#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9JJP2	uniprotkb:P23804	intact:EBI-1770138|intact:EBI-1770168|uniprotkb:B1AX89|uniprotkb:B1AX90|uniprotkb:Q3UT91|uniprotkb:Q9CU77|uniprotkb:Q9JJP1|uniprotkb:Q9WUJ0|ensembl:ENSMUSP00000101269	intact:EBI-641788|uniprotkb:Q91XK7|uniprotkb:Q61040|uniprotkb:Q64330|ensembl:ENSMUSP00000020408	psi-mi:p73_mouse(display_long)|uniprotkb:Tp73(gene name)|psi-mi:Tp73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:Trp73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:mdm2_mouse(display_long)|uniprotkb:p53-binding protein Mdm2(gene name synonym)|uniprotkb:Oncoprotein Mdm2(gene name synonym)|uniprotkb:Double minute 2 protein(gene name synonym)|uniprotkb:Mdm2(gene name)|psi-mi:Mdm2(display_short)|uniprotkb:RING-type E3 ubiquitin transferase Mdm2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Busuttil et al. (2010)	pubmed:20921405|doi:10.1073/pnas.1006163107|imex:IM-16503	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15882515|imex:IM-16503-1|dip:DIP-187757E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119802.1|refseq:NP_001119803.1|refseq:NP_035772.2|dip:DIP-41942N|ensembl:ENSMUSG00000029026(gene)|ensembl:ENSMUST00000105644(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030054"(cell junction)|go:"GO:0030900"(forebrain development)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:Q9JJP2|reactome:R-MMU-6804759|reactome:R-MMU-8939236	refseq:NP_034916.1|dip:DIP-24174N|dip:DIP-24196N|refseq:NP_001275515.1|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043278"(response to morphine)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045472"(response to ether)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0071301"(cellular response to vitamin B1)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904404"(response to formaldehyde)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990785"(response to water-immersion restraint stress)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015459(Ubiquitin-protein ligase E3 MDM2)|interpro:IPR016495(p53 negative regulator Mdm2/Mdm4)|interpro:IPR028340|interpro:IPR036443|interpro:IPR036885|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR044080|mint:P23804|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|reactome:R-MMU-198323|reactome:R-MMU-2559580|reactome:R-MMU-2559585|reactome:R-MMU-3232142|reactome:R-MMU-399719|reactome:R-MMU-5689880|reactome:R-MMU-6804756|reactome:R-MMU-6804757|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051726"(regulation of cell cycle)|reactome:R-MMU-6804760|reactome:R-MMU-69541|reactome:R-MMU-8941858|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070301"(cellular response to hydrogen peroxide)|ensembl:ENSMUSG00000020184(gene)|ensembl:ENSMUST00000020408(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001568"(blood vessel development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002039"(p53 binding)|go:"GO:0003170"(heart valve development)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010039"(response to iron ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0010977"(negative regulation of neuron projection development)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/06	2017/08/10	rogid:XUKqmk0uMp4NvED+uCHZJ+XzunQ10090	rogid:iXyzJNF2in1Qj+lXPmfZMlKWgls10090	rigid:/PYUbrt4esn3qCyLxCxEOOYoC08	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)