#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P03372-1	uniprotkb:Q9CQ39	intact:EBI-15606245|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000387500|ensembl:ENSP00000405330	intact:EBI-6260960|ensembl:ENSMUSP00000032429|ensembl:ENSMUSP00000145512|uniprotkb:Q921I5	psi-mi:p03372-1(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)|uniprotkb:ER66(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:hER-alpha66(isoform synonym)	psi-mi:med21_mouse(display_long)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:Srb7(gene name synonym)|uniprotkb:Surb7(gene name synonym)|uniprotkb:Med21(gene name)|psi-mi:Med21(display_short)	psi-mi:"MI:0096"(pull down)	Jiang et al. (2010)	pubmed:20351249|doi:10.1073/pnas.1001814107|imex:IM-17437	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844930|imex:IM-17437-1|dip:DIP-188347E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78473(isoform-parent)|ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)	ensembl:ENSMUSG00000030291(gene)|ensembl:ENSMUST00000032429(transcript)|ensembl:ENSMUST00000204040(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:6W1S|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:NP_079591.1|dip:DIP-59522N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:4a1HoRbOTd2Nm/gDGbidH5rrMbg10090	rigid:31gsEt/6XBNk0Z96+hf1nrWyjpw	false	binding-associated region:302-595|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03372-1	uniprotkb:Q8VCD5	intact:EBI-15606245|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000387500|ensembl:ENSP00000405330	intact:EBI-5744951|uniprotkb:Q8BYS6|uniprotkb:Q99KQ1|ensembl:ENSMUSP00000034411	psi-mi:p03372-1(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)|uniprotkb:ER66(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:hER-alpha66(isoform synonym)	psi-mi:med17_mouse(display_long)|uniprotkb:Med17(gene name)|psi-mi:Med17(display_short)|uniprotkb:Crsp6(gene name synonym)|uniprotkb:Trap80(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jiang et al. (2010)	pubmed:20351249|doi:10.1073/pnas.1001814107|imex:IM-17437	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844930|imex:IM-17437-1|dip:DIP-188347E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78473(isoform-parent)|ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)	refseq:NP_659182.1|ensembl:ENSMUSG00000031935(gene)|ensembl:ENSMUST00000034411(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|rcsb pdb:6W1S|reactome:R-MMU-212436|dip:DIP-48407N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:RphTDePi36YqZFcRmkcobUnPd7I10090	rigid:31gsEt/6XBNk0Z96+hf1nrWyjpw	false	binding-associated region:302-595|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03372-1	uniprotkb:Q6PGF3	intact:EBI-15606245|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000387500|ensembl:ENSP00000405330	intact:EBI-6260816|uniprotkb:E9QM81	psi-mi:p03372-1(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)|uniprotkb:ER66(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:hER-alpha66(isoform synonym)	psi-mi:med16_mouse(display_long)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thrap5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)	psi-mi:"MI:0096"(pull down)	Jiang et al. (2010)	pubmed:20351249|doi:10.1073/pnas.1001814107|imex:IM-17437	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844930|imex:IM-17437-1|dip:DIP-188347E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78473(isoform-parent)|ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)	go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:Q6PGF3|dip:DIP-48408N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:7RYpXMMTPBtLxPGifdlY+MdwlEM10090	rigid:31gsEt/6XBNk0Z96+hf1nrWyjpw	false	binding-associated region:302-595|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03372-1	uniprotkb:A2AGH6	intact:EBI-15606245|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000387500|ensembl:ENSP00000405330	intact:EBI-5744969|uniprotkb:A2AGH7|uniprotkb:O88542|uniprotkb:Q571H3|uniprotkb:Q6PGB4|uniprotkb:Q6PGD8|ensembl:ENSMUSP00000085260	psi-mi:p03372-1(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)|uniprotkb:ER66(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:hER-alpha66(isoform synonym)	psi-mi:med12_mouse(display_long)|uniprotkb:Med12(gene name)|psi-mi:Med12(display_short)|uniprotkb:Kiaa0192(gene name synonym)|uniprotkb:Mopa(gene name synonym)|uniprotkb:Tnrc11(gene name synonym)|uniprotkb:Trap230(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jiang et al. (2010)	pubmed:20351249|doi:10.1073/pnas.1001814107|imex:IM-17437	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844930|imex:IM-17437-1|dip:DIP-188347E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78473(isoform-parent)|ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)	refseq:NP_067496.2|go:"GO:0048568"(embryonic organ development)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:1990403"(embryonic brain development)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:A2AGH6|reactome:R-MMU-212436|ensembl:ENSMUSG00000079487(gene)|ensembl:ENSMUST00000087948(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001756"(somitogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021915"(neural tube development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|dip:DIP-59233N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:9l10cOqNn+PIwL7gQq/WsgiZnLE10090	rigid:31gsEt/6XBNk0Z96+hf1nrWyjpw	false	binding-associated region:302-595|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:G8HBG2	uniprotkb:Q9CQ39	intact:EBI-15844956	intact:EBI-6260960|ensembl:ENSMUSP00000032429|ensembl:ENSMUSP00000145512|uniprotkb:Q921I5	psi-mi:g8hbg2_hhv11(display_long)|uniprotkb:UL48(gene name)|psi-mi:UL48(display_short)|uniprotkb:Alpha-TIF(gene name synonym)	psi-mi:med21_mouse(display_long)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:Srb7(gene name synonym)|uniprotkb:Surb7(gene name synonym)|uniprotkb:Med21(gene name)|psi-mi:Med21(display_short)	psi-mi:"MI:0096"(pull down)	Jiang et al. (2010)	pubmed:20351249|doi:10.1073/pnas.1001814107|imex:IM-17437	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844966|imex:IM-17437-2|dip:DIP-188348E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|interpro:IPR003174("Alpha trans-inducing protein (Alpha-TIF)")|interpro:IPR021051|refseq:YP_009137123.1|interpro:IPR036538	ensembl:ENSMUSG00000030291(gene)|ensembl:ENSMUST00000032429(transcript)|ensembl:ENSMUST00000204040(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:6W1S|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:NP_079591.1|dip:DIP-59522N	psi-mi:"MI:0465"(dip)	crc64:8DDDEDEDB2A699D3	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:8rAT+y7LSTotMP4XcD+eSyMpff010299	rogid:4a1HoRbOTd2Nm/gDGbidH5rrMbg10090	rigid:4Gmx+HxzW091yF5KJxzmN5m/aBc	false	binding-associated region:412-490|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:G8HBG2	uniprotkb:Q8VCD5	intact:EBI-15844956	intact:EBI-5744951|uniprotkb:Q8BYS6|uniprotkb:Q99KQ1|ensembl:ENSMUSP00000034411	psi-mi:g8hbg2_hhv11(display_long)|uniprotkb:UL48(gene name)|psi-mi:UL48(display_short)|uniprotkb:Alpha-TIF(gene name synonym)	psi-mi:med17_mouse(display_long)|uniprotkb:Med17(gene name)|psi-mi:Med17(display_short)|uniprotkb:Crsp6(gene name synonym)|uniprotkb:Trap80(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jiang et al. (2010)	pubmed:20351249|doi:10.1073/pnas.1001814107|imex:IM-17437	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844966|imex:IM-17437-2|dip:DIP-188348E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|interpro:IPR003174("Alpha trans-inducing protein (Alpha-TIF)")|interpro:IPR021051|refseq:YP_009137123.1|interpro:IPR036538	refseq:NP_659182.1|ensembl:ENSMUSG00000031935(gene)|ensembl:ENSMUST00000034411(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|rcsb pdb:6W1S|reactome:R-MMU-212436|dip:DIP-48407N	psi-mi:"MI:0465"(dip)	crc64:8DDDEDEDB2A699D3	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:8rAT+y7LSTotMP4XcD+eSyMpff010299	rogid:RphTDePi36YqZFcRmkcobUnPd7I10090	rigid:4Gmx+HxzW091yF5KJxzmN5m/aBc	false	binding-associated region:412-490|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:G8HBG2	uniprotkb:Q6PGF3	intact:EBI-15844956	intact:EBI-6260816|uniprotkb:E9QM81	psi-mi:g8hbg2_hhv11(display_long)|uniprotkb:UL48(gene name)|psi-mi:UL48(display_short)|uniprotkb:Alpha-TIF(gene name synonym)	psi-mi:med16_mouse(display_long)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thrap5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)	psi-mi:"MI:0096"(pull down)	Jiang et al. (2010)	pubmed:20351249|doi:10.1073/pnas.1001814107|imex:IM-17437	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844966|imex:IM-17437-2|dip:DIP-188348E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|interpro:IPR003174("Alpha trans-inducing protein (Alpha-TIF)")|interpro:IPR021051|refseq:YP_009137123.1|interpro:IPR036538	go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:Q6PGF3|dip:DIP-48408N	psi-mi:"MI:0465"(dip)	crc64:8DDDEDEDB2A699D3	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:8rAT+y7LSTotMP4XcD+eSyMpff010299	rogid:7RYpXMMTPBtLxPGifdlY+MdwlEM10090	rigid:4Gmx+HxzW091yF5KJxzmN5m/aBc	false	binding-associated region:412-490|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:G8HBG2	uniprotkb:A2AGH6	intact:EBI-15844956	intact:EBI-5744969|uniprotkb:A2AGH7|uniprotkb:O88542|uniprotkb:Q571H3|uniprotkb:Q6PGB4|uniprotkb:Q6PGD8|ensembl:ENSMUSP00000085260	psi-mi:g8hbg2_hhv11(display_long)|uniprotkb:UL48(gene name)|psi-mi:UL48(display_short)|uniprotkb:Alpha-TIF(gene name synonym)	psi-mi:med12_mouse(display_long)|uniprotkb:Med12(gene name)|psi-mi:Med12(display_short)|uniprotkb:Kiaa0192(gene name synonym)|uniprotkb:Mopa(gene name synonym)|uniprotkb:Tnrc11(gene name synonym)|uniprotkb:Trap230(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jiang et al. (2010)	pubmed:20351249|doi:10.1073/pnas.1001814107|imex:IM-17437	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844966|imex:IM-17437-2|dip:DIP-188348E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|interpro:IPR003174("Alpha trans-inducing protein (Alpha-TIF)")|interpro:IPR021051|refseq:YP_009137123.1|interpro:IPR036538	refseq:NP_067496.2|go:"GO:0048568"(embryonic organ development)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:1990403"(embryonic brain development)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:A2AGH6|reactome:R-MMU-212436|ensembl:ENSMUSG00000079487(gene)|ensembl:ENSMUST00000087948(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001756"(somitogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021915"(neural tube development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|dip:DIP-59233N	psi-mi:"MI:0465"(dip)	crc64:8DDDEDEDB2A699D3	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:8rAT+y7LSTotMP4XcD+eSyMpff010299	rogid:9l10cOqNn+PIwL7gQq/WsgiZnLE10090	rigid:4Gmx+HxzW091yF5KJxzmN5m/aBc	false	binding-associated region:412-490|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)