#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P53224	uniprotkb:Q3E790	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	intact:EBI-2097198|uniprotkb:D6VQ58|ensemblfungi:YBR058C-A	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:tsc3_yeast(display_long)|uniprotkb:TSC3(gene name)|psi-mi:TSC3(display_short)|uniprotkb:Temperature-sensitive CSG2-mutant suppressor protein 3(gene name synonym)|uniprotkb:YBR058C-A(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838797|imex:IM-14561-1|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	sgd:S000007521|refseq:NP_116327.3|dip:DIP-47347N|ensemblfungi:YBR058C-A(gene)|ensemblfungi:YBR058C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006666"(3-keto-sphinganine metabolic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090154"(positive regulation of sphingolipid biosynthetic process)	psi-mi:"MI:0465"(dip)	crc64:4387D00ACE4F3A1D	crc64:F23EE19603FEC87E	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rogid:RS7OZG+yOS2PFbpRdmYX2g8sjuw559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P53224	uniprotkb:P40970	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	intact:EBI-10067|uniprotkb:Q66RG8|uniprotkb:D6VS48|ensemblfungi:YDR062W	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:lcb2_yeast(display_long)|uniprotkb:LCB2(gene name)|psi-mi:LCB2(display_short)|uniprotkb:SCS1(gene name synonym)|uniprotkb:YDR062W(locus name)|uniprotkb:YD9609.16(orf name)|uniprotkb:D4246(orf name)|uniprotkb:TSC1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838797|imex:IM-14561-1|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	refseq:NP_010347.1|sgd:S000002469|ensemblfungi:YDR062W_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YDR062W(gene)|dip:DIP-6658N	psi-mi:"MI:0465"(dip)	crc64:4387D00ACE4F3A1D	crc64:06DF4A709CC9F29B	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rogid:9HWPnbYvkOQbNXB583l8v3dkiz8559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P53224	uniprotkb:P25045	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838797|imex:IM-14561-1|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	psi-mi:"MI:0465"(dip)	crc64:4387D00ACE4F3A1D	crc64:9F7F93E4B2C70FDB	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P53224	uniprotkb:P32368	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	intact:EBI-16210|ensemblfungi:YKL212W|uniprotkb:D6VWZ1	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:sac1_yeast(display_long)|uniprotkb:SAC1(gene name)|psi-mi:SAC1(display_short)|uniprotkb:RSD1(gene name synonym)|uniprotkb:YKL212W(locus name)|uniprotkb:Recessive suppressor of secretory defect(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838797|imex:IM-14561-1|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	ensemblfungi:YKL212W(gene)|ensemblfungi:YKL212W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0035339"(SPOTS complex)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0072517"(host cell viral assembly compartment)|interpro:IPR002013(Synaptojanin, N-terminal)|rcsb pdb:3LWT|rcsb pdb:4TU3|reactome:R-SCE-1483248|reactome:R-SCE-1660514|reactome:R-SCE-1660516|refseq:NP_012710.1|sgd:S000001695|dip:DIP-6610N|mint:P32368	psi-mi:"MI:0465"(dip)	crc64:4387D00ACE4F3A1D	crc64:73DB1FA163BC17AE	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rogid:MjUsiA11tbe6dHMnFscX13x3gCM559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P53224	uniprotkb:Q06144	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838797|imex:IM-14561-1|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	psi-mi:"MI:0465"(dip)	crc64:4387D00ACE4F3A1D	crc64:2F474503CAB7C195	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q06144	uniprotkb:Q3E790	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-2097198|uniprotkb:D6VQ58|ensemblfungi:YBR058C-A	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:tsc3_yeast(display_long)|uniprotkb:TSC3(gene name)|psi-mi:TSC3(display_short)|uniprotkb:Temperature-sensitive CSG2-mutant suppressor protein 3(gene name synonym)|uniprotkb:YBR058C-A(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838820|imex:IM-14561-2|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	sgd:S000007521|refseq:NP_116327.3|dip:DIP-47347N|ensemblfungi:YBR058C-A(gene)|ensemblfungi:YBR058C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006666"(3-keto-sphinganine metabolic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090154"(positive regulation of sphingolipid biosynthetic process)	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:F23EE19603FEC87E	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:RS7OZG+yOS2PFbpRdmYX2g8sjuw559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q06144	uniprotkb:P40970	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-10067|uniprotkb:Q66RG8|uniprotkb:D6VS48|ensemblfungi:YDR062W	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:lcb2_yeast(display_long)|uniprotkb:LCB2(gene name)|psi-mi:LCB2(display_short)|uniprotkb:SCS1(gene name synonym)|uniprotkb:YDR062W(locus name)|uniprotkb:YD9609.16(orf name)|uniprotkb:D4246(orf name)|uniprotkb:TSC1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838820|imex:IM-14561-2|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	refseq:NP_010347.1|sgd:S000002469|ensemblfungi:YDR062W_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YDR062W(gene)|dip:DIP-6658N	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:06DF4A709CC9F29B	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:9HWPnbYvkOQbNXB583l8v3dkiz8559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q06144	uniprotkb:P25045	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838820|imex:IM-14561-2|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:9F7F93E4B2C70FDB	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q06144	uniprotkb:P32368	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-16210|ensemblfungi:YKL212W|uniprotkb:D6VWZ1	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:sac1_yeast(display_long)|uniprotkb:SAC1(gene name)|psi-mi:SAC1(display_short)|uniprotkb:RSD1(gene name synonym)|uniprotkb:YKL212W(locus name)|uniprotkb:Recessive suppressor of secretory defect(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838820|imex:IM-14561-2|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	ensemblfungi:YKL212W(gene)|ensemblfungi:YKL212W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0035339"(SPOTS complex)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0072517"(host cell viral assembly compartment)|interpro:IPR002013(Synaptojanin, N-terminal)|rcsb pdb:3LWT|rcsb pdb:4TU3|reactome:R-SCE-1483248|reactome:R-SCE-1660514|reactome:R-SCE-1660516|refseq:NP_012710.1|sgd:S000001695|dip:DIP-6610N|mint:P32368	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:73DB1FA163BC17AE	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:MjUsiA11tbe6dHMnFscX13x3gCM559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q06144	uniprotkb:P53224	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838820|imex:IM-14561-2|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:4387D00ACE4F3A1D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q06144	uniprotkb:P25045	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838843|imex:IM-14561-3|dip:DIP-103487E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:9F7F93E4B2C70FDB	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rigid:Xqwc9pGHso8tYdWt+lme6CXYEGg	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q06144	uniprotkb:P53224	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838843|imex:IM-14561-3|dip:DIP-103487E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:4387D00ACE4F3A1D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rigid:Xqwc9pGHso8tYdWt+lme6CXYEGg	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25045	uniprotkb:Q06144	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838865|imex:IM-14561-4|dip:DIP-103489E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	psi-mi:"MI:0465"(dip)	crc64:9F7F93E4B2C70FDB	crc64:2F474503CAB7C195	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rigid:EAqNBXGr5BCWNLMDRwO5Y4NEfeo	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53224	uniprotkb:P25045	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838884|imex:IM-14561-5|dip:DIP-103488E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	psi-mi:"MI:0465"(dip)	crc64:4387D00ACE4F3A1D	crc64:9F7F93E4B2C70FDB	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rigid:LJURNlumFTdFQIPsBpJeCC15y/g	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53224	uniprotkb:P53224	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838884|imex:IM-14561-5|dip:DIP-103488E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	psi-mi:"MI:0465"(dip)	crc64:4387D00ACE4F3A1D	crc64:4387D00ACE4F3A1D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/06	2017/08/10	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rigid:LJURNlumFTdFQIPsBpJeCC15y/g	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15269	uniprotkb:Q8N138	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	intact:EBI-721750|uniprotkb:Q6UY83|uniprotkb:B3KS83|ensembl:ENSP00000304858|ensembl:ENSP00000377724|ensembl:ENSP00000464693	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:orml3_human(display_long)|uniprotkb:ORMDL3(gene name)|psi-mi:ORMDL3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838906|imex:IM-14561-6|dip:DIP-103486E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	refseq:NP_644809.1|refseq:NP_001307730.1|refseq:NP_001307731.1|refseq:NP_001307732.1|dip:DIP-48687N|refseq:XP_016880835.1|refseq:XP_016880836.1|refseq:XP_016880837.1|ensembl:ENSG00000172057(gene)|ensembl:ENST00000304046(transcript)|ensembl:ENST00000394169(transcript)|ensembl:ENST00000579695(transcript)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042552"(myelination)|go:"GO:0061744"(motor behavior)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904221"(negative regulation of serine C-palmitoyltransferase activity)|interpro:IPR007203(ORMDL)|interpro:IPR029883|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|reactome:R-HSA-6798695	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rogid:IDP6RMSMs7gmCCqbD9TvidUxFew9606	rigid:C59DyRhvzQfAE1f2T9Jj11C0jHQ	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15269	uniprotkb:Q8N138	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	intact:EBI-721750|uniprotkb:Q6UY83|uniprotkb:B3KS83|ensembl:ENSP00000304858|ensembl:ENSP00000377724|ensembl:ENSP00000464693	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:orml3_human(display_long)|uniprotkb:ORMDL3(gene name)|psi-mi:ORMDL3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838925|imex:IM-14561-7|dip:DIP-103486E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	refseq:NP_644809.1|refseq:NP_001307730.1|refseq:NP_001307731.1|refseq:NP_001307732.1|dip:DIP-48687N|refseq:XP_016880835.1|refseq:XP_016880836.1|refseq:XP_016880837.1|ensembl:ENSG00000172057(gene)|ensembl:ENST00000304046(transcript)|ensembl:ENST00000394169(transcript)|ensembl:ENST00000579695(transcript)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042552"(myelination)|go:"GO:0061744"(motor behavior)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904221"(negative regulation of serine C-palmitoyltransferase activity)|interpro:IPR007203(ORMDL)|interpro:IPR029883|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|reactome:R-HSA-6798695	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rogid:IDP6RMSMs7gmCCqbD9TvidUxFew9606	rigid:C59DyRhvzQfAE1f2T9Jj11C0jHQ	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53224	uniprotkb:P25045	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838967|imex:IM-14561-9|dip:DIP-103487E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	psi-mi:"MI:0465"(dip)	crc64:4387D00ACE4F3A1D	crc64:9F7F93E4B2C70FDB	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rigid:Xqwc9pGHso8tYdWt+lme6CXYEGg	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53224	uniprotkb:Q06144	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838967|imex:IM-14561-9|dip:DIP-103487E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	psi-mi:"MI:0465"(dip)	crc64:4387D00ACE4F3A1D	crc64:2F474503CAB7C195	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rigid:Xqwc9pGHso8tYdWt+lme6CXYEGg	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25045	uniprotkb:Q3E790	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	intact:EBI-2097198|uniprotkb:D6VQ58|ensemblfungi:YBR058C-A	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:tsc3_yeast(display_long)|uniprotkb:TSC3(gene name)|psi-mi:TSC3(display_short)|uniprotkb:Temperature-sensitive CSG2-mutant suppressor protein 3(gene name synonym)|uniprotkb:YBR058C-A(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838944|imex:IM-14561-8|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	sgd:S000007521|refseq:NP_116327.3|dip:DIP-47347N|ensemblfungi:YBR058C-A(gene)|ensemblfungi:YBR058C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006666"(3-keto-sphinganine metabolic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090154"(positive regulation of sphingolipid biosynthetic process)	psi-mi:"MI:0465"(dip)	crc64:9F7F93E4B2C70FDB	crc64:F23EE19603FEC87E	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rogid:RS7OZG+yOS2PFbpRdmYX2g8sjuw559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P25045	uniprotkb:P40970	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	intact:EBI-10067|uniprotkb:Q66RG8|uniprotkb:D6VS48|ensemblfungi:YDR062W	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:lcb2_yeast(display_long)|uniprotkb:LCB2(gene name)|psi-mi:LCB2(display_short)|uniprotkb:SCS1(gene name synonym)|uniprotkb:YDR062W(locus name)|uniprotkb:YD9609.16(orf name)|uniprotkb:D4246(orf name)|uniprotkb:TSC1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838944|imex:IM-14561-8|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	refseq:NP_010347.1|sgd:S000002469|ensemblfungi:YDR062W_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YDR062W(gene)|dip:DIP-6658N	psi-mi:"MI:0465"(dip)	crc64:9F7F93E4B2C70FDB	crc64:06DF4A709CC9F29B	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rogid:9HWPnbYvkOQbNXB583l8v3dkiz8559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P25045	uniprotkb:P32368	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	intact:EBI-16210|ensemblfungi:YKL212W|uniprotkb:D6VWZ1	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:sac1_yeast(display_long)|uniprotkb:SAC1(gene name)|psi-mi:SAC1(display_short)|uniprotkb:RSD1(gene name synonym)|uniprotkb:YKL212W(locus name)|uniprotkb:Recessive suppressor of secretory defect(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838944|imex:IM-14561-8|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	ensemblfungi:YKL212W(gene)|ensemblfungi:YKL212W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0035339"(SPOTS complex)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0072517"(host cell viral assembly compartment)|interpro:IPR002013(Synaptojanin, N-terminal)|rcsb pdb:3LWT|rcsb pdb:4TU3|reactome:R-SCE-1483248|reactome:R-SCE-1660514|reactome:R-SCE-1660516|refseq:NP_012710.1|sgd:S000001695|dip:DIP-6610N|mint:P32368	psi-mi:"MI:0465"(dip)	crc64:9F7F93E4B2C70FDB	crc64:73DB1FA163BC17AE	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rogid:MjUsiA11tbe6dHMnFscX13x3gCM559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P25045	uniprotkb:Q06144	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838944|imex:IM-14561-8|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	psi-mi:"MI:0465"(dip)	crc64:9F7F93E4B2C70FDB	crc64:2F474503CAB7C195	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P25045	uniprotkb:P53224	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838944|imex:IM-14561-8|dip:DIP-103485E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N	psi-mi:"MI:0465"(dip)	crc64:9F7F93E4B2C70FDB	crc64:4387D00ACE4F3A1D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292	rigid:JpW4k5QKrH2tq2QoSax+ex6cE44	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q06144	uniprotkb:Q06144	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838989|imex:IM-14561-10|dip:DIP-103489E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:2F474503CAB7C195	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rigid:EAqNBXGr5BCWNLMDRwO5Y4NEfeo	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06144	uniprotkb:P25045	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Breslow et al. (2010)	pubmed:20182505|doi:10.1038/nature08787|imex:IM-14561	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15838989|imex:IM-14561-10|dip:DIP-103489E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045	psi-mi:"MI:0465"(dip)	crc64:2F474503CAB7C195	crc64:9F7F93E4B2C70FDB	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292	rigid:EAqNBXGr5BCWNLMDRwO5Y4NEfeo	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)