#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O52302 uniprotkb:P07900 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022383|imex:IM-25964-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/04/02 2017/04/03 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 rigid:6gwmqFM30hDKiiPcHz/L3EwdB58 false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O52302 uniprotkb:P08238 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022383|imex:IM-25964-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/04/02 2017/04/03 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 rigid:6gwmqFM30hDKiiPcHz/L3EwdB58 false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O52302 uniprotkb:P08195 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022383|imex:IM-25964-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240 - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/04/02 2017/04/03 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606 rigid:6gwmqFM30hDKiiPcHz/L3EwdB58 false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O52302 uniprotkb:P62979 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022383|imex:IM-25964-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1 - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/04/02 2017/04/03 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606 rigid:6gwmqFM30hDKiiPcHz/L3EwdB58 false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O52302 uniprotkb:P08195 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022401|imex:IM-25964-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240 - - - figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606 rigid:TaSgkNFpMY426/PB9oRcUQdV4TI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O52302 uniprotkb:P08962 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-762053|uniprotkb:Q5TZP3|uniprotkb:Q9UCG6|uniprotkb:Q8N6Z9|uniprotkb:F8VZE2|ensembl:ENSP00000257857|ensembl:ENSP00000393502|ensembl:ENSP00000447730|ensembl:ENSP00000449337 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:cd63_human(display_long)|uniprotkb:Melanoma-associated antigen ME491(gene name synonym)|uniprotkb:Ocular melanoma-associated antigen(gene name synonym)|uniprotkb:OMA81H(gene name synonym)|uniprotkb:Granulophysin(gene name synonym)|uniprotkb:Tetraspanin-30(gene name synonym)|uniprotkb:Lysosomal-associated membrane protein 3(gene name synonym)|uniprotkb:CD63(gene name)|psi-mi:CD63(display_short)|uniprotkb:MLA1(gene name synonym)|uniprotkb:TSPAN30(gene name synonym)|uniprotkb:Lysosome integral membrane protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022405|imex:IM-25964-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_001771.1|refseq:NP_001244330.1|refseq:NP_001244318.1|refseq:NP_001244319.1|refseq:NP_001244320.1|refseq:NP_001244329.1|refseq:NP_001254627.1|refseq:NP_001244321.1|ensembl:ENSG00000135404(gene)|ensembl:ENST00000257857(transcript)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042028|mint:P08962|reactome:R-HSA-114608|reactome:R-HSA-6798695|go:"GO:0097487"(multivesicular body, internal vesicle)|ensembl:ENST00000420846(transcript)|ensembl:ENST00000549117(transcript)|ensembl:ENST00000552692(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016477"(cell migration)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048757"(pigment granule maturation)|go:"GO:0070062"(extracellular exosome) - - - figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:stCGi5kkTMIdO84qSwjmjpUwwvs9606 rigid:B25z22mO26sifMakaprCCNTz+78 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O52302 uniprotkb:P40967 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-14022409|uniprotkb:B3KS57|uniprotkb:B7Z6D7|uniprotkb:Q12763|uniprotkb:Q14448|uniprotkb:Q14817|uniprotkb:Q16565|ensembl:ENSP00000447374|ensembl:ENSP00000448828|ensembl:ENSP00000449690 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:pmel_human(display_long)|uniprotkb:PMEL(gene name)|psi-mi:PMEL(display_short)|uniprotkb:D12S53E(gene name synonym)|uniprotkb:PMEL17(gene name synonym)|uniprotkb:SILV(gene name synonym)|uniprotkb:ME20-M(gene name synonym)|uniprotkb:Melanocyte protein Pmel 17(gene name synonym)|uniprotkb:Melanocytes lineage-specific antigen GP100(gene name synonym)|uniprotkb:Melanoma-associated ME20 antigen(gene name synonym)|uniprotkb:P1(gene name synonym)|uniprotkb:P100(gene name synonym)|uniprotkb:Premelanosome protein(gene name synonym)|uniprotkb:Silver locus protein homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022459|imex:IM-25964-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_001186982.1|refseq:NP_001186983.1|refseq:NP_001307050.1|refseq:NP_001307051.1|refseq:NP_008859.1|refseq:XP_006719632.1|refseq:XP_011536987.1|ensembl:ENSG00000185664(gene)|ensembl:ENST00000548493(transcript)|ensembl:ENST00000548747(transcript)|ensembl:ENST00000552882(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0032438"(melanosome organization)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|interpro:IPR000601(PKD)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR022409|interpro:IPR035986|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:3CC5|rcsb pdb:4IS6|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|dip:DIP-48937N - - - figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:m4tPA2808oiUqUUr4R5X9F8pTPo9606 rigid:CpIEcCMSB/ZOzNqzDSToaMqrm5c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O52302 uniprotkb:Q96DB9 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-14022463|uniprotkb:B7WNZ8|uniprotkb:Q6UW44|uniprotkb:Q9HC34|uniprotkb:Q9P039|ensembl:ENSP00000344254|ensembl:ENSP00000376053|ensembl:ENSP00000393848|ensembl:ENSP00000443390|ensembl:ENSP00000465667 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:fxyd5_human(display_long)|uniprotkb:FXYD5(gene name)|psi-mi:FXYD5(display_short)|uniprotkb:DYSAD(gene name synonym)|uniprotkb:IWU1(gene name synonym)|uniprotkb:HSPC113(orf name)|uniprotkb:UNQ2561/PRO6241(orf name)|uniprotkb:Dysadherin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022502|imex:IM-25964-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_001158077.1|refseq:NP_001307842.1|refseq:NP_054883.3|refseq:NP_659003.1|ensembl:ENSG00000089327(gene)|ensembl:ENST00000342879(transcript)|ensembl:ENST00000392219(transcript)|ensembl:ENST00000423817(transcript)|ensembl:ENST00000541435(transcript)|ensembl:ENST00000590686(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030033"(microvillus assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0046588"(negative regulation of calcium-dependent cell-cell adhesion)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000272(Ion-transport regulator, FXYD region) - - - figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:pJb+sLBO4y8knVsw+CkezSpZCCk9606 rigid:5uR1XzvzBPkLPCjufpd+5IokSHw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O52302 uniprotkb:P58340 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-721328|intact:EBI-767466|uniprotkb:E9PEU9|uniprotkb:Q2TLE5|uniprotkb:Q8N8F8|uniprotkb:Q96MH1|uniprotkb:Q2TLE3|ensembl:ENSP00000348157 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:mlf1_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 1(gene name synonym)|uniprotkb:MLF1(gene name)|psi-mi:MLF1(display_short) psi-mi:"MI:0018"(two hybrid) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022506|imex:IM-25964-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_071888.1|refseq:NP_001182361.1|refseq:NP_001182362.1|refseq:NP_001182363.1|refseq:XP_011511154.1|refseq:NP_001123628.1|refseq:NP_001123629.1|ensembl:ENSP00000348157|ensembl:ENST00000359117|ensembl:ENSP00000352025|ensembl:ENST00000392822|ensembl:ENSP00000376568|ensembl:ENST00000469452|ensembl:ENSP00000418595|ensembl:ENST00000471745|ensembl:ENSP00000420134|ensembl:ENST00000477042|ensembl:ENSP00000419637|ensembl:ENST00000478894|ensembl:ENSP00000417777|ensembl:ENST00000482628|ensembl:ENSP00000417141|ensembl:ENST00000484955|ensembl:ENSP00000417835|ensembl:ENST00000618075|ensembl:ENSP00000484169|ensembl:ENST00000651874|ensembl:ENSP00000498363|refseq:XP_011511155.1|refseq:XP_005247537.1|ensembl:ENSG00000178053(gene)|ensembl:ENST00000355893(transcript)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR019376|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6Y8E - - - figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:czY64xaocTjgRFAtZU19jvH4MIo9606 rigid:T87kpJM/3cln1V/R+25df7n+i8Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O52302 uniprotkb:Q01151 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-2873723|ensembl:ENSP00000368450|uniprotkb:Q5THX9 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:cd83_human(display_long)|uniprotkb:CD83(gene name)|psi-mi:CD83(display_short)|uniprotkb:B-cell activation protein(gene name synonym)|uniprotkb:Cell surface protein HB15(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022510|imex:IM-25964-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) ensembl:ENSG00000112149(gene)|ensembl:ENST00000379153(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:5MIX|rcsb pdb:5MJ0|rcsb pdb:5MJ1|rcsb pdb:5MJ2|refseq:NP_001035370.1|refseq:NP_004224.1|refseq:NP_001238830.1 - - - figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:ICaEMYG0gkpGAtk5ErEZlHZRcrU9606 rigid:q3REYNBSzSCVR+ZzS6OxQk9RNP0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O52302 uniprotkb:P14209 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-748547|uniprotkb:O00518|uniprotkb:Q6ICV7|uniprotkb:A6NIW1|ensembl:ENSP00000370588 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:cd99_human(display_long)|uniprotkb:T-cell surface glycoprotein E2(gene name synonym)|uniprotkb:E2 antigen(gene name synonym)|uniprotkb:Protein MIC2(gene name synonym)|uniprotkb:12E7(gene name synonym)|uniprotkb:CD99(gene name)|psi-mi:CD99(display_short)|uniprotkb:MIC2(gene name synonym)|uniprotkb:MIC2X(gene name synonym)|uniprotkb:MIC2Y(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022514|imex:IM-25964-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_001116370.1|refseq:NP_002405.1|refseq:NP_001308296.1|refseq:NP_001308297.1|refseq:NP_001308298.1|ensembl:ENSG00000002586(gene)|ensembl:ENST00000381192(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0072683"(T cell extravasation)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|interpro:IPR022078|reactome:R-HSA-198933|reactome:R-HSA-202733 - - - figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:g0uUrvPtgp5eBwP7RXnQa0Ij6GU9606 rigid:ZgeAHVSJepYM/k3jS+UI9CJySYg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O52302 uniprotkb:Q15365 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022518|imex:IM-25964-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 rigid:YXI73AeFFVxCnyOL9usKoIDOPjQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O52302 uniprotkb:Q7Z692 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-14022522|uniprotkb:Q5XJ15|uniprotkb:Q7Z693|ensembl:ENSP00000384887 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:cea19_human(display_long)|uniprotkb:CEACAM19(gene name)|psi-mi:CEACAM19(display_short)|uniprotkb:CEAL1(gene name synonym)|uniprotkb:Carcinoembryonic antigen-like 1(gene name synonym)|uniprotkb:UNQ2973/PRO7436(orf name) psi-mi:"MI:0018"(two hybrid) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022541|imex:IM-25964-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_001121365.1|refseq:NP_064604.2|ensembl:ENSG00000186567(gene)|ensembl:ENST00000403660(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179 - - - figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:rTxW6wxwBH1I6yL1pUvLqRP8LzY9606 rigid:QOtrpw+e/zyOX7PPtxGOZ77I15Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O52302 uniprotkb:P08195 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022586|imex:IM-25964-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240 - - - figure legend:4A-B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606 rigid:TaSgkNFpMY426/PB9oRcUQdV4TI false green fluorescent protein tag:n-n flag tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O52302 uniprotkb:P08195 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022601|imex:IM-25964-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240 - - - figure legend:4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606 rigid:TaSgkNFpMY426/PB9oRcUQdV4TI false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O52302 uniprotkb:P08195 intact:EBI-14022357|ensemblbacteria:APT04785|ensemblbacteria:CTT94135|ensemblbacteria:OEI57969|ensemblbacteria:STI88413 intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122 psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:BJJ90_23640(orf name)|uniprotkb:B6R12_005237(orf name)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)|uniprotkb:E2135_19530(orf name) psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shames et al. (2010) pubmed:20374249|imex:IM-25964 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-14022610|imex:IM-25964-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000338345.1|interpro:IPR009275(SepZ)|ensemblbacteria:A9R57_21680(gene)|ensemblbacteria:APT04785(transcript)|ensemblbacteria:BJJ90_23640(gene)|ensemblbacteria:CTT94135(transcript)|ensemblbacteria:ERS085379_04436(gene)|ensemblbacteria:NCTC8622_07612(gene)|ensemblbacteria:OEI57969(transcript)|ensemblbacteria:STI88413(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140415"(effector-mediated modulation of host defenses by symbiont) refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240 - - - figure legend:4F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/04/02 2017/04/04 rogid:cu7EZCQAAnfrCeatALdw7beaSF8562 rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606 rigid:TaSgkNFpMY426/PB9oRcUQdV4TI false green fluorescent protein tag:?-?|necessary binding region:43-99 flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)