#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q3TKT4 uniprotkb:O09106 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 intact:EBI-301912|uniprotkb:P97476|ensembl:ENSMUSP00000099657 psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:hdac1_mouse(display_long)|uniprotkb:Hdac1(gene name)|psi-mi:Hdac1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862434|imex:IM-16302-2|dip:DIP-187457E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 dip:DIP-31499N|ensembl:ENSMUSG00000028800(gene)|ensembl:ENSMUST00000102597(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_032254.1|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O09106|reactome:R-MMU-1538133|reactome:R-MMU-201722|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-3769402|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8936459|reactome:R-MMU-8943724|reactome:R-MMU-9018519|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0001046"(core promoter sequence-specific DNA binding) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rogid:P7QV++FiMiNcabUkswbnNhGVU3410090 rigid:upYTMK7Z8TBPO88rhYy7tpDlraM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3TKT4 uniprotkb:P11103 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3 psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15862451|imex:IM-16302-3|dip:DIP-187460E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090 rigid:DtdAGamNcF8ChAxNODhEDW3oLnk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q3TKT4 uniprotkb:P70288 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 intact:EBI-302251|uniprotkb:B2RRP3 psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15862451|imex:IM-16302-3|dip:DIP-187460E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rogid:bGLIDKTlyhBz40NViC8calRacZ010090 rigid:DtdAGamNcF8ChAxNODhEDW3oLnk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q3TKT4 uniprotkb:Q99N13 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 intact:EBI-645361|uniprotkb:Q4QQN7|uniprotkb:Q8R4Y6|uniprotkb:Q9EPT2 psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:hdac9_mouse(display_long)|uniprotkb:Histone deacetylase 7B(gene name synonym)|uniprotkb:Histone deacetylase-related protein(gene name synonym)|uniprotkb:MEF2-interacting transcription repressor MITR(gene name synonym)|uniprotkb:Hdac9(gene name)|psi-mi:Hdac9(display_short)|uniprotkb:Hdac7b(gene name synonym)|uniprotkb:Hdrp(gene name synonym)|uniprotkb:Mitr(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15862451|imex:IM-16302-3|dip:DIP-187460E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 refseq:NP_077038.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008340"(determination of adult lifespan)|dip:DIP-41905N|go:"GO:0016575"(histone deacetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042113"(B cell activation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0051153"(regulation of striated muscle cell differentiation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990678"(histone H4-K16 deacetylation)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR024643|rcsb pdb:1TQE psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rogid:PFLDukT41qTdipVVfoa+Ck+6A6M10090 rigid:DtdAGamNcF8ChAxNODhEDW3oLnk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q3TKT4 uniprotkb:O09106 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 intact:EBI-301912|uniprotkb:P97476|ensembl:ENSMUSP00000099657 psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:hdac1_mouse(display_long)|uniprotkb:Hdac1(gene name)|psi-mi:Hdac1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862417|imex:IM-16302-1|dip:DIP-187457E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 dip:DIP-31499N|ensembl:ENSMUSG00000028800(gene)|ensembl:ENSMUST00000102597(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_032254.1|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O09106|reactome:R-MMU-1538133|reactome:R-MMU-201722|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-3769402|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8936459|reactome:R-MMU-8943724|reactome:R-MMU-9018519|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0001046"(core promoter sequence-specific DNA binding) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rogid:P7QV++FiMiNcabUkswbnNhGVU3410090 rigid:upYTMK7Z8TBPO88rhYy7tpDlraM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70288 uniprotkb:P11103 intact:EBI-302251|uniprotkb:B2RRP3 intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3 psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym) psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15862521|imex:IM-16302-7|dip:DIP-187461E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288 go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:bGLIDKTlyhBz40NViC8calRacZ010090 rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090 rigid:9KKNb0nuQVvLwG+6CzfK4RoUqNo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70288 uniprotkb:Q3TKT4 intact:EBI-302251|uniprotkb:B2RRP3 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15862521|imex:IM-16302-7|dip:DIP-187461E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288 refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:bGLIDKTlyhBz40NViC8calRacZ010090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:9KKNb0nuQVvLwG+6CzfK4RoUqNo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11103 uniprotkb:P70288 intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3 intact:EBI-302251|uniprotkb:B2RRP3 psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862539|imex:IM-16302-8|dip:DIP-187464E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090 rogid:bGLIDKTlyhBz40NViC8calRacZ010090 rigid:abVjkYwZUsIVePY9hEgdY8If/9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88895 uniprotkb:Q3TKT4 intact:EBI-302263|uniprotkb:O88896 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:hdac3_mouse(display_long)|uniprotkb:Hdac3(gene name)|psi-mi:Hdac3(display_short) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862556|imex:IM-16302-9|dip:DIP-187465E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0051020"(GTPase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990679"(histone H4-K12 deacetylation)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564|dip:DIP-32547N|mint:O88895 refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:0dUkbfmVE49cbSiAPqrb7uFN8l010090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:um/s1Ho56ChsB/zaShLnO+AStpI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70288 uniprotkb:Q3TKT4 intact:EBI-302251|uniprotkb:B2RRP3 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862573|imex:IM-16302-10|dip:DIP-187458E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288 refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:bGLIDKTlyhBz40NViC8calRacZ010090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:dflhjrXyhxGqhuoDRloeM42uAGU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11103 uniprotkb:Q3TKT4 intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862590|imex:IM-16302-11|dip:DIP-187462E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:qt8Eyzv+zVFibgQo3dOLDhcOfk4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88895 uniprotkb:Q3TKT4 intact:EBI-302263|uniprotkb:O88896 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:hdac3_mouse(display_long)|uniprotkb:Hdac3(gene name)|psi-mi:Hdac3(display_short) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862487|imex:IM-16302-5|dip:DIP-187465E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0051020"(GTPase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990679"(histone H4-K12 deacetylation)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564|dip:DIP-32547N|mint:O88895 refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:0dUkbfmVE49cbSiAPqrb7uFN8l010090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:um/s1Ho56ChsB/zaShLnO+AStpI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11103 uniprotkb:P70288 intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3 intact:EBI-302251|uniprotkb:B2RRP3 psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862470|imex:IM-16302-4|dip:DIP-187464E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090 rogid:bGLIDKTlyhBz40NViC8calRacZ010090 rigid:abVjkYwZUsIVePY9hEgdY8If/9Q false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70288 uniprotkb:Q3TKT4 intact:EBI-302251|uniprotkb:B2RRP3 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862504|imex:IM-16302-6|dip:DIP-187458E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288 refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:bGLIDKTlyhBz40NViC8calRacZ010090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:dflhjrXyhxGqhuoDRloeM42uAGU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11103 uniprotkb:Q99N13 intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3 intact:EBI-645361|uniprotkb:Q4QQN7|uniprotkb:Q8R4Y6|uniprotkb:Q9EPT2 psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:hdac9_mouse(display_long)|uniprotkb:Histone deacetylase 7B(gene name synonym)|uniprotkb:Histone deacetylase-related protein(gene name synonym)|uniprotkb:MEF2-interacting transcription repressor MITR(gene name synonym)|uniprotkb:Hdac9(gene name)|psi-mi:Hdac9(display_short)|uniprotkb:Hdac7b(gene name synonym)|uniprotkb:Hdrp(gene name synonym)|uniprotkb:Mitr(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862624|imex:IM-16302-13|dip:DIP-187463E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N refseq:NP_077038.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008340"(determination of adult lifespan)|dip:DIP-41905N|go:"GO:0016575"(histone deacetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042113"(B cell activation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0051153"(regulation of striated muscle cell differentiation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990678"(histone H4-K16 deacetylation)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR024643|rcsb pdb:1TQE psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090 rogid:PFLDukT41qTdipVVfoa+Ck+6A6M10090 rigid:yMNl/6oADKMSfLZdyX7vDTfRpRY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99N13 uniprotkb:Q3TKT4 intact:EBI-645361|uniprotkb:Q4QQN7|uniprotkb:Q8R4Y6|uniprotkb:Q9EPT2 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:hdac9_mouse(display_long)|uniprotkb:Histone deacetylase 7B(gene name synonym)|uniprotkb:Histone deacetylase-related protein(gene name synonym)|uniprotkb:MEF2-interacting transcription repressor MITR(gene name synonym)|uniprotkb:Hdac9(gene name)|psi-mi:Hdac9(display_short)|uniprotkb:Hdac7b(gene name synonym)|uniprotkb:Hdrp(gene name synonym)|uniprotkb:Mitr(gene name synonym) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862607|imex:IM-16302-12|dip:DIP-187459E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077038.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008340"(determination of adult lifespan)|dip:DIP-41905N|go:"GO:0016575"(histone deacetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042113"(B cell activation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0051153"(regulation of striated muscle cell differentiation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990678"(histone H4-K16 deacetylation)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR024643|rcsb pdb:1TQE refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:PFLDukT41qTdipVVfoa+Ck+6A6M10090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:79+4dyrYAcmGaiXQAY4ftSpU4hY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99N13 uniprotkb:Q3TKT4 intact:EBI-645361|uniprotkb:Q4QQN7|uniprotkb:Q8R4Y6|uniprotkb:Q9EPT2 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:hdac9_mouse(display_long)|uniprotkb:Histone deacetylase 7B(gene name synonym)|uniprotkb:Histone deacetylase-related protein(gene name synonym)|uniprotkb:MEF2-interacting transcription repressor MITR(gene name synonym)|uniprotkb:Hdac9(gene name)|psi-mi:Hdac9(display_short)|uniprotkb:Hdac7b(gene name synonym)|uniprotkb:Hdrp(gene name synonym)|uniprotkb:Mitr(gene name synonym) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hang et al. (2010) pubmed:20596014|doi:10.1038/nature09130|imex:IM-16302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15862641|imex:IM-16302-14|dip:DIP-187459E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077038.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008340"(determination of adult lifespan)|dip:DIP-41905N|go:"GO:0016575"(histone deacetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042113"(B cell activation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0051153"(regulation of striated muscle cell differentiation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990678"(histone H4-K16 deacetylation)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR024643|rcsb pdb:1TQE refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:PFLDukT41qTdipVVfoa+Ck+6A6M10090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:79+4dyrYAcmGaiXQAY4ftSpU4hY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)