#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P09883 uniprotkb:P04482 intact:EBI-1029888 intact:EBI-15855054 psi-mi:cea9_ecolx(display_long)|uniprotkb:col(gene name)|psi-mi:col(display_short)|uniprotkb:cei(gene name synonym) psi-mi:imm2_ecolx(display_long)|uniprotkb:imm(gene name)|psi-mi:imm(display_short)|uniprotkb:ceiB(gene name synonym)|uniprotkb:ImmE2(gene name synonym)|uniprotkb:Microcin-E2 immunity protein(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Meenan et al. (2010) pubmed:20479265|doi:10.1073/pnas.0910756107|imex:IM-16417 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15855073|imex:IM-16417-1|dip:DIP-187633E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_002533537.1|interpro:IPR016128(Pyosin/cloacin, translocation)|interpro:IPR024566|interpro:IPR024575|interpro:IPR036302|interpro:IPR037146|rcsb pdb:1BXI|rcsb pdb:1EMV|rcsb pdb:1FR2|rcsb pdb:1FSJ|rcsb pdb:1V13|rcsb pdb:1V14|rcsb pdb:1V15|rcsb pdb:2GYK|rcsb pdb:2GZE|rcsb pdb:2GZF|rcsb pdb:2GZG|rcsb pdb:2GZI|rcsb pdb:2GZJ|rcsb pdb:2IVZ|rcsb pdb:2K5X|rcsb pdb:2VLN|rcsb pdb:2VLO|rcsb pdb:2VLP|rcsb pdb:2VLQ|rcsb pdb:2WPT|rcsb pdb:3O0E|interpro:IPR003615(HNH nuclease)|rcsb pdb:4JML|rcsb pdb:5EW5|go:"GO:0004519"(endonuclease activity)|go:"GO:0005727"(extrachromosomal circular DNA)|go:"GO:0019835"(cytolysis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046872"(metal ion binding)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|refseq:WP_012644886.1|dip:DIP-16992N go:"GO:0015643"(toxic substance binding)|go:"GO:0030153"(bacteriocin immunity)|interpro:IPR000290(Colicin immunity protein/pyocin immunity protein)|interpro:IPR035900|rcsb pdb:2NO8|rcsb pdb:2WPT|rcsb pdb:3U43|refseq:WP_000420693.1|refseq:YP_001966153.1|refseq:YP_002221665.1|dip:DIP-59336N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:dNw0MxBfriwiX03AkbH/r1DorOA562 rogid:GLZelyUI/TVTDBdM3gYU3e4XqjI562 rigid:Z1ZkwKd+NoZc1k/QYd9xTpliKLk false binding-associated region:450-582 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09883 uniprotkb:P04482 intact:EBI-1029888 intact:EBI-15855054 psi-mi:cea9_ecolx(display_long)|uniprotkb:col(gene name)|psi-mi:col(display_short)|uniprotkb:cei(gene name synonym) psi-mi:imm2_ecolx(display_long)|uniprotkb:imm(gene name)|psi-mi:imm(display_short)|uniprotkb:ceiB(gene name synonym)|uniprotkb:ImmE2(gene name synonym)|uniprotkb:Microcin-E2 immunity protein(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Meenan et al. (2010) pubmed:20479265|doi:10.1073/pnas.0910756107|imex:IM-16417 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15855092|imex:IM-16417-2|dip:DIP-187633E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_002533537.1|interpro:IPR016128(Pyosin/cloacin, translocation)|interpro:IPR024566|interpro:IPR024575|interpro:IPR036302|interpro:IPR037146|rcsb pdb:1BXI|rcsb pdb:1EMV|rcsb pdb:1FR2|rcsb pdb:1FSJ|rcsb pdb:1V13|rcsb pdb:1V14|rcsb pdb:1V15|rcsb pdb:2GYK|rcsb pdb:2GZE|rcsb pdb:2GZF|rcsb pdb:2GZG|rcsb pdb:2GZI|rcsb pdb:2GZJ|rcsb pdb:2IVZ|rcsb pdb:2K5X|rcsb pdb:2VLN|rcsb pdb:2VLO|rcsb pdb:2VLP|rcsb pdb:2VLQ|rcsb pdb:2WPT|rcsb pdb:3O0E|interpro:IPR003615(HNH nuclease)|rcsb pdb:4JML|rcsb pdb:5EW5|go:"GO:0004519"(endonuclease activity)|go:"GO:0005727"(extrachromosomal circular DNA)|go:"GO:0019835"(cytolysis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046872"(metal ion binding)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|refseq:WP_012644886.1|dip:DIP-16992N go:"GO:0015643"(toxic substance binding)|go:"GO:0030153"(bacteriocin immunity)|interpro:IPR000290(Colicin immunity protein/pyocin immunity protein)|interpro:IPR035900|rcsb pdb:2NO8|rcsb pdb:2WPT|rcsb pdb:3U43|refseq:WP_000420693.1|refseq:YP_001966153.1|refseq:YP_002221665.1|dip:DIP-59336N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:dNw0MxBfriwiX03AkbH/r1DorOA562 rogid:GLZelyUI/TVTDBdM3gYU3e4XqjI562 rigid:Z1ZkwKd+NoZc1k/QYd9xTpliKLk false binding-associated region:450-582|mutation:543-543 mutation:31-31 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09883 uniprotkb:P04482 intact:EBI-1029888 intact:EBI-15855054 psi-mi:cea9_ecolx(display_long)|uniprotkb:col(gene name)|psi-mi:col(display_short)|uniprotkb:cei(gene name synonym) psi-mi:imm2_ecolx(display_long)|uniprotkb:imm(gene name)|psi-mi:imm(display_short)|uniprotkb:ceiB(gene name synonym)|uniprotkb:ImmE2(gene name synonym)|uniprotkb:Microcin-E2 immunity protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Meenan et al. (2010) pubmed:20479265|doi:10.1073/pnas.0910756107|imex:IM-16417 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15855117|imex:IM-16417-3|dip:DIP-187633E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_002533537.1|interpro:IPR016128(Pyosin/cloacin, translocation)|interpro:IPR024566|interpro:IPR024575|interpro:IPR036302|interpro:IPR037146|rcsb pdb:1BXI|rcsb pdb:1EMV|rcsb pdb:1FR2|rcsb pdb:1FSJ|rcsb pdb:1V13|rcsb pdb:1V14|rcsb pdb:1V15|rcsb pdb:2GYK|rcsb pdb:2GZE|rcsb pdb:2GZF|rcsb pdb:2GZG|rcsb pdb:2GZI|rcsb pdb:2GZJ|rcsb pdb:2IVZ|rcsb pdb:2K5X|rcsb pdb:2VLN|rcsb pdb:2VLO|rcsb pdb:2VLP|rcsb pdb:2VLQ|rcsb pdb:2WPT|rcsb pdb:3O0E|interpro:IPR003615(HNH nuclease)|rcsb pdb:4JML|rcsb pdb:5EW5|go:"GO:0004519"(endonuclease activity)|go:"GO:0005727"(extrachromosomal circular DNA)|go:"GO:0019835"(cytolysis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046872"(metal ion binding)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|refseq:WP_012644886.1|dip:DIP-16992N go:"GO:0015643"(toxic substance binding)|go:"GO:0030153"(bacteriocin immunity)|interpro:IPR000290(Colicin immunity protein/pyocin immunity protein)|interpro:IPR035900|rcsb pdb:2NO8|rcsb pdb:2WPT|rcsb pdb:3U43|refseq:WP_000420693.1|refseq:YP_001966153.1|refseq:YP_002221665.1|dip:DIP-59336N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:dNw0MxBfriwiX03AkbH/r1DorOA562 rogid:GLZelyUI/TVTDBdM3gYU3e4XqjI562 rigid:Z1ZkwKd+NoZc1k/QYd9xTpliKLk false binding-associated region:450-582 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09883 uniprotkb:P04482 intact:EBI-1029888 intact:EBI-15855054 psi-mi:cea9_ecolx(display_long)|uniprotkb:col(gene name)|psi-mi:col(display_short)|uniprotkb:cei(gene name synonym) psi-mi:imm2_ecolx(display_long)|uniprotkb:imm(gene name)|psi-mi:imm(display_short)|uniprotkb:ceiB(gene name synonym)|uniprotkb:ImmE2(gene name synonym)|uniprotkb:Microcin-E2 immunity protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Meenan et al. (2010) pubmed:20479265|doi:10.1073/pnas.0910756107|imex:IM-16417 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15855137|imex:IM-16417-4|dip:DIP-187633E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_002533537.1|interpro:IPR016128(Pyosin/cloacin, translocation)|interpro:IPR024566|interpro:IPR024575|interpro:IPR036302|interpro:IPR037146|rcsb pdb:1BXI|rcsb pdb:1EMV|rcsb pdb:1FR2|rcsb pdb:1FSJ|rcsb pdb:1V13|rcsb pdb:1V14|rcsb pdb:1V15|rcsb pdb:2GYK|rcsb pdb:2GZE|rcsb pdb:2GZF|rcsb pdb:2GZG|rcsb pdb:2GZI|rcsb pdb:2GZJ|rcsb pdb:2IVZ|rcsb pdb:2K5X|rcsb pdb:2VLN|rcsb pdb:2VLO|rcsb pdb:2VLP|rcsb pdb:2VLQ|rcsb pdb:2WPT|rcsb pdb:3O0E|interpro:IPR003615(HNH nuclease)|rcsb pdb:4JML|rcsb pdb:5EW5|go:"GO:0004519"(endonuclease activity)|go:"GO:0005727"(extrachromosomal circular DNA)|go:"GO:0019835"(cytolysis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046872"(metal ion binding)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|refseq:WP_012644886.1|dip:DIP-16992N go:"GO:0015643"(toxic substance binding)|go:"GO:0030153"(bacteriocin immunity)|interpro:IPR000290(Colicin immunity protein/pyocin immunity protein)|interpro:IPR035900|rcsb pdb:2NO8|rcsb pdb:2WPT|rcsb pdb:3U43|refseq:WP_000420693.1|refseq:YP_001966153.1|refseq:YP_002221665.1|dip:DIP-59336N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:dNw0MxBfriwiX03AkbH/r1DorOA562 rogid:GLZelyUI/TVTDBdM3gYU3e4XqjI562 rigid:Z1ZkwKd+NoZc1k/QYd9xTpliKLk false binding-associated region:450-582 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)