#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Z3B6	uniprotkb:Q9Z3B6	intact:EBI-15844837	intact:EBI-15844837	psi-mi:q9z3b6_neime(display_long)|uniprotkb:porB(gene name)|psi-mi:porB(display_short)	psi-mi:q9z3b6_neime(display_long)|uniprotkb:porB(gene name)|psi-mi:porB(display_short)	psi-mi:"MI:0071"(molecular sieving)	Tanabe et al. (2010)	pubmed:20351243|doi:10.1073/pnas.0912115107|imex:IM-15242	taxid:487(neime)|taxid:487(Neisseria meningitidis)	taxid:487(neime)|taxid:487(Neisseria meningitidis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844851|imex:IM-15242-1|dip:DIP-185750E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046930"(pore complex)|interpro:IPR001702(Porin, Gram-negative type)|interpro:IPR002299(Porin, Neisseria sp. type)|interpro:IPR013793(Porin, general diffusion Gram-negative, conserved site)|interpro:IPR023614|interpro:IPR033900|dip:DIP-58637N	go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046930"(pore complex)|interpro:IPR001702(Porin, Gram-negative type)|interpro:IPR002299(Porin, Neisseria sp. type)|interpro:IPR013793(Porin, general diffusion Gram-negative, conserved site)|interpro:IPR023614|interpro:IPR033900|dip:DIP-58637N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:e1Fjg8foTCHI1X2c0DosWCK/CJE487	rogid:e1Fjg8foTCHI1X2c0DosWCK/CJE487	rigid:csB3wqSZWagy12O45S4GZWMnZVU	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Z3B6	uniprotkb:Q9Z3B6	intact:EBI-15844837	intact:EBI-15844837	psi-mi:q9z3b6_neime(display_long)|uniprotkb:porB(gene name)|psi-mi:porB(display_short)	psi-mi:q9z3b6_neime(display_long)|uniprotkb:porB(gene name)|psi-mi:porB(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Tanabe et al. (2010)	pubmed:20351243|doi:10.1073/pnas.0912115107|imex:IM-15242	taxid:487(neime)|taxid:487(Neisseria meningitidis)	taxid:487(neime)|taxid:487(Neisseria meningitidis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844871|imex:IM-15242-2|dip:DIP-185750E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046930"(pore complex)|interpro:IPR001702(Porin, Gram-negative type)|interpro:IPR002299(Porin, Neisseria sp. type)|interpro:IPR013793(Porin, general diffusion Gram-negative, conserved site)|interpro:IPR023614|interpro:IPR033900|dip:DIP-58637N	go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046930"(pore complex)|interpro:IPR001702(Porin, Gram-negative type)|interpro:IPR002299(Porin, Neisseria sp. type)|interpro:IPR013793(Porin, general diffusion Gram-negative, conserved site)|interpro:IPR023614|interpro:IPR033900|dip:DIP-58637N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:e1Fjg8foTCHI1X2c0DosWCK/CJE487	rogid:e1Fjg8foTCHI1X2c0DosWCK/CJE487	rigid:csB3wqSZWagy12O45S4GZWMnZVU	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60603	uniprotkb:Q9Z3B6	intact:EBI-973722|ensembl:ENSP00000260010|ensembl:ENSP00000494425|ensembl:ENSP00000495339|uniprotkb:O15454|uniprotkb:Q8NI00|uniprotkb:B3Y612|uniprotkb:D1CS45|uniprotkb:D1CS48|uniprotkb:D1CS49	intact:EBI-15844837	psi-mi:tlr2_human(display_long)|uniprotkb:Toll/interleukin-1 receptor-like protein 4(gene name synonym)|uniprotkb:TLR2(gene name)|psi-mi:TLR2(display_short)|uniprotkb:TIL4(gene name synonym)	psi-mi:q9z3b6_neime(display_long)|uniprotkb:porB(gene name)|psi-mi:porB(display_short)	psi-mi:"MI:0071"(molecular sieving)	Tanabe et al. (2010)	pubmed:20351243|doi:10.1073/pnas.0912115107|imex:IM-15242	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:487(neime)|taxid:487(Neisseria meningitidis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844887|imex:IM-15242-3|dip:DIP-185751E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137462(gene)|ensembl:ENST00000260010(transcript)|ensembl:ENST00000642580(transcript)|ensembl:ENST00000642700(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001775"(cell activation)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007612"(learning)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0014005"(microglia development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032289"(central nervous system myelin formation)|go:"GO:0032570"(response to progesterone)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0034123"(positive regulation of toll-like receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035354"(Toll-like receptor 1-Toll-like receptor 2 protein complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042495"(detection of triacyl bacterial lipopeptide)|go:"GO:0042496"(detection of diacyl bacterial lipopeptide)|go:"GO:0042497"(triacyl lipopeptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0042995"(cell projection)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046209"(nitric oxide metabolic process)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071221"(cellular response to bacterial lipopeptide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071727"(cellular response to triacyl bacterial lipopeptide)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903974"(positive regulation of cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR027185|interpro:IPR032675|interpro:IPR035897|mint:O60603|rcsb pdb:1FYW|rcsb pdb:1FYX|rcsb pdb:1O77|rcsb pdb:2Z7X|rcsb pdb:2Z80|rcsb pdb:6NIG|reactome:R-HSA-1461957|reactome:R-HSA-166058|reactome:R-HSA-168179|reactome:R-HSA-168188|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-9637628|reactome:R-HSA-1236974|refseq:NP_003255.2|refseq:XP_011530517.1|refseq:XP_011530518.1|refseq:XP_016864062.1|refseq:XP_016864063.1|refseq:XP_016864064.1|refseq:XP_016864065.1|refseq:NP_001305716.1|refseq:NP_001305718.1|refseq:NP_001305719.1|refseq:NP_001305720.1|refseq:NP_001305722.1|refseq:NP_001305725.1|refseq:NP_001305724.1|dip:DIP-35138N	go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046930"(pore complex)|interpro:IPR001702(Porin, Gram-negative type)|interpro:IPR002299(Porin, Neisseria sp. type)|interpro:IPR013793(Porin, general diffusion Gram-negative, conserved site)|interpro:IPR023614|interpro:IPR033900|dip:DIP-58637N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:6xdppMwVYR7qWpDocSsqwvocdU89606	rogid:e1Fjg8foTCHI1X2c0DosWCK/CJE487	rigid:KYLHtdAxGje08WnLT/2NELSoLyk	false	binding-associated region:19-588	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Z3B6	uniprotkb:Q9Z3B6	intact:EBI-15844837	intact:EBI-15844837	psi-mi:q9z3b6_neime(display_long)|uniprotkb:porB(gene name)|psi-mi:porB(display_short)	psi-mi:q9z3b6_neime(display_long)|uniprotkb:porB(gene name)|psi-mi:porB(display_short)	psi-mi:"MI:0067"(light scattering)	Tanabe et al. (2010)	pubmed:20351243|doi:10.1073/pnas.0912115107|imex:IM-15242	taxid:487(neime)|taxid:487(Neisseria meningitidis)	taxid:487(neime)|taxid:487(Neisseria meningitidis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15844906|imex:IM-15242-4|dip:DIP-185750E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046930"(pore complex)|interpro:IPR001702(Porin, Gram-negative type)|interpro:IPR002299(Porin, Neisseria sp. type)|interpro:IPR013793(Porin, general diffusion Gram-negative, conserved site)|interpro:IPR023614|interpro:IPR033900|dip:DIP-58637N	go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046930"(pore complex)|interpro:IPR001702(Porin, Gram-negative type)|interpro:IPR002299(Porin, Neisseria sp. type)|interpro:IPR013793(Porin, general diffusion Gram-negative, conserved site)|interpro:IPR023614|interpro:IPR033900|dip:DIP-58637N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:e1Fjg8foTCHI1X2c0DosWCK/CJE487	rogid:e1Fjg8foTCHI1X2c0DosWCK/CJE487	rigid:csB3wqSZWagy12O45S4GZWMnZVU	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)