#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62820-1 uniprotkb:P50395 intact:EBI-15666813|ensembl:ENSP00000387286|ensembl:ENSP00000497078|uniprotkb:P11476-1 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:p62820-1(display_long)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)|uniprotkb:YPT1-related protein(gene name synonym) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0096"(pull down) Zhu et al. (2010) pubmed:20176951|doi:10.1073/pnas.0914231107|imex:IM-15225 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15838657|imex:IM-15225-1|dip:DIP-185708E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138069(gene)|ensembl:ENST00000409784(transcript)|ensembl:ENST00000649427(transcript)|intact:EBI-716845(isoform-parent) ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:16+7P1RQERA/UEF0TYmVQAWWXtE false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62820-1 uniprotkb:P50395 intact:EBI-15666813|ensembl:ENSP00000387286|ensembl:ENSP00000497078|uniprotkb:P11476-1 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:p62820-1(display_long)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)|uniprotkb:YPT1-related protein(gene name synonym) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0096"(pull down) Zhu et al. (2010) pubmed:20176951|doi:10.1073/pnas.0914231107|imex:IM-15225 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15838724|imex:IM-15225-3|dip:DIP-185708E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138069(gene)|ensembl:ENST00000409784(transcript)|ensembl:ENST00000649427(transcript)|intact:EBI-716845(isoform-parent) ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:16+7P1RQERA/UEF0TYmVQAWWXtE false his tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62820-1 uniprotkb:Q29ST3 intact:EBI-15666813|ensembl:ENSP00000387286|ensembl:ENSP00000497078|uniprotkb:P11476-1 intact:EBI-15838677 psi-mi:p62820-1(display_long)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)|uniprotkb:YPT1-related protein(gene name synonym) psi-mi:drra_legpn(display_long)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:sidM(gene name synonym)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym) psi-mi:"MI:0096"(pull down) Zhu et al. (2010) pubmed:20176951|doi:10.1073/pnas.0914231107|imex:IM-15225 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:446(legpn)|taxid:446(Legionella pneumophila) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15838745|imex:IM-15225-4|dip:DIP-185707E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138069(gene)|ensembl:ENST00000409784(transcript)|ensembl:ENST00000649427(transcript)|intact:EBI-716845(isoform-parent) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016020"(membrane)|go:"GO:0018117"(protein adenylylation)|go:"GO:0018260"(protein guanylylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044161"(host cell cytoplasmic vesicle)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044600"(protein guanylyltransferase activity)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070733"(protein adenylyltransferase activity)|interpro:IPR028057|interpro:IPR033784|interpro:IPR038346|rcsb pdb:3NKU|rcsb pdb:5O74|rcsb pdb:6YX5|refseq:WP_010948166.1|dip:DIP-58604N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606 rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE446 rigid:8Vz+PnWsGC82SRdNSOQPosZ0qzE false - glutathione s tranferase tag:n-n|binding-associated region:193-550 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P62820-1 uniprotkb:Q29ST3 intact:EBI-15666813|ensembl:ENSP00000387286|ensembl:ENSP00000497078|uniprotkb:P11476-1 intact:EBI-15838677 psi-mi:p62820-1(display_long)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)|uniprotkb:YPT1-related protein(gene name synonym) psi-mi:drra_legpn(display_long)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:sidM(gene name synonym)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zhu et al. (2010) pubmed:20176951|doi:10.1073/pnas.0914231107|imex:IM-15225 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:446(legpn)|taxid:446(Legionella pneumophila) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15838703|imex:IM-15225-2|dip:DIP-185707E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138069(gene)|ensembl:ENST00000409784(transcript)|ensembl:ENST00000649427(transcript)|intact:EBI-716845(isoform-parent) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016020"(membrane)|go:"GO:0018117"(protein adenylylation)|go:"GO:0018260"(protein guanylylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044161"(host cell cytoplasmic vesicle)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044600"(protein guanylyltransferase activity)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070733"(protein adenylyltransferase activity)|interpro:IPR028057|interpro:IPR033784|interpro:IPR038346|rcsb pdb:3NKU|rcsb pdb:5O74|rcsb pdb:6YX5|refseq:WP_010948166.1|dip:DIP-58604N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606 rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE446 rigid:8Vz+PnWsGC82SRdNSOQPosZ0qzE false binding-associated region:1-177 binding-associated region:193-550 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62820-1 uniprotkb:Q29ST3 intact:EBI-15666813|ensembl:ENSP00000387286|ensembl:ENSP00000497078|uniprotkb:P11476-1 intact:EBI-15838677 psi-mi:p62820-1(display_long)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)|uniprotkb:YPT1-related protein(gene name synonym) psi-mi:drra_legpn(display_long)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:sidM(gene name synonym)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Zhu et al. (2010) pubmed:20176951|doi:10.1073/pnas.0914231107|imex:IM-15225 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:446(legpn)|taxid:446(Legionella pneumophila) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15838766|imex:IM-15225-5|dip:DIP-185707E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138069(gene)|ensembl:ENST00000409784(transcript)|ensembl:ENST00000649427(transcript)|intact:EBI-716845(isoform-parent) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016020"(membrane)|go:"GO:0018117"(protein adenylylation)|go:"GO:0018260"(protein guanylylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044161"(host cell cytoplasmic vesicle)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044600"(protein guanylyltransferase activity)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070733"(protein adenylyltransferase activity)|interpro:IPR028057|interpro:IPR033784|interpro:IPR038346|rcsb pdb:3NKU|rcsb pdb:5O74|rcsb pdb:6YX5|refseq:WP_010948166.1|dip:DIP-58604N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606 rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE446 rigid:8Vz+PnWsGC82SRdNSOQPosZ0qzE false binding-associated region:1-177 binding-associated region:193-550 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)