#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P09616 uniprotkb:P09616 intact:EBI-15848589 intact:EBI-15848589 psi-mi:hla_staau(display_long)|uniprotkb:hly(gene name)|psi-mi:hly(display_short)|uniprotkb:hla(gene name synonym)|uniprotkb:Alpha-toxin(gene name synonym) psi-mi:hla_staau(display_long)|uniprotkb:hly(gene name)|psi-mi:hly(display_short)|uniprotkb:hla(gene name synonym)|uniprotkb:Alpha-toxin(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Banerjee et al. (2010) pubmed:20400691|doi:10.1073/pnas.0914229107|imex:IM-16390 taxid:1280(staau)|taxid:1280(Staphylococcus aureus) taxid:1280(staau)|taxid:1280(Staphylococcus aureus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15848614|imex:IM-16390-1|dip:DIP-187592E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR003963(Bi-component toxin, staphylococci)|interpro:IPR005831(Aerolysin/haemolysin toxin, conserved site)|interpro:IPR016183(Leukocidin/porin)|interpro:IPR036435|rcsb pdb:3M2L|rcsb pdb:3M3R|rcsb pdb:3M4D|rcsb pdb:3M4E|rcsb pdb:4IDJ|rcsb pdb:4YHD|rcsb pdb:6U3T|rcsb pdb:6U49|rcsb pdb:6U4P|rcsb pdb:7AHL|rcsb pdb:7O1Q|reactome:R-HSA-9660826|reactome:R-HSA-844456|dip:DIP-59322N go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR003963(Bi-component toxin, staphylococci)|interpro:IPR005831(Aerolysin/haemolysin toxin, conserved site)|interpro:IPR016183(Leukocidin/porin)|interpro:IPR036435|rcsb pdb:3M2L|rcsb pdb:3M3R|rcsb pdb:3M4D|rcsb pdb:3M4E|rcsb pdb:4IDJ|rcsb pdb:4YHD|rcsb pdb:6U3T|rcsb pdb:6U49|rcsb pdb:6U4P|rcsb pdb:7AHL|rcsb pdb:7O1Q|reactome:R-HSA-9660826|reactome:R-HSA-844456|dip:DIP-59322N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:0BR0y0GDnhSuti8YNFYvf2RGbqo1280 rogid:0BR0y0GDnhSuti8YNFYvf2RGbqo1280 rigid:kQEH0EB/DU5+4yXuaww0VLUnFWw false binding-associated region:27-319 binding-associated region:27-319 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09616 uniprotkb:P09616 intact:EBI-15848589 intact:EBI-15848589 psi-mi:hla_staau(display_long)|uniprotkb:hly(gene name)|psi-mi:hly(display_short)|uniprotkb:hla(gene name synonym)|uniprotkb:Alpha-toxin(gene name synonym) psi-mi:hla_staau(display_long)|uniprotkb:hly(gene name)|psi-mi:hly(display_short)|uniprotkb:hla(gene name synonym)|uniprotkb:Alpha-toxin(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Banerjee et al. (2010) pubmed:20400691|doi:10.1073/pnas.0914229107|imex:IM-16390 taxid:1280(staau)|taxid:1280(Staphylococcus aureus) taxid:1280(staau)|taxid:1280(Staphylococcus aureus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15848636|imex:IM-16390-2|dip:DIP-187592E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR003963(Bi-component toxin, staphylococci)|interpro:IPR005831(Aerolysin/haemolysin toxin, conserved site)|interpro:IPR016183(Leukocidin/porin)|interpro:IPR036435|rcsb pdb:3M2L|rcsb pdb:3M3R|rcsb pdb:3M4D|rcsb pdb:3M4E|rcsb pdb:4IDJ|rcsb pdb:4YHD|rcsb pdb:6U3T|rcsb pdb:6U49|rcsb pdb:6U4P|rcsb pdb:7AHL|rcsb pdb:7O1Q|reactome:R-HSA-9660826|reactome:R-HSA-844456|dip:DIP-59322N go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR003963(Bi-component toxin, staphylococci)|interpro:IPR005831(Aerolysin/haemolysin toxin, conserved site)|interpro:IPR016183(Leukocidin/porin)|interpro:IPR036435|rcsb pdb:3M2L|rcsb pdb:3M3R|rcsb pdb:3M4D|rcsb pdb:3M4E|rcsb pdb:4IDJ|rcsb pdb:4YHD|rcsb pdb:6U3T|rcsb pdb:6U49|rcsb pdb:6U4P|rcsb pdb:7AHL|rcsb pdb:7O1Q|reactome:R-HSA-9660826|reactome:R-HSA-844456|dip:DIP-59322N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/06 rogid:0BR0y0GDnhSuti8YNFYvf2RGbqo1280 rogid:0BR0y0GDnhSuti8YNFYvf2RGbqo1280 rigid:kQEH0EB/DU5+4yXuaww0VLUnFWw false binding-associated region:27-319 binding-associated region:27-319 7 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09616 uniprotkb:P09616 intact:EBI-15848589 intact:EBI-15848589 psi-mi:hla_staau(display_long)|uniprotkb:hly(gene name)|psi-mi:hly(display_short)|uniprotkb:hla(gene name synonym)|uniprotkb:Alpha-toxin(gene name synonym) psi-mi:hla_staau(display_long)|uniprotkb:hly(gene name)|psi-mi:hly(display_short)|uniprotkb:hla(gene name synonym)|uniprotkb:Alpha-toxin(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Banerjee et al. (2010) pubmed:20400691|doi:10.1073/pnas.0914229107|imex:IM-16390 taxid:1280(staau)|taxid:1280(Staphylococcus aureus) taxid:1280(staau)|taxid:1280(Staphylococcus aureus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15848654|imex:IM-16390-3|dip:DIP-187592E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR003963(Bi-component toxin, staphylococci)|interpro:IPR005831(Aerolysin/haemolysin toxin, conserved site)|interpro:IPR016183(Leukocidin/porin)|interpro:IPR036435|rcsb pdb:3M2L|rcsb pdb:3M3R|rcsb pdb:3M4D|rcsb pdb:3M4E|rcsb pdb:4IDJ|rcsb pdb:4YHD|rcsb pdb:6U3T|rcsb pdb:6U49|rcsb pdb:6U4P|rcsb pdb:7AHL|rcsb pdb:7O1Q|reactome:R-HSA-9660826|reactome:R-HSA-844456|dip:DIP-59322N go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR003963(Bi-component toxin, staphylococci)|interpro:IPR005831(Aerolysin/haemolysin toxin, conserved site)|interpro:IPR016183(Leukocidin/porin)|interpro:IPR036435|rcsb pdb:3M2L|rcsb pdb:3M3R|rcsb pdb:3M4D|rcsb pdb:3M4E|rcsb pdb:4IDJ|rcsb pdb:4YHD|rcsb pdb:6U3T|rcsb pdb:6U49|rcsb pdb:6U4P|rcsb pdb:7AHL|rcsb pdb:7O1Q|reactome:R-HSA-9660826|reactome:R-HSA-844456|dip:DIP-59322N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:0BR0y0GDnhSuti8YNFYvf2RGbqo1280 rogid:0BR0y0GDnhSuti8YNFYvf2RGbqo1280 rigid:kQEH0EB/DU5+4yXuaww0VLUnFWw false binding-associated region:27-319|35s radiolabel:?-? binding-associated region:27-319|35s radiolabel:?-? - 0 psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)