#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P47050	uniprotkb:Q06164	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186410|imex:IM-25794-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:A86A48F6DC6AF163	crc64:EE9797D4A12A7488	figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P47050	uniprotkb:Q06211	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186410|imex:IM-25794-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:A86A48F6DC6AF163	crc64:CC698C422631A7D7	figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P47050	uniprotkb:Q06164	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186428|imex:IM-25794-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:A86A48F6DC6AF163	crc64:EE9797D4A12A7488	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	myc tag:?-?	his tag:?-?|ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47050	uniprotkb:Q06211	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186428|imex:IM-25794-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:A86A48F6DC6AF163	crc64:CC698C422631A7D7	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06211	uniprotkb:P47050	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186455|imex:IM-25794-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:CC698C422631A7D7	crc64:A86A48F6DC6AF163	figure legend:Fig. 1B, 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:yoWEjB+Jcgvdfv0a/iJMefXgtt0	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06211	uniprotkb:Q06164	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186464|imex:IM-25794-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:CC698C422631A7D7	crc64:EE9797D4A12A7488	figure legend:Fig. 1B, 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	flag tag:?-?	his tag:?-?|ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06211	uniprotkb:P47050	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186464|imex:IM-25794-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:CC698C422631A7D7	crc64:A86A48F6DC6AF163	figure legend:Fig. 1B, 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06211	uniprotkb:P47050	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186490|imex:IM-25794-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:CC698C422631A7D7	crc64:A86A48F6DC6AF163	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:yoWEjB+Jcgvdfv0a/iJMefXgtt0	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:Q06211	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186499|imex:IM-25794-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:EE9797D4A12A7488	crc64:CC698C422631A7D7	figure legend:Fig. 1B, 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:XxIIHe4i8tlEXEvGssMlgAUVo98	false	his tag:?-?|ha tag:?-?	flag tag:?-?|necessary binding region:1-600	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:Q06211	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186510|imex:IM-25794-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:EE9797D4A12A7488	crc64:CC698C422631A7D7	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	his tag:?-?|ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:P47050	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186510|imex:IM-25794-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:EE9797D4A12A7488	crc64:A86A48F6DC6AF163	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	his tag:?-?|ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:Q06211	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186524|imex:IM-25794-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:EE9797D4A12A7488	crc64:CC698C422631A7D7	figure legend:Fig. 1B, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:XxIIHe4i8tlEXEvGssMlgAUVo98	false	his tag:?-?|ha tag:?-?|necessary binding region:1201-1454	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47050	uniprotkb:Q06164	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186596|imex:IM-25794-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:A86A48F6DC6AF163	crc64:EE9797D4A12A7488	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	myc tag:?-?	his tag:?-?|ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47050	uniprotkb:P38850	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186596|imex:IM-25794-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	-	crc64:A86A48F6DC6AF163	crc64:767931285BB52580	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	myc tag:?-?	tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47050	uniprotkb:Q06211	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186596|imex:IM-25794-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:A86A48F6DC6AF163	crc64:CC698C422631A7D7	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38850	uniprotkb:Q06164	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186613|imex:IM-25794-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:767931285BB52580	crc64:EE9797D4A12A7488	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	tag:?-?	his tag:?-?|ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38850	uniprotkb:Q06211	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186613|imex:IM-25794-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:767931285BB52580	crc64:CC698C422631A7D7	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38850	uniprotkb:P47050	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186613|imex:IM-25794-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:767931285BB52580	crc64:A86A48F6DC6AF163	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:P38850	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186630|imex:IM-25794-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	-	crc64:EE9797D4A12A7488	crc64:767931285BB52580	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rigid:2/0qFxF4P/BuzGnA8FOcPnjWG1s	false	his tag:?-?|ha tag:?-?	tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:P38850	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186750|imex:IM-25794-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	-	crc64:EE9797D4A12A7488	crc64:767931285BB52580	figure legend:Fig. 1B, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rigid:2/0qFxF4P/BuzGnA8FOcPnjWG1s	false	his tag:?-?|ha tag:?-?|necessary binding region:1-300	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:Q01454	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186986|imex:IM-25794-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL	-	crc64:EE9797D4A12A7488	crc64:E2ABBB244B5F8B4D	figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292	rigid:HKisaDf8gnuTIjRFzTPiBhuaxdM	false	his tag:?-?|ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:Q06211	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15187235|imex:IM-25794-38	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:EE9797D4A12A7488	crc64:CC698C422631A7D7	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/23	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:xSA9SDlvWQ/ZiFnyv8bDLA51Cz0	false	his tag:?-?|ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:P38850	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15187235|imex:IM-25794-38	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	-	crc64:EE9797D4A12A7488	crc64:767931285BB52580	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/06/22	2017/06/23	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rigid:xSA9SDlvWQ/ZiFnyv8bDLA51Cz0	false	his tag:?-?|ha tag:?-?	tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47050	uniprotkb:Q06164	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186542|imex:IM-25794-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:A86A48F6DC6AF163	crc64:EE9797D4A12A7488	figure legend:Fig. 1C|comment:Interaction not observed in MMS1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	myc tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47050	uniprotkb:Q06211	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186542|imex:IM-25794-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:A86A48F6DC6AF163	crc64:CC698C422631A7D7	figure legend:Fig. 1C|comment:Interaction not observed in MMS1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06211	uniprotkb:Q06164	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186565|imex:IM-25794-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:CC698C422631A7D7	crc64:EE9797D4A12A7488	figure legend:Fig. 1C|comment:Interaction not observed in MMS1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	ha tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06211	uniprotkb:P47050	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186565|imex:IM-25794-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:CC698C422631A7D7	crc64:A86A48F6DC6AF163	figure legend:Fig. 1C|comment:Interaction not observed in MMS1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:Q06211	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186578|imex:IM-25794-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:EE9797D4A12A7488	crc64:CC698C422631A7D7	figure legend:Fig. 1C|comment:Interaction not observed in MMS1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	v5 tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:P47050	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186578|imex:IM-25794-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:EE9797D4A12A7488	crc64:A86A48F6DC6AF163	figure legend:Fig. 1C|comment:Interaction not observed in MMS1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:aA5Z9YnETSQpIKI0nCqIYQP77eY	false	v5 tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47050	uniprotkb:P38850	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186640|imex:IM-25794-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	-	crc64:A86A48F6DC6AF163	crc64:767931285BB52580	figure legend:Fig. 1E, Supp. Fig. 1|comment:Interaction observed in the presence or the absence of DNA damage by MMS|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47050	uniprotkb:Q06164	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186640|imex:IM-25794-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:A86A48F6DC6AF163	crc64:EE9797D4A12A7488	figure legend:Fig. 1E, Supp. Fig. 1|comment:Interaction observed in the presence or the absence of DNA damage by MMS|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	myc tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47050	uniprotkb:Q06211	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186640|imex:IM-25794-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:A86A48F6DC6AF163	crc64:CC698C422631A7D7	figure legend:Fig. 1E, Supp. Fig. 1|comment:Interaction observed in the presence or the absence of DNA damage by MMS|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06211	uniprotkb:P38850	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186664|imex:IM-25794-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	-	crc64:CC698C422631A7D7	crc64:767931285BB52580	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06211	uniprotkb:Q06164	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186664|imex:IM-25794-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:CC698C422631A7D7	crc64:EE9797D4A12A7488	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	ha tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06211	uniprotkb:P47050	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186664|imex:IM-25794-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:CC698C422631A7D7	crc64:A86A48F6DC6AF163	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:P38850	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186701|imex:IM-25794-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	-	crc64:EE9797D4A12A7488	crc64:767931285BB52580	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	v5 tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:Q06211	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186701|imex:IM-25794-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:EE9797D4A12A7488	crc64:CC698C422631A7D7	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	v5 tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06164	uniprotkb:P47050	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186701|imex:IM-25794-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:EE9797D4A12A7488	crc64:A86A48F6DC6AF163	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	v5 tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38850	uniprotkb:Q06164	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186717|imex:IM-25794-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:767931285BB52580	crc64:EE9797D4A12A7488	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	flag tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38850	uniprotkb:Q06211	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186717|imex:IM-25794-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:767931285BB52580	crc64:CC698C422631A7D7	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38850	uniprotkb:P47050	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186717|imex:IM-25794-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:767931285BB52580	crc64:A86A48F6DC6AF163	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:7PyQpTl57ogw/kWWr7ENM4+9n5I	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38850	uniprotkb:P47050	intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186731|imex:IM-25794-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:767931285BB52580	crc64:A86A48F6DC6AF163	figure legend:Fig. 1F|comment:Interaction not observed in MMS1-/- or MMS22-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:2UmSMdOMOhSg+zDVnycC23Mgink	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q01454	uniprotkb:Q06211	intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186850|imex:IM-25794-24	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:E2ABBB244B5F8B4D	crc64:CC698C422631A7D7	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:QTyWrh/9N+PqxNM4GBeO51lIE6Q	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q01454	uniprotkb:P47050	intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186850|imex:IM-25794-24	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:E2ABBB244B5F8B4D	crc64:A86A48F6DC6AF163	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:QTyWrh/9N+PqxNM4GBeO51lIE6Q	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06340	uniprotkb:Q06211	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186887|imex:IM-25794-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:F691FB73ED2FAF15	crc64:CC698C422631A7D7	figure legend:Fig. 3B, 4B|comment:Interaction not observed in MMS1-/- cells, but was seen in MMS22-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:FmIxKNhOaoYkaTMP9vUdMIF0WNQ	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06340	uniprotkb:P47050	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186887|imex:IM-25794-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:F691FB73ED2FAF15	crc64:A86A48F6DC6AF163	figure legend:Fig. 3B, 4B|comment:Interaction not observed in MMS1-/- cells, but was seen in MMS22-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:FmIxKNhOaoYkaTMP9vUdMIF0WNQ	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P50874	uniprotkb:Q06211	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186902|imex:IM-25794-26	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:1FE5DE28AFF6B41C	crc64:CC698C422631A7D7	figure legend:Fig. 3B, 4C|comment:Interaction was observed in MMS22-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:7B0TLsq8E/EOUkmiN7Ud7RL+Fkw	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P50874	uniprotkb:P47050	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186902|imex:IM-25794-26	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:1FE5DE28AFF6B41C	crc64:A86A48F6DC6AF163	figure legend:Fig. 3B, 4C|comment:Interaction was observed in MMS22-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:7B0TLsq8E/EOUkmiN7Ud7RL+Fkw	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06340	uniprotkb:P47050	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186917|imex:IM-25794-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:F691FB73ED2FAF15	crc64:A86A48F6DC6AF163	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/26	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:bQg414t8T9lU+XcN8tUBzmqA10A	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06340	uniprotkb:Q06211	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186927|imex:IM-25794-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:F691FB73ED2FAF15	crc64:CC698C422631A7D7	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/26	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:QREsabnRSPjoOJqWoVU3m5HPHxw	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P50874	uniprotkb:Q06211	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186948|imex:IM-25794-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:1FE5DE28AFF6B41C	crc64:CC698C422631A7D7	figure legend:Fig. 4C|comment:Interaction observed in CUL8-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:5Hrwg/TvG10nMGHy5Eqdp0aT59M	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P50874	uniprotkb:P47050	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186958|imex:IM-25794-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:1FE5DE28AFF6B41C	crc64:A86A48F6DC6AF163	figure legend:Fig. 4C|comment:Interaction observed in MMS1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:GgZCGwIPpVCXeGqkKl2Wmg+Di54	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q01454	uniprotkb:Q06164	intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186978|imex:IM-25794-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:E2ABBB244B5F8B4D	crc64:EE9797D4A12A7488	figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/22	rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:HKisaDf8gnuTIjRFzTPiBhuaxdM	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06340	uniprotkb:Q06211	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15188446|imex:IM-25794-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:F691FB73ED2FAF15	crc64:CC698C422631A7D7	figure legend:Fig. 4B|comment:Interaction observed in CUL8-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/26	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:QREsabnRSPjoOJqWoVU3m5HPHxw	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06340	uniprotkb:P47050	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15188456|imex:IM-25794-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:F691FB73ED2FAF15	crc64:A86A48F6DC6AF163	figure legend:Fig. 4B|comment:Interaction observed in MMS1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/06/22	2017/06/26	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:bQg414t8T9lU+XcN8tUBzmqA10A	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06340	uniprotkb:Q06211	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0727"(lexa b52 complementation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186770|imex:IM-25794-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:F691FB73ED2FAF15	crc64:CC698C422631A7D7	figure legend:Fig. 3, Supp fig 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/06/22	2017/06/22	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:QREsabnRSPjoOJqWoVU3m5HPHxw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50874	uniprotkb:Q06211	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0727"(lexa b52 complementation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186782|imex:IM-25794-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:1FE5DE28AFF6B41C	crc64:CC698C422631A7D7	figure legend:Fig. 3A, Supp fig 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/06/22	2017/06/22	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:5Hrwg/TvG10nMGHy5Eqdp0aT59M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01454	uniprotkb:Q06164	intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0727"(lexa b52 complementation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15186792|imex:IM-25794-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:E2ABBB244B5F8B4D	crc64:EE9797D4A12A7488	figure legend:Fig. 3A, Supp fig 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/06/22	2017/06/22	rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:HKisaDf8gnuTIjRFzTPiBhuaxdM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01454	uniprotkb:Q06164	intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0727"(lexa b52 complementation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15187006|imex:IM-25794-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164	-	crc64:E2ABBB244B5F8B4D	crc64:EE9797D4A12A7488	figure legend:Fig. 5C, 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/06/22	2017/06/22	rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	rigid:HKisaDf8gnuTIjRFzTPiBhuaxdM	false	sufficient binding region:1-454	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06340	uniprotkb:P47050	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0727"(lexa b52 complementation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15187041|imex:IM-25794-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:F691FB73ED2FAF15	crc64:A86A48F6DC6AF163	figure legend:Supp Fig. 2B|comment:Interaction observed in MMS1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/06/22	2017/06/22	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:bQg414t8T9lU+XcN8tUBzmqA10A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50874	uniprotkb:P47050	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0727"(lexa b52 complementation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15187046|imex:IM-25794-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210	-	crc64:1FE5DE28AFF6B41C	crc64:A86A48F6DC6AF163	figure legend:Supp Fig. 2B|comment:Interaction observed in MMS1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/06/22	2017/06/22	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rigid:GgZCGwIPpVCXeGqkKl2Wmg+Di54	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50874	uniprotkb:Q06211	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0727"(lexa b52 complementation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15187051|imex:IM-25794-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:1FE5DE28AFF6B41C	crc64:CC698C422631A7D7	figure legend:Supp Fig. 2|comment:Interaction observed in CUL8-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/06/22	2017/06/22	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:5Hrwg/TvG10nMGHy5Eqdp0aT59M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06340	uniprotkb:Q06211	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0727"(lexa b52 complementation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15187056|imex:IM-25794-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)	-	crc64:F691FB73ED2FAF15	crc64:CC698C422631A7D7	figure legend:Supp Fig. 2|comment:Interaction observed in CUL8-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/06/22	2017/06/22	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	rigid:QREsabnRSPjoOJqWoVU3m5HPHxw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01454	uniprotkb:Q08496	intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym)	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:"MI:0727"(lexa b52 complementation)	Mimura et al. (2010)	pubmed:20139071|imex:IM-25794	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15188616|imex:IM-25794-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047	-	crc64:E2ABBB244B5F8B4D	crc64:98B610994BA2F803	figure legend:Fig.5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/06/22	2017/06/26	rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	rigid:So4QBDmxqe1+l8/HkoKdVkIWX80	false	necessary binding region:234-706	sufficient binding region:1..1-209..209,250..250-732..732	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)