#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q14627	uniprotkb:P35225	intact:EBI-4320063|uniprotkb:A8K7E2|uniprotkb:O00667|ensembl:ENSP00000243213|ensembl:ENSP00000361004	intact:EBI-1647828|uniprotkb:O43644|uniprotkb:Q4VB52|uniprotkb:Q9UDC7|ensembl:ENSP00000304915	psi-mi:i13r2_human(display_long)|uniprotkb:IL13RA2(gene name)|psi-mi:IL13RA2(display_short)|uniprotkb:IL13R(gene name synonym)|uniprotkb:Interleukin-13-binding protein(gene name synonym)	psi-mi:il13_human(display_long)|uniprotkb:IL13(gene name)|psi-mi:IL13(display_short)|uniprotkb:NC30(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Lupardus et al. (2010)	pubmed:20223216|doi:10.1016/j.str.2010.01.003|imex:IM-15909	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15841898|imex:IM-15909-1|dip:DIP-4684E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000631.1|ensembl:ENSG00000123496(gene)|ensembl:ENST00000243213(transcript)|ensembl:ENST00000371936(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043305"(negative regulation of mast cell degranulation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:3LB6|reactome:R-HSA-6785807|dip:DIP-3340N	refseq:NP_002179.2|dip:DIP-3224N|ensembl:ENSG00000169194(gene)|ensembl:ENST00000304506(transcript)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005144"(interleukin-13 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010155"(regulation of proton transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032723"(positive regulation of connective tissue growth factor production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0035094"(response to nicotine)|go:"GO:0042116"(macrophage activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0045471"(response to ethanol)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901247"(negative regulation of lung ciliated cell differentiation)|go:"GO:1901251"(positive regulation of lung goblet cell differentiation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:2000231"(positive regulation of pancreatic stellate cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR001325(Interleukin-4/interleukin-13)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR018096|interpro:IPR020470|rcsb pdb:1GA3|rcsb pdb:1IJZ|rcsb pdb:1IK0|rcsb pdb:1J9U|rcsb pdb:3BPO|rcsb pdb:3G6D|rcsb pdb:3ITR|rcsb pdb:3ITS|rcsb pdb:3L5W|rcsb pdb:3L5X|rcsb pdb:3LB6|rcsb pdb:4I77|rcsb pdb:4PS4|rcsb pdb:5E4E|rcsb pdb:5L6Y|reactome:R-HSA-6785807|reactome:R-HSA-9012546	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:LItbTlLuFXGhjC4PVCIW9aeBRZk9606	rogid:NORPxfYHTfYxQaFWP3FFlC76bWE9606	rigid:wPMlTdJsawR38ioaYml0+k5Ti7c	false	binding-associated region:29-331	binding-associated region:21-132	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14627	uniprotkb:P35225	intact:EBI-4320063|uniprotkb:A8K7E2|uniprotkb:O00667|ensembl:ENSP00000243213|ensembl:ENSP00000361004	intact:EBI-1647828|uniprotkb:O43644|uniprotkb:Q4VB52|uniprotkb:Q9UDC7|ensembl:ENSP00000304915	psi-mi:i13r2_human(display_long)|uniprotkb:IL13RA2(gene name)|psi-mi:IL13RA2(display_short)|uniprotkb:IL13R(gene name synonym)|uniprotkb:Interleukin-13-binding protein(gene name synonym)	psi-mi:il13_human(display_long)|uniprotkb:IL13(gene name)|psi-mi:IL13(display_short)|uniprotkb:NC30(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Lupardus et al. (2010)	pubmed:20223216|doi:10.1016/j.str.2010.01.003|imex:IM-15909	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15841919|imex:IM-15909-2|dip:DIP-4684E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000631.1|ensembl:ENSG00000123496(gene)|ensembl:ENST00000243213(transcript)|ensembl:ENST00000371936(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043305"(negative regulation of mast cell degranulation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:3LB6|reactome:R-HSA-6785807|dip:DIP-3340N	refseq:NP_002179.2|dip:DIP-3224N|ensembl:ENSG00000169194(gene)|ensembl:ENST00000304506(transcript)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005144"(interleukin-13 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010155"(regulation of proton transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032723"(positive regulation of connective tissue growth factor production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0035094"(response to nicotine)|go:"GO:0042116"(macrophage activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0045471"(response to ethanol)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901247"(negative regulation of lung ciliated cell differentiation)|go:"GO:1901251"(positive regulation of lung goblet cell differentiation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:2000231"(positive regulation of pancreatic stellate cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR001325(Interleukin-4/interleukin-13)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR018096|interpro:IPR020470|rcsb pdb:1GA3|rcsb pdb:1IJZ|rcsb pdb:1IK0|rcsb pdb:1J9U|rcsb pdb:3BPO|rcsb pdb:3G6D|rcsb pdb:3ITR|rcsb pdb:3ITS|rcsb pdb:3L5W|rcsb pdb:3L5X|rcsb pdb:3LB6|rcsb pdb:4I77|rcsb pdb:4PS4|rcsb pdb:5E4E|rcsb pdb:5L6Y|reactome:R-HSA-6785807|reactome:R-HSA-9012546	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/06	2017/08/10	rogid:LItbTlLuFXGhjC4PVCIW9aeBRZk9606	rogid:NORPxfYHTfYxQaFWP3FFlC76bWE9606	rigid:wPMlTdJsawR38ioaYml0+k5Ti7c	false	binding-associated region:29-331	binding-associated region:21-132	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P78552	uniprotkb:P35225	intact:EBI-1391535|uniprotkb:O95646|uniprotkb:Q99656|intact:EBI-3918927|uniprotkb:Q5JSL4|uniprotkb:Q9UDY5|ensembl:ENSP00000360730	intact:EBI-1647828|uniprotkb:O43644|uniprotkb:Q4VB52|uniprotkb:Q9UDC7|ensembl:ENSP00000304915	psi-mi:i13r1_human(display_long)|uniprotkb:Cancer/testis antigen 19(gene name synonym)|uniprotkb:IL13RA1(gene name)|psi-mi:IL13RA1(display_short)|uniprotkb:IL13R(gene name synonym)|uniprotkb:IL13RA(gene name synonym)	psi-mi:il13_human(display_long)|uniprotkb:IL13(gene name)|psi-mi:IL13(display_short)|uniprotkb:NC30(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Lupardus et al. (2010)	pubmed:20223216|doi:10.1016/j.str.2010.01.003|imex:IM-15909	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15841940|imex:IM-15909-3|dip:DIP-4497E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001551.1|dip:DIP-3225N|ensembl:ENSG00000131724(gene)|interpro:IPR036116|interpro:IPR040566|rcsb pdb:3BPN|ensembl:ENST00000371666(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005898"(interleukin-13 receptor complex)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0043235"(receptor complex)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|rcsb pdb:3BPO|rcsb pdb:4HWB|rcsb pdb:5E4E|reactome:R-HSA-6785807	refseq:NP_002179.2|dip:DIP-3224N|ensembl:ENSG00000169194(gene)|ensembl:ENST00000304506(transcript)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005144"(interleukin-13 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010155"(regulation of proton transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032723"(positive regulation of connective tissue growth factor production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0035094"(response to nicotine)|go:"GO:0042116"(macrophage activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0045471"(response to ethanol)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901247"(negative regulation of lung ciliated cell differentiation)|go:"GO:1901251"(positive regulation of lung goblet cell differentiation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:2000231"(positive regulation of pancreatic stellate cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR001325(Interleukin-4/interleukin-13)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR018096|interpro:IPR020470|rcsb pdb:1GA3|rcsb pdb:1IJZ|rcsb pdb:1IK0|rcsb pdb:1J9U|rcsb pdb:3BPO|rcsb pdb:3G6D|rcsb pdb:3ITR|rcsb pdb:3ITS|rcsb pdb:3L5W|rcsb pdb:3L5X|rcsb pdb:3LB6|rcsb pdb:4I77|rcsb pdb:4PS4|rcsb pdb:5E4E|rcsb pdb:5L6Y|reactome:R-HSA-6785807|reactome:R-HSA-9012546	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:EufIBLLPq2hkBrfc1evg9tTfp1o9606	rogid:NORPxfYHTfYxQaFWP3FFlC76bWE9606	rigid:Z1zIbPxztQp3LG7UOVwxlKhUFMk	false	-	binding-associated region:21-132	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14627	uniprotkb:P35225	intact:EBI-4320063|uniprotkb:A8K7E2|uniprotkb:O00667|ensembl:ENSP00000243213|ensembl:ENSP00000361004	intact:EBI-1647828|uniprotkb:O43644|uniprotkb:Q4VB52|uniprotkb:Q9UDC7|ensembl:ENSP00000304915	psi-mi:i13r2_human(display_long)|uniprotkb:IL13RA2(gene name)|psi-mi:IL13RA2(display_short)|uniprotkb:IL13R(gene name synonym)|uniprotkb:Interleukin-13-binding protein(gene name synonym)	psi-mi:il13_human(display_long)|uniprotkb:IL13(gene name)|psi-mi:IL13(display_short)|uniprotkb:NC30(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Lupardus et al. (2010)	pubmed:20223216|doi:10.1016/j.str.2010.01.003|imex:IM-15909	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15841959|imex:IM-15909-4|dip:DIP-4684E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000631.1|ensembl:ENSG00000123496(gene)|ensembl:ENST00000243213(transcript)|ensembl:ENST00000371936(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043305"(negative regulation of mast cell degranulation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:3LB6|reactome:R-HSA-6785807|dip:DIP-3340N	refseq:NP_002179.2|dip:DIP-3224N|ensembl:ENSG00000169194(gene)|ensembl:ENST00000304506(transcript)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005144"(interleukin-13 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010155"(regulation of proton transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032723"(positive regulation of connective tissue growth factor production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0035094"(response to nicotine)|go:"GO:0042116"(macrophage activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0045471"(response to ethanol)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901247"(negative regulation of lung ciliated cell differentiation)|go:"GO:1901251"(positive regulation of lung goblet cell differentiation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:2000231"(positive regulation of pancreatic stellate cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR001325(Interleukin-4/interleukin-13)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR018096|interpro:IPR020470|rcsb pdb:1GA3|rcsb pdb:1IJZ|rcsb pdb:1IK0|rcsb pdb:1J9U|rcsb pdb:3BPO|rcsb pdb:3G6D|rcsb pdb:3ITR|rcsb pdb:3ITS|rcsb pdb:3L5W|rcsb pdb:3L5X|rcsb pdb:3LB6|rcsb pdb:4I77|rcsb pdb:4PS4|rcsb pdb:5E4E|rcsb pdb:5L6Y|reactome:R-HSA-6785807|reactome:R-HSA-9012546	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:LItbTlLuFXGhjC4PVCIW9aeBRZk9606	rogid:NORPxfYHTfYxQaFWP3FFlC76bWE9606	rigid:wPMlTdJsawR38ioaYml0+k5Ti7c	false	binding-associated region:29-331	mutation decreasing interaction:137-137|mutation decreasing interaction:140-140|binding-associated region:21-132|mutation decreasing interaction:47-47|mutation decreasing interaction:138-138	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14627	uniprotkb:P35225	intact:EBI-4320063|uniprotkb:A8K7E2|uniprotkb:O00667|ensembl:ENSP00000243213|ensembl:ENSP00000361004	intact:EBI-1647828|uniprotkb:O43644|uniprotkb:Q4VB52|uniprotkb:Q9UDC7|ensembl:ENSP00000304915	psi-mi:i13r2_human(display_long)|uniprotkb:IL13RA2(gene name)|psi-mi:IL13RA2(display_short)|uniprotkb:IL13R(gene name synonym)|uniprotkb:Interleukin-13-binding protein(gene name synonym)	psi-mi:il13_human(display_long)|uniprotkb:IL13(gene name)|psi-mi:IL13(display_short)|uniprotkb:NC30(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Lupardus et al. (2010)	pubmed:20223216|doi:10.1016/j.str.2010.01.003|imex:IM-15909	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15841993|imex:IM-15909-5|dip:DIP-4684E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000631.1|ensembl:ENSG00000123496(gene)|ensembl:ENST00000243213(transcript)|ensembl:ENST00000371936(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043305"(negative regulation of mast cell degranulation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:3LB6|reactome:R-HSA-6785807|dip:DIP-3340N	refseq:NP_002179.2|dip:DIP-3224N|ensembl:ENSG00000169194(gene)|ensembl:ENST00000304506(transcript)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005144"(interleukin-13 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010155"(regulation of proton transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032723"(positive regulation of connective tissue growth factor production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0035094"(response to nicotine)|go:"GO:0042116"(macrophage activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0045471"(response to ethanol)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901247"(negative regulation of lung ciliated cell differentiation)|go:"GO:1901251"(positive regulation of lung goblet cell differentiation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:2000231"(positive regulation of pancreatic stellate cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR001325(Interleukin-4/interleukin-13)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR018096|interpro:IPR020470|rcsb pdb:1GA3|rcsb pdb:1IJZ|rcsb pdb:1IK0|rcsb pdb:1J9U|rcsb pdb:3BPO|rcsb pdb:3G6D|rcsb pdb:3ITR|rcsb pdb:3ITS|rcsb pdb:3L5W|rcsb pdb:3L5X|rcsb pdb:3LB6|rcsb pdb:4I77|rcsb pdb:4PS4|rcsb pdb:5E4E|rcsb pdb:5L6Y|reactome:R-HSA-6785807|reactome:R-HSA-9012546	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/06	2017/08/10	rogid:LItbTlLuFXGhjC4PVCIW9aeBRZk9606	rogid:NORPxfYHTfYxQaFWP3FFlC76bWE9606	rigid:wPMlTdJsawR38ioaYml0+k5Ti7c	false	binding-associated region:29-331	binding-associated region:21-132	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P78552	uniprotkb:P35225	intact:EBI-1391535|uniprotkb:O95646|uniprotkb:Q99656|intact:EBI-3918927|uniprotkb:Q5JSL4|uniprotkb:Q9UDY5|ensembl:ENSP00000360730	intact:EBI-1647828|uniprotkb:O43644|uniprotkb:Q4VB52|uniprotkb:Q9UDC7|ensembl:ENSP00000304915	psi-mi:i13r1_human(display_long)|uniprotkb:Cancer/testis antigen 19(gene name synonym)|uniprotkb:IL13RA1(gene name)|psi-mi:IL13RA1(display_short)|uniprotkb:IL13R(gene name synonym)|uniprotkb:IL13RA(gene name synonym)	psi-mi:il13_human(display_long)|uniprotkb:IL13(gene name)|psi-mi:IL13(display_short)|uniprotkb:NC30(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Lupardus et al. (2010)	pubmed:20223216|doi:10.1016/j.str.2010.01.003|imex:IM-15909	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15842014|imex:IM-15909-6|dip:DIP-4497E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001551.1|dip:DIP-3225N|ensembl:ENSG00000131724(gene)|interpro:IPR036116|interpro:IPR040566|rcsb pdb:3BPN|ensembl:ENST00000371666(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005898"(interleukin-13 receptor complex)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0043235"(receptor complex)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|rcsb pdb:3BPO|rcsb pdb:4HWB|rcsb pdb:5E4E|reactome:R-HSA-6785807	refseq:NP_002179.2|dip:DIP-3224N|ensembl:ENSG00000169194(gene)|ensembl:ENST00000304506(transcript)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005144"(interleukin-13 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010155"(regulation of proton transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032723"(positive regulation of connective tissue growth factor production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0035094"(response to nicotine)|go:"GO:0042116"(macrophage activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0045471"(response to ethanol)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901247"(negative regulation of lung ciliated cell differentiation)|go:"GO:1901251"(positive regulation of lung goblet cell differentiation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:2000231"(positive regulation of pancreatic stellate cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR001325(Interleukin-4/interleukin-13)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR018096|interpro:IPR020470|rcsb pdb:1GA3|rcsb pdb:1IJZ|rcsb pdb:1IK0|rcsb pdb:1J9U|rcsb pdb:3BPO|rcsb pdb:3G6D|rcsb pdb:3ITR|rcsb pdb:3ITS|rcsb pdb:3L5W|rcsb pdb:3L5X|rcsb pdb:3LB6|rcsb pdb:4I77|rcsb pdb:4PS4|rcsb pdb:5E4E|rcsb pdb:5L6Y|reactome:R-HSA-6785807|reactome:R-HSA-9012546	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:EufIBLLPq2hkBrfc1evg9tTfp1o9606	rogid:NORPxfYHTfYxQaFWP3FFlC76bWE9606	rigid:Z1zIbPxztQp3LG7UOVwxlKhUFMk	false	-	binding-associated region:21-132|mutation decreasing interaction:47-47|mutation decreasing interaction:137-137|mutation decreasing interaction:140-140|mutation decreasing interaction:123-123|mutation decreasing interaction:124-124|mutation decreasing interaction:122-122|mutation decreasing interaction:66-66|mutation decreasing interaction:141-141	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)