#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q07436	uniprotkb:P10040	intact:EBI-192660|uniprotkb:Q9VPQ0|ensemblmetazoa:FBpp0077719|ensemblmetazoa:FBpp0302878	intact:EBI-672928|uniprotkb:Q0KI19|uniprotkb:Q8MSX5|uniprotkb:Q9VC97|ensemblmetazoa:FBpp0083987	psi-mi:expa_drome(display_long)|uniprotkb:ex(gene name)|psi-mi:ex(display_short)|uniprotkb:CG4114(orf name)	psi-mi:crb_drome(display_long)|uniprotkb:95F(gene name synonym)|uniprotkb:crb(gene name)|psi-mi:crb(display_short)|uniprotkb:CG6383(orf name)	psi-mi:"MI:0096"(pull down)	Ling et al. (2010)	pubmed:20498073|doi:10.1073/pnas.1004279107|imex:IM-16421	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15856166|imex:IM-16421-1|dip:DIP-187637E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476840.2|flybase:FBgn0004583|refseq:NP_001259823.1|dip:DIP-59337N|ensemblmetazoa:FBgn0004583(gene)|ensemblmetazoa:FBtr0078059(transcript)|ensemblmetazoa:FBtr0329832(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0120219"(subapical part of cell)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041781|reactome:R-DME-451806	refseq:NP_001036751.1|refseq:NP_524480.2|flybase:FBgn0259685|dip:DIP-40915N|ensemblmetazoa:FBgn0259685(gene)|ensemblmetazoa:FBtr0084603(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003383"(apical constriction)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016332"(establishment or maintenance of polarity of embryonic epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0034332"(adherens junction organization)|go:"GO:0035002"(liquid clearance, open tracheal system)|go:"GO:0035003"(subapical complex)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035090"(maintenance of apical/basal cell polarity)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042052"(rhabdomere development)|go:"GO:0045176"(apical protein localization)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046665"(amnioserosa maintenance)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0060438"(trachea development)|go:"GO:0061024"(membrane organization)|go:"GO:0061336"(cell morphogenesis involved in Malpighian tubule morphogenesis)|go:"GO:0061541"(rhabdomere morphogenesis)|go:"GO:0098813"(nuclear chromosome segregation)|go:"GO:0106036"(assembly of apicomedial cortex actomyosin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4WSI|rcsb pdb:4YL8	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:jCsq6JzSOCfaz06zd5R8hdkiWVg7227	rogid:eFe13WHwi5bdLUm1xQxhj22j9JU7227	rigid:hAFmrqxCrsonkudEu6pI7wFBCds	false	v5 tag:n-n	binding-associated region:2110-2146|mutation disrupting interaction:2125-2125,2121-2121,2119-2119|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q07436	uniprotkb:P10040	intact:EBI-192660|uniprotkb:Q9VPQ0|ensemblmetazoa:FBpp0077719|ensemblmetazoa:FBpp0302878	intact:EBI-672928|uniprotkb:Q0KI19|uniprotkb:Q8MSX5|uniprotkb:Q9VC97|ensemblmetazoa:FBpp0083987	psi-mi:expa_drome(display_long)|uniprotkb:ex(gene name)|psi-mi:ex(display_short)|uniprotkb:CG4114(orf name)	psi-mi:crb_drome(display_long)|uniprotkb:95F(gene name synonym)|uniprotkb:crb(gene name)|psi-mi:crb(display_short)|uniprotkb:CG6383(orf name)	psi-mi:"MI:0096"(pull down)	Ling et al. (2010)	pubmed:20498073|doi:10.1073/pnas.1004279107|imex:IM-16421	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15856196|imex:IM-16421-2|dip:DIP-187637E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476840.2|flybase:FBgn0004583|refseq:NP_001259823.1|dip:DIP-59337N|ensemblmetazoa:FBgn0004583(gene)|ensemblmetazoa:FBtr0078059(transcript)|ensemblmetazoa:FBtr0329832(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0120219"(subapical part of cell)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041781|reactome:R-DME-451806	refseq:NP_001036751.1|refseq:NP_524480.2|flybase:FBgn0259685|dip:DIP-40915N|ensemblmetazoa:FBgn0259685(gene)|ensemblmetazoa:FBtr0084603(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003383"(apical constriction)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016332"(establishment or maintenance of polarity of embryonic epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0034332"(adherens junction organization)|go:"GO:0035002"(liquid clearance, open tracheal system)|go:"GO:0035003"(subapical complex)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035090"(maintenance of apical/basal cell polarity)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042052"(rhabdomere development)|go:"GO:0045176"(apical protein localization)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046665"(amnioserosa maintenance)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0060438"(trachea development)|go:"GO:0061024"(membrane organization)|go:"GO:0061336"(cell morphogenesis involved in Malpighian tubule morphogenesis)|go:"GO:0061541"(rhabdomere morphogenesis)|go:"GO:0098813"(nuclear chromosome segregation)|go:"GO:0106036"(assembly of apicomedial cortex actomyosin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4WSI|rcsb pdb:4YL8	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:jCsq6JzSOCfaz06zd5R8hdkiWVg7227	rogid:eFe13WHwi5bdLUm1xQxhj22j9JU7227	rigid:hAFmrqxCrsonkudEu6pI7wFBCds	false	myc tag:n-n	binding-associated region:2110-2146|mutation disrupting interaction:2125-2125,2121-2121,2119-2119|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)