#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O35464-1 uniprotkb:O35464-1 intact:EBI-15880936|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442 intact:EBI-15880936|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442 psi-mi:o35464-1(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:o35464-1(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15880947|imex:IM-16272-2|dip:DIP-187390E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8057848(isoform-parent)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript) intact:EBI-8057848(isoform-parent)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090 rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090 rigid:wHqEfMSEJtqGSB4UN9lgQNufdlg false binding-associated region:19-571 binding-associated region:19-571 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92854-1 uniprotkb:O43157-1 intact:EBI-15880903|ensembl:ENSP00000348822|ensembl:ENSP00000388768|ensembl:ENSP00000405102|ensembl:ENSP00000416523 intact:EBI-15880891|ensembl:ENSP00000296440|ensembl:ENSP00000351338 psi-mi:q92854-1(display_long)|uniprotkb:SEMA4D(gene name)|psi-mi:SEMA4D(display_short)|uniprotkb:C9orf164(gene name synonym)|uniprotkb:CD100(gene name synonym)|uniprotkb:SEMAJ(gene name synonym)|uniprotkb:A8(gene name synonym)|uniprotkb:BB18(gene name synonym)|uniprotkb:GR3(gene name synonym) psi-mi:o43157-1(display_long)|uniprotkb:PLXNB1(gene name)|psi-mi:PLXNB1(display_short)|uniprotkb:KIAA0407(gene name synonym)|uniprotkb:PLXN5(gene name synonym)|uniprotkb:SEP(gene name synonym)|uniprotkb:Semaphorin receptor SEP(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15880914|imex:IM-16272-1|dip:DIP-187387E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2855119(isoform-parent)|ensembl:ENSG00000187764(gene)|ensembl:ENST00000356444(transcript)|ensembl:ENST00000422704(transcript)|ensembl:ENST00000438547(transcript)|ensembl:ENST00000450295(transcript) ensembl:ENSG00000164050(gene)|ensembl:ENST00000358536(transcript)|ensembl:ENST00000296440(transcript)|intact:EBI-1111488(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:2Xa00fuwt0CCvnzXwe5Q0ukApRc9606 rogid:wWC3lipQ3PIBCvCjt5t2gQTAXro9606 rigid:IxQJ+SM2F98S9hQFoXImGXKWEig false binding-associated region:22-677 binding-associated region:20-535 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92854-1 uniprotkb:Q92854-1 intact:EBI-15880903|ensembl:ENSP00000348822|ensembl:ENSP00000388768|ensembl:ENSP00000405102|ensembl:ENSP00000416523 intact:EBI-15880903|ensembl:ENSP00000348822|ensembl:ENSP00000388768|ensembl:ENSP00000405102|ensembl:ENSP00000416523 psi-mi:q92854-1(display_long)|uniprotkb:SEMA4D(gene name)|psi-mi:SEMA4D(display_short)|uniprotkb:C9orf164(gene name synonym)|uniprotkb:CD100(gene name synonym)|uniprotkb:SEMAJ(gene name synonym)|uniprotkb:A8(gene name synonym)|uniprotkb:BB18(gene name synonym)|uniprotkb:GR3(gene name synonym) psi-mi:q92854-1(display_long)|uniprotkb:SEMA4D(gene name)|psi-mi:SEMA4D(display_short)|uniprotkb:C9orf164(gene name synonym)|uniprotkb:CD100(gene name synonym)|uniprotkb:SEMAJ(gene name synonym)|uniprotkb:A8(gene name synonym)|uniprotkb:BB18(gene name synonym)|uniprotkb:GR3(gene name synonym) psi-mi:"MI:0067"(light scattering) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15880965|imex:IM-16272-3|dip:DIP-187389E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2855119(isoform-parent)|ensembl:ENSG00000187764(gene)|ensembl:ENST00000356444(transcript)|ensembl:ENST00000422704(transcript)|ensembl:ENST00000438547(transcript)|ensembl:ENST00000450295(transcript) intact:EBI-2855119(isoform-parent)|ensembl:ENSG00000187764(gene)|ensembl:ENST00000356444(transcript)|ensembl:ENST00000422704(transcript)|ensembl:ENST00000438547(transcript)|ensembl:ENST00000450295(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:2Xa00fuwt0CCvnzXwe5Q0ukApRc9606 rogid:2Xa00fuwt0CCvnzXwe5Q0ukApRc9606 rigid:ZEpT1RShAUNVQImLfAHPaj0iePk false binding-associated region:22-677|mutation disrupting interaction:246-246,244-244 binding-associated region:22-677|mutation disrupting interaction:246-246,244-244 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92854-1 uniprotkb:O43157-1 intact:EBI-15880903|ensembl:ENSP00000348822|ensembl:ENSP00000388768|ensembl:ENSP00000405102|ensembl:ENSP00000416523 intact:EBI-15880891|ensembl:ENSP00000296440|ensembl:ENSP00000351338 psi-mi:q92854-1(display_long)|uniprotkb:SEMA4D(gene name)|psi-mi:SEMA4D(display_short)|uniprotkb:C9orf164(gene name synonym)|uniprotkb:CD100(gene name synonym)|uniprotkb:SEMAJ(gene name synonym)|uniprotkb:A8(gene name synonym)|uniprotkb:BB18(gene name synonym)|uniprotkb:GR3(gene name synonym) psi-mi:o43157-1(display_long)|uniprotkb:PLXNB1(gene name)|psi-mi:PLXNB1(display_short)|uniprotkb:KIAA0407(gene name synonym)|uniprotkb:PLXN5(gene name synonym)|uniprotkb:SEP(gene name synonym)|uniprotkb:Semaphorin receptor SEP(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15880987|imex:IM-16272-4|dip:DIP-187387E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2855119(isoform-parent)|ensembl:ENSG00000187764(gene)|ensembl:ENST00000356444(transcript)|ensembl:ENST00000422704(transcript)|ensembl:ENST00000438547(transcript)|ensembl:ENST00000450295(transcript) ensembl:ENSG00000164050(gene)|ensembl:ENST00000358536(transcript)|ensembl:ENST00000296440(transcript)|intact:EBI-1111488(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:2Xa00fuwt0CCvnzXwe5Q0ukApRc9606 rogid:wWC3lipQ3PIBCvCjt5t2gQTAXro9606 rigid:IxQJ+SM2F98S9hQFoXImGXKWEig false binding-associated region:22-677 binding-associated region:20-535 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35464-1 uniprotkb:O35464-1 intact:EBI-15880936|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442 intact:EBI-15880936|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442 psi-mi:o35464-1(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:o35464-1(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:"MI:0067"(light scattering) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15881008|imex:IM-16272-5|dip:DIP-187390E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8057848(isoform-parent)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript) intact:EBI-8057848(isoform-parent)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090 rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090 rigid:wHqEfMSEJtqGSB4UN9lgQNufdlg false binding-associated region:19-571 binding-associated region:19-571 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70207 uniprotkb:O35464-1 intact:EBI-771272|uniprotkb:Q6NVE6|uniprotkb:Q6PHN4|uniprotkb:Q80TZ7|uniprotkb:Q8R1I4|ensembl:ENSMUSP00000027952 intact:EBI-15880936|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442 psi-mi:plxa2_mouse(display_long)|uniprotkb:Plxna2(gene name)|psi-mi:Plxna2(display_short)|uniprotkb:Kiaa0463(gene name synonym) psi-mi:o35464-1(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15881028|imex:IM-16272-6|dip:DIP-187388E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032908.2|dip:DIP-32252N|ensembl:ENSMUSG00000026640(gene)|ensembl:ENSMUST00000027952(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021915"(neural tube development)|go:"GO:0021935"(cerebellar granule cell precursor tangential migration)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060174"(limb bud formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|interpro:IPR042826|rcsb pdb:3AL8|rcsb pdb:3AL9|rcsb pdb:3OKT|rcsb pdb:3OKY|rcsb pdb:4GZA|rcsb pdb:5L5G|rcsb pdb:5L74|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956 intact:EBI-8057848(isoform-parent)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:nzfx1kD2CVYGymwROVFeLEby09E10090 rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090 rigid:nb7R1lYC/4z+SwhD/OzjUCUtueE false binding-associated region:35-703|mutation disrupting interaction:221-221|mutation disrupting interaction:396-396 binding-associated region:19-571 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70207 uniprotkb:O35464-1 intact:EBI-771272|uniprotkb:Q6NVE6|uniprotkb:Q6PHN4|uniprotkb:Q80TZ7|uniprotkb:Q8R1I4|ensembl:ENSMUSP00000027952 intact:EBI-15880936|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442 psi-mi:plxa2_mouse(display_long)|uniprotkb:Plxna2(gene name)|psi-mi:Plxna2(display_short)|uniprotkb:Kiaa0463(gene name synonym) psi-mi:o35464-1(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15881056|imex:IM-16272-7|dip:DIP-187388E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032908.2|dip:DIP-32252N|ensembl:ENSMUSG00000026640(gene)|ensembl:ENSMUST00000027952(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021915"(neural tube development)|go:"GO:0021935"(cerebellar granule cell precursor tangential migration)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060174"(limb bud formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|interpro:IPR042826|rcsb pdb:3AL8|rcsb pdb:3AL9|rcsb pdb:3OKT|rcsb pdb:3OKY|rcsb pdb:4GZA|rcsb pdb:5L5G|rcsb pdb:5L74|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956 intact:EBI-8057848(isoform-parent)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:nzfx1kD2CVYGymwROVFeLEby09E10090 rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090 rigid:nb7R1lYC/4z+SwhD/OzjUCUtueE false binding-associated region:35-703 binding-associated region:19-571 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35464-1 uniprotkb:O35464-1 intact:EBI-15880936|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442 intact:EBI-15880936|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442 psi-mi:o35464-1(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:o35464-1(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15881077|imex:IM-16272-8|dip:DIP-187390E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8057848(isoform-parent)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript) intact:EBI-8057848(isoform-parent)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090 rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090 rigid:wHqEfMSEJtqGSB4UN9lgQNufdlg false binding-associated region:19-571 binding-associated region:19-571 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92854-1 uniprotkb:O43157-1 intact:EBI-15880903|ensembl:ENSP00000348822|ensembl:ENSP00000388768|ensembl:ENSP00000405102|ensembl:ENSP00000416523 intact:EBI-15880891|ensembl:ENSP00000296440|ensembl:ENSP00000351338 psi-mi:q92854-1(display_long)|uniprotkb:SEMA4D(gene name)|psi-mi:SEMA4D(display_short)|uniprotkb:C9orf164(gene name synonym)|uniprotkb:CD100(gene name synonym)|uniprotkb:SEMAJ(gene name synonym)|uniprotkb:A8(gene name synonym)|uniprotkb:BB18(gene name synonym)|uniprotkb:GR3(gene name synonym) psi-mi:o43157-1(display_long)|uniprotkb:PLXNB1(gene name)|psi-mi:PLXNB1(display_short)|uniprotkb:KIAA0407(gene name synonym)|uniprotkb:PLXN5(gene name synonym)|uniprotkb:SEP(gene name synonym)|uniprotkb:Semaphorin receptor SEP(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15881095|imex:IM-16272-9|dip:DIP-187387E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2855119(isoform-parent)|ensembl:ENSG00000187764(gene)|ensembl:ENST00000356444(transcript)|ensembl:ENST00000422704(transcript)|ensembl:ENST00000438547(transcript)|ensembl:ENST00000450295(transcript) ensembl:ENSG00000164050(gene)|ensembl:ENST00000358536(transcript)|ensembl:ENST00000296440(transcript)|intact:EBI-1111488(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:2Xa00fuwt0CCvnzXwe5Q0ukApRc9606 rogid:wWC3lipQ3PIBCvCjt5t2gQTAXro9606 rigid:IxQJ+SM2F98S9hQFoXImGXKWEig false binding-associated region:22-677|mutation disrupting interaction:182-182,181-181|mutation disrupting interaction:101-101,100-100 binding-associated region:20-535 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92854-1 uniprotkb:Q92854-1 intact:EBI-15880903|ensembl:ENSP00000348822|ensembl:ENSP00000388768|ensembl:ENSP00000405102|ensembl:ENSP00000416523 intact:EBI-15880903|ensembl:ENSP00000348822|ensembl:ENSP00000388768|ensembl:ENSP00000405102|ensembl:ENSP00000416523 psi-mi:q92854-1(display_long)|uniprotkb:SEMA4D(gene name)|psi-mi:SEMA4D(display_short)|uniprotkb:C9orf164(gene name synonym)|uniprotkb:CD100(gene name synonym)|uniprotkb:SEMAJ(gene name synonym)|uniprotkb:A8(gene name synonym)|uniprotkb:BB18(gene name synonym)|uniprotkb:GR3(gene name synonym) psi-mi:q92854-1(display_long)|uniprotkb:SEMA4D(gene name)|psi-mi:SEMA4D(display_short)|uniprotkb:C9orf164(gene name synonym)|uniprotkb:CD100(gene name synonym)|uniprotkb:SEMAJ(gene name synonym)|uniprotkb:A8(gene name synonym)|uniprotkb:BB18(gene name synonym)|uniprotkb:GR3(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15881124|imex:IM-16272-10|dip:DIP-187389E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2855119(isoform-parent)|ensembl:ENSG00000187764(gene)|ensembl:ENST00000356444(transcript)|ensembl:ENST00000422704(transcript)|ensembl:ENST00000438547(transcript)|ensembl:ENST00000450295(transcript) intact:EBI-2855119(isoform-parent)|ensembl:ENSG00000187764(gene)|ensembl:ENST00000356444(transcript)|ensembl:ENST00000422704(transcript)|ensembl:ENST00000438547(transcript)|ensembl:ENST00000450295(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:2Xa00fuwt0CCvnzXwe5Q0ukApRc9606 rogid:2Xa00fuwt0CCvnzXwe5Q0ukApRc9606 rigid:ZEpT1RShAUNVQImLfAHPaj0iePk false binding-associated region:22-677|mutation disrupting interaction:246-246,244-244 binding-associated region:22-677|mutation disrupting interaction:246-246,244-244 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70207 uniprotkb:P70207 intact:EBI-771272|uniprotkb:Q6NVE6|uniprotkb:Q6PHN4|uniprotkb:Q80TZ7|uniprotkb:Q8R1I4|ensembl:ENSMUSP00000027952 intact:EBI-771272|uniprotkb:Q6NVE6|uniprotkb:Q6PHN4|uniprotkb:Q80TZ7|uniprotkb:Q8R1I4|ensembl:ENSMUSP00000027952 psi-mi:plxa2_mouse(display_long)|uniprotkb:Plxna2(gene name)|psi-mi:Plxna2(display_short)|uniprotkb:Kiaa0463(gene name synonym) psi-mi:plxa2_mouse(display_long)|uniprotkb:Plxna2(gene name)|psi-mi:Plxna2(display_short)|uniprotkb:Kiaa0463(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15881146|imex:IM-16272-11|dip:DIP-187391E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032908.2|dip:DIP-32252N|ensembl:ENSMUSG00000026640(gene)|ensembl:ENSMUST00000027952(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021915"(neural tube development)|go:"GO:0021935"(cerebellar granule cell precursor tangential migration)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060174"(limb bud formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|interpro:IPR042826|rcsb pdb:3AL8|rcsb pdb:3AL9|rcsb pdb:3OKT|rcsb pdb:3OKY|rcsb pdb:4GZA|rcsb pdb:5L5G|rcsb pdb:5L74|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956 refseq:NP_032908.2|dip:DIP-32252N|ensembl:ENSMUSG00000026640(gene)|ensembl:ENSMUST00000027952(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021915"(neural tube development)|go:"GO:0021935"(cerebellar granule cell precursor tangential migration)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060174"(limb bud formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|interpro:IPR042826|rcsb pdb:3AL8|rcsb pdb:3AL9|rcsb pdb:3OKT|rcsb pdb:3OKY|rcsb pdb:4GZA|rcsb pdb:5L5G|rcsb pdb:5L74|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:nzfx1kD2CVYGymwROVFeLEby09E10090 rogid:nzfx1kD2CVYGymwROVFeLEby09E10090 rigid:XbChKD3EUXy8rr2UWnQrV+Q5fuQ false sufficient binding region:35-1040 sufficient binding region:35-1040 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92854-1 uniprotkb:Q92854-1 intact:EBI-15880903|ensembl:ENSP00000348822|ensembl:ENSP00000388768|ensembl:ENSP00000405102|ensembl:ENSP00000416523 intact:EBI-15880903|ensembl:ENSP00000348822|ensembl:ENSP00000388768|ensembl:ENSP00000405102|ensembl:ENSP00000416523 psi-mi:q92854-1(display_long)|uniprotkb:SEMA4D(gene name)|psi-mi:SEMA4D(display_short)|uniprotkb:C9orf164(gene name synonym)|uniprotkb:CD100(gene name synonym)|uniprotkb:SEMAJ(gene name synonym)|uniprotkb:A8(gene name synonym)|uniprotkb:BB18(gene name synonym)|uniprotkb:GR3(gene name synonym) psi-mi:q92854-1(display_long)|uniprotkb:SEMA4D(gene name)|psi-mi:SEMA4D(display_short)|uniprotkb:C9orf164(gene name synonym)|uniprotkb:CD100(gene name synonym)|uniprotkb:SEMAJ(gene name synonym)|uniprotkb:A8(gene name synonym)|uniprotkb:BB18(gene name synonym)|uniprotkb:GR3(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15881164|imex:IM-16272-12|dip:DIP-187389E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2855119(isoform-parent)|ensembl:ENSG00000187764(gene)|ensembl:ENST00000356444(transcript)|ensembl:ENST00000422704(transcript)|ensembl:ENST00000438547(transcript)|ensembl:ENST00000450295(transcript) intact:EBI-2855119(isoform-parent)|ensembl:ENSG00000187764(gene)|ensembl:ENST00000356444(transcript)|ensembl:ENST00000422704(transcript)|ensembl:ENST00000438547(transcript)|ensembl:ENST00000450295(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:2Xa00fuwt0CCvnzXwe5Q0ukApRc9606 rogid:2Xa00fuwt0CCvnzXwe5Q0ukApRc9606 rigid:ZEpT1RShAUNVQImLfAHPaj0iePk false binding-associated region:22-677|mutation disrupting interaction:246-246,244-244 binding-associated region:22-677|mutation disrupting interaction:246-246,244-244 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70207 uniprotkb:P70207 intact:EBI-771272|uniprotkb:Q6NVE6|uniprotkb:Q6PHN4|uniprotkb:Q80TZ7|uniprotkb:Q8R1I4|ensembl:ENSMUSP00000027952 intact:EBI-771272|uniprotkb:Q6NVE6|uniprotkb:Q6PHN4|uniprotkb:Q80TZ7|uniprotkb:Q8R1I4|ensembl:ENSMUSP00000027952 psi-mi:plxa2_mouse(display_long)|uniprotkb:Plxna2(gene name)|psi-mi:Plxna2(display_short)|uniprotkb:Kiaa0463(gene name synonym) psi-mi:plxa2_mouse(display_long)|uniprotkb:Plxna2(gene name)|psi-mi:Plxna2(display_short)|uniprotkb:Kiaa0463(gene name synonym) psi-mi:"MI:0067"(light scattering) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15881210|imex:IM-16272-14|dip:DIP-187391E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032908.2|dip:DIP-32252N|ensembl:ENSMUSG00000026640(gene)|ensembl:ENSMUST00000027952(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021915"(neural tube development)|go:"GO:0021935"(cerebellar granule cell precursor tangential migration)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060174"(limb bud formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|interpro:IPR042826|rcsb pdb:3AL8|rcsb pdb:3AL9|rcsb pdb:3OKT|rcsb pdb:3OKY|rcsb pdb:4GZA|rcsb pdb:5L5G|rcsb pdb:5L74|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956 refseq:NP_032908.2|dip:DIP-32252N|ensembl:ENSMUSG00000026640(gene)|ensembl:ENSMUST00000027952(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021915"(neural tube development)|go:"GO:0021935"(cerebellar granule cell precursor tangential migration)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060174"(limb bud formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|interpro:IPR042826|rcsb pdb:3AL8|rcsb pdb:3AL9|rcsb pdb:3OKT|rcsb pdb:3OKY|rcsb pdb:4GZA|rcsb pdb:5L5G|rcsb pdb:5L74|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:nzfx1kD2CVYGymwROVFeLEby09E10090 rogid:nzfx1kD2CVYGymwROVFeLEby09E10090 rigid:XbChKD3EUXy8rr2UWnQrV+Q5fuQ false binding-associated region:35-1231 binding-associated region:35-1231 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70207 uniprotkb:O35464-1 intact:EBI-771272|uniprotkb:Q6NVE6|uniprotkb:Q6PHN4|uniprotkb:Q80TZ7|uniprotkb:Q8R1I4|ensembl:ENSMUSP00000027952 intact:EBI-15880936|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442 psi-mi:plxa2_mouse(display_long)|uniprotkb:Plxna2(gene name)|psi-mi:Plxna2(display_short)|uniprotkb:Kiaa0463(gene name synonym) psi-mi:o35464-1(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15881186|imex:IM-16272-13|dip:DIP-187388E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032908.2|dip:DIP-32252N|ensembl:ENSMUSG00000026640(gene)|ensembl:ENSMUST00000027952(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021915"(neural tube development)|go:"GO:0021935"(cerebellar granule cell precursor tangential migration)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060174"(limb bud formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|interpro:IPR042826|rcsb pdb:3AL8|rcsb pdb:3AL9|rcsb pdb:3OKT|rcsb pdb:3OKY|rcsb pdb:4GZA|rcsb pdb:5L5G|rcsb pdb:5L74|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956 intact:EBI-8057848(isoform-parent)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:nzfx1kD2CVYGymwROVFeLEby09E10090 rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090 rigid:nb7R1lYC/4z+SwhD/OzjUCUtueE false binding-associated region:35-703 binding-associated region:19-571|mutation decreasing interaction:191-191 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35464-1 uniprotkb:O35464-1 intact:EBI-15880936|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442 intact:EBI-15880936|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442 psi-mi:o35464-1(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:o35464-1(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Janssen et al. (2010) pubmed:20877282|doi:10.1038/nature09468|imex:IM-16272 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15881228|imex:IM-16272-15|dip:DIP-187390E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8057848(isoform-parent)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript) intact:EBI-8057848(isoform-parent)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090 rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090 rigid:wHqEfMSEJtqGSB4UN9lgQNufdlg false binding-associated region:19-571|mutation disrupting interaction:322-322 binding-associated region:19-571|mutation disrupting interaction:322-322 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)