#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00004	uniprotkb:P00004	intact:EBI-865260	intact:EBI-865260	psi-mi:cyc_horse(display_long)|uniprotkb:CYCS(gene name)|psi-mi:CYCS(display_short)|uniprotkb:CYC(gene name synonym)	psi-mi:cyc_horse(display_long)|uniprotkb:CYCS(gene name)|psi-mi:CYCS(display_short)|uniprotkb:CYC(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hirota et al. (2010)	pubmed:20615990|doi:10.1073/pnas.1001839107|imex:IM-16446	taxid:9796(horse)|taxid:9796("Equus caballus (Horse)")	taxid:9796(horse)|taxid:9796("Equus caballus (Horse)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15864187|imex:IM-16446-1|dip:DIP-187675E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-36774N|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006915"(apoptotic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|go:"GO:0070469"(respirasome)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|rcsb pdb:1AKK|rcsb pdb:1CRC|rcsb pdb:1FI7|rcsb pdb:1FI9|rcsb pdb:1GIW|rcsb pdb:1HRC|rcsb pdb:1I5T|rcsb pdb:1LC1|rcsb pdb:1LC2|rcsb pdb:1M60|rcsb pdb:1OCD|rcsb pdb:1U75|rcsb pdb:1WEJ|rcsb pdb:2FRC|rcsb pdb:2GIW|rcsb pdb:2N3B|rcsb pdb:2PCB|rcsb pdb:3JBT|rcsb pdb:3NBS|rcsb pdb:3NBT|rcsb pdb:3O1Y|rcsb pdb:3O20|rcsb pdb:3WC8|rcsb pdb:3WUI|rcsb pdb:4NFG|rcsb pdb:4RSZ|rcsb pdb:5IY5|rcsb pdb:5WVE|rcsb pdb:5ZKV|rcsb pdb:6K9I|rcsb pdb:6K9J|rcsb pdb:6SUV	dip:DIP-36774N|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006915"(apoptotic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|go:"GO:0070469"(respirasome)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|rcsb pdb:1AKK|rcsb pdb:1CRC|rcsb pdb:1FI7|rcsb pdb:1FI9|rcsb pdb:1GIW|rcsb pdb:1HRC|rcsb pdb:1I5T|rcsb pdb:1LC1|rcsb pdb:1LC2|rcsb pdb:1M60|rcsb pdb:1OCD|rcsb pdb:1U75|rcsb pdb:1WEJ|rcsb pdb:2FRC|rcsb pdb:2GIW|rcsb pdb:2N3B|rcsb pdb:2PCB|rcsb pdb:3JBT|rcsb pdb:3NBS|rcsb pdb:3NBT|rcsb pdb:3O1Y|rcsb pdb:3O20|rcsb pdb:3WC8|rcsb pdb:3WUI|rcsb pdb:4NFG|rcsb pdb:4RSZ|rcsb pdb:5IY5|rcsb pdb:5WVE|rcsb pdb:5ZKV|rcsb pdb:6K9I|rcsb pdb:6K9J|rcsb pdb:6SUV	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:rr0R4M6Q4s825u6AM3R9C6CEHos9796	rogid:rr0R4M6Q4s825u6AM3R9C6CEHos9796	rigid:Ag8wZOCjPL1V50DYZBa8lHsvNFY	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00004	uniprotkb:P00004	intact:EBI-865260	intact:EBI-865260	psi-mi:cyc_horse(display_long)|uniprotkb:CYCS(gene name)|psi-mi:CYCS(display_short)|uniprotkb:CYC(gene name synonym)	psi-mi:cyc_horse(display_long)|uniprotkb:CYCS(gene name)|psi-mi:CYCS(display_short)|uniprotkb:CYC(gene name synonym)	psi-mi:"MI:0826"(x ray scattering)	Hirota et al. (2010)	pubmed:20615990|doi:10.1073/pnas.1001839107|imex:IM-16446	taxid:9796(horse)|taxid:9796("Equus caballus (Horse)")	taxid:9796(horse)|taxid:9796("Equus caballus (Horse)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15864203|imex:IM-16446-2|dip:DIP-187675E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-36774N|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006915"(apoptotic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|go:"GO:0070469"(respirasome)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|rcsb pdb:1AKK|rcsb pdb:1CRC|rcsb pdb:1FI7|rcsb pdb:1FI9|rcsb pdb:1GIW|rcsb pdb:1HRC|rcsb pdb:1I5T|rcsb pdb:1LC1|rcsb pdb:1LC2|rcsb pdb:1M60|rcsb pdb:1OCD|rcsb pdb:1U75|rcsb pdb:1WEJ|rcsb pdb:2FRC|rcsb pdb:2GIW|rcsb pdb:2N3B|rcsb pdb:2PCB|rcsb pdb:3JBT|rcsb pdb:3NBS|rcsb pdb:3NBT|rcsb pdb:3O1Y|rcsb pdb:3O20|rcsb pdb:3WC8|rcsb pdb:3WUI|rcsb pdb:4NFG|rcsb pdb:4RSZ|rcsb pdb:5IY5|rcsb pdb:5WVE|rcsb pdb:5ZKV|rcsb pdb:6K9I|rcsb pdb:6K9J|rcsb pdb:6SUV	dip:DIP-36774N|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006915"(apoptotic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|go:"GO:0070469"(respirasome)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|rcsb pdb:1AKK|rcsb pdb:1CRC|rcsb pdb:1FI7|rcsb pdb:1FI9|rcsb pdb:1GIW|rcsb pdb:1HRC|rcsb pdb:1I5T|rcsb pdb:1LC1|rcsb pdb:1LC2|rcsb pdb:1M60|rcsb pdb:1OCD|rcsb pdb:1U75|rcsb pdb:1WEJ|rcsb pdb:2FRC|rcsb pdb:2GIW|rcsb pdb:2N3B|rcsb pdb:2PCB|rcsb pdb:3JBT|rcsb pdb:3NBS|rcsb pdb:3NBT|rcsb pdb:3O1Y|rcsb pdb:3O20|rcsb pdb:3WC8|rcsb pdb:3WUI|rcsb pdb:4NFG|rcsb pdb:4RSZ|rcsb pdb:5IY5|rcsb pdb:5WVE|rcsb pdb:5ZKV|rcsb pdb:6K9I|rcsb pdb:6K9J|rcsb pdb:6SUV	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:rr0R4M6Q4s825u6AM3R9C6CEHos9796	rogid:rr0R4M6Q4s825u6AM3R9C6CEHos9796	rigid:Ag8wZOCjPL1V50DYZBa8lHsvNFY	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00004	uniprotkb:P00004	intact:EBI-865260	intact:EBI-865260	psi-mi:cyc_horse(display_long)|uniprotkb:CYCS(gene name)|psi-mi:CYCS(display_short)|uniprotkb:CYC(gene name synonym)	psi-mi:cyc_horse(display_long)|uniprotkb:CYCS(gene name)|psi-mi:CYCS(display_short)|uniprotkb:CYC(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Hirota et al. (2010)	pubmed:20615990|doi:10.1073/pnas.1001839107|imex:IM-16446	taxid:9796(horse)|taxid:9796("Equus caballus (Horse)")	taxid:9796(horse)|taxid:9796("Equus caballus (Horse)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15864221|imex:IM-16446-3|dip:DIP-187675E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-36774N|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006915"(apoptotic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|go:"GO:0070469"(respirasome)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|rcsb pdb:1AKK|rcsb pdb:1CRC|rcsb pdb:1FI7|rcsb pdb:1FI9|rcsb pdb:1GIW|rcsb pdb:1HRC|rcsb pdb:1I5T|rcsb pdb:1LC1|rcsb pdb:1LC2|rcsb pdb:1M60|rcsb pdb:1OCD|rcsb pdb:1U75|rcsb pdb:1WEJ|rcsb pdb:2FRC|rcsb pdb:2GIW|rcsb pdb:2N3B|rcsb pdb:2PCB|rcsb pdb:3JBT|rcsb pdb:3NBS|rcsb pdb:3NBT|rcsb pdb:3O1Y|rcsb pdb:3O20|rcsb pdb:3WC8|rcsb pdb:3WUI|rcsb pdb:4NFG|rcsb pdb:4RSZ|rcsb pdb:5IY5|rcsb pdb:5WVE|rcsb pdb:5ZKV|rcsb pdb:6K9I|rcsb pdb:6K9J|rcsb pdb:6SUV	dip:DIP-36774N|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006915"(apoptotic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|go:"GO:0070469"(respirasome)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|rcsb pdb:1AKK|rcsb pdb:1CRC|rcsb pdb:1FI7|rcsb pdb:1FI9|rcsb pdb:1GIW|rcsb pdb:1HRC|rcsb pdb:1I5T|rcsb pdb:1LC1|rcsb pdb:1LC2|rcsb pdb:1M60|rcsb pdb:1OCD|rcsb pdb:1U75|rcsb pdb:1WEJ|rcsb pdb:2FRC|rcsb pdb:2GIW|rcsb pdb:2N3B|rcsb pdb:2PCB|rcsb pdb:3JBT|rcsb pdb:3NBS|rcsb pdb:3NBT|rcsb pdb:3O1Y|rcsb pdb:3O20|rcsb pdb:3WC8|rcsb pdb:3WUI|rcsb pdb:4NFG|rcsb pdb:4RSZ|rcsb pdb:5IY5|rcsb pdb:5WVE|rcsb pdb:5ZKV|rcsb pdb:6K9I|rcsb pdb:6K9J|rcsb pdb:6SUV	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:rr0R4M6Q4s825u6AM3R9C6CEHos9796	rogid:rr0R4M6Q4s825u6AM3R9C6CEHos9796	rigid:Ag8wZOCjPL1V50DYZBa8lHsvNFY	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)