#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q02574	uniprotkb:P14291	intact:EBI-10658|uniprotkb:P87260|uniprotkb:Q05887|ensemblfungi:YLR288C|uniprotkb:D6VYT4	intact:EBI-14909|ensemblfungi:YLR263W|uniprotkb:D6VYR0	psi-mi:mec3_yeast(display_long)|uniprotkb:MEC3(gene name)|psi-mi:MEC3(display_short)|uniprotkb:PIP3(gene name synonym)|uniprotkb:YLR288C(locus name)|uniprotkb:L8003.15(orf name)|uniprotkb:PSO9(gene name synonym)	psi-mi:red1_yeast(display_long)|uniprotkb:RED1(gene name)|psi-mi:RED1(display_short)|uniprotkb:YLR263W(locus name)|uniprotkb:L8479.6(orf name)|uniprotkb:Reductional division protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857487|imex:IM-17450-1|dip:DIP-188587E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013391.1|sgd:S000004279|ensemblfungi:YLR288C(gene)|ensemblfungi:YLR288C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006348"|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044778"(meiotic DNA integrity checkpoint signaling)|interpro:IPR007150(Hus1-like protein)|reactome:R-SCE-176187|mint:Q02574|dip:DIP-1432N	ensemblfungi:YLR263W(gene)|ensemblfungi:YLR263W_mRNA(transcript)|go:"GO:0000800"(lateral element)|go:"GO:0005198"(structural molecule activity)|go:"GO:0007130"(synaptonemal complex assembly)|refseq:NP_013365.1|sgd:S000004253|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR012491(Rec10/Red1)|dip:DIP-2372N	psi-mi:"MI:0465"(dip)	crc64:4385CEFA9130FEA3	crc64:CA1A206F9A274C3F	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:LuYCya9O8z1Uw0xyfJnz3aowolg559292	rogid:m8WfQmeXYPIYlmg5jAGhNfTbfl4559292	rigid:hNr90tUZPK2I6KdL0YtiU5ezIt0	false	-	sufficient binding region:531-827|mutation disrupting interaction strength:540-540,537-537	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14291	uniprotkb:Q12306	intact:EBI-14909|ensemblfungi:YLR263W|uniprotkb:D6VYR0	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:red1_yeast(display_long)|uniprotkb:RED1(gene name)|psi-mi:RED1(display_short)|uniprotkb:YLR263W(locus name)|uniprotkb:L8479.6(orf name)|uniprotkb:Reductional division protein 1(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0096"(pull down)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857529|imex:IM-17450-3|dip:DIP-7506E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR263W(gene)|ensemblfungi:YLR263W_mRNA(transcript)|go:"GO:0000800"(lateral element)|go:"GO:0005198"(structural molecule activity)|go:"GO:0007130"(synaptonemal complex assembly)|refseq:NP_013365.1|sgd:S000004253|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR012491(Rec10/Red1)|dip:DIP-2372N	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	psi-mi:"MI:0465"(dip)	crc64:CA1A206F9A274C3F	crc64:A2790DE7F315E1A7	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:m8WfQmeXYPIYlmg5jAGhNfTbfl4559292	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rigid:/ZOI6ok5+pq5LXUUDF2r2EdoV60	false	mutation disrupting interaction strength:590-590,585-585,584-584,581-581,580-580,579-579,577-577,576-576,572-572,570-570,569-569|mutation disrupting interaction strength:577-577,576-576,572-572,570-570,569-569|dna binding domain tag:n-n|sufficient binding region:531-827	his tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P14291	uniprotkb:P31111	intact:EBI-14909|ensemblfungi:YLR263W|uniprotkb:D6VYR0	intact:EBI-29645|uniprotkb:D6VSR5|ensemblfungi:YDR285W	psi-mi:red1_yeast(display_long)|uniprotkb:RED1(gene name)|psi-mi:RED1(display_short)|uniprotkb:YLR263W(locus name)|uniprotkb:L8479.6(orf name)|uniprotkb:Reductional division protein 1(gene name synonym)	psi-mi:zip1_yeast(display_long)|uniprotkb:ZIP1(gene name)|psi-mi:ZIP1(display_short)|uniprotkb:D9819.9(orf name)|uniprotkb:YDR285W(locus name)	psi-mi:"MI:0018"(two hybrid)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857572|imex:IM-17450-4|dip:DIP-153135E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR263W(gene)|ensemblfungi:YLR263W_mRNA(transcript)|go:"GO:0000800"(lateral element)|go:"GO:0005198"(structural molecule activity)|go:"GO:0007130"(synaptonemal complex assembly)|refseq:NP_013365.1|sgd:S000004253|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR012491(Rec10/Red1)|dip:DIP-2372N	sgd:S000002693|refseq:NP_010571.1|dip:DIP-1240N|ensemblfungi:YDR285W(gene)|ensemblfungi:YDR285W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000802"(transverse filament)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:1990166"(protein localization to site of double-strand break)	psi-mi:"MI:0465"(dip)	crc64:CA1A206F9A274C3F	crc64:674F12625CD9DDFD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:m8WfQmeXYPIYlmg5jAGhNfTbfl4559292	rogid:oYjQ9rwi/0WtJptBbJyCYfl9+5c559292	rigid:/DDwm0EsYsrgSaLsKlYSmoqiLTo	false	sufficient binding region:531-827|mutation disrupting interaction strength:590-590,585-585,584-584,581-581,580-580,579-579,577-577,576-576,572-572,570-570,569-569	sufficient binding region:846-875	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14291	uniprotkb:Q12306	intact:EBI-14909|ensemblfungi:YLR263W|uniprotkb:D6VYR0	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:red1_yeast(display_long)|uniprotkb:RED1(gene name)|psi-mi:RED1(display_short)|uniprotkb:YLR263W(locus name)|uniprotkb:L8479.6(orf name)|uniprotkb:Reductional division protein 1(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0096"(pull down)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857606|imex:IM-17450-5|dip:DIP-7506E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR263W(gene)|ensemblfungi:YLR263W_mRNA(transcript)|go:"GO:0000800"(lateral element)|go:"GO:0005198"(structural molecule activity)|go:"GO:0007130"(synaptonemal complex assembly)|refseq:NP_013365.1|sgd:S000004253|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR012491(Rec10/Red1)|dip:DIP-2372N	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	psi-mi:"MI:0465"(dip)	crc64:CA1A206F9A274C3F	crc64:A2790DE7F315E1A7	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:m8WfQmeXYPIYlmg5jAGhNfTbfl4559292	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rigid:/ZOI6ok5+pq5LXUUDF2r2EdoV60	false	mutation disrupting interaction strength:590-590,585-585,584-584,581-581,580-580,579-579,577-577,576-576,572-572,570-570,569-569	his tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P14291	uniprotkb:Q12306	intact:EBI-14909|ensemblfungi:YLR263W|uniprotkb:D6VYR0	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:red1_yeast(display_long)|uniprotkb:RED1(gene name)|psi-mi:RED1(display_short)|uniprotkb:YLR263W(locus name)|uniprotkb:L8479.6(orf name)|uniprotkb:Reductional division protein 1(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0096"(pull down)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857510|imex:IM-17450-2|dip:DIP-7506E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR263W(gene)|ensemblfungi:YLR263W_mRNA(transcript)|go:"GO:0000800"(lateral element)|go:"GO:0005198"(structural molecule activity)|go:"GO:0007130"(synaptonemal complex assembly)|refseq:NP_013365.1|sgd:S000004253|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR012491(Rec10/Red1)|dip:DIP-2372N	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	psi-mi:"MI:0465"(dip)	crc64:CA1A206F9A274C3F	crc64:A2790DE7F315E1A7	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:m8WfQmeXYPIYlmg5jAGhNfTbfl4559292	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rigid:/ZOI6ok5+pq5LXUUDF2r2EdoV60	false	-	his tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08949	uniprotkb:P14291	intact:EBI-30769|uniprotkb:D6W3H4|ensemblfungi:YPL194W	intact:EBI-14909|ensemblfungi:YLR263W|uniprotkb:D6VYR0	psi-mi:ddc1_yeast(display_long)|uniprotkb:DDC1(gene name)|psi-mi:DDC1(display_short)|uniprotkb:YPL194W(locus name)	psi-mi:red1_yeast(display_long)|uniprotkb:RED1(gene name)|psi-mi:RED1(display_short)|uniprotkb:YLR263W(locus name)|uniprotkb:L8479.6(orf name)|uniprotkb:Reductional division protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857638|imex:IM-17450-6|dip:DIP-188588E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015130.1|sgd:S000006115|dip:DIP-2323N|reactome:R-SCE-176187|ensemblfungi:YPL194W(gene)|ensemblfungi:YPL194W_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000725"(recombinational repair)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR007268(Rad9)|interpro:IPR026217	ensemblfungi:YLR263W(gene)|ensemblfungi:YLR263W_mRNA(transcript)|go:"GO:0000800"(lateral element)|go:"GO:0005198"(structural molecule activity)|go:"GO:0007130"(synaptonemal complex assembly)|refseq:NP_013365.1|sgd:S000004253|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR012491(Rec10/Red1)|dip:DIP-2372N	psi-mi:"MI:0465"(dip)	crc64:F9933697C61021D3	crc64:CA1A206F9A274C3F	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:lkKb3OuvQqiwmNiAlWp3D1EqNB8559292	rogid:m8WfQmeXYPIYlmg5jAGhNfTbfl4559292	rigid:sDMkyV/oWKnTX0PkrYiI4HSIpbY	false	-	sufficient binding region:729-827|mutation disrupting interaction strength:743-743	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40537	uniprotkb:P14291	intact:EBI-20059|uniprotkb:D6VVQ0|ensemblfungi:YIL031W	intact:EBI-14909|ensemblfungi:YLR263W|uniprotkb:D6VYR0	psi-mi:ulp2_yeast(display_long)|uniprotkb:ULP2(gene name)|psi-mi:ULP2(display_short)|uniprotkb:SMT4(gene name synonym)|uniprotkb:YIL031W(locus name)	psi-mi:red1_yeast(display_long)|uniprotkb:RED1(gene name)|psi-mi:RED1(display_short)|uniprotkb:YLR263W(locus name)|uniprotkb:L8479.6(orf name)|uniprotkb:Reductional division protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857660|imex:IM-17450-7|dip:DIP-188590E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012233.1|sgd:S000001293|go:"GO:0003711"(transcription elongation regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|ensemblfungi:YIL031W(gene)|go:"GO:0030261"(chromosome condensation)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:5LNB|rcsb pdb:5V1A|ensemblfungi:YIL031W_mRNA(transcript)|dip:DIP-5489N|reactome:R-SCE-3065679|reactome:R-SCE-6791226	ensemblfungi:YLR263W(gene)|ensemblfungi:YLR263W_mRNA(transcript)|go:"GO:0000800"(lateral element)|go:"GO:0005198"(structural molecule activity)|go:"GO:0007130"(synaptonemal complex assembly)|refseq:NP_013365.1|sgd:S000004253|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR012491(Rec10/Red1)|dip:DIP-2372N	psi-mi:"MI:0465"(dip)	crc64:782789B3B1DC37F6	crc64:CA1A206F9A274C3F	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:3rvZUCsCOB+g1WvNh97s1w32t9I559292	rogid:m8WfQmeXYPIYlmg5jAGhNfTbfl4559292	rigid:LUrYz1i8pzOlLWISkYL3O1sRCHw	false	mutation:624-624	sufficient binding region:531-827|mutation disrupting interaction strength:590-590,585-585,584-584,581-581,580-580,579-579,577-577,576-576,572-572,570-570,569-569	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14291	uniprotkb:P14291	intact:EBI-14909|ensemblfungi:YLR263W|uniprotkb:D6VYR0	intact:EBI-14909|ensemblfungi:YLR263W|uniprotkb:D6VYR0	psi-mi:red1_yeast(display_long)|uniprotkb:RED1(gene name)|psi-mi:RED1(display_short)|uniprotkb:YLR263W(locus name)|uniprotkb:L8479.6(orf name)|uniprotkb:Reductional division protein 1(gene name synonym)	psi-mi:red1_yeast(display_long)|uniprotkb:RED1(gene name)|psi-mi:RED1(display_short)|uniprotkb:YLR263W(locus name)|uniprotkb:L8479.6(orf name)|uniprotkb:Reductional division protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857695|imex:IM-17450-8|dip:DIP-3199E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR263W(gene)|ensemblfungi:YLR263W_mRNA(transcript)|go:"GO:0000800"(lateral element)|go:"GO:0005198"(structural molecule activity)|go:"GO:0007130"(synaptonemal complex assembly)|refseq:NP_013365.1|sgd:S000004253|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR012491(Rec10/Red1)|dip:DIP-2372N	ensemblfungi:YLR263W(gene)|ensemblfungi:YLR263W_mRNA(transcript)|go:"GO:0000800"(lateral element)|go:"GO:0005198"(structural molecule activity)|go:"GO:0007130"(synaptonemal complex assembly)|refseq:NP_013365.1|sgd:S000004253|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR012491(Rec10/Red1)|dip:DIP-2372N	psi-mi:"MI:0465"(dip)	crc64:CA1A206F9A274C3F	crc64:CA1A206F9A274C3F	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:m8WfQmeXYPIYlmg5jAGhNfTbfl4559292	rogid:m8WfQmeXYPIYlmg5jAGhNfTbfl4559292	rigid:+9d0cttcHACSYClzwxl5scEJz1M	false	sufficient binding region:703-827	sufficient binding region:751-827	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04637	uniprotkb:P63165	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5	intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name)	psi-mi:"MI:0096"(pull down)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857716|imex:IM-17450-9|dip:DIP-57081E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N	refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606	rigid:qNv2VfkxXgSkvI8x1fYzGK12UaM	false	-	his tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P14291	uniprotkb:Q12306	intact:EBI-14909|ensemblfungi:YLR263W|uniprotkb:D6VYR0	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:red1_yeast(display_long)|uniprotkb:RED1(gene name)|psi-mi:RED1(display_short)|uniprotkb:YLR263W(locus name)|uniprotkb:L8479.6(orf name)|uniprotkb:Reductional division protein 1(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0018"(two hybrid)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857735|imex:IM-17450-10|dip:DIP-7506E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR263W(gene)|ensemblfungi:YLR263W_mRNA(transcript)|go:"GO:0000800"(lateral element)|go:"GO:0005198"(structural molecule activity)|go:"GO:0007130"(synaptonemal complex assembly)|refseq:NP_013365.1|sgd:S000004253|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR012491(Rec10/Red1)|dip:DIP-2372N	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	psi-mi:"MI:0465"(dip)	crc64:CA1A206F9A274C3F	crc64:A2790DE7F315E1A7	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:m8WfQmeXYPIYlmg5jAGhNfTbfl4559292	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rigid:/ZOI6ok5+pq5LXUUDF2r2EdoV60	false	sufficient binding region:531-827	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12306	uniprotkb:P31111	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	intact:EBI-29645|uniprotkb:D6VSR5|ensemblfungi:YDR285W	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:zip1_yeast(display_long)|uniprotkb:ZIP1(gene name)|psi-mi:ZIP1(display_short)|uniprotkb:D9819.9(orf name)|uniprotkb:YDR285W(locus name)	psi-mi:"MI:0018"(two hybrid)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857754|imex:IM-17450-11|dip:DIP-153136E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	sgd:S000002693|refseq:NP_010571.1|dip:DIP-1240N|ensemblfungi:YDR285W(gene)|ensemblfungi:YDR285W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000802"(transverse filament)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:1990166"(protein localization to site of double-strand break)	psi-mi:"MI:0465"(dip)	crc64:A2790DE7F315E1A7	crc64:674F12625CD9DDFD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rogid:oYjQ9rwi/0WtJptBbJyCYfl9+5c559292	rigid:muMMvMOQPX6/gPdxD8Iu/yFc06w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50623	uniprotkb:P14291	intact:EBI-19760|uniprotkb:D6VRT3|ensemblfungi:YDL064W	intact:EBI-14909|ensemblfungi:YLR263W|uniprotkb:D6VYR0	psi-mi:ubc9_yeast(display_long)|uniprotkb:UBC9(gene name)|psi-mi:UBC9(display_short)|uniprotkb:Ubiquitin-conjugating enzyme E2-18 kDa(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:YDL064W(locus name)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:red1_yeast(display_long)|uniprotkb:RED1(gene name)|psi-mi:RED1(display_short)|uniprotkb:YLR263W(locus name)|uniprotkb:L8479.6(orf name)|uniprotkb:Reductional division protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857771|imex:IM-17450-12|dip:DIP-188591E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010219.1|sgd:S000002222|reactome:R-SCE-3065678|reactome:R-SCE-3108214|reactome:R-SCE-3232118|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-4085377|ensemblfungi:YDL064W(gene)|ensemblfungi:YDL064W_mRNA(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR027230|rcsb pdb:2EKE|rcsb pdb:2GJD|rcsb pdb:3ONG|rcsb pdb:5JNE|rcsb pdb:6Q83|dip:DIP-1531N|reactome:R-SCE-4551638|reactome:R-SCE-3899300|reactome:R-SCE-3108232|reactome:R-SCE-9615933	ensemblfungi:YLR263W(gene)|ensemblfungi:YLR263W_mRNA(transcript)|go:"GO:0000800"(lateral element)|go:"GO:0005198"(structural molecule activity)|go:"GO:0007130"(synaptonemal complex assembly)|refseq:NP_013365.1|sgd:S000004253|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR012491(Rec10/Red1)|dip:DIP-2372N	psi-mi:"MI:0465"(dip)	crc64:D74EE9845BB677B4	crc64:CA1A206F9A274C3F	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:mTdEVn/bucUQ/kuDsh7UseB9S70559292	rogid:m8WfQmeXYPIYlmg5jAGhNfTbfl4559292	rigid:8iIwwRkRk20G2PhRdjblQin/JCo	false	-	sufficient binding region:531-827	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61956	uniprotkb:Q8IZU3	intact:EBI-473220|uniprotkb:P55855|uniprotkb:Q6IPZ6|ensembl:ENSP00000405965|uniprotkb:Q32Q42|uniprotkb:Q96HK1|intact:EBI-2512339|uniprotkb:B2R4I2	intact:EBI-7574149|intact:MINT-8303450|ensembl:ENSP00000266743|ensembl:ENSP00000376655|ensembl:ENSP00000376658	psi-mi:sumo2_human(display_long)|uniprotkb:SMT3 homolog 2(gene name synonym)|uniprotkb:Sentrin-2(gene name synonym)|uniprotkb:HSMT3(gene name synonym)|uniprotkb:SUMO-3(gene name synonym)|uniprotkb:SUMO2(gene name)|psi-mi:SUMO2(display_short)|uniprotkb:SMT3H2(gene name synonym)|uniprotkb:SMT3B(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3B(gene name synonym)	psi-mi:sycp3_human(display_long)|uniprotkb:SYCP3(gene name)|psi-mi:SYCP3(display_short)|uniprotkb:SCP3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857790|imex:IM-17450-13|dip:DIP-188592E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1Z5Q|rcsb pdb:2AWT|rcsb pdb:2CKH|rcsb pdb:2D07|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P61956|rcsb pdb:1WM2|rcsb pdb:1WM3|rcsb pdb:1WZ0|rcsb pdb:2IO0|ensembl:ENSG00000188612(gene)|ensembl:ENST00000420826(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001005849.1|refseq:NP_008868.3|rcsb pdb:2IO3|rcsb pdb:6JXW|rcsb pdb:6JXX|reactome:R-HSA-196791|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5693607|reactome:R-HSA-5696395|rcsb pdb:5GHC|rcsb pdb:5D2M|rcsb pdb:5ELU|rcsb pdb:5EQL|rcsb pdb:5GHB|rcsb pdb:2IYD|rcsb pdb:2N1W|rcsb pdb:2N9E|rcsb pdb:2RPQ|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3ZO5|rcsb pdb:4BKG|rcsb pdb:4NPN|dip:DIP-29253N	refseq:NP_001171420.1|refseq:NP_001171419.1|refseq:NP_710161.1|ensembl:ENSG00000139351(gene)|ensembl:ENST00000266743(transcript)|ensembl:ENST00000392924(transcript)|ensembl:ENST00000392927(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007141"(male meiosis I)|go:"GO:0007286"(spermatid development)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|rcsb pdb:4CPC|reactome:R-HSA-1221632|dip:DIP-59536N	psi-mi:"MI:0465"(dip)	-	comment:mint|comment:homomint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:WgudlZhwtQbQInv29BniecTYGY89606	rogid:NjKYmSQYvDyGGOjX2r6MP6ukluw9606	rigid:NWG6v19zqtWkuflTIwQTbJgoSZc	false	his tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61956	uniprotkb:P04637	intact:EBI-473220|uniprotkb:P55855|uniprotkb:Q6IPZ6|ensembl:ENSP00000405965|uniprotkb:Q32Q42|uniprotkb:Q96HK1|intact:EBI-2512339|uniprotkb:B2R4I2	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5	psi-mi:sumo2_human(display_long)|uniprotkb:SMT3 homolog 2(gene name synonym)|uniprotkb:Sentrin-2(gene name synonym)|uniprotkb:HSMT3(gene name synonym)|uniprotkb:SUMO-3(gene name synonym)|uniprotkb:SUMO2(gene name)|psi-mi:SUMO2(display_short)|uniprotkb:SMT3H2(gene name synonym)|uniprotkb:SMT3B(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3B(gene name synonym)	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857790|imex:IM-17450-13|dip:DIP-188592E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1Z5Q|rcsb pdb:2AWT|rcsb pdb:2CKH|rcsb pdb:2D07|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P61956|rcsb pdb:1WM2|rcsb pdb:1WM3|rcsb pdb:1WZ0|rcsb pdb:2IO0|ensembl:ENSG00000188612(gene)|ensembl:ENST00000420826(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001005849.1|refseq:NP_008868.3|rcsb pdb:2IO3|rcsb pdb:6JXW|rcsb pdb:6JXX|reactome:R-HSA-196791|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5693607|reactome:R-HSA-5696395|rcsb pdb:5GHC|rcsb pdb:5D2M|rcsb pdb:5ELU|rcsb pdb:5EQL|rcsb pdb:5GHB|rcsb pdb:2IYD|rcsb pdb:2N1W|rcsb pdb:2N9E|rcsb pdb:2RPQ|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3ZO5|rcsb pdb:4BKG|rcsb pdb:4NPN|dip:DIP-29253N	refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:WgudlZhwtQbQInv29BniecTYGY89606	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	rigid:NWG6v19zqtWkuflTIwQTbJgoSZc	false	his tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P31111	uniprotkb:P31111	intact:EBI-29645|uniprotkb:D6VSR5|ensemblfungi:YDR285W	intact:EBI-29645|uniprotkb:D6VSR5|ensemblfungi:YDR285W	psi-mi:zip1_yeast(display_long)|uniprotkb:ZIP1(gene name)|psi-mi:ZIP1(display_short)|uniprotkb:D9819.9(orf name)|uniprotkb:YDR285W(locus name)	psi-mi:zip1_yeast(display_long)|uniprotkb:ZIP1(gene name)|psi-mi:ZIP1(display_short)|uniprotkb:D9819.9(orf name)|uniprotkb:YDR285W(locus name)	psi-mi:"MI:0018"(two hybrid)	Eichinger et al. (2010)	pubmed:20534433|doi:10.1073/pnas.1004248107|imex:IM-17450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15857812|imex:IM-17450-14|dip:DIP-188589E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002693|refseq:NP_010571.1|dip:DIP-1240N|ensemblfungi:YDR285W(gene)|ensemblfungi:YDR285W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000802"(transverse filament)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:1990166"(protein localization to site of double-strand break)	sgd:S000002693|refseq:NP_010571.1|dip:DIP-1240N|ensemblfungi:YDR285W(gene)|ensemblfungi:YDR285W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000802"(transverse filament)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:1990166"(protein localization to site of double-strand break)	psi-mi:"MI:0465"(dip)	crc64:674F12625CD9DDFD	crc64:674F12625CD9DDFD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:oYjQ9rwi/0WtJptBbJyCYfl9+5c559292	rogid:oYjQ9rwi/0WtJptBbJyCYfl9+5c559292	rigid:TlR40rCIelC0201uE/Ej7HE+ZxM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)