#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q960X8	uniprotkb:P08953	intact:EBI-90175|uniprotkb:A4V018|uniprotkb:Q8IGU6|uniprotkb:Q9VQF2|uniprotkb:Q9VQF3|ensemblmetazoa:FBpp0088691|ensemblmetazoa:FBpp0088692	intact:EBI-143610|uniprotkb:A4V3G7|uniprotkb:A8WHK7|uniprotkb:Q8MRF3|uniprotkb:Q9VBB8|ensemblmetazoa:FBpp0084431|ensemblmetazoa:FBpp0303188	psi-mi:hrs_drome(display_long)|uniprotkb:Hrs(gene name)|psi-mi:Hrs(display_short)|uniprotkb:CG2903(orf name)	psi-mi:toll_drome(display_long)|uniprotkb:Tl(gene name)|psi-mi:Tl(display_short)|uniprotkb:CG5490(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Huang et al. (2010)	pubmed:20404143|doi:10.1073/pnas.1004031107|imex:IM-16391	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15848965|imex:IM-16391-1|dip:DIP-187593E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_525099.3|refseq:NP_722830.2|refseq:NP_722831.1|flybase:FBgn0031450|rcsb pdb:1DVP|reactome:R-DME-182971|reactome:R-DME-432720|reactome:R-DME-5689880|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9013420|reactome:R-DME-917729|reactome:R-DME-9706019|ensemblmetazoa:FBgn0031450(gene)|ensemblmetazoa:FBtr0089750(transcript)|ensemblmetazoa:FBtr0089751(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0016322"(neuron remodeling)|go:"GO:0031623"(receptor internalization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0120177"(negative regulation of torso signaling pathway)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|dip:DIP-32844N	refseq:NP_524518.1|refseq:NP_733166.1|flybase:FBgn0262473|dip:DIP-34358N|ensemblmetazoa:FBgn0262473(gene)|ensemblmetazoa:FBtr0085059(transcript)|ensemblmetazoa:FBtr0330155(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002229"(defense response to oomycetes)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007507"(heart development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009597"(detection of virus)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0019955"(cytokine binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046790"(virion binding)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0070976"(TIR domain binding)|go:"GO:1902875"(regulation of embryonic pattern specification)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR026906|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4ARN|rcsb pdb:4ARR|rcsb pdb:4BV4|rcsb pdb:4LXR|rcsb pdb:4LXS|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/06	2017/08/10	rogid:hi+tD4OPAkcdwQMOQQ7YyDuK3+87227	rogid:6nIbDMNS71rQ+CzvUkspyPjTd707227	rigid:p0LM/pp+BvkNYgf8vJfsW/ygIo0	false	flag tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q960X8	uniprotkb:Q9VUH6	intact:EBI-90175|uniprotkb:A4V018|uniprotkb:Q8IGU6|uniprotkb:Q9VQF2|uniprotkb:Q9VQF3|ensemblmetazoa:FBpp0088691|ensemblmetazoa:FBpp0088692	intact:EBI-15848934|ensemblmetazoa:FBpp0075450	psi-mi:hrs_drome(display_long)|uniprotkb:Hrs(gene name)|psi-mi:Hrs(display_short)|uniprotkb:CG2903(orf name)	psi-mi:q9vuh6_drome(display_long)|uniprotkb:mop(gene name)|psi-mi:mop(display_short)|uniprotkb:Dmel\CG9311(gene name synonym)|uniprotkb:Mop(gene name synonym)|uniprotkb:sfv(gene name synonym)|uniprotkb:Dmel_CG9311(orf name)|uniprotkb:CG9311(orf name)|uniprotkb:MOP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Huang et al. (2010)	pubmed:20404143|doi:10.1073/pnas.1004031107|imex:IM-16391	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15848965|imex:IM-16391-1|dip:DIP-187593E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_525099.3|refseq:NP_722830.2|refseq:NP_722831.1|flybase:FBgn0031450|rcsb pdb:1DVP|reactome:R-DME-182971|reactome:R-DME-432720|reactome:R-DME-5689880|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9013420|reactome:R-DME-917729|reactome:R-DME-9706019|ensemblmetazoa:FBgn0031450(gene)|ensemblmetazoa:FBtr0089750(transcript)|ensemblmetazoa:FBtr0089751(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0016322"(neuron remodeling)|go:"GO:0031623"(receptor internalization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0120177"(negative regulation of torso signaling pathway)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|dip:DIP-32844N	go:"GO:0007299"(ovarian follicle cell-cell adhesion)|go:"GO:0007419"(ventral cord development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0051225"(spindle assembly)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR029021|interpro:IPR038499|go:"GO:0005829"(cytosol)|ensemblmetazoa:FBgn0036448(gene)|ensemblmetazoa:FBtr0075700(transcript)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005768"(endosome)|refseq:NP_648722.2|flybase:FBgn0036448|dip:DIP-59323N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/06	2017/08/10	rogid:hi+tD4OPAkcdwQMOQQ7YyDuK3+87227	rogid:+gZ01/+CiRqz25qmw8M1BYgFQG87227	rigid:p0LM/pp+BvkNYgf8vJfsW/ygIo0	false	flag tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)