#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q61543 uniprotkb:Q00690 intact:EBI-8329826|uniprotkb:Q9QZ40|intact:MINT-1836383|ensembl:ENSMUSP00000131355 intact:EBI-15852222 psi-mi:gslg1_mouse(display_long)|uniprotkb:Glg1(gene name)|psi-mi:Glg1(display_short)|uniprotkb:Esl1(gene name synonym)|uniprotkb:Mg160(gene name synonym)|uniprotkb:Selel(gene name synonym)|uniprotkb:Golgi sialoglycoprotein MG-160(gene name synonym)|uniprotkb:E-selectin ligand 1(gene name synonym) psi-mi:lyam2_mouse(display_long)|uniprotkb:Sele(gene name)|psi-mi:Sele(display_short)|uniprotkb:Elam-1(gene name synonym)|uniprotkb:CD62 antigen-like family member E(gene name synonym)|uniprotkb:Endothelial leukocyte adhesion molecule 1(gene name synonym)|uniprotkb:Leukocyte-endothelial cell adhesion molecule 2(gene name synonym) psi-mi:"MI:0096"(pull down) Yago et al. (2010) pubmed:20439727|doi:10.1073/pnas.1003110107|imex:IM-16407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15852264|imex:IM-16407-1|dip:DIP-187616E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033175.1|dip:DIP-59329N|ensembl:ENSMUSG00000003316(gene)|ensembl:ENSMUST00000169020(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060349"(bone morphogenesis)|interpro:IPR001893(Cysteine rich repeat)|interpro:IPR017873|interpro:IPR039728|mint:Q61543|reactome:R-MMU-202733 go:"GO:0070492"(oligosaccharide binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR033991|interpro:IPR035976|interpro:IPR001304(C-type lectin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002396("Selectin (CD62E/L/P antigen)")|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006954"(inflammatory response)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0033691"(sialic acid binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050901"(leukocyte tethering or rolling)|reactome:R-MMU-202733|refseq:NP_035475.1|refseq:XP_006496778.1|dip:DIP-59328N psi-mi:"MI:0465"(dip) comment:mint|function:"Binds fibroblast growth factor (By similarity). Binds E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils)" - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:/Oi00BW7+LzOnpkTUY2ARkSA5rQ10090 rogid:iPA+EqV56QAIMKxfD3yG28iBqpk10090 rigid:zhPkcrbxDlUUofeBfOMjmE/+XeA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q62170 uniprotkb:Q00690 intact:EBI-15852281 intact:EBI-15852222 psi-mi:selpl_mouse(display_long)|uniprotkb:Selplg(gene name)|psi-mi:Selplg(display_short)|uniprotkb:Selp1(gene name synonym)|uniprotkb:Selpl(gene name synonym)|uniprotkb:Selectin P ligand(gene name synonym) psi-mi:lyam2_mouse(display_long)|uniprotkb:Sele(gene name)|psi-mi:Sele(display_short)|uniprotkb:Elam-1(gene name synonym)|uniprotkb:CD62 antigen-like family member E(gene name synonym)|uniprotkb:Endothelial leukocyte adhesion molecule 1(gene name synonym)|uniprotkb:Leukocyte-endothelial cell adhesion molecule 2(gene name synonym) psi-mi:"MI:0096"(pull down) Yago et al. (2010) pubmed:20439727|doi:10.1073/pnas.1003110107|imex:IM-16407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15852298|imex:IM-16407-2|dip:DIP-187617E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001931"(uropod)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0050902"(leukocyte adhesive activation)|interpro:IPR026195|rcsb pdb:2EMT|reactome:R-MMU-202733|dip:DIP-59330N go:"GO:0070492"(oligosaccharide binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR033991|interpro:IPR035976|interpro:IPR001304(C-type lectin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002396("Selectin (CD62E/L/P antigen)")|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006954"(inflammatory response)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0033691"(sialic acid binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050901"(leukocyte tethering or rolling)|reactome:R-MMU-202733|refseq:NP_035475.1|refseq:XP_006496778.1|dip:DIP-59328N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:kgbj15PBqFxKCvQDD7kEm/4Rk4k10090 rogid:iPA+EqV56QAIMKxfD3yG28iBqpk10090 rigid:0fetn9Gj0hc8URhGFoUbv1vplRI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P15379 uniprotkb:Q00690 intact:EBI-7565891|intact:EBI-15579519|uniprotkb:Q62063|uniprotkb:Q62061|uniprotkb:Q05732|intact:UNK-5943644|uniprotkb:Q9QYX8|uniprotkb:Q62408|uniprotkb:Q99J14|uniprotkb:Q64296|uniprotkb:Q61395|uniprotkb:Q62060|uniprotkb:Q62062|uniprotkb:Q62409 intact:EBI-15852222 psi-mi:cd44_mouse(display_long)|uniprotkb:Phagocytic glycoprotein I(gene name synonym)|uniprotkb:Cd44(gene name)|psi-mi:Cd44(display_short)|uniprotkb:Ly-24(gene name synonym)|uniprotkb:Phagocytic glycoprotein 1(gene name synonym)|uniprotkb:HUTCH-I(gene name synonym)|uniprotkb:Extracellular matrix receptor III(gene name synonym)|uniprotkb:GP90 lymphocyte homing/adhesion receptor(gene name synonym)|uniprotkb:Hermes antigen(gene name synonym)|uniprotkb:Hyaluronate receptor(gene name synonym)|uniprotkb:Lymphocyte antigen 24(gene name synonym) psi-mi:lyam2_mouse(display_long)|uniprotkb:Sele(gene name)|psi-mi:Sele(display_short)|uniprotkb:Elam-1(gene name synonym)|uniprotkb:CD62 antigen-like family member E(gene name synonym)|uniprotkb:Endothelial leukocyte adhesion molecule 1(gene name synonym)|uniprotkb:Leukocyte-endothelial cell adhesion molecule 2(gene name synonym) psi-mi:"MI:0096"(pull down) Yago et al. (2010) pubmed:20439727|doi:10.1073/pnas.1003110107|imex:IM-16407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15852315|imex:IM-16407-3|dip:DIP-187618E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171257.1|refseq:NP_001034240.1|refseq:NP_001171258.1|refseq:NP_033981.2|refseq:NP_001171256.1|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0002246"(wound healing involved in inflammatory response)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005114"(type II transforming growth factor beta receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030214"(hyaluronan catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034238"(macrophage fusion)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0042110"(T cell activation)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060442"(branching involved in prostate gland morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070487"(monocyte aggregation)|go:"GO:1900625"(positive regulation of monocyte aggregation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR000538(Link)|interpro:IPR001231(CD44 antigen)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR043210|rcsb pdb:2JCP|rcsb pdb:2JCQ|rcsb pdb:5BZJ|rcsb pdb:2JCR|rcsb pdb:5BZK|rcsb pdb:5BZL|rcsb pdb:5BZM|rcsb pdb:5BZN|rcsb pdb:5BZO|rcsb pdb:2ZPY|rcsb pdb:5BZP|rcsb pdb:5BZQ|rcsb pdb:5BZR|rcsb pdb:5BZS|rcsb pdb:5BZT|rcsb pdb:4MRD|rcsb pdb:4MRE|rcsb pdb:4MRF|rcsb pdb:4MRG|rcsb pdb:4MRH|rcsb pdb:4NP2|rcsb pdb:4NP3|rcsb pdb:5BZC|rcsb pdb:5BZE|rcsb pdb:5BZF|rcsb pdb:5BZG|rcsb pdb:5BZH|rcsb pdb:5BZI|dip:DIP-29095N|reactome:R-MMU-1474228|reactome:R-MMU-202733|reactome:R-MMU-216083|reactome:R-MMU-2160916|reactome:R-MMU-6798695 go:"GO:0070492"(oligosaccharide binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR033991|interpro:IPR035976|interpro:IPR001304(C-type lectin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002396("Selectin (CD62E/L/P antigen)")|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006954"(inflammatory response)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0033691"(sialic acid binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050901"(leukocyte tethering or rolling)|reactome:R-MMU-202733|refseq:NP_035475.1|refseq:XP_006496778.1|dip:DIP-59328N psi-mi:"MI:0465"(dip) function:Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/11 rogid:1Rlb+aBsm9z0HJuB6Oz4Oilui1o10090 rogid:iPA+EqV56QAIMKxfD3yG28iBqpk10090 rigid:+cn1WrdQQzM7NbveAcpja7PKrVY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)