#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P52630 uniprotkb:Q77PU6 intact:EBI-1546963|uniprotkb:Q16430|uniprotkb:Q16431|uniprotkb:Q9UDL4|intact:EBI-10989287|uniprotkb:B4DLC7|uniprotkb:G3V2M6|ensembl:ENSP00000315768 intact:EBI-15849356 psi-mi:stat2_human(display_long)|uniprotkb:p113(gene name synonym)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:u90_hhv6z(display_long)|uniprotkb:U90(gene name)|psi-mi:U90(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jaworska et al. (2010) pubmed:20404187|doi:10.1073/pnas.0909951107|imex:IM-21484 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:36351(hhv6z)|taxid:36351("Human herpesvirus 6B (strain Z29)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15849365|imex:IM-21484-1|dip:DIP-191690E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005410.1|refseq:NP_938146.1|dip:DIP-38511N|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|mint:P52630|rcsb pdb:2KA4|rcsb pdb:6UX2|rcsb pdb:6WCZ|reactome:R-HSA-8854691|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191 interpro:IPR005507(Human herpesvirus 6 immediate early protein)|refseq:NP_050266.1|dip:DIP-60437N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 rogid:q8fxeAnBGrhNic34nOqZwvBY+GI36351 rigid:HV80uN2RZ+ZuQ2JT+j0gMg2Z51M false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52630 uniprotkb:Q77PU6 intact:EBI-1546963|uniprotkb:Q16430|uniprotkb:Q16431|uniprotkb:Q9UDL4|intact:EBI-10989287|uniprotkb:B4DLC7|uniprotkb:G3V2M6|ensembl:ENSP00000315768 intact:EBI-15849356 psi-mi:stat2_human(display_long)|uniprotkb:p113(gene name synonym)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:u90_hhv6z(display_long)|uniprotkb:U90(gene name)|psi-mi:U90(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jaworska et al. (2010) pubmed:20404187|doi:10.1073/pnas.0909951107|imex:IM-21484 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:36351(hhv6z)|taxid:36351("Human herpesvirus 6B (strain Z29)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15849382|imex:IM-21484-2|dip:DIP-191690E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005410.1|refseq:NP_938146.1|dip:DIP-38511N|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|mint:P52630|rcsb pdb:2KA4|rcsb pdb:6UX2|rcsb pdb:6WCZ|reactome:R-HSA-8854691|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191 interpro:IPR005507(Human herpesvirus 6 immediate early protein)|refseq:NP_050266.1|dip:DIP-60437N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 rogid:q8fxeAnBGrhNic34nOqZwvBY+GI36351 rigid:HV80uN2RZ+ZuQ2JT+j0gMg2Z51M false - sufficient binding region:1-540|myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q77PU6 uniprotkb:P52630-3 intact:EBI-15849356 intact:EBI-15849403|ensembl:ENSP00000315768 psi-mi:u90_hhv6z(display_long)|uniprotkb:U90(gene name)|psi-mi:U90(display_short) psi-mi:p52630-3(display_long)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short)|uniprotkb:p113(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jaworska et al. (2010) pubmed:20404187|doi:10.1073/pnas.0909951107|imex:IM-21484 taxid:36351(hhv6z)|taxid:36351("Human herpesvirus 6B (strain Z29)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15849409|imex:IM-21484-3|dip:DIP-191690E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005507(Human herpesvirus 6 immediate early protein)|refseq:NP_050266.1|dip:DIP-60437N intact:EBI-1546963(isoform-parent)|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:q8fxeAnBGrhNic34nOqZwvBY+GI36351 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 rigid:HV80uN2RZ+ZuQ2JT+j0gMg2Z51M false - sufficient binding region:1-397|sufficient binding region:111-851|green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)