#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99LI8 uniprotkb:O88689-1 intact:EBI-2119135|uniprotkb:Q61691|uniprotkb:Q8BQW3|ensembl:ENSMUSP00000101811 intact:EBI-15880299|ensembl:ENSMUSP00000141408 psi-mi:hgs_mouse(display_long)|uniprotkb:Hgs(gene name)|psi-mi:Hgs(display_short)|uniprotkb:Hrs(gene name synonym) psi-mi:o88689-1(display_long)|uniprotkb:Pcdha4(gene name)|psi-mi:Pcdha4(display_short)|uniprotkb:Cnr1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Buchanan et al. (2010) pubmed:20876099|doi:10.1073/pnas.1013105107|imex:IM-17468 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15880349|imex:IM-17468-2|dip:DIP-188635E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152800.1|refseq:NP_032270.3|dip:DIP-29102N|ensembl:ENSMUSG00000025793(gene)|ensembl:ENSMUST00000106205(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|reactome:R-MMU-182971|reactome:R-MMU-432720|reactome:R-MMU-5689880|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013420|reactome:R-MMU-917729|reactome:R-MMU-9706019 ensembl:ENSMUSG00000104252(gene)|ensembl:ENSMUST00000192512(transcript)|intact:EBI-16355484(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:FS8KSHYryqJPQyo6wRWGNz86/kw10090 rogid:nNJu0496S7I6JHdjMU7bxWwIDTY10090 rigid:gA/CQwxm8t6liPjB1tiVPyMqK18 false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q91VD8 uniprotkb:O88689-1 intact:EBI-15880305|ensembl:ENSMUSP00000055072 intact:EBI-15880299|ensembl:ENSMUSP00000141408 psi-mi:q91vd8_mouse(display_long)|uniprotkb:Pcdhb17(gene name)|psi-mi:Pcdhb17(display_short) psi-mi:o88689-1(display_long)|uniprotkb:Pcdha4(gene name)|psi-mi:Pcdha4(display_short)|uniprotkb:Cnr1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Buchanan et al. (2010) pubmed:20876099|doi:10.1073/pnas.1013105107|imex:IM-17468 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15880328|imex:IM-17468-1|dip:DIP-188634E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000046387(gene)|ensembl:ENSMUST00000053856(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|interpro:IPR002126(Cadherin)|interpro:IPR010221(VCBS)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR032455|refseq:NP_444372.2|dip:DIP-59561N ensembl:ENSMUSG00000104252(gene)|ensembl:ENSMUST00000192512(transcript)|intact:EBI-16355484(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:GmQ9nRthvyFiJeyqYCMCeOfU20E10090 rogid:nNJu0496S7I6JHdjMU7bxWwIDTY10090 rigid:5NwLSPTaNBe1FXcrUY9E45XOStk false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99LI8 uniprotkb:O88689-1 intact:EBI-2119135|uniprotkb:Q61691|uniprotkb:Q8BQW3|ensembl:ENSMUSP00000101811 intact:EBI-15880299|ensembl:ENSMUSP00000141408 psi-mi:hgs_mouse(display_long)|uniprotkb:Hgs(gene name)|psi-mi:Hgs(display_short)|uniprotkb:Hrs(gene name synonym) psi-mi:o88689-1(display_long)|uniprotkb:Pcdha4(gene name)|psi-mi:Pcdha4(display_short)|uniprotkb:Cnr1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Buchanan et al. (2010) pubmed:20876099|doi:10.1073/pnas.1013105107|imex:IM-17468 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15880370|imex:IM-17468-3|dip:DIP-188635E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152800.1|refseq:NP_032270.3|dip:DIP-29102N|ensembl:ENSMUSG00000025793(gene)|ensembl:ENSMUST00000106205(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|reactome:R-MMU-182971|reactome:R-MMU-432720|reactome:R-MMU-5689880|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013420|reactome:R-MMU-917729|reactome:R-MMU-9706019 ensembl:ENSMUSG00000104252(gene)|ensembl:ENSMUST00000192512(transcript)|intact:EBI-16355484(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:FS8KSHYryqJPQyo6wRWGNz86/kw10090 rogid:nNJu0496S7I6JHdjMU7bxWwIDTY10090 rigid:gA/CQwxm8t6liPjB1tiVPyMqK18 false - flag tag:?-?|sufficient binding region:566-947 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)