP00000355899 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rrp15_human(display_long)|uniprotkb:Ribosomal RNA-processing protein 15(gene name synonym)|uniprotkb:RRP15(gene name)|psi-mi:RRP15(display_short)|uniprotkb:KIAA0507(gene name synonym)|uniprotkb:CGI-115(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSP00000355899|refseq:NP_057136.2|ensembl:ENSG00000067533(gene)|ensembl:ENST00000366932(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR012459(Protein of unknown function DUF1665) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:EJQFG76HKEYeJ6LwFd5zaUmoScw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P46778 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-350634|uniprotkb:Q16699|ensembl:ENSP00000346027|ensembl:ENSP00000351021|ensembl:ENSP00000370569|ensembl:ENSP00000370574 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl21_human(display_long)|uniprotkb:RPL21(gene name)|psi-mi:RPL21(display_short)|uniprotkb:Large ribosomal subunit protein eL21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 rcsb pdb:6LU8|refseq:NP_000973.2|ensembl:ENSG00000122026(gene)|ensembl:ENST00000272274(transcript)|ensembl:ENST00000311549(transcript)|ensembl:ENST00000319826(transcript)|ensembl:ENST00000326092(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001147(Ribosomal protein L21e)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018259|interpro:IPR036948|mint:P46778|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6OLE|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:UCth+WL9Oj1Y9I5m4i/9X0a5WHk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O15226 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-766011|uniprotkb:Q4VC41|uniprotkb:Q9UJ91|uniprotkb:G3V1N1|ensembl:ENSP00000304803 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nkrf_human(display_long)|uniprotkb:Transcription factor NRF(gene name synonym)|uniprotkb:Protein ITBA4(gene name synonym)|uniprotkb:NKRF(gene name)|psi-mi:NKRF(display_short)|uniprotkb:ITBA4(gene name synonym)|uniprotkb:NRF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001166958.1|refseq:NP_001166959.1|refseq:NP_060014.2|refseq:XP_011529667.1|dip:DIP-34570N|ensembl:ENSG00000186416(gene)|ensembl:ENST00000304449(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000467(D111/G-patch)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036867|mint:O15226|rcsb pdb:6SH6|rcsb pdb:6SH7|interpro:IPR034071 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:jH7qlOvuAHKsjuOyzDpBonpgtF09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15366 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P12235 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H9L3 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-751335|uniprotkb:Q64KA2|uniprotkb:D3DVC6|ensembl:ENSP00000323424|ensembl:ENSP00000357202 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:i20l2_human(display_long)|uniprotkb:ISG20L2(gene name)|psi-mi:ISG20L2(display_short)|uniprotkb:HSD38(orf name)|uniprotkb:HSD-38(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001290024.1|refseq:XP_005245573.1|refseq:XP_006711623.1|refseq:XP_006711624.1|reactome:R-HSA-6791226|interpro:IPR037433|mint:Q9H9L3|ensembl:ENSG00000143319(gene)|ensembl:ENST00000313146(transcript)|ensembl:ENST00000368219(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR034933|interpro:IPR036397 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:i/TZBz8UuJIRm7WZZKjHYU75AS89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q08J23 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1642839|intact:EBI-2839052|uniprotkb:A8K529|uniprotkb:B3KP09|uniprotkb:G3V1R4|uniprotkb:Q9BVN4|uniprotkb:Q9H858|uniprotkb:Q9NXD9|uniprotkb:B2RNR4|intact:EBI-2556652|uniprotkb:B4DQW2|ensembl:ENSP00000264670 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nsun2_human(display_long)|uniprotkb:NSUN2(gene name)|psi-mi:NSUN2(display_short)|uniprotkb:SAKI(gene name synonym)|uniprotkb:TRM4(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 2(gene name synonym)|uniprotkb:tRNA methyltransferase 4 homolog(gene name synonym)|uniprotkb:Substrate of AIM1/Aurora kinase B(gene name synonym)|uniprotkb:Myc-induced SUN domain-containing protein(gene name synonym)|uniprotkb:"mRNA cytosine C(5)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA cytosine C(5)-methyltransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001180384.1|refseq:NP_060225.4|dip:DIP-52456N|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006400"(tRNA modification)|go:"GO:0007286"(spermatid development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016428"("tRNA (cytosine-5-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0033313"(meiotic cell cycle checkpoint signaling)|go:"GO:0033391"(chromatoid body)|go:"GO:0036416"(tRNA stabilization)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051301"(cell division)|go:"GO:0062152"("mRNA (cytidine-5-)-methyltransferase activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR023270|interpro:IPR029063|mint:Q08J23|reactome:R-HSA-6782315|ensembl:ENSG00000037474(gene)|ensembl:ENST00000264670(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001510"(RNA methylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:k3hK/9cjuy5c4PyDGgCt0LsVtdo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P18621 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-726937|uniprotkb:Q6NZ54|uniprotkb:Q7M4M5|uniprotkb:Q3KQW2|uniprotkb:B2R4H3|uniprotkb:B4E3C2|uniprotkb:B5ME31|uniprotkb:J3QL51|ensembl:ENSP00000462023|ensembl:ENSP00000462385|ensembl:ENSP00000463842|ensembl:ENSP00000480555|ensembl:ENSP00000482577 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl17_human(display_long)|uniprotkb:60S ribosomal protein L23(gene name synonym)|uniprotkb:PD-1(gene name synonym)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short)|uniprotkb:Large ribosomal subunit protein uL22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000976.1|refseq:NP_001030178.1|refseq:NP_001186269.1|refseq:NP_001186270.1|refseq:NP_001186271.1|refseq:NP_001186272.1|refseq:NP_001186273.1|refseq:NP_001186274.1|ensembl:ENSG00000265681(gene)|ensembl:ENST00000579248(transcript)|ensembl:ENST00000579408(transcript)|ensembl:ENST00000580261(transcript)|ensembl:ENST00000618613(transcript)|ensembl:ENST00000618619(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394|mint:P18621|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:/i0W3WoeFakz+8R/YMYf2JQZytI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y3T9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q5BKZ1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2560158|uniprotkb:Q6NSA2|uniprotkb:B4DLN0|uniprotkb:Q7Z638|uniprotkb:Q7Z6C2|uniprotkb:Q5VW97|uniprotkb:Q5VW96|uniprotkb:Q5VW94|uniprotkb:Q5VW93|ensembl:ENSP00000340796|uniprotkb:A8MYX1|uniprotkb:B4E179 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:zn326_human(display_long)|uniprotkb:ZNF326(gene name)|psi-mi:ZNF326(display_short)|uniprotkb:ZIRD(gene name synonym)|uniprotkb:Zinc finger protein 326(gene name synonym)|uniprotkb:Zinc finger protein interacting with mRNPs and DBC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_892020.1|refseq:NP_892021.1|refseq:XP_011539592.1|ensembl:ENSG00000162664(gene)|ensembl:ENST00000340281(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044609"(DBIRD complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q5BKZ1|refseq:XP_005270836.1|refseq:NP_001307114.1|refseq:NP_861446.2 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:y4ZeI0cWMpNA2nQN/hDk6Zn7XRA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9C0A0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-311406|ensembl:ENSP00000479811|uniprotkb:E9PFZ6|uniprotkb:Q86YZ7 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cntp4_human(display_long)|uniprotkb:CNTNAP4(gene name)|psi-mi:CNTNAP4(display_short)|uniprotkb:CASPR4(gene name synonym)|uniprotkb:KIAA1763(gene name synonym)|uniprotkb:Cell recognition molecule Caspr4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_207837.2|ensembl:ENSG00000152910(gene)|ensembl:ENST00000611870(transcript)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR028875|interpro:IPR036056|mint:Q9C0A0|rcsb pdb:4NXQ|refseq:NP_620481.2|dip:DIP-31652N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:P1oT4UCmiYpfcKPyTC4p4Ao9gbQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NXF1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2371062|uniprotkb:Q5T722|uniprotkb:Q5T723|uniprotkb:Q8NCN8|uniprotkb:Q8TDY0|uniprotkb:B4DYV2|ensembl:ENSP00000364037 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tex10_human(display_long)|uniprotkb:TEX10(gene name)|psi-mi:TEX10(display_short)|uniprotkb:L18(orf name)|uniprotkb:Nbla10363(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060216.2|refseq:NP_001155056.1|ensembl:ENSG00000136891(gene)|ensembl:ENST00000374902(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0071339"(MLL1 complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024679|interpro:IPR037947|mint:Q9NXF1|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:cQcRo1eExRkr/an7wvBN8Ttyatc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62910 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-438408|ensembl:ENSP00000380156|ensembl:ENSP00000380158|ensembl:ENSP00000388674|ensembl:ENSP00000416429|uniprotkb:P02433|uniprotkb:B2R4Q3 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl32_human(display_long)|uniprotkb:RPL32(gene name)|psi-mi:RPL32(display_short)|uniprotkb:Large ribosomal subunit protein eL32(gene name synonym)|uniprotkb:PP9932(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000144713(gene)|ensembl:ENST00000396953(transcript)|ensembl:ENST00000396957(transcript)|ensembl:ENST00000429711(transcript)|ensembl:ENST00000435983(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR001515(Ribosomal protein L32e)|interpro:IPR018263|interpro:IPR036351|mint:P62910|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000985.1|refseq:NP_001007074.1|refseq:NP_001007075.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:8Yhph2ETzWYd07yJcq1cVqsSRjo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62829 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O95478 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2852366|ensembl:ENSP00000483484 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nsa2_human(display_long)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:TINP1(gene name synonym)|uniprotkb:Hairy cell leukemia protein 1(gene name synonym)|uniprotkb:TGF-beta-inducible nuclear protein 1(gene name synonym)|uniprotkb:HUSSY-29(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055701.1|refseq:NP_001258594.1|ensembl:ENSG00000164346(gene)|ensembl:ENST00000610426(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR022309|interpro:IPR039411|mint:O95478 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:UHmCVn1q0LfipKMzSFQUzmVULD49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8N9T8 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-724923|uniprotkb:Q2M1R5|uniprotkb:Q2M1R7|uniprotkb:Q7L5J7|uniprotkb:Q96G92|uniprotkb:Q9BU50|uniprotkb:Q9H6I1|uniprotkb:Q9H978|ensembl:ENSP00000320917 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:kri1_human(display_long)|uniprotkb:KRI1(gene name)|psi-mi:KRI1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_075384.3|ensembl:ENSG00000129347(gene)|ensembl:ENST00000312962(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|interpro:IPR018034|interpro:IPR024626|mint:Q8N9T8 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:sIRmrP/c3tSmEAj1usRGN3R3Bh09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P52701 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96T88 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8TEQ6 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-443630|ensembl:ENSP00000285873|uniprotkb:Q14CV0|uniprotkb:Q8WWV4|uniprotkb:Q969W4|uniprotkb:Q9H9K3|uniprotkb:Q9UFI5 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:gemi5_human(display_long)|uniprotkb:GEMIN5(gene name)|psi-mi:GEMIN5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000082516(gene)|ensembl:ENST00000285873(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0032797"(SMN complex)|go:"GO:0034718"(SMN-Gemin2 complex)|interpro:IPR036322|mint:Q8TEQ6|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5GXH|rcsb pdb:5GXI|rcsb pdb:5H1J|rcsb pdb:5H1K|go:"GO:0043022"(ribosome binding)|rcsb pdb:5H1L|rcsb pdb:5H1M|rcsb pdb:5H3S|rcsb pdb:5H3T|rcsb pdb:5H3U|rcsb pdb:5TEE|rcsb pdb:5TEF|rcsb pdb:5THA|rcsb pdb:6RNQ|rcsb pdb:6RNS|reactome:R-HSA-191859|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|refseq:NP_056280.2|refseq:NP_001239085.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:9D6k6KGv+klNdYzgQClnthCYJuo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62847 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354515|uniprotkb:P16632|uniprotkb:Q7Z3D1|uniprotkb:Q5T0P7|uniprotkb:Q5T0P8|uniprotkb:E7EPK6|ensembl:ENSP00000478869 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs24_human(display_long)|uniprotkb:RPS24(gene name)|psi-mi:RPS24(display_short)|uniprotkb:Small ribosomal subunit protein eS24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001135757.1|refseq:NP_001017.1|refseq:NP_001135755.1|refseq:NP_148982.1|ensembl:ENSG00000138326(gene)|ensembl:ENST00000613865(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001976(Ribosomal protein S24e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR018098|mint:P62847|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6XA1|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:M/qkRxabHx9PFaOM7EwKDOOwu7Q9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y2P8 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-11026509|uniprotkb:Q9NY00|uniprotkb:Q5VYW9|uniprotkb:Q9P044|uniprotkb:Q9H9D0|uniprotkb:D3DRI2|uniprotkb:Q5VZU1|ensembl:ENSP00000371169 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rcl1_human(display_long)|uniprotkb:RCL1(gene name)|psi-mi:RCL1(display_short)|uniprotkb:RNAC(gene name synonym)|uniprotkb:RPC2(gene name synonym)|uniprotkb:RPCL1(gene name synonym)|uniprotkb:RTC2(gene name synonym)|uniprotkb:HSPC338(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001273628.1|refseq:NP_001273629.1|refseq:NP_001273630.1|refseq:NP_005763.3|refseq:XP_011515975.1|ensembl:ENSG00000120158(gene)|ensembl:ENST00000381750(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|interpro:IPR000228(RNA 3'-terminal phosphate cyclase)|interpro:IPR013791(RNA 3'-terminal phosphate cyclase, subset, insert region)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR016443(RNA 3'-terminal phosphate cyclase-like, eukaryotic)|interpro:IPR020719|interpro:IPR023797|interpro:IPR036553|interpro:IPR037136|mint:Q9Y2P8|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:XP_016869665.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:8WnLDVPrx4t1eD6h+emL5waEyDY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8NEM2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-744700|uniprotkb:Q96N60|uniprotkb:Q9BVS0|uniprotkb:Q9H6P6|ensembl:ENSP00000306473 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:shcbp_human(display_long)|uniprotkb:SHCBP1(gene name)|psi-mi:SHCBP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_079021.3|ensembl:ENSG00000171241(gene)|ensembl:ENST00000303383(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR039448|mint:Q8NEM2 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:VkqhT9kcant5+JwTeubTotVcLfo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BY42 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1045669|uniprotkb:Q9BYL7|uniprotkb:Q9HCV9|uniprotkb:Q9NX29|uniprotkb:Q9NZZ8|uniprotkb:Q9P002|uniprotkb:Q9UHW3|uniprotkb:E1P5Z9|ensembl:ENSP00000349906 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rtf2_human(display_long)|uniprotkb:RTF2(gene name)|psi-mi:RTF2(display_short)|uniprotkb:C20orf43(gene name synonym)|uniprotkb:RTFDC1(gene name synonym)|uniprotkb:Replication termination factor 2 domain-containing protein 1(gene name synonym)|uniprotkb:AD-007(orf name)|uniprotkb:CDA05(orf name)|uniprotkb:HSPC164(orf name)|uniprotkb:HSPC169(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001269964.1|refseq:NP_001269965.1|refseq:NP_001269966.1|refseq:NP_057491.2|ensembl:ENSG00000022277(gene)|go:"GO:0003677"(DNA binding)|ensembl:ENST00000357348(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0071171"(site-specific DNA replication termination at RTS1 barrier)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1902979"(mitotic DNA replication termination)|interpro:IPR006735(Protein of unknown function DUF602)|interpro:IPR027799 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:eh/6sc/MIM9QOLgd0NfZaezJ7ek9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15397 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-725523|uniprotkb:Q547G7|uniprotkb:Q5SZY9|uniprotkb:Q6IB47|uniprotkb:Q96B27|uniprotkb:Q96L78|uniprotkb:Q96L79|uniprotkb:Q96L80|uniprotkb:A8K804|ensembl:ENSP00000380982 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pum3_human(display_long)|uniprotkb:PUM3(gene name)|psi-mi:PUM3(display_short)|uniprotkb:cPERP-C(gene name synonym)|uniprotkb:HBV X-transactivated gene 5 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 5(gene name synonym)|uniprotkb:KIAA0020(gene name synonym)|uniprotkb:Minor histocompatibility antigen HA-8(gene name synonym)|uniprotkb:PUF-A(gene name synonym)|uniprotkb:XTP5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_055693.4|ensembl:ENSG00000080608(gene)|ensembl:ENST00000397885(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006417"(regulation of translation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012959(CPL)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR040059|mint:Q15397|rcsb pdb:4WZR|rcsb pdb:4WZW - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:CjfVWg+3P3ai0EiHgeH8usbvgxg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P55060 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O00567 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q13310 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P56182 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P50454 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y5Q8 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1045409|uniprotkb:Q8N2U7|uniprotkb:Q8N857|uniprotkb:Q96GD9|uniprotkb:Q9H4P2|uniprotkb:A6NI44|uniprotkb:A6NJB9|uniprotkb:Q5T7U2|uniprotkb:Q5T7U3|intact:EBI-2556713|ensembl:ENSP00000361169 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tf3c5_human(display_long)|uniprotkb:Transcription factor IIIC subunit epsilon(gene name synonym)|uniprotkb:TF3C-epsilon(gene name synonym)|uniprotkb:Transcription factor IIIC 63 kDa subunit(gene name synonym)|uniprotkb:GTF3C5(gene name)|psi-mi:GTF3C5(display_short)|uniprotkb:CDABP0017(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001116295.1|refseq:NP_036219.2|ensembl:ENSG00000148308(gene)|ensembl:ENST00000372097(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR019136|interpro:IPR040454|interpro:IPR041499|interpro:IPR042536|mint:Q9Y5Q8|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|refseq:NP_001273638.1|dip:DIP-50823N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Cb1wPs3qn4+Up/g7WgOMDEFtp+M9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96HS1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-713608|uniprotkb:Q96JB0|intact:EBI-2555528|ensembl:ENSP00000438465|uniprotkb:C9IZY7|uniprotkb:A9LN06 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pgam5_human(display_long)|uniprotkb:Bcl-XL-binding protein v68(gene name synonym)|uniprotkb:PGAM5(gene name)|psi-mi:PGAM5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001164014.1|refseq:NP_612642.2|ensembl:ENSG00000247077(gene)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016791"(phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q96HS1|rcsb pdb:3MXO|rcsb pdb:3O0T|rcsb pdb:5MUF|rcsb pdb:6CNI|rcsb pdb:6CNL|reactome:R-HSA-8934903|ensembl:ENST00000498926(transcript)|dip:DIP-50735N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:prE0I+tNIEjN9Y1NBZbh51DY2+Q9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q6RFH5 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-722366|uniprotkb:Q9BRC9|uniprotkb:Q9H6X8|uniprotkb:Q9NVY2|uniprotkb:A8K8G5|ensembl:ENSP00000278856|ensembl:ENSP00000432119|ensembl:ENSP00000435726 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:wdr74_human(display_long)|uniprotkb:NOP seven-associated protein 1(gene name synonym)|uniprotkb:WDR74(gene name)|psi-mi:WDR74(display_short)|uniprotkb:NSA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060563.2|refseq:XP_005274112.1|refseq:NP_001294906.1|ensembl:ENSG00000133316(gene)|ensembl:ENST00000278856(transcript)|ensembl:ENST00000525239(transcript)|ensembl:ENST00000529106(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037379|mint:Q6RFH5 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:KGh4kcZ85zi1yj6Ow10pW3h7ECM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y4W2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1051591|uniprotkb:Q5JXQ0|uniprotkb:Q8TEN5|uniprotkb:Q9H9V5|uniprotkb:A9X410|ensembl:ENSP00000363944 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:las1l_human(display_long)|uniprotkb:LAS1L(gene name)|psi-mi:LAS1L(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)|uniprotkb:MSTP060(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001164120.1|refseq:NP_001164121.1|refseq:NP_112483.1|ensembl:ENSG00000001497(gene)|ensembl:ENST00000374811(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:Q9Y4W2|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:1TTE2TCMIwczNaT2SSMLioLkALA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P61513 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356793|uniprotkb:P12751|intact:EBI-1051378|uniprotkb:Q6FGF5|ensembl:ENSP00000418082 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl37a_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:Large ribosomal subunit protein eL43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000989.1|ensembl:ENSG00000197756(gene)|ensembl:ENST00000491306(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P61513|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:0kwO2cVd99FGF2+5FyWo94C83049606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q5C9Z4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2685618|uniprotkb:Q96I08|ensembl:ENSP00000275820 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nom1_human(display_long)|uniprotkb:C7orf3(gene name synonym)|uniprotkb:SGD1 homolog(gene name synonym)|uniprotkb:NOM1(gene name)|psi-mi:NOM1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_612409.1|ensembl:ENSG00000146909(gene)|ensembl:ENST00000275820(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0048820"(hair follicle maturation)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:Q5C9Z4 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:1LScd95yytIZJ1/UFg9WTUiCmqg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NVX2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-743801|uniprotkb:O60868|uniprotkb:Q9BU54|uniprotkb:Q59GJ8|ensembl:ENSP00000413572 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nle1_human(display_long)|uniprotkb:NLE1(gene name)|psi-mi:NLE1(display_short)|uniprotkb:HUSSY-07(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001014445.1|refseq:NP_060566.2|ensembl:ENSG00000073536(gene)|ensembl:ENST00000442241(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0001756"(somitogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR012972(NLE)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:6WAJ|refseq:XP_016880266.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:PLVqsV9l43DeUpBELxS8+0ks2tM9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BQ39 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-395850|intact:EBI-2826089|uniprotkb:Q8WV76|uniprotkb:Q9BWI8|uniprotkb:Q5VX37|ensembl:ENSP00000362687 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx50_human(display_long)|uniprotkb:DEAD box protein 50(gene name synonym)|uniprotkb:Nucleolar protein Gu2(gene name synonym)|uniprotkb:Gu-beta(gene name synonym)|uniprotkb:DDX50(gene name)|psi-mi:DDX50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_076950.1|ensembl:ENSG00000107625(gene)|ensembl:ENST00000373585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9BQ39|rcsb pdb:2E29|refseq:XP_016872115.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:a8/VHQw5HVQh6L/rbsKonz0R34c9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y2X3 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-395469|uniprotkb:Q53SA4|uniprotkb:Q6PK08|uniprotkb:Q9P036|uniprotkb:Q9UFN3|ensembl:ENSP00000264279 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nop58_human(display_long)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOL5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP5(gene name synonym)|uniprotkb:HSPC120(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_057018.1|ensembl:ENSG00000055044(gene)|ensembl:ENST00000264279(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|go:"GO:0016020"(membrane)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q9Y2X3|reactome:R-HSA-4570464|reactome:R-HSA-6790901|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|reactome:R-HSA-6791226|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|dip:DIP-32926N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:L7mE30ZNpQbKsQElFrrDMBQwG+w9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q92522 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P46783 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354442|uniprotkb:Q5TZC0|uniprotkb:B2R4E3|ensembl:ENSP00000481646|ensembl:ENSP00000494190|ensembl:ENSP00000494440|ensembl:ENSP00000497917 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs10_human(display_long)|uniprotkb:RPS10(gene name)|psi-mi:RPS10(display_short)|uniprotkb:Small ribosomal subunit protein eS10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001005.1|refseq:NP_001190174.1|refseq:NP_001191020.1|ensembl:ENSG00000124614(gene)|ensembl:ENST00000464218(transcript)|ensembl:ENST00000467531(transcript)|ensembl:ENST00000621356(transcript)|ensembl:ENST00000648437(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR005326(Plectin/S10, N-terminal)|rcsb pdb:6G51|interpro:IPR036388|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|interpro:IPR037447|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|mint:P46783|rcsb pdb:4UG0|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:4V6X|rcsb pdb:6ZUO|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|rcsb pdb:5T2C|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:GWUAJh7s0w/ar/SOpx0hiIJOr2c9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BVP2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-641642|uniprotkb:Q96SV6|uniprotkb:Q96SV7|uniprotkb:Q9UJY0|intact:EBI-2559594|intact:EBI-718302|uniprotkb:B2RDC1|uniprotkb:Q5PU80|intact:EBI-28973725|ensembl:ENSP00000395772 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:gnl3_human(display_long)|uniprotkb:Nucleolar GTP-binding protein 3(gene name synonym)|uniprotkb:Nucleostemin(gene name synonym)|uniprotkb:E2-induced gene 3 protein(gene name synonym)|uniprotkb:Novel nucleolar protein 47(gene name synonym)|uniprotkb:GNL3(gene name)|psi-mi:GNL3(display_short)|uniprotkb:E2IG3(gene name synonym)|uniprotkb:NS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENST00000394799|ensembl:ENSP00000378278|ensembl:ENSP00000395772|refseq:NP_055181.3|refseq:NP_996561.1|refseq:NP_996562.1|ensembl:ENSG00000163938(gene)|ensembl:ENST00000418458(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030496"(midbody)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|interpro:IPR006073(GTP1/OBG)|interpro:IPR014813(GNL3L/Grn1 putative GTPase)|interpro:IPR027417|interpro:IPR030378|mint:Q9BVP2|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:c1DgvQoZ51edxvnCa6GFhfNRR7M9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62241 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-351811|uniprotkb:Q6IRL7|uniprotkb:P09058|ensembl:ENSP00000379888 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rs8_human(display_long)|uniprotkb:RPS8(gene name)|psi-mi:RPS8(display_short)|uniprotkb:Small ribosomal subunit protein eS8(gene name synonym)|uniprotkb:OK/SW-cl.83(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001003.1|ensembl:ENSG00000142937(gene)|ensembl:ENST00000396651(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR018283|interpro:IPR022309|interpro:IPR042563|mint:P62241|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:6G5H|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975957|reactome:R-HSA-975956 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:3rpCBdQyRWR+TCKnupbnCp30jKE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q07021 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14444 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1047080|uniprotkb:Q15074|intact:EBI-1171814|uniprotkb:Q6IMN4|uniprotkb:A6NMY7|uniprotkb:Q6IMN7|uniprotkb:Q9BV09|intact:EBI-2562858|intact:EBI-3449178|uniprotkb:D3DR06|ensembl:ENSP00000340329|ensembl:ENSP00000434150 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:capr1_human(display_long)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNG105(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005889.3|refseq:NP_976240.1|ensembl:ENSG00000135387(gene)|ensembl:ENST00000341394(transcript)|ensembl:ENST00000532820(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0045202"(synapse)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|interpro:IPR022070|interpro:IPR028816|interpro:IPR041637|mint:Q14444|rcsb pdb:4WBE|rcsb pdb:4WBP|rcsb pdb:6TA7|refseq:XP_016873238.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:3c6ZdBClP/D6jIi8NfzBkMc61pI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P27635 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O43809 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BYG3 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2561019|ensembl:ENSP00000285814|uniprotkb:Q8TB66|uniprotkb:A8K788|uniprotkb:Q96ED4 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mk67i_human(display_long)|uniprotkb:NIFK(gene name)|psi-mi:NIFK(display_short)|uniprotkb:MKI67IP(gene name synonym)|uniprotkb:NOPP34(gene name synonym)|uniprotkb:Nucleolar phosphoprotein Nopp34(gene name synonym)|uniprotkb:Nucleolar protein interacting with the FHA domain of pKI-67(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021043|interpro:IPR035979|mint:Q9BYG3|rcsb pdb:2AFF|ensembl:ENSG00000155438(gene)|ensembl:ENST00000285814(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_115766.3|dip:DIP-28134N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:DUc8AnzFxJjbK+cTW5H83GQcf6o9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q86U42 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1226435|uniprotkb:O43484|uniprotkb:D3DS49|ensembl:ENSP00000216727 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pabp2_human(display_long)|uniprotkb:PABPN1(gene name)|psi-mi:PABPN1(display_short)|uniprotkb:PAB2(gene name synonym)|uniprotkb:PABP2(gene name synonym)|uniprotkb:"Poly(A)-binding protein II"(gene name synonym)|uniprotkb:Polyadenylate-binding nuclear protein 1(gene name synonym)|uniprotkb:"Nuclear poly(A)-binding protein 1"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004634.1|dip:DIP-37968N|go:"GO:0000165"(MAPK cascade)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|ensembl:ENSG00000100836(gene)|ensembl:ENST00000216727(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1904247"(positive regulation of polynucleotide adenylyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034911|interpro:IPR035979|mint:Q86U42|rcsb pdb:3B4D|rcsb pdb:3B4M|rcsb pdb:3UCG|reactome:R-HSA-168315|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0070063"(RNA polymerase binding) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:NxWuFTvVqshfu+ZIsZMIZEdSk2k9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P19525 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-640775|uniprotkb:D6W584|uniprotkb:Q52M43|uniprotkb:Q9UIR4|uniprotkb:A8K3P0|ensembl:ENSP00000233057|ensembl:ENSP00000378559|ensembl:ENSP00000497534|ensembl:ENSP00000505138|ensembl:ENSP00000505772|ensembl:ENSP00000506024|uniprotkb:E9PC80|uniprotkb:Q7Z6F6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:e2ak2_human(display_long)|uniprotkb:Interferon-inducible RNA-dependent protein kinase(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2-alpha kinase 2(gene name synonym)|uniprotkb:Protein kinase RNA-activated(gene name synonym)|uniprotkb:p68 kinase(gene name synonym)|uniprotkb:P1/eIF-2A protein kinase(gene name synonym)|uniprotkb:EIF2AK2(gene name)|psi-mi:EIF2AK2(display_short)|uniprotkb:PKR(gene name synonym)|uniprotkb:PRKR(gene name synonym)|uniprotkb:Tyrosine-protein kinase EIF2AK2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001129124.1|refseq:NP_001129123.1|refseq:NP_002750.1|ensembl:ENSG00000055332(gene)|ensembl:ENST00000233057(transcript)|ensembl:ENST00000395127(transcript)|ensembl:ENST00000647926(transcript)|ensembl:ENST00000679507(transcript)|ensembl:ENST00000681463(transcript)|ensembl:ENST00000681507(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044452|interpro:IPR044453|mint:P19525|rcsb pdb:1QU6|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3UIU|rcsb pdb:6D3K|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|rcsb pdb:6D3L|reactome:R-HSA-1169408|go:"GO:0051607"(defense response to virus)|reactome:R-HSA-169131|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900225"(regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901532"(regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902033"(regulation of hematopoietic stem cell proliferation)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-2657N|refseq:XP_011531289.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:2Pc405Bc/xKDHC1O24GhGC5JJzU9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O76094 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1058850|ensembl:ENSP00000495128|intact:EBI-2654733|uniprotkb:G5E9Z8|uniprotkb:Q7Z3C0 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:srp72_human(display_long)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_008878.3|refseq:NP_001254651.1|ensembl:ENSG00000174780(gene)|ensembl:ENST00000642900(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030911"(TPR domain binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR019734|interpro:IPR026270|interpro:IPR031545|mint:O76094|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:5WRW|rcsb pdb:7NFX|reactome:R-HSA-1799339 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:NJfyOcmKiBWszQsH0EQotsdwhU09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P61353 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q07666 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1364|uniprotkb:Q6PJX7|uniprotkb:Q8NB97|uniprotkb:Q99760|uniprotkb:D3DPP3|ensembl:ENSP00000313829 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:khdr1_human(display_long)|uniprotkb:SAM68(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:KHDRBS1(gene name)|psi-mi:KHDRBS1(display_short)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:p68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006550.1|refseq:NP_001258807.1|dip:DIP-29007N|ensembl:ENSG00000121774(gene)|ensembl:ENST00000327300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q07666|rcsb pdb:2XA6|rcsb pdb:3QHE|reactome:R-HSA-8849468 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:po7jC4Nxu+Aoz6T8K6VRWHp6MKQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P42696 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2954772|ensembl:ENSP00000386226|uniprotkb:Q8N2Z8|uniprotkb:Q9H5A1|uniprotkb:A8K8J7 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rbm34_human(display_long)|uniprotkb:RBM34(gene name)|psi-mi:RBM34(display_short)|uniprotkb:KIAA0117(gene name synonym)|uniprotkb:RNA-binding motif protein 34(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000188739(gene)|ensembl:ENST00000408888(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR034220|interpro:IPR034221|interpro:IPR035979|mint:P42696|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:NP_055829.2|refseq:NP_001333667.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:YrlnOTpyzg9F+4ZaZpLMfq4T4ts9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NVP1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-724378|ensembl:ENSP00000263239|uniprotkb:Q6GTZ9|uniprotkb:Q6IAU4|uniprotkb:Q92732|uniprotkb:Q9BQB7 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx18_human(display_long)|uniprotkb:DEAD box protein 18(gene name synonym)|uniprotkb:Myc-regulated DEAD box protein(gene name synonym)|uniprotkb:DDX18(gene name)|psi-mi:DDX18(display_short)|uniprotkb:cPERP-D(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_006764.3|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR025313|interpro:IPR027417|interpro:IPR044773|mint:Q9NVP1|rcsb pdb:3LY5|ensembl:ENSG00000088205(gene)|ensembl:ENST00000263239(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0071392"(cellular response to estradiol stimulus) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:RmupZbt33/w1V7Uq5vnRO36j2Tc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y678 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_057212.1|ensembl:ENSG00000181789(gene)|ensembl:ENST00000314797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q16181 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8N684 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-746909|uniprotkb:C9K0Q4|uniprotkb:Q7Z3H9|uniprotkb:Q9H025|uniprotkb:Q9H9V1|uniprotkb:B3KU04|ensembl:ENSP00000378352 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:cpsf7_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001129512.1|refseq:NP_001136037.1|refseq:NP_079087.3|refseq:XP_011543560.1|refseq:XP_011543561.1|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0016020"(membrane)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034770|interpro:IPR034772|interpro:IPR034773|interpro:IPR035979|mint:Q8N684|rcsb pdb:3N9U|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|ensembl:ENSG00000149532(gene)|ensembl:ENST00000394888(transcript)|refseq:XP_005274356.1|reactome:R-HSA-9013422 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:bfliZhw27GRZMSQpYRZ/x/tWGh49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UBM7 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1054468|uniprotkb:O60492|uniprotkb:O60717|uniprotkb:B2R6Z2|ensembl:ENSP00000347717|ensembl:ENSP00000384739 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:dhcr7_human(display_long)|uniprotkb:"Sterol Delta(7)-reductase"(gene name synonym)|uniprotkb:DHCR7(gene name)|psi-mi:DHCR7(display_short)|uniprotkb:D7SR(gene name synonym)|uniprotkb:Delta7-sterol reductase(gene name synonym)|uniprotkb:Sterol reductase SR-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001157289.1|refseq:NP_001351.2|mint:Q9UBM7|reactome:R-HSA-2426168|reactome:R-HSA-6807047|reactome:R-HSA-6807062|interpro:IPR018083|ensembl:ENSG00000172893(gene)|ensembl:ENST00000355527(transcript)|ensembl:ENST00000407721(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0009918"(sterol delta7 reductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016132"(brassinosteroid biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0047598"(7-dehydrocholesterol reductase activity)|go:"GO:0050661"(NADP binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:op53bBpGaOM0Ysy4Bn5q6qXcKgI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14137 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1050828|uniprotkb:Q969Z6|uniprotkb:Q96IS8|uniprotkb:Q9BSA7|uniprotkb:Q9BVM0|ensembl:ENSP00000455106|ensembl:ENSP00000495401|uniprotkb:Q96Q25 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:bop1_human(display_long)|uniprotkb:Block of proliferation 1 protein(gene name synonym)|uniprotkb:BOP1(gene name)|psi-mi:BOP1(display_short)|uniprotkb:KIAA0124(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_056016.1|ensembl:ENSG00000261236(gene)|ensembl:ENSG00000285301(gene)|ensembl:ENST00000569669(transcript)|ensembl:ENST00000642409(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR012953(BOP1, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028598|interpro:IPR036322|mint:Q14137|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:g2CwsRotXBvjvr+rSZSA0mKrVCY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P23246 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y3C1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P19338 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q00325 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 - - crc64:78714C85931B22D5 figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P30536 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-6623146|ensembl:ENSP00000328973|ensembl:ENSP00000338004|ensembl:ENSP00000379563|uniprotkb:Q53Y59|uniprotkb:Q6ICF9|uniprotkb:Q96TF6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tspo_human(display_long)|uniprotkb:TSPO(gene name)|psi-mi:TSPO(display_short)|uniprotkb:BZRP(gene name synonym)|uniprotkb:MBR(gene name synonym)|uniprotkb:Mitochondrial benzodiazepine receptor(gene name synonym)|uniprotkb:PKBS(gene name synonym)|uniprotkb:Peripheral-type benzodiazepine receptor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000100300(gene)|ensembl:ENST00000329563(transcript)|ensembl:ENST00000337554(transcript)|ensembl:ENST00000396265(transcript)|go:"GO:0005497"(androgen binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006700"(C21-steroid hormone biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006820"(anion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0007568"(aging)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008347"(glial cell migration)|go:"GO:0008503"(benzodiazepine receptor activity)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010266"(response to vitamin B1)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030325"(adrenal gland development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060242"(contact inhibition)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0032570"(response to progesterone)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1903147"(negative regulation of autophagy of mitochondrion)|go:"GO:1903579"(negative regulation of ATP metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004307(TspO/MBR-related protein)|interpro:IPR030164|interpro:IPR038330|reactome:R-HSA-196108|go:"GO:0033574"(response to testosterone)|refseq:NP_000705.2|refseq:NP_001243459.1|refseq:NP_001243460.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:A8KFWbHly01w8pFFNMygS76hCdI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O76021 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-358028|uniprotkb:Q2M1T7|uniprotkb:Q6PL22|uniprotkb:Q8IWS7|uniprotkb:Q8WUZ1|uniprotkb:Q9HDA9|uniprotkb:Q9Y3Z9|uniprotkb:B4DJ58|uniprotkb:D3DUG7|ensembl:ENSP00000460871 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl1d1_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short)|uniprotkb:CSIG(gene name synonym)|uniprotkb:PBK1(gene name synonym)|uniprotkb:CATX11(gene name synonym)|uniprotkb:L12(orf name)|uniprotkb:Cellular senescence-inhibited gene protein(gene name synonym)|uniprotkb:Protein PBK1(gene name synonym)|uniprotkb:CATX-11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_056474.2|ensembl:ENSG00000171490(gene)|ensembl:ENST00000571133(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:O76021 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:/mAkpodrvvZA6mz3M8VwHDEJzKo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8WTT2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2512539|ensembl:ENSP00000360412|uniprotkb:Q9H9D8|uniprotkb:Q9H5M6 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:noc3l_human(display_long)|uniprotkb:NOC3L(gene name)|psi-mi:NOC3L(display_short)|uniprotkb:AD24(gene name synonym)|uniprotkb:C10orf117(gene name synonym)|uniprotkb:FAD24(gene name synonym)|uniprotkb:NOC3-like protein(gene name synonym)|uniprotkb:Nucleolar complex-associated protein 3-like protein(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045444"(fat cell differentiation)|interpro:IPR005612(CBF)|interpro:IPR011501(Nucleolar complex-associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016903(Nucleolar complex-associated protein 3)|mint:Q8WTT2|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000173145(gene)|ensembl:ENST00000371361(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|refseq:NP_071896.8 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:s78IiBuQQjc0emiM/UkEMhzThVc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P46777 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-358018|ensembl:ENSP00000359345|uniprotkb:Q53HH6|uniprotkb:Q9H3F4|uniprotkb:Q32LZ3 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl5_human(display_long)|uniprotkb:RPL5(gene name)|psi-mi:RPL5(display_short)|uniprotkb:Large ribosomal subunit protein uL18(gene name synonym)|uniprotkb:MSTP030(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|ensembl:ENSG00000122406(gene)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENST00000370321(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|refseq:NP_000960.2|dip:DIP-31152N|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P46777|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:rs+zAc+IPrEqv7DHNcy2GIkQkfY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BXY0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-5280229|uniprotkb:B2RB44|uniprotkb:Q5U5T1|uniprotkb:Q86UC4|uniprotkb:Q96SY6|ensembl:ENSP00000353246 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mak16_human(display_long)|uniprotkb:MAK16(gene name)|psi-mi:MAK16(display_short)|uniprotkb:RBM13(gene name synonym)|uniprotkb:NNP78(gene name synonym)|uniprotkb:Protein RBM13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_115898.2|ensembl:ENSG00000198042(gene)|ensembl:ENST00000360128(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR006958(Mak16 protein)|interpro:IPR029004|mint:Q9BXY0 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Zedk3AV8WcIUeBxPWbFlL6HztIA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q96QC0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694|ensembl:ENSP00000373080|ensembl:ENSP00000389299|ensembl:ENSP00000407181|ensembl:ENSP00000407310|ensembl:ENSP00000413554|ensembl:ENSP00000416060 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|dip:DIP-39343N|ensembl:ENSG00000204569(gene)|ensembl:ENSG00000206489(gene)|ensembl:ENSG00000227804(gene)|ensembl:ENSG00000230995(gene)|ensembl:ENSG00000231737(gene)|ensembl:ENSG00000235291(gene)|ensembl:ENSG00000238104(gene)|ensembl:ENST00000376511(transcript)|ensembl:ENST00000383586(transcript)|ensembl:ENST00000420949(transcript)|ensembl:ENST00000424446(transcript)|ensembl:ENST00000426299(transcript)|ensembl:ENST00000429597(transcript)|ensembl:ENST00000449113(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:1904290"(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|go:"GO:0000785"(chromatin) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y3U8 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P49585 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2563309|uniprotkb:Q86Y88|uniprotkb:A9LYK9|uniprotkb:D3DXB1|ensembl:ENSP00000292823|ensembl:ENSP00000394617 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pcy1a_human(display_long)|uniprotkb:PCYT1A(gene name)|psi-mi:PCYT1A(display_short)|uniprotkb:CTPCT(gene name synonym)|uniprotkb:PCYT1(gene name synonym)|uniprotkb:Phosphorylcholine transferase A(gene name synonym)|uniprotkb:"CTP:phosphocholine cytidylyltransferase A"(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_005008.2|refseq:NP_001299602.1|ensembl:ENSG00000161217(gene)|ensembl:ENST00000292823(transcript)|ensembl:ENST00000431016(transcript)|go:"GO:0004105"(choline-phosphate cytidylyltransferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR041723|mint:P49585|reactome:R-HSA-1483191 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:64kROfRkpFhQ9iL46Q8WetwqBFg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q5JVF3 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1051701|uniprotkb:A6NK09|uniprotkb:Q3ZCX1|uniprotkb:Q5TC57|uniprotkb:Q5TC58|uniprotkb:Q9H7K1|uniprotkb:Q9HBZ7|uniprotkb:Q9NUK6|uniprotkb:Q9NVY1|uniprotkb:Q9NW44|uniprotkb:Q9NWH3|ensembl:ENSP00000337405|ensembl:ENSP00000364626|ensembl:ENSP00000364628 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pcid2_human(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short)|uniprotkb:HT004(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001120674.1|refseq:NP_001120675.1|refseq:NP_060856.2|refseq:NP_001245142.1|refseq:NP_001307584.1|refseq:NP_001307585.1|refseq:NP_001307586.1|refseq:NP_001307589.1|ensembl:ENSG00000126226(gene)|ensembl:ENST00000337344(transcript)|ensembl:ENST00000375477(transcript)|ensembl:ENST00000375479(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|rcsb pdb:3T5X|refseq:XP_016876153.1|dip:DIP-50497N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BZE4 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1056249|uniprotkb:O95446|uniprotkb:Q9NVJ8|uniprotkb:B3KMC5|uniprotkb:B4DY13|uniprotkb:B7Z7A3|uniprotkb:Q5T3R8|ensembl:ENSP00000354040 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:gtpb4_human(display_long)|uniprotkb:GTPBP4(gene name)|psi-mi:GTPBP4(display_short)|uniprotkb:CRFG(gene name synonym)|uniprotkb:NOG1(gene name synonym)|uniprotkb:Chronic renal failure gene protein(gene name synonym)|uniprotkb:GTP-binding protein NGB(gene name synonym)|uniprotkb:Nucleolar GTP-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_036473.2|ensembl:ENSG00000107937(gene)|ensembl:ENST00000360803(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033342"(negative regulation of collagen binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|mint:Q9BZE4|rcsb pdb:6LSS|rcsb pdb:6LU8 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:wTcBrIj6c27um4RnJH81grRgutc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BQ67 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-351000|uniprotkb:Q8TF59|ensembl:ENSP00000253237|intact:EBI-9512815|uniprotkb:A0MNN5 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:grwd1_human(display_long)|uniprotkb:GRWD1(gene name)|psi-mi:GRWD1(display_short)|uniprotkb:GRWD(gene name synonym)|uniprotkb:WDR28(gene name synonym)|uniprotkb:KIAA1942(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 interpro:IPR022052|refseq:NP_113673.3|ensembl:ENSG00000105447(gene)|ensembl:ENST00000253237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|mint:Q9BQ67|interpro:IPR036322 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:rbkcKHsv+l3kFqh4SElBDft0b+A9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:O00541 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1053271|uniprotkb:Q6IC29|ensembl:ENSP00000346725 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pesc_human(display_long)|uniprotkb:PES1(gene name)|psi-mi:PES1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001230154.1|refseq:NP_055118.1|ensembl:ENSG00000100029(gene)|ensembl:ENST00000354694(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001357(BRCT)|interpro:IPR010613(Pescadillo, N-terminal)|interpro:IPR036420|rcsb pdb:2EP8|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Nq1SJ37kJfe+vF9zmNASz1gnbfY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q13823 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1043365|uniprotkb:Q9BWN7|ensembl:ENSP00000362153 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nog2_human(display_long)|uniprotkb:Autoantigen NGP-1(gene name synonym)|uniprotkb:GNL2(gene name)|psi-mi:GNL2(display_short)|uniprotkb:NGP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000134697(gene)|ensembl:ENST00000373062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012971(NGP1, N-terminal)|interpro:IPR023179|interpro:IPR024929|interpro:IPR027417|interpro:IPR030378|mint:Q13823|rcsb pdb:6LSS|rcsb pdb:6LU8|refseq:NP_037417.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:CgIg/QNhk71SHIhV4iLvIuC/HUo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NW13 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-2878099|ensembl:ENSP00000223073|uniprotkb:Q96CV3|uniprotkb:A4D100|uniprotkb:Q53H65|uniprotkb:B4DU52|uniprotkb:E9PDD9 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rbm28_human(display_long)|uniprotkb:RBM28(gene name)|psi-mi:RBM28(display_short)|uniprotkb:RNA-binding motif protein 28(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9NW13|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000106344(gene)|ensembl:ENST00000223073(transcript)|refseq:NP_001159607.1|refseq:NP_060547.2 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:yIPQX+d5YQpq3gpdtBilOXJcUsg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9Y6M1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1024419|intact:EBI-1059063|intact:EBI-1237206|uniprotkb:A0A4Z0|uniprotkb:B3FTN2|uniprotkb:B3FTN3|uniprotkb:B3FTN4|ensembl:ENSP00000371634 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:if2b2_human(display_long)|uniprotkb:IGF-II mRNA-binding protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma autoantigen p62(gene name synonym)|uniprotkb:VICKZ family member 2(gene name synonym)|uniprotkb:IGF2BP2(gene name)|psi-mi:IGF2BP2(display_short)|uniprotkb:IMP2(gene name synonym)|uniprotkb:VICKZ2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001278801.1|refseq:NP_001278802.1|refseq:NP_001278803.1|refseq:NP_001278804.1|refseq:NP_001007226.1|refseq:NP_006539.3|ensembl:ENSG00000073792(gene)|ensembl:ENST00000382199(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR028743|interpro:IPR034843|interpro:IPR035979|interpro:IPR036612|mint:Q9Y6M1|rcsb pdb:2CQH|rcsb pdb:6ROL|reactome:R-HSA-428359|dip:DIP-35539N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:k45UViReMAxCv2cu7+tx+auevQc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P05388 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P57088 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1048629|uniprotkb:Q9H953|uniprotkb:B3KSS8|ensembl:ENSP00000422473|ensembl:ENSP00000427006|ensembl:ENSP00000441455 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:tmm33_human(display_long)|uniprotkb:Protein DB83(gene name synonym)|uniprotkb:TMEM33(gene name)|psi-mi:TMEM33(display_short)|uniprotkb:DB83(gene name synonym)|uniprotkb:SHINC-3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060596.2|refseq:XP_005248173.1|refseq:XP_005248174.1|ensembl:ENSG00000109133(gene)|ensembl:ENST00000325094(transcript)|ensembl:ENST00000504986(transcript)|ensembl:ENST00000513702(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061024"(membrane organization)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR005344(Protein of unknown function UPF0121)|mint:P57088 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:FGc4/gpnYoRtlDJMxQWh5hXe5Ko9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P12236 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9UKD2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1046493|ensembl:ENSP00000364320|uniprotkb:Q9BPV9|uniprotkb:Q5TG55|uniprotkb:Q96SS6|uniprotkb:B3KNB3 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mrt4_human(display_long)|uniprotkb:MRTO4(gene name)|psi-mi:MRTO4(display_short)|uniprotkb:C1orf33(gene name synonym)|uniprotkb:MRT4(gene name synonym)|uniprotkb:Ribosome assembly factor MRTO4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000053372(gene)|ensembl:ENST00000330263(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:Q9UKD2|interpro:IPR033867|refseq:NP_057267.2 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:LpvX3By1Cp6MxlAx3d5qoDM3FNY9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P36578 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-348313|ensembl:ENSP00000311430|uniprotkb:P39029|uniprotkb:Q4VBR0|uniprotkb:Q969Z9|uniprotkb:A8K502 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl4_human(display_long)|uniprotkb:RPL4(gene name)|psi-mi:RPL4(display_short)|uniprotkb:RPL1(gene name synonym)|uniprotkb:60S ribosomal protein L1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000174444(gene)|ensembl:ENST00000307961(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR025755|mint:P36578|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|interpro:IPR023574|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OM0|refseq:NP_000959.2|dip:DIP-27559N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:34il/jyrW0Dqj0eA8GBFgUk05XU9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9NR30 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P39023 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15349 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1384149|uniprotkb:Q15419|uniprotkb:Q59GJ3|uniprotkb:Q5TI68|uniprotkb:Q96J38|uniprotkb:Q9UJN5|uniprotkb:B3KTK9|ensembl:ENSP00000265678 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ks6a2_human(display_long)|uniprotkb:RPS6KA2(gene name)|psi-mi:RPS6KA2(display_short)|uniprotkb:RSK3(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 2(gene name synonym)|uniprotkb:MAPKAPK1C(gene name synonym)|uniprotkb:Ribosomal S6 kinase 3(gene name synonym)|uniprotkb:pp90RSK3(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1c(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001006933.2|refseq:NP_001305865.1|refseq:NP_001305866.1|refseq:NP_001305867.1|refseq:NP_066958.2|dip:DIP-295N|ensembl:ENSG00000071242(gene)|ensembl:ENST00000265678(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001556"(oocyte maturation)|go:"GO:0002035"(brain renin-angiotensin system)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0060047"(heart contraction)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0072687"(meiotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041906|interpro:IPR042766|mint:Q15349|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-2559582|reactome:R-HSA-437239|reactome:R-HSA-442742|reactome:R-HSA-444257|reactome:R-HSA-881907 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:990LeSQ83sti7xG5qGEoFLDkubs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P47914 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q15019 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N - - crc64:12CCBBE30806F92F figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P61313 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-443462|ensembl:ENSP00000309334|ensembl:ENSP00000346867|ensembl:ENSP00000388529|ensembl:ENSP00000416692|ensembl:ENSP00000483260|ensembl:ENSP00000493759|uniprotkb:Q642I1|uniprotkb:Q9H2E5|uniprotkb:P39030|uniprotkb:P41051|uniprotkb:Q6IPX6|uniprotkb:Q8WYP2|uniprotkb:Q96C44|uniprotkb:Q5U0C0|intact:EBI-2877712 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl15_human(display_long)|uniprotkb:RPL15(gene name)|psi-mi:RPL15(display_short)|uniprotkb:EC45(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL15(gene name synonym)|uniprotkb:TCBAP0781(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000174748(gene)|ensembl:ENST00000307839(transcript)|ensembl:ENST00000354811(transcript)|ensembl:ENST00000413699(transcript)|ensembl:ENST00000415719(transcript)|ensembl:ENST00000611050(transcript)|ensembl:ENST00000644185(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:P61313|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002939.2|refseq:NP_001240308.1|refseq:NP_001240309.1|refseq:NP_001240311.1|refseq:NP_001240312.1|refseq:NP_001240313.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:wllGpJicgC5uwkZV6e4QRwDcrBo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8IY81 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-744088|uniprotkb:Q8N3A3|uniprotkb:Q8WXX1|uniprotkb:Q9BWM4|uniprotkb:Q9NXT6|uniprotkb:D3DU22|uniprotkb:B2RCA5|ensembl:ENSP00000396673 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:spb1_human(display_long)|uniprotkb:FTSJ3(gene name)|psi-mi:FTSJ3(display_short)|uniprotkb:SB92(orf name)|uniprotkb:Protein ftsJ homolog 3(gene name synonym)|uniprotkb:Putative rRNA methyltransferase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060117.3|interpro:IPR015507(Ribosomal RNA methyltransferase J)|interpro:IPR024576|interpro:IPR028589|interpro:IPR029063|mint:Q8IY81|reactome:R-HSA-6791226|ensembl:ENSG00000108592(gene)|ensembl:ENST00000427159(transcript)|go:"GO:0000453"(enzyme-directed rRNA 2'-O-methylation)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008650"("rRNA (uridine-2'-O-)-methyltransferase activity")|go:"GO:0016435"("rRNA (guanine) methyltransferase activity")|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0031167"(rRNA methylation)|go:"GO:0062105"(RNA 2'-O-methyltransferase activity)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR012920(Spb1, C-terminal) - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:KIeyMWn9Zktm5lV7XI7v2bRA8og9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P18077 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62424 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9BQG0 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q8TDN6 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1052326|uniprotkb:Q3ZTT4|uniprotkb:Q8N453|uniprotkb:Q96DH1|uniprotkb:A8K0P5|ensembl:ENSP00000338862 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:brx1_human(display_long)|uniprotkb:BRIX1(gene name)|psi-mi:BRIX1(display_short)|uniprotkb:BXDC2(gene name synonym)|uniprotkb:BRIX(gene name synonym)|uniprotkb:Brix domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_060791.3|ensembl:ENSG00000113460(gene)|ensembl:ENST00000336767(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|interpro:IPR007109(Brix)|interpro:IPR026532|mint:Q8TDN6 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Xa2UDOXgdmWyJ7qBZsdInDt9Vaw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P56537 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-372243|uniprotkb:Q6IBN8|uniprotkb:Q96TD5|uniprotkb:B7ZBG9|ensembl:ENSP00000363559|ensembl:ENSP00000363574|ensembl:ENSP00000502429 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:if6_human(display_long)|uniprotkb:EIF6(gene name)|psi-mi:EIF6(display_short)|uniprotkb:ITGB4BP(gene name synonym)|uniprotkb:OK/SW-cl.27(orf name)|uniprotkb:B4 integrin interactor(gene name synonym)|uniprotkb:CAB(gene name synonym)|uniprotkb:"p27(BBP)"(gene name synonym)|uniprotkb:"B(2)GCN homolog"(gene name synonym)|uniprotkb:EIF3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_002203.1|refseq:NP_852131.1|refseq:NP_852133.1|refseq:NP_001254739.1|ensembl:ENSG00000242372(gene)|ensembl:ENST00000374436(transcript)|ensembl:ENST00000374450(transcript)|ensembl:ENST00000675032(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0032868"(response to insulin)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042304"(regulation of fatty acid biosynthetic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR002769(Translation initiation factor IF6)|mint:P56537|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:A0pOylQptNBlSiBKiZre7INejF49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62140 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62888 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-353116|uniprotkb:P04645|uniprotkb:Q502Z6|ensembl:ENSP00000287038|ensembl:ENSP00000428085|uniprotkb:B2R591 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl30_human(display_long)|uniprotkb:RPL30(gene name)|psi-mi:RPL30(display_short)|uniprotkb:Large ribosomal subunit protein eL30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSG00000156482(gene)|ensembl:ENST00000287038(transcript)|ensembl:ENST00000521291(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000231(Ribosomal protein L30e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR022991|interpro:IPR029064|interpro:IPR039109|mint:P62888|rcsb pdb:3VI6|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000980.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:xR9LwYg6N7m9njT1pYumOPKZVu49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q99848 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P46087 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356811|uniprotkb:A1A4Z3|uniprotkb:Q0P5S5|uniprotkb:Q58F30|uniprotkb:B3KPD6|uniprotkb:Q05BA7|uniprotkb:Q3KQS4|ensembl:ENSP00000313272|ensembl:ENSP00000444437 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nop2_human(display_long)|uniprotkb:NOP2(gene name)|psi-mi:NOP2(display_short)|uniprotkb:NSUN1(gene name synonym)|uniprotkb:Proliferating-cell nucleolar antigen p120(gene name synonym)|uniprotkb:Proliferation-associated nucleolar protein p120(gene name synonym)|uniprotkb:NOL1(gene name synonym)|uniprotkb:Nucleolar protein 2 homolog(gene name synonym)|uniprotkb:Nucleolar protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001028886.1|refseq:NP_006161.2|refseq:NP_001245237.1|refseq:NP_001245238.1|refseq:NP_001245239.1|refseq:XP_005253748.1|ensembl:ENSG00000111641(gene)|ensembl:ENST00000322166(transcript)|ensembl:ENST00000537442(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009383"("rRNA (cytosine-C5-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR011023(Nop2p)|interpro:IPR012586(P120R)|interpro:IPR018314|interpro:IPR023267|interpro:IPR023273|interpro:IPR029063|interpro:IPR031341|mint:P46087|reactome:R-HSA-6790901|reactome:R-HSA-8869496 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:CvYaCDv8N8OvS0lPFy8jFEFaOTA9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14739 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P26373 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356849|uniprotkb:Q3KQT8|uniprotkb:Q9BPX0|uniprotkb:Q567Q8|uniprotkb:B4DLX3|uniprotkb:F5H1S2|ensembl:ENSP00000307889|ensembl:ENSP00000376811|ensembl:ENSP00000455009 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl13_human(display_long)|uniprotkb:RPL13(gene name)|psi-mi:RPL13(display_short)|uniprotkb:BBC1(gene name synonym)|uniprotkb:Breast basic conserved protein 1(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL13(gene name synonym)|uniprotkb:OK/SW-cl.46(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000968.2|refseq:NP_150254.1|refseq:NP_001230059.1|refseq:NP_001230060.1|ensembl:ENSG00000167526(gene)|ensembl:ENST00000311528(transcript)|ensembl:ENST00000393099(transcript)|ensembl:ENST00000567815(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0060348"(bone development)|interpro:IPR001380(Ribosomal protein L13e)|interpro:IPR018256|mint:P26373|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-192823 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:2SZ+AEe41Ystwj9t9I0Z1cZ5GQ49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62906 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356860|uniprotkb:P52859|uniprotkb:P53025|uniprotkb:Q5TZT6|uniprotkb:Q8J013|uniprotkb:B2R801|ensembl:ENSP00000363018 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl10a_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short)|uniprotkb:NEDD6(gene name synonym)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_009035.3|ensembl:ENSG00000198755(gene)|ensembl:ENST00000322203(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|mint:P62906|rcsb pdb:4UG0|rcsb pdb:4V6X|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|rcsb pdb:6OLG|rcsb pdb:6QZP|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:wrXKX6vzZ3ovXP3yUoL1/r+NGiw9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q14677 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1171113|uniprotkb:Q8NAF1|uniprotkb:Q96E05|uniprotkb:D3DQJ6|uniprotkb:B7Z6F8|intact:EBI-28971708|ensembl:ENSP00000388340 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:epn4_human(display_long)|uniprotkb:CLINT1(gene name)|psi-mi:CLINT1(display_short)|uniprotkb:ENTH(gene name synonym)|uniprotkb:EPN4(gene name synonym)|uniprotkb:EPNR(gene name synonym)|uniprotkb:KIAA0171(gene name synonym)|uniprotkb:Epsin-4(gene name synonym)|uniprotkb:Epsin-related protein(gene name synonym)|uniprotkb:Enthoprotin(gene name synonym)|uniprotkb:Clathrin-interacting protein localized in the trans-Golgi region(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 ensembl:ENSP00000388340|ensembl:ENST00000523094|ensembl:ENSP00000429345|ensembl:ENST00000523908|ensembl:ENSP00000429824|ensembl:ENST00000530742|ensembl:ENSP00000433419|refseq:NP_001182484.1|refseq:NP_001182485.1|refseq:NP_055481.1|ensembl:ENSG00000113282(gene)|ensembl:ENST00000411809(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030544|mint:Q14677|rcsb pdb:1XGW|rcsb pdb:2QY7|rcsb pdb:2V8S|reactome:R-HSA-432722|dip:DIP-45604N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:cflzNAWnEQR6zTr4d+hwfy1doC49606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P49207 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1051893|uniprotkb:Q6FG66|uniprotkb:Q9BUZ2|ensembl:ENSP00000378160|ensembl:ENSP00000378162|ensembl:ENSP00000378163|ensembl:ENSP00000423316|ensembl:ENSP00000423983 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl34_human(display_long)|uniprotkb:RPL34(gene name)|psi-mi:RPL34(display_short)|uniprotkb:Large ribosomal subunit protein eL34(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000986.2|refseq:NP_296374.1|refseq:NP_001306161.1|refseq:NP_001306163.1|refseq:NP_001306164.1|refseq:NP_001306165.1|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:6Y6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR008195(Ribosomal protein L34e)|interpro:IPR018065|mint:P49207|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|ensembl:ENSG00000109475(gene)|ensembl:ENST00000394665(transcript)|ensembl:ENST00000394667(transcript)|ensembl:ENST00000394668(transcript)|ensembl:ENST00000502534(transcript)|ensembl:ENST00000506397(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:NSGnIE6uSimeraPQ7ZZ+xRugABg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9H7B2 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1051960|uniprotkb:Q8N4A1|uniprotkb:Q5VXN1|ensembl:ENSP00000402338 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rpf2_human(display_long)|uniprotkb:RPF2(gene name)|psi-mi:RPF2(display_short)|uniprotkb:BXDC1(gene name synonym)|uniprotkb:Ribosome biogenesis protein RPF2 homolog(gene name synonym)|uniprotkb:Brix domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_115570.1|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007109(Brix)|interpro:IPR039770|mint:Q9H7B2|ensembl:ENSG00000197498(gene)|ensembl:ENST00000441448(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:CXU4CHQmcrISLS8GDIwEMGhiaQI9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P50914 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-356746|uniprotkb:Q45RF0|uniprotkb:Q53G20|uniprotkb:Q8TBD5|uniprotkb:Q8WUT0|uniprotkb:Q92579|uniprotkb:Q96GR0|uniprotkb:Q9BSB8|uniprotkb:Q9BW65|uniprotkb:Q9BYF6|ensembl:ENSP00000345156|ensembl:ENSP00000379506 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl14_human(display_long)|uniprotkb:RPL14(gene name)|psi-mi:RPL14(display_short)|uniprotkb:CAG-ISL 7(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001030168.1|refseq:NP_003964.3|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|ensembl:ENSG00000188846(gene)|ensembl:ENST00000338970(transcript)|ensembl:ENST00000396203(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041985|mint:P50914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|interpro:IPR039660|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y2L - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:AjaguD5hgHtcBbJq5QfuG6XdTcE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62913 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354380|uniprotkb:P25121|uniprotkb:P39026|uniprotkb:Q8TDH2|uniprotkb:Q9Y674|ensembl:ENSP00000496250 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl11_human(display_long)|uniprotkb:RPL11(gene name)|psi-mi:RPL11(display_short)|uniprotkb:CLL-associated antigen KW-12(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000966.2|refseq:NP_001186731.1|ensembl:ENSG00000142676(gene)|ensembl:ENST00000643754(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006605"(protein targeting)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR002132(Ribosomal protein L5)|interpro:IPR020929|interpro:IPR022803|interpro:IPR031309|interpro:IPR031310|mint:P62913|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XXB|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y6X - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P62917 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P40429 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-720205|uniprotkb:A8K505|ensembl:ENSP00000375730 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl13a_human(display_long)|uniprotkb:23 kDa highly basic protein(gene name synonym)|uniprotkb:RPL13A(gene name)|psi-mi:RPL13A(display_short)|uniprotkb:Large ribosomal subunit protein uL13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_036555.1|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|rcsb pdb:6OLF|ensembl:ENSG00000142541(gene)|ensembl:ENST00000391857(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1901194"(negative regulation of formation of translation preinitiation complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005755(Ribosomal protein L13, eukaryotic/archaeal)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR023563|interpro:IPR036899|mint:P40429|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|refseq:NP_001257420.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:pcKDTEBZXxtm1MAH+4nv0p3PqFs9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9HCE1 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P18124 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q6UXN9 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q02878 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q07020 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352694|intact:EBI-8456577|intact:MINT-8429255|uniprotkb:F8VWC5|uniprotkb:Q8WTZ6|ensembl:ENSP00000447001 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl18_human(display_long)|uniprotkb:RPL18(gene name)|psi-mi:RPL18(display_short)|uniprotkb:Large ribosomal subunit protein eL18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000970.1|ensembl:ENSG00000063177(gene)|ensembl:ENST00000549920(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000039(Ribosomal protein L18e)|interpro:IPR021131|interpro:IPR021132|interpro:IPR036227|mint:Q07020|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001257419.1 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:GgzBcLEQgBqbApFlaQIU2jktkAE9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P30050 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-352743|uniprotkb:Q6PB27|uniprotkb:Q5VVV2|ensembl:ENSP00000354739 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl12_human(display_long)|uniprotkb:RPL12(gene name)|psi-mi:RPL12(display_short)|uniprotkb:Large ribosomal subunit protein uL11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000967.1|ensembl:ENSG00000197958(gene)|ensembl:ENST00000361436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P30050|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:TNPEtl60cILofaPzUznvZiw6D7E9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P46779 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-366357|uniprotkb:Q6IAY0|uniprotkb:Q96FX1|uniprotkb:Q9BWQ0|uniprotkb:B2R4A6|uniprotkb:B4DEP9|uniprotkb:E9PB24|uniprotkb:C9JB50|uniprotkb:G5E9L2|ensembl:ENSP00000342787|ensembl:ENSP00000453319 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl28_human(display_long)|uniprotkb:RPL28(gene name)|psi-mi:RPL28(display_short)|uniprotkb:Large ribosomal subunit protein eL28(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001129608.1|refseq:NP_001129609.1|refseq:NP_000982.2|refseq:NP_001129606.1|refseq:NP_001129607.1|ensembl:ENSG00000108107(gene)|ensembl:ENST00000344063(transcript)|ensembl:ENST00000559463(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002672(Ribosomal protein L28e)|interpro:IPR029004|mint:P46779|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:I7Me1zjfxk98g6C2NoYOWlmrYVc9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:P05386 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q9GZT8 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14684 uniprotkb:Q02543 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 intact:EBI-350523|ensembl:ENSP00000222247 psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:rl18a_human(display_long)|uniprotkb:RPL18A(gene name)|psi-mi:RPL18A(display_short)|uniprotkb:Large ribosomal subunit protein eL20(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16686997|imex:IM-26310-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 refseq:NP_000971.1|interpro:IPR021138|interpro:IPR023573|interpro:IPR028877|mint:Q02543|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|go:"GO:0097327"(response to antineoplastic agent)|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|ensembl:ENSG00000105640(gene)|ensembl:ENST00000222247(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|rcsb pdb:6ZME|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Figure 6, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2021/11/30 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rogid:O9XdW7Let2GcJpJLVuUtatVVv1I9606 rigid:1Chu5KM6dZNHKsmGdDRkaKbul0I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36873 uniprotkb:Q14684 intact:EBI-356283|ensembl:ENSP00000335084 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym) psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Chamousset et al. (2010) imex:IM-26310|pubmed:20926688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16687463|imex:IM-26310-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 go:"GO:0005634"(nucleus) - - figure legend:Fig 7D|comment:RRP1B is found only in the pre-60S fraction not the pre-40S fraction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/10/19 2017/12/08 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rigid:HYF3dsivfyAxVKoKd2qnrO39K+I false - green fluorescent protein tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)