#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00491	uniprotkb:P00491	intact:EBI-712238|ensembl:ENSP00000354532|uniprotkb:Q15160|uniprotkb:Q5PZ03|uniprotkb:B2R8S5|uniprotkb:D3DS00	intact:EBI-712238|ensembl:ENSP00000354532|uniprotkb:Q15160|uniprotkb:Q5PZ03|uniprotkb:B2R8S5|uniprotkb:D3DS00	psi-mi:pnph_human(display_long)|uniprotkb:Inosine phosphorylase(gene name synonym)|uniprotkb:PNP(gene name)|psi-mi:PNP(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Inosine-guanosine phosphorylase(gene name synonym)	psi-mi:pnph_human(display_long)|uniprotkb:Inosine phosphorylase(gene name synonym)|uniprotkb:PNP(gene name)|psi-mi:PNP(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Inosine-guanosine phosphorylase(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ho et al. (2010)	pubmed:20212140|doi:10.1073/pnas.0913439107|imex:IM-15232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15840613|imex:IM-15232-1|dip:DIP-185726E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001882"(nucleoside binding)|go:"GO:0002060"(purine nucleobase binding)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006148"(inosine catabolic process)|go:"GO:0006149"(deoxyinosine catabolic process)|go:"GO:0006157"(deoxyadenosine catabolic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0006738"(nicotinamide riboside catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043101"(purine-containing compound salvage)|go:"GO:0046059"(dAMP catabolic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR011268(Inosine guanosine and xanthosine phosphorylase)|interpro:IPR011270(Purine nucleoside phosphorylase I, inosine and guanosine-specific)|interpro:IPR018099|interpro:IPR035994|mint:P00491|rcsb pdb:1M73|rcsb pdb:1PF7|rcsb pdb:1PWY|rcsb pdb:1RCT|rcsb pdb:1RFG|rcsb pdb:1RR6|rcsb pdb:1RSZ|rcsb pdb:1RT9|rcsb pdb:1ULA|rcsb pdb:1ULB|rcsb pdb:1V2H|rcsb pdb:1V3Q|rcsb pdb:1V41|rcsb pdb:1V45|rcsb pdb:1YRY|rcsb pdb:2A0W|rcsb pdb:2A0X|rcsb pdb:2A0Y|rcsb pdb:2OC4|rcsb pdb:2OC9|rcsb pdb:2ON6|rcsb pdb:2Q7O|rcsb pdb:3BGS|rcsb pdb:3D1V|rcsb pdb:3GB9|rcsb pdb:3GGS|ensembl:ENSG00000198805(gene)|ensembl:ENST00000361505(transcript)|go:"GO:0000255"(allantoin metabolic process)|rcsb pdb:3K8O|rcsb pdb:3K8Q|rcsb pdb:3PHB|rcsb pdb:4EAR|rcsb pdb:3INY|rcsb pdb:4EB8|rcsb pdb:4ECE|rcsb pdb:4GKA|rcsb pdb:5ETJ|rcsb pdb:5UGF|reactome:R-HSA-6798695|reactome:R-HSA-74217|reactome:R-HSA-74259|refseq:NP_000261.2|dip:DIP-50406N	go:"GO:0001882"(nucleoside binding)|go:"GO:0002060"(purine nucleobase binding)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006148"(inosine catabolic process)|go:"GO:0006149"(deoxyinosine catabolic process)|go:"GO:0006157"(deoxyadenosine catabolic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0006738"(nicotinamide riboside catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043101"(purine-containing compound salvage)|go:"GO:0046059"(dAMP catabolic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR011268(Inosine guanosine and xanthosine phosphorylase)|interpro:IPR011270(Purine nucleoside phosphorylase I, inosine and guanosine-specific)|interpro:IPR018099|interpro:IPR035994|mint:P00491|rcsb pdb:1M73|rcsb pdb:1PF7|rcsb pdb:1PWY|rcsb pdb:1RCT|rcsb pdb:1RFG|rcsb pdb:1RR6|rcsb pdb:1RSZ|rcsb pdb:1RT9|rcsb pdb:1ULA|rcsb pdb:1ULB|rcsb pdb:1V2H|rcsb pdb:1V3Q|rcsb pdb:1V41|rcsb pdb:1V45|rcsb pdb:1YRY|rcsb pdb:2A0W|rcsb pdb:2A0X|rcsb pdb:2A0Y|rcsb pdb:2OC4|rcsb pdb:2OC9|rcsb pdb:2ON6|rcsb pdb:2Q7O|rcsb pdb:3BGS|rcsb pdb:3D1V|rcsb pdb:3GB9|rcsb pdb:3GGS|ensembl:ENSG00000198805(gene)|ensembl:ENST00000361505(transcript)|go:"GO:0000255"(allantoin metabolic process)|rcsb pdb:3K8O|rcsb pdb:3K8Q|rcsb pdb:3PHB|rcsb pdb:4EAR|rcsb pdb:3INY|rcsb pdb:4EB8|rcsb pdb:4ECE|rcsb pdb:4GKA|rcsb pdb:5ETJ|rcsb pdb:5UGF|reactome:R-HSA-6798695|reactome:R-HSA-74217|reactome:R-HSA-74259|refseq:NP_000261.2|dip:DIP-50406N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:FOpaxV/M6HIA+THugPZDfN1ej1o9606	rogid:FOpaxV/M6HIA+THugPZDfN1ej1o9606	rigid:vaxT6MoXkiTch3Ar/6fa7SbZBUk	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)