#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P46824 uniprotkb:P17210 intact:EBI-77490|ensemblmetazoa:FBpp0075683|ensemblmetazoa:FBpp0303945|uniprotkb:Q9VU05 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:klc_drome(display_long)|uniprotkb:Klc(gene name)|psi-mi:Klc(display_short)|uniprotkb:CG5433(orf name) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0096"(pull down) Wong et al. (2010) pubmed:20547877|doi:10.1073/pnas.1005854107|imex:IM-16440 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15861383|imex:IM-16440-1|dip:DIP-38037E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0010235(gene)|ensemblmetazoa:FBtr0075951(transcript)|ensemblmetazoa:FBtr0331555(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0046843"(dorsal appendage formation)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|reactome:R-DME-6811434|reactome:R-DME-983189|refseq:NP_524049.1|flybase:FBgn0010235|refseq:NP_001261780.1|dip:DIP-19091N refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:ggplfkjiCros+D00Q3kiqwGcRrE7227 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rigid:ZRqYwwKMBDviCIzWRPse9iaNTNY false sufficient binding region:1-148 binding-associated region:790-975|maltose binding protein tag:n-n - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P46824 uniprotkb:P17210 intact:EBI-77490|ensemblmetazoa:FBpp0075683|ensemblmetazoa:FBpp0303945|uniprotkb:Q9VU05 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:klc_drome(display_long)|uniprotkb:Klc(gene name)|psi-mi:Klc(display_short)|uniprotkb:CG5433(orf name) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0028"(cosedimentation in solution) Wong et al. (2010) pubmed:20547877|doi:10.1073/pnas.1005854107|imex:IM-16440 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15861406|imex:IM-16440-2|dip:DIP-38037E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0010235(gene)|ensemblmetazoa:FBtr0075951(transcript)|ensemblmetazoa:FBtr0331555(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0046843"(dorsal appendage formation)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|reactome:R-DME-6811434|reactome:R-DME-983189|refseq:NP_524049.1|flybase:FBgn0010235|refseq:NP_001261780.1|dip:DIP-19091N refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:ggplfkjiCros+D00Q3kiqwGcRrE7227 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rigid:ZRqYwwKMBDviCIzWRPse9iaNTNY false sufficient binding region:1-179 binding-associated region:790-975 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q99689 uniprotkb:P17210 intact:EBI-396435|uniprotkb:O00679|uniprotkb:O00728|uniprotkb:Q6IBI7|ensembl:ENSP00000278919|ensembl:ENSP00000497070 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:fez1_human(display_long)|uniprotkb:FEZ1(gene name)|psi-mi:FEZ1(display_short)|uniprotkb:Zygin-1(gene name synonym)|uniprotkb:Zygin I(gene name synonym) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0096"(pull down) Wong et al. (2010) pubmed:20547877|doi:10.1073/pnas.1005854107|imex:IM-16440 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15861427|imex:IM-16440-3|dip:DIP-187669E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005094.1|refseq:NP_072043.1|refseq:XP_005271791.1|refseq:XP_005271792.1|ensembl:ENSG00000149557(gene)|ensembl:ENST00000278919(transcript)|ensembl:ENST00000648911(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0061881"(positive regulation of anterograde axonal transport of mitochondrion)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|interpro:IPR015642(Fasciculation and elongation protein zeta 1)|dip:DIP-32494N refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:RKDxw2P5XBHcRtf1VQxY1t3bHVU9606 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rigid:jxCJ68+tlaDewYLBI7fWLlVMI6k false - binding-associated region:790-975|maltose binding protein tag:n-n - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P17210 uniprotkb:P17210 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Wong et al. (2010) pubmed:20547877|doi:10.1073/pnas.1005854107|imex:IM-16440 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15861448|imex:IM-16440-4|dip:DIP-187670E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rigid:1aJ3PwY24BC+ZheTW3d4nD+cL7Q false binding-associated region:1-401|fluorescein-5-maleimide label:195-195 binding-associated region:790-975 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17210 uniprotkb:Q99689 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 intact:EBI-396435|uniprotkb:O00679|uniprotkb:O00728|uniprotkb:Q6IBI7|ensembl:ENSP00000278919|ensembl:ENSP00000497070 psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:fez1_human(display_long)|uniprotkb:FEZ1(gene name)|psi-mi:FEZ1(display_short)|uniprotkb:Zygin-1(gene name synonym)|uniprotkb:Zygin I(gene name synonym) psi-mi:"MI:0096"(pull down) Wong et al. (2010) pubmed:20547877|doi:10.1073/pnas.1005854107|imex:IM-16440 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15861471|imex:IM-16440-5|dip:DIP-187668E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N refseq:NP_005094.1|refseq:NP_072043.1|refseq:XP_005271791.1|refseq:XP_005271792.1|ensembl:ENSG00000149557(gene)|ensembl:ENST00000278919(transcript)|ensembl:ENST00000648911(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0061881"(positive regulation of anterograde axonal transport of mitochondrion)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|interpro:IPR015642(Fasciculation and elongation protein zeta 1)|dip:DIP-32494N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rogid:RKDxw2P5XBHcRtf1VQxY1t3bHVU9606 rigid:Pu3k1nMDqcudMYdud++b57M4jdc false binding-associated region:790-975|maltose binding protein tag:n-n - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P17210 uniprotkb:P46824 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 intact:EBI-77490|ensemblmetazoa:FBpp0075683|ensemblmetazoa:FBpp0303945|uniprotkb:Q9VU05 psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:klc_drome(display_long)|uniprotkb:Klc(gene name)|psi-mi:Klc(display_short)|uniprotkb:CG5433(orf name) psi-mi:"MI:0096"(pull down) Wong et al. (2010) pubmed:20547877|doi:10.1073/pnas.1005854107|imex:IM-16440 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15861471|imex:IM-16440-5|dip:DIP-187668E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N ensemblmetazoa:FBgn0010235(gene)|ensemblmetazoa:FBtr0075951(transcript)|ensemblmetazoa:FBtr0331555(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0046843"(dorsal appendage formation)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|reactome:R-DME-6811434|reactome:R-DME-983189|refseq:NP_524049.1|flybase:FBgn0010235|refseq:NP_001261780.1|dip:DIP-19091N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rogid:ggplfkjiCros+D00Q3kiqwGcRrE7227 rigid:Pu3k1nMDqcudMYdud++b57M4jdc false binding-associated region:790-975|maltose binding protein tag:n-n - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q99689 uniprotkb:P17210 intact:EBI-396435|uniprotkb:O00679|uniprotkb:O00728|uniprotkb:Q6IBI7|ensembl:ENSP00000278919|ensembl:ENSP00000497070 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:fez1_human(display_long)|uniprotkb:FEZ1(gene name)|psi-mi:FEZ1(display_short)|uniprotkb:Zygin-1(gene name synonym)|uniprotkb:Zygin I(gene name synonym) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0028"(cosedimentation in solution) Wong et al. (2010) pubmed:20547877|doi:10.1073/pnas.1005854107|imex:IM-16440 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15861493|imex:IM-16440-6|dip:DIP-187669E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005094.1|refseq:NP_072043.1|refseq:XP_005271791.1|refseq:XP_005271792.1|ensembl:ENSG00000149557(gene)|ensembl:ENST00000278919(transcript)|ensembl:ENST00000648911(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0061881"(positive regulation of anterograde axonal transport of mitochondrion)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|interpro:IPR015642(Fasciculation and elongation protein zeta 1)|dip:DIP-32494N refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:RKDxw2P5XBHcRtf1VQxY1t3bHVU9606 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rigid:jxCJ68+tlaDewYLBI7fWLlVMI6k false - binding-associated region:790-975 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining)