#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q61644 uniprotkb:Q61644 intact:EBI-2255561|ensembl:ENSMUSP00000044168|ensembl:ENSMUSP00000094973|ensembl:ENSMUSP00000110523|ensembl:ENSMUSP00000155999|ensembl:ENSMUSP00000156003 intact:EBI-2255561|ensembl:ENSMUSP00000044168|ensembl:ENSMUSP00000094973|ensembl:ENSMUSP00000110523|ensembl:ENSMUSP00000155999|ensembl:ENSMUSP00000156003 psi-mi:pacn1_mouse(display_long)|uniprotkb:Pacsin(gene name synonym)|uniprotkb:Pacsin1(gene name)|psi-mi:Pacsin1(display_short)|uniprotkb:Syndapin-1(gene name synonym) psi-mi:pacn1_mouse(display_long)|uniprotkb:Pacsin(gene name synonym)|uniprotkb:Pacsin1(gene name)|psi-mi:Pacsin1(display_short)|uniprotkb:Syndapin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Rao et al. (2010) pubmed:20404169|doi:10.1073/pnas.1003478107|imex:IM-16394 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15849073|imex:IM-16394-1|dip:DIP-187595E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011244733.1|refseq:NP_035991.1|refseq:NP_848142.1|refseq:NP_001273672.1|refseq:NP_001273673.1|refseq:XP_006524289.1|dip:DIP-53108N|ensembl:ENSMUSG00000040276(gene)|ensembl:ENSMUST00000045896(transcript)|ensembl:ENSMUST00000097360(transcript)|ensembl:ENSMUST00000114873(transcript)|ensembl:ENSMUST00000231669(transcript)|ensembl:ENSMUST00000232437(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028518|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037454|mint:Q61644|rcsb pdb:2X3V|rcsb pdb:2X3W|rcsb pdb:2X3X|reactome:R-MMU-8856828 refseq:XP_011244733.1|refseq:NP_035991.1|refseq:NP_848142.1|refseq:NP_001273672.1|refseq:NP_001273673.1|refseq:XP_006524289.1|dip:DIP-53108N|ensembl:ENSMUSG00000040276(gene)|ensembl:ENSMUST00000045896(transcript)|ensembl:ENSMUST00000097360(transcript)|ensembl:ENSMUST00000114873(transcript)|ensembl:ENSMUST00000231669(transcript)|ensembl:ENSMUST00000232437(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028518|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037454|mint:Q61644|rcsb pdb:2X3V|rcsb pdb:2X3W|rcsb pdb:2X3X|reactome:R-MMU-8856828 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lHj61yfdrObrknZUNqDUPgGI4cE10090 rogid:lHj61yfdrObrknZUNqDUPgGI4cE10090 rigid:UN4I9BZADTpGnzj95IugkqGWrmA false binding-associated region:379-441|glutathione s tranferase tag:n-n|mutation decreasing interaction strength:400-400,394-394|mutation decreasing interaction:397-397,396-396 binding-associated region:1-337 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q61644 uniprotkb:Q61644 intact:EBI-2255561|ensembl:ENSMUSP00000044168|ensembl:ENSMUSP00000094973|ensembl:ENSMUSP00000110523|ensembl:ENSMUSP00000155999|ensembl:ENSMUSP00000156003 intact:EBI-2255561|ensembl:ENSMUSP00000044168|ensembl:ENSMUSP00000094973|ensembl:ENSMUSP00000110523|ensembl:ENSMUSP00000155999|ensembl:ENSMUSP00000156003 psi-mi:pacn1_mouse(display_long)|uniprotkb:Pacsin(gene name synonym)|uniprotkb:Pacsin1(gene name)|psi-mi:Pacsin1(display_short)|uniprotkb:Syndapin-1(gene name synonym) psi-mi:pacn1_mouse(display_long)|uniprotkb:Pacsin(gene name synonym)|uniprotkb:Pacsin1(gene name)|psi-mi:Pacsin1(display_short)|uniprotkb:Syndapin-1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Rao et al. (2010) pubmed:20404169|doi:10.1073/pnas.1003478107|imex:IM-16394 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15849104|imex:IM-16394-2|dip:DIP-187595E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011244733.1|refseq:NP_035991.1|refseq:NP_848142.1|refseq:NP_001273672.1|refseq:NP_001273673.1|refseq:XP_006524289.1|dip:DIP-53108N|ensembl:ENSMUSG00000040276(gene)|ensembl:ENSMUST00000045896(transcript)|ensembl:ENSMUST00000097360(transcript)|ensembl:ENSMUST00000114873(transcript)|ensembl:ENSMUST00000231669(transcript)|ensembl:ENSMUST00000232437(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028518|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037454|mint:Q61644|rcsb pdb:2X3V|rcsb pdb:2X3W|rcsb pdb:2X3X|reactome:R-MMU-8856828 refseq:XP_011244733.1|refseq:NP_035991.1|refseq:NP_848142.1|refseq:NP_001273672.1|refseq:NP_001273673.1|refseq:XP_006524289.1|dip:DIP-53108N|ensembl:ENSMUSG00000040276(gene)|ensembl:ENSMUST00000045896(transcript)|ensembl:ENSMUST00000097360(transcript)|ensembl:ENSMUST00000114873(transcript)|ensembl:ENSMUST00000231669(transcript)|ensembl:ENSMUST00000232437(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028518|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037454|mint:Q61644|rcsb pdb:2X3V|rcsb pdb:2X3W|rcsb pdb:2X3X|reactome:R-MMU-8856828 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:lHj61yfdrObrknZUNqDUPgGI4cE10090 rogid:lHj61yfdrObrknZUNqDUPgGI4cE10090 rigid:V4llcwpO58922+DJ0dsrT8JiNes false binding-associated region:1-337 binding-associated region:1-337 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61644 uniprotkb:P49418-1 intact:EBI-2255561|ensembl:ENSMUSP00000044168|ensembl:ENSMUSP00000094973|ensembl:ENSMUSP00000110523|ensembl:ENSMUSP00000155999|ensembl:ENSMUSP00000156003 intact:EBI-15849122|ensembl:ENSP00000348602 psi-mi:pacn1_mouse(display_long)|uniprotkb:Pacsin(gene name synonym)|uniprotkb:Pacsin1(gene name)|psi-mi:Pacsin1(display_short)|uniprotkb:Syndapin-1(gene name synonym) psi-mi:p49418-1(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)|uniprotkb:128 kDa(isoform synonym) psi-mi:"MI:0096"(pull down) Rao et al. (2010) pubmed:20404169|doi:10.1073/pnas.1003478107|imex:IM-16394 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15849129|imex:IM-16394-3|dip:DIP-187599E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011244733.1|refseq:NP_035991.1|refseq:NP_848142.1|refseq:NP_001273672.1|refseq:NP_001273673.1|refseq:XP_006524289.1|dip:DIP-53108N|ensembl:ENSMUSG00000040276(gene)|ensembl:ENSMUST00000045896(transcript)|ensembl:ENSMUST00000097360(transcript)|ensembl:ENSMUST00000114873(transcript)|ensembl:ENSMUST00000231669(transcript)|ensembl:ENSMUST00000232437(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028518|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037454|mint:Q61644|rcsb pdb:2X3V|rcsb pdb:2X3W|rcsb pdb:2X3X|reactome:R-MMU-8856828 intact:EBI-7121510(isoform-parent)|ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lHj61yfdrObrknZUNqDUPgGI4cE10090 rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 rigid:V6tqZP+e6kLPRkvgbO+x6N8rLdc false binding-associated region:1-337 binding-associated region:546-695|glutathione s tranferase tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P49418-1 uniprotkb:P49418-1 intact:EBI-15849122|ensembl:ENSP00000348602 intact:EBI-15849122|ensembl:ENSP00000348602 psi-mi:p49418-1(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)|uniprotkb:128 kDa(isoform synonym) psi-mi:p49418-1(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)|uniprotkb:128 kDa(isoform synonym) psi-mi:"MI:0096"(pull down) Rao et al. (2010) pubmed:20404169|doi:10.1073/pnas.1003478107|imex:IM-16394 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15849154|imex:IM-16394-4|dip:DIP-187597E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7121510(isoform-parent)|ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript) intact:EBI-7121510(isoform-parent)|ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 rigid:7BgYiFoUdnyRnaE/zkBN9zM1tMw false binding-associated region:1-245 binding-associated region:546-695|glutathione s tranferase tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q61644 uniprotkb:Q61644 intact:EBI-2255561|ensembl:ENSMUSP00000044168|ensembl:ENSMUSP00000094973|ensembl:ENSMUSP00000110523|ensembl:ENSMUSP00000155999|ensembl:ENSMUSP00000156003 intact:EBI-2255561|ensembl:ENSMUSP00000044168|ensembl:ENSMUSP00000094973|ensembl:ENSMUSP00000110523|ensembl:ENSMUSP00000155999|ensembl:ENSMUSP00000156003 psi-mi:pacn1_mouse(display_long)|uniprotkb:Pacsin(gene name synonym)|uniprotkb:Pacsin1(gene name)|psi-mi:Pacsin1(display_short)|uniprotkb:Syndapin-1(gene name synonym) psi-mi:pacn1_mouse(display_long)|uniprotkb:Pacsin(gene name synonym)|uniprotkb:Pacsin1(gene name)|psi-mi:Pacsin1(display_short)|uniprotkb:Syndapin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Rao et al. (2010) pubmed:20404169|doi:10.1073/pnas.1003478107|imex:IM-16394 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15849179|imex:IM-16394-5|dip:DIP-187595E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011244733.1|refseq:NP_035991.1|refseq:NP_848142.1|refseq:NP_001273672.1|refseq:NP_001273673.1|refseq:XP_006524289.1|dip:DIP-53108N|ensembl:ENSMUSG00000040276(gene)|ensembl:ENSMUST00000045896(transcript)|ensembl:ENSMUST00000097360(transcript)|ensembl:ENSMUST00000114873(transcript)|ensembl:ENSMUST00000231669(transcript)|ensembl:ENSMUST00000232437(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028518|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037454|mint:Q61644|rcsb pdb:2X3V|rcsb pdb:2X3W|rcsb pdb:2X3X|reactome:R-MMU-8856828 refseq:XP_011244733.1|refseq:NP_035991.1|refseq:NP_848142.1|refseq:NP_001273672.1|refseq:NP_001273673.1|refseq:XP_006524289.1|dip:DIP-53108N|ensembl:ENSMUSG00000040276(gene)|ensembl:ENSMUST00000045896(transcript)|ensembl:ENSMUST00000097360(transcript)|ensembl:ENSMUST00000114873(transcript)|ensembl:ENSMUST00000231669(transcript)|ensembl:ENSMUST00000232437(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028518|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037454|mint:Q61644|rcsb pdb:2X3V|rcsb pdb:2X3W|rcsb pdb:2X3X|reactome:R-MMU-8856828 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lHj61yfdrObrknZUNqDUPgGI4cE10090 rogid:lHj61yfdrObrknZUNqDUPgGI4cE10090 rigid:UN4I9BZADTpGnzj95IugkqGWrmA false binding-associated region:379-441|glutathione s tranferase tag:n-n binding-associated region:1-337|mutation disrupting interaction:148-148,146-146,145-145 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q99962 uniprotkb:Q99962 intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618 intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618 psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym) psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym) psi-mi:"MI:0096"(pull down) Rao et al. (2010) pubmed:20404169|doi:10.1073/pnas.1003478107|imex:IM-16394 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15849207|imex:IM-16394-6|dip:DIP-187596E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606 rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606 rigid:SRLcWLVc6Dik1EhoEJbey67duPQ false binding-associated region:1-256 binding-associated region:245-352|glutathione s tranferase tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q05193 uniprotkb:Q61644 intact:EBI-713135|uniprotkb:A6NLM6|uniprotkb:Q5SYX0|uniprotkb:Q5SYX2|uniprotkb:Q6P3T6|uniprotkb:Q86VD2|ensembl:ENSP00000362014 intact:EBI-2255561|ensembl:ENSMUSP00000044168|ensembl:ENSMUSP00000094973|ensembl:ENSMUSP00000110523|ensembl:ENSMUSP00000155999|ensembl:ENSMUSP00000156003 psi-mi:dyn1_human(display_long)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short)|uniprotkb:DNM(gene name synonym) psi-mi:pacn1_mouse(display_long)|uniprotkb:Pacsin(gene name synonym)|uniprotkb:Pacsin1(gene name)|psi-mi:Pacsin1(display_short)|uniprotkb:Syndapin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Rao et al. (2010) pubmed:20404169|doi:10.1073/pnas.1003478107|imex:IM-16394 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15849230|imex:IM-16394-7|dip:DIP-187600E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005336.1|refseq:NP_004399.2|refseq:NP_001275666.1|refseq:NP_001275667.1|refseq:NP_001275668.1|refseq:XP_005251825.1|refseq:XP_005251826.1|refseq:XP_016869860.1|dip:DIP-36242N|ensembl:ENSG00000106976(gene)|ensembl:ENST00000372923(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:Q05193|rcsb pdb:1DYN|rcsb pdb:2DYN|rcsb pdb:2X2E|rcsb pdb:2X2F|rcsb pdb:3SNH|rcsb pdb:3ZYC|rcsb pdb:3ZYS|rcsb pdb:4UUD|rcsb pdb:4UUK|rcsb pdb:5D3Q|rcsb pdb:6DLU|rcsb pdb:6DLV|rcsb pdb:6S9A|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-437239|reactome:R-HSA-8856828|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane) refseq:XP_011244733.1|refseq:NP_035991.1|refseq:NP_848142.1|refseq:NP_001273672.1|refseq:NP_001273673.1|refseq:XP_006524289.1|dip:DIP-53108N|ensembl:ENSMUSG00000040276(gene)|ensembl:ENSMUST00000045896(transcript)|ensembl:ENSMUST00000097360(transcript)|ensembl:ENSMUST00000114873(transcript)|ensembl:ENSMUST00000231669(transcript)|ensembl:ENSMUST00000232437(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028518|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037454|mint:Q61644|rcsb pdb:2X3V|rcsb pdb:2X3W|rcsb pdb:2X3X|reactome:R-MMU-8856828 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:uiP8CXhKWQaP2GIAZULJTLqwGLs9606 rogid:lHj61yfdrObrknZUNqDUPgGI4cE10090 rigid:Atd5b1iwz/jaDFL4NgYnp9RRM4o false binding-associated region:509-864 binding-associated region:379-441|glutathione s tranferase tag:n-n|mutation decreasing interaction:400-400|mutation decreasing interaction:434-434|mutation decreasing interaction strength:400-400,394-394 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q61644 uniprotkb:Q99962 intact:EBI-2255561|ensembl:ENSMUSP00000044168|ensembl:ENSMUSP00000094973|ensembl:ENSMUSP00000110523|ensembl:ENSMUSP00000155999|ensembl:ENSMUSP00000156003 intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618 psi-mi:pacn1_mouse(display_long)|uniprotkb:Pacsin(gene name synonym)|uniprotkb:Pacsin1(gene name)|psi-mi:Pacsin1(display_short)|uniprotkb:Syndapin-1(gene name synonym) psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym) psi-mi:"MI:0096"(pull down) Rao et al. (2010) pubmed:20404169|doi:10.1073/pnas.1003478107|imex:IM-16394 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15849262|imex:IM-16394-8|dip:DIP-187598E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011244733.1|refseq:NP_035991.1|refseq:NP_848142.1|refseq:NP_001273672.1|refseq:NP_001273673.1|refseq:XP_006524289.1|dip:DIP-53108N|ensembl:ENSMUSG00000040276(gene)|ensembl:ENSMUST00000045896(transcript)|ensembl:ENSMUST00000097360(transcript)|ensembl:ENSMUST00000114873(transcript)|ensembl:ENSMUST00000231669(transcript)|ensembl:ENSMUST00000232437(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028518|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037454|mint:Q61644|rcsb pdb:2X3V|rcsb pdb:2X3W|rcsb pdb:2X3X|reactome:R-MMU-8856828 go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lHj61yfdrObrknZUNqDUPgGI4cE10090 rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606 rigid:DTS1+/HbTsCFzTHaIbHE9qNNsII false binding-associated region:1-337 binding-associated region:245-352|glutathione s tranferase tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)