#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P20309	uniprotkb:P49798	intact:EBI-2687785|uniprotkb:Q0VAJ8|uniprotkb:Q9HB60|uniprotkb:Q4QRI3|uniprotkb:Q5VXY2|ensembl:ENSP00000255380|ensembl:ENSP00000482377|ensembl:ENSP00000502013|ensembl:ENSP00000502349|ensembl:ENSP00000502667	intact:EBI-9688865|uniprotkb:A7XA56|uniprotkb:A7XA58|uniprotkb:A7XA59|uniprotkb:A7YVV7|uniprotkb:B1APZ3|ensembl:ENSP00000356885	psi-mi:acm3_human(display_long)|uniprotkb:CHRM3(gene name)|psi-mi:CHRM3(display_short)	psi-mi:rgs4_human(display_long)|uniprotkb:RGS4(gene name)|psi-mi:RGS4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ruiz et al. (2010)	pubmed:20385802|doi:10.1073/pnas.1003655107|imex:IM-16387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15847481|imex:IM-16387-1|dip:DIP-187586E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011542343.1|refseq:XP_011542345.1|refseq:XP_011542346.1|refseq:XP_011542348.1|refseq:XP_011542349.1|refseq:NP_000731.1|refseq:NP_001334645.1|refseq:XP_005273089.1|ensembl:ENSG00000133019(gene)|ensembl:ENST00000255380(transcript)|ensembl:ENST00000615928(transcript)|ensembl:ENST00000675184(transcript)|ensembl:ENST00000676433(transcript)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|ensembl:ENST00000676153(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032412"(regulation of ion transmembrane transporter activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046541"(saliva secretion)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000995(Muscarinic acetylcholine receptor)|interpro:IPR001183(Muscarinic acetylcholine receptor M3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P20309|rcsb pdb:2CSA|reactome:R-HSA-390648|reactome:R-HSA-399997|reactome:R-HSA-416476|refseq:XP_016855641.1|refseq:XP_016855642.1|refseq:XP_016855643.1|refseq:XP_016855644.1|refseq:XP_016855645.1|refseq:XP_016855646.1|refseq:XP_016855647.1|refseq:XP_016855648.1|refseq:XP_016855649.1|refseq:XP_016855650.1|refseq:XP_016855651.1|refseq:XP_016855652.1|dip:DIP-44291N	dip:DIP-59092N|refseq:NP_001095915.1|refseq:NP_001106851.1|refseq:NP_001106852.1|refseq:NP_005604.1|ensembl:ENSG00000117152(gene)|ensembl:ENST00000367909(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0043278"(response to morphine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045471"(response to ethanol)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060160"(negative regulation of dopamine receptor signaling pathway)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0110053"(regulation of actin filament organization)|go:"GO:1900924"(negative regulation of glycine import across plasma membrane)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR034952|interpro:IPR034953|interpro:IPR036305|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-418597	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2017/08/06	2017/08/10	rogid:/arNBsrkXe4KcqIqBw4BEwYZHt49606	rogid:txTUJ5lIHkBDZ4palUD4jGSZAA89606	rigid:OWEho7DmYAg+lbzhEgKG06PtQBQ	false	ha tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)