#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q24564 uniprotkb:Q24564 intact:EBI-180142|uniprotkb:Q24054|uniprotkb:Q8SWY3|ensemblmetazoa:FBpp0074523|ensemblmetazoa:FBpp0311877 intact:EBI-180142|uniprotkb:Q24054|uniprotkb:Q8SWY3|ensemblmetazoa:FBpp0074523|ensemblmetazoa:FBpp0311877 psi-mi:merh_drome(display_long)|uniprotkb:Mer(gene name)|psi-mi:Mer(display_short)|uniprotkb:EMR2(gene name synonym)|uniprotkb:CG14228(orf name)|uniprotkb:Ezrin-moesin-radixin 2(gene name synonym)|uniprotkb:Merlin(gene name synonym) psi-mi:merh_drome(display_long)|uniprotkb:Mer(gene name)|psi-mi:Mer(display_short)|uniprotkb:EMR2(gene name synonym)|uniprotkb:CG14228(orf name)|uniprotkb:Ezrin-moesin-radixin 2(gene name synonym)|uniprotkb:Merlin(gene name synonym) psi-mi:"MI:0096"(pull down) Benseñor et al. (2010) pubmed:20368450|doi:10.1073/pnas.0907389107|imex:IM-16384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15846933|imex:IM-16384-1|dip:DIP-45327E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523413.1|flybase:FBgn0086384|refseq:NP_001285458.1|dip:DIP-17087N|ensemblmetazoa:FBgn0086384(gene)|ensemblmetazoa:FBtr0074754(transcript)|ensemblmetazoa:FBtr0345992(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009798"(axis specification)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016006"(Nebenkern)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035329"(hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046669"(regulation of compound eye retinal cell programmed cell death)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0120219"(subapical part of cell)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|rcsb pdb:7EDR|reactome:R-DME-2029482|reactome:R-DME-5627123 refseq:NP_523413.1|flybase:FBgn0086384|refseq:NP_001285458.1|dip:DIP-17087N|ensemblmetazoa:FBgn0086384(gene)|ensemblmetazoa:FBtr0074754(transcript)|ensemblmetazoa:FBtr0345992(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009798"(axis specification)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016006"(Nebenkern)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035329"(hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046669"(regulation of compound eye retinal cell programmed cell death)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0120219"(subapical part of cell)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|rcsb pdb:7EDR|reactome:R-DME-2029482|reactome:R-DME-5627123 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:L3AloQnHvXayDqSyF+QhKptEjjQ7227 rogid:L3AloQnHvXayDqSyF+QhKptEjjQ7227 rigid:Hr1IX51AjbxsES6u1y8y9ikN7EQ false - green fluorescent protein tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q24564 uniprotkb:P37276 intact:EBI-180142|uniprotkb:Q24054|uniprotkb:Q8SWY3|ensemblmetazoa:FBpp0074523|ensemblmetazoa:FBpp0311877 intact:EBI-484454|uniprotkb:Q8IRA5|uniprotkb:Q961M8|uniprotkb:Q9VZ83|ensemblmetazoa:FBpp0073215 psi-mi:merh_drome(display_long)|uniprotkb:Mer(gene name)|psi-mi:Mer(display_short)|uniprotkb:EMR2(gene name synonym)|uniprotkb:CG14228(orf name)|uniprotkb:Ezrin-moesin-radixin 2(gene name synonym)|uniprotkb:Merlin(gene name synonym) psi-mi:dyhc_drome(display_long)|uniprotkb:Dhc64C(gene name)|psi-mi:Dhc64C(display_short)|uniprotkb:cDhc(gene name synonym)|uniprotkb:CG7507(orf name)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Benseñor et al. (2010) pubmed:20368450|doi:10.1073/pnas.0907389107|imex:IM-16384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15846952|imex:IM-16384-2|dip:DIP-187580E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523413.1|flybase:FBgn0086384|refseq:NP_001285458.1|dip:DIP-17087N|ensemblmetazoa:FBgn0086384(gene)|ensemblmetazoa:FBtr0074754(transcript)|ensemblmetazoa:FBtr0345992(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009798"(axis specification)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016006"(Nebenkern)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035329"(hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046669"(regulation of compound eye retinal cell programmed cell death)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0120219"(subapical part of cell)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|rcsb pdb:7EDR|reactome:R-DME-2029482|reactome:R-DME-5627123 refseq:NP_523929.2|refseq:NP_729034.2|flybase:FBgn0261797|ensemblmetazoa:FBgn0261797(gene)|ensemblmetazoa:FBtr0073359(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007279"(pole cell formation)|go:"GO:0007282"(cystoblast division)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0007349"(cellularization)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0016319"(mushroom body development)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030286"(dynein complex)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0045169"(fusome)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045478"(fusome organization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|reactome:R-DME-3371497|reactome:R-DME-6798695|reactome:R-DME-6807878|reactome:R-DME-6811436|reactome:R-DME-9646399|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0048134"(germ-line cyst formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051237"(maintenance of RNA location)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051642"(centrosome localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0098958"(retrograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904801"(positive regulation of neuron remodeling)|dip:DIP-59317N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:L3AloQnHvXayDqSyF+QhKptEjjQ7227 rogid:i1MslHIExANpuhorg5wRZk6vR3s7227 rigid:3d4DnhucKk2f42hB/Mk69x09Q/4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q24564 uniprotkb:P17210 intact:EBI-180142|uniprotkb:Q24054|uniprotkb:Q8SWY3|ensemblmetazoa:FBpp0074523|ensemblmetazoa:FBpp0311877 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:merh_drome(display_long)|uniprotkb:Mer(gene name)|psi-mi:Mer(display_short)|uniprotkb:EMR2(gene name synonym)|uniprotkb:CG14228(orf name)|uniprotkb:Ezrin-moesin-radixin 2(gene name synonym)|uniprotkb:Merlin(gene name synonym) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Benseñor et al. (2010) pubmed:20368450|doi:10.1073/pnas.0907389107|imex:IM-16384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15846952|imex:IM-16384-2|dip:DIP-187580E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523413.1|flybase:FBgn0086384|refseq:NP_001285458.1|dip:DIP-17087N|ensemblmetazoa:FBgn0086384(gene)|ensemblmetazoa:FBtr0074754(transcript)|ensemblmetazoa:FBtr0345992(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009798"(axis specification)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016006"(Nebenkern)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035329"(hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046669"(regulation of compound eye retinal cell programmed cell death)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0120219"(subapical part of cell)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|rcsb pdb:7EDR|reactome:R-DME-2029482|reactome:R-DME-5627123 refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:L3AloQnHvXayDqSyF+QhKptEjjQ7227 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rigid:3d4DnhucKk2f42hB/Mk69x09Q/4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q24564 uniprotkb:P37276 intact:EBI-180142|uniprotkb:Q24054|uniprotkb:Q8SWY3|ensemblmetazoa:FBpp0074523|ensemblmetazoa:FBpp0311877 intact:EBI-484454|uniprotkb:Q8IRA5|uniprotkb:Q961M8|uniprotkb:Q9VZ83|ensemblmetazoa:FBpp0073215 psi-mi:merh_drome(display_long)|uniprotkb:Mer(gene name)|psi-mi:Mer(display_short)|uniprotkb:EMR2(gene name synonym)|uniprotkb:CG14228(orf name)|uniprotkb:Ezrin-moesin-radixin 2(gene name synonym)|uniprotkb:Merlin(gene name synonym) psi-mi:dyhc_drome(display_long)|uniprotkb:Dhc64C(gene name)|psi-mi:Dhc64C(display_short)|uniprotkb:cDhc(gene name synonym)|uniprotkb:CG7507(orf name)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym) psi-mi:"MI:0096"(pull down) Benseñor et al. (2010) pubmed:20368450|doi:10.1073/pnas.0907389107|imex:IM-16384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15846970|imex:IM-16384-3|dip:DIP-187580E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523413.1|flybase:FBgn0086384|refseq:NP_001285458.1|dip:DIP-17087N|ensemblmetazoa:FBgn0086384(gene)|ensemblmetazoa:FBtr0074754(transcript)|ensemblmetazoa:FBtr0345992(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009798"(axis specification)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016006"(Nebenkern)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035329"(hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046669"(regulation of compound eye retinal cell programmed cell death)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0120219"(subapical part of cell)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|rcsb pdb:7EDR|reactome:R-DME-2029482|reactome:R-DME-5627123 refseq:NP_523929.2|refseq:NP_729034.2|flybase:FBgn0261797|ensemblmetazoa:FBgn0261797(gene)|ensemblmetazoa:FBtr0073359(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007279"(pole cell formation)|go:"GO:0007282"(cystoblast division)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0007349"(cellularization)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0016319"(mushroom body development)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030286"(dynein complex)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0045169"(fusome)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045478"(fusome organization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|reactome:R-DME-3371497|reactome:R-DME-6798695|reactome:R-DME-6807878|reactome:R-DME-6811436|reactome:R-DME-9646399|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0048134"(germ-line cyst formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051237"(maintenance of RNA location)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051642"(centrosome localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0098958"(retrograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904801"(positive regulation of neuron remodeling)|dip:DIP-59317N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:L3AloQnHvXayDqSyF+QhKptEjjQ7227 rogid:i1MslHIExANpuhorg5wRZk6vR3s7227 rigid:3d4DnhucKk2f42hB/Mk69x09Q/4 false green fluorescent protein tag:c-c|mutation disrupting interaction:70-70 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q24564 uniprotkb:P17210 intact:EBI-180142|uniprotkb:Q24054|uniprotkb:Q8SWY3|ensemblmetazoa:FBpp0074523|ensemblmetazoa:FBpp0311877 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:merh_drome(display_long)|uniprotkb:Mer(gene name)|psi-mi:Mer(display_short)|uniprotkb:EMR2(gene name synonym)|uniprotkb:CG14228(orf name)|uniprotkb:Ezrin-moesin-radixin 2(gene name synonym)|uniprotkb:Merlin(gene name synonym) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0096"(pull down) Benseñor et al. (2010) pubmed:20368450|doi:10.1073/pnas.0907389107|imex:IM-16384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15846970|imex:IM-16384-3|dip:DIP-187580E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523413.1|flybase:FBgn0086384|refseq:NP_001285458.1|dip:DIP-17087N|ensemblmetazoa:FBgn0086384(gene)|ensemblmetazoa:FBtr0074754(transcript)|ensemblmetazoa:FBtr0345992(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009798"(axis specification)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016006"(Nebenkern)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035329"(hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046669"(regulation of compound eye retinal cell programmed cell death)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0120219"(subapical part of cell)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|rcsb pdb:7EDR|reactome:R-DME-2029482|reactome:R-DME-5627123 refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:L3AloQnHvXayDqSyF+QhKptEjjQ7227 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rigid:3d4DnhucKk2f42hB/Mk69x09Q/4 false green fluorescent protein tag:c-c|mutation disrupting interaction:70-70 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q24564 uniprotkb:P37276 intact:EBI-180142|uniprotkb:Q24054|uniprotkb:Q8SWY3|ensemblmetazoa:FBpp0074523|ensemblmetazoa:FBpp0311877 intact:EBI-484454|uniprotkb:Q8IRA5|uniprotkb:Q961M8|uniprotkb:Q9VZ83|ensemblmetazoa:FBpp0073215 psi-mi:merh_drome(display_long)|uniprotkb:Mer(gene name)|psi-mi:Mer(display_short)|uniprotkb:EMR2(gene name synonym)|uniprotkb:CG14228(orf name)|uniprotkb:Ezrin-moesin-radixin 2(gene name synonym)|uniprotkb:Merlin(gene name synonym) psi-mi:dyhc_drome(display_long)|uniprotkb:Dhc64C(gene name)|psi-mi:Dhc64C(display_short)|uniprotkb:cDhc(gene name synonym)|uniprotkb:CG7507(orf name)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Benseñor et al. (2010) pubmed:20368450|doi:10.1073/pnas.0907389107|imex:IM-16384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15846993|imex:IM-16384-4|dip:DIP-187580E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523413.1|flybase:FBgn0086384|refseq:NP_001285458.1|dip:DIP-17087N|ensemblmetazoa:FBgn0086384(gene)|ensemblmetazoa:FBtr0074754(transcript)|ensemblmetazoa:FBtr0345992(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009798"(axis specification)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016006"(Nebenkern)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035329"(hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046669"(regulation of compound eye retinal cell programmed cell death)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0120219"(subapical part of cell)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|rcsb pdb:7EDR|reactome:R-DME-2029482|reactome:R-DME-5627123 refseq:NP_523929.2|refseq:NP_729034.2|flybase:FBgn0261797|ensemblmetazoa:FBgn0261797(gene)|ensemblmetazoa:FBtr0073359(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007279"(pole cell formation)|go:"GO:0007282"(cystoblast division)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0007349"(cellularization)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0016319"(mushroom body development)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030286"(dynein complex)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0045169"(fusome)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045478"(fusome organization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|reactome:R-DME-3371497|reactome:R-DME-6798695|reactome:R-DME-6807878|reactome:R-DME-6811436|reactome:R-DME-9646399|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0048134"(germ-line cyst formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051237"(maintenance of RNA location)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051642"(centrosome localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0098958"(retrograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904801"(positive regulation of neuron remodeling)|dip:DIP-59317N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:L3AloQnHvXayDqSyF+QhKptEjjQ7227 rogid:i1MslHIExANpuhorg5wRZk6vR3s7227 rigid:3d4DnhucKk2f42hB/Mk69x09Q/4 false green fluorescent protein tag:c-c|mutation disrupting interaction:616-616 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q24564 uniprotkb:P17210 intact:EBI-180142|uniprotkb:Q24054|uniprotkb:Q8SWY3|ensemblmetazoa:FBpp0074523|ensemblmetazoa:FBpp0311877 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:merh_drome(display_long)|uniprotkb:Mer(gene name)|psi-mi:Mer(display_short)|uniprotkb:EMR2(gene name synonym)|uniprotkb:CG14228(orf name)|uniprotkb:Ezrin-moesin-radixin 2(gene name synonym)|uniprotkb:Merlin(gene name synonym) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Benseñor et al. (2010) pubmed:20368450|doi:10.1073/pnas.0907389107|imex:IM-16384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15846993|imex:IM-16384-4|dip:DIP-187580E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523413.1|flybase:FBgn0086384|refseq:NP_001285458.1|dip:DIP-17087N|ensemblmetazoa:FBgn0086384(gene)|ensemblmetazoa:FBtr0074754(transcript)|ensemblmetazoa:FBtr0345992(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009798"(axis specification)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016006"(Nebenkern)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035329"(hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046669"(regulation of compound eye retinal cell programmed cell death)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0120219"(subapical part of cell)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|rcsb pdb:7EDR|reactome:R-DME-2029482|reactome:R-DME-5627123 refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:L3AloQnHvXayDqSyF+QhKptEjjQ7227 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rigid:3d4DnhucKk2f42hB/Mk69x09Q/4 false green fluorescent protein tag:c-c|mutation disrupting interaction:616-616 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)