#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P25045	uniprotkb:P53224	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:"MI:0096"(pull down)	Han et al. (2010)	pubmed:20212121|doi:10.1073/pnas.0911617107|imex:IM-15238	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15840536|imex:IM-15238-1|dip:DIP-103488E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	psi-mi:"MI:0465"(dip)	crc64:9F7F93E4B2C70FDB	crc64:4387D00ACE4F3A1D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rigid:LJURNlumFTdFQIPsBpJeCC15y/g	false	ha tag:n-n	tandem tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06144	uniprotkb:P25045	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Han et al. (2010)	pubmed:20212121|doi:10.1073/pnas.0911617107|imex:IM-15238	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15840557|imex:IM-15238-2|dip:DIP-103489E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:9F7F93E4B2C70FDB	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rigid:EAqNBXGr5BCWNLMDRwO5Y4NEfeo	false	tandem tag:c-c	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q06144	uniprotkb:P40970	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-10067|uniprotkb:Q66RG8|uniprotkb:D6VS48|ensemblfungi:YDR062W	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:lcb2_yeast(display_long)|uniprotkb:LCB2(gene name)|psi-mi:LCB2(display_short)|uniprotkb:SCS1(gene name synonym)|uniprotkb:YDR062W(locus name)|uniprotkb:YD9609.16(orf name)|uniprotkb:D4246(orf name)|uniprotkb:TSC1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Han et al. (2010)	pubmed:20212121|doi:10.1073/pnas.0911617107|imex:IM-15238	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15840578|imex:IM-15238-3|dip:DIP-185737E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	refseq:NP_010347.1|sgd:S000002469|ensemblfungi:YDR062W_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YDR062W(gene)|dip:DIP-6658N	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:06DF4A709CC9F29B	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:9HWPnbYvkOQbNXB583l8v3dkiz8559292	rigid:lrd7+IvF+0CDwmGmKmMz1Vdq1LY	false	tandem tag:c-c	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06144	uniprotkb:P25045	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Han et al. (2010)	pubmed:20212121|doi:10.1073/pnas.0911617107|imex:IM-15238	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15840578|imex:IM-15238-3|dip:DIP-185737E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:9F7F93E4B2C70FDB	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rigid:lrd7+IvF+0CDwmGmKmMz1Vdq1LY	false	tandem tag:c-c	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)