#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P19332 uniprotkb:Q9QVC8 intact:EBI-7080713|uniprotkb:Q63567|uniprotkb:Q63677|uniprotkb:Q9QW06|intact:MINT-1037362 intact:EBI-15833372|ensembl:ENSRNOP00000008737|uniprotkb:A6IM14|uniprotkb:Q8K3U8 psi-mi:tau_rat(display_long)|uniprotkb:Mapt(gene name)|psi-mi:Mapt(display_short)|uniprotkb:Mtapt(gene name synonym)|uniprotkb:Tau(gene name synonym)|uniprotkb:Neurofibrillary tangle protein(gene name synonym)|uniprotkb:Paired helical filament-tau(gene name synonym) psi-mi:fkbp4_rat(display_long)|uniprotkb:Fkbp4(gene name)|psi-mi:Fkbp4(display_short)|uniprotkb:Fkbp52(gene name synonym)|uniprotkb:52 kDa FK506-binding protein(gene name synonym)|uniprotkb:59 kDa immunophilin(gene name synonym)|uniprotkb:FK506-binding protein 4(gene name synonym)|uniprotkb:FKBP59(gene name synonym)|uniprotkb:HSP-binding immunophilin(gene name synonym)|uniprotkb:Immunophilin FKBP52(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chambraud et al. (2010) pubmed:20133804|doi:10.1073/pnas.0914957107|imex:IM-16249 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15833434|imex:IM-16249-1|dip:DIP-187337E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007584"(response to nutrient)|go:"GO:0007613"(memory)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034399"(nuclear periphery)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0044304"(main axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048675"(axon extension)|go:"GO:0050808"(synapse organization)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0051028"(mRNA transport)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097386"(glial cell projection)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1902474"(positive regulation of protein localization to synapse)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR002955(Tau protein)|go:"GO:1901216"(positive regulation of neuron death)|rgd:69329|dip:DIP-41779N|reactome:R-RNO-264870 ensembl:ENSRNOG00000006444(gene)|ensembl:ENSRNOT00000008737(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006463"(steroid hormone receptor complex assembly)|go:"GO:0006825"(copper ion transport)|go:"GO:0007566"(embryo implantation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030850"(prostate gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031503"(protein-containing complex localization)|go:"GO:0032767"(copper-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046661"(male sex differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR031212|mint:Q9QVC8|reactome:R-RNO-3371497|reactome:R-RNO-3371568|reactome:R-RNO-8939211|reactome:R-RNO-9018519|refseq:NP_001178792.1|dip:DIP-59214N|rgd:628729 psi-mi:"MI:0465"(dip) comment:mint|function:"Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization" - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2017/08/06 2017/08/10 rogid:65t+kCG5P0Iv7QNaptNW3GSjsEA10116 rogid:vwtyeDHbJffl3vqLdQN/BTl9v8M10116 rigid:6L4XaF+gyeyMFOkpSKDyVo4XaFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P19332 uniprotkb:Q02790 intact:EBI-7080713|uniprotkb:Q63567|uniprotkb:Q63677|uniprotkb:Q9QW06|intact:MINT-1037362 intact:EBI-1047444|uniprotkb:D3DUQ1|uniprotkb:Q9UCP1|uniprotkb:Q9UCV7|ensembl:ENSP00000001008 psi-mi:tau_rat(display_long)|uniprotkb:Mapt(gene name)|psi-mi:Mapt(display_short)|uniprotkb:Mtapt(gene name synonym)|uniprotkb:Tau(gene name synonym)|uniprotkb:Neurofibrillary tangle protein(gene name synonym)|uniprotkb:Paired helical filament-tau(gene name synonym) psi-mi:fkbp4_human(display_long)|uniprotkb:FK506-binding protein 4(gene name synonym)|uniprotkb:HSP-binding immunophilin(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:52 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBP59(gene name synonym)|uniprotkb:Immunophilin FKBP52(gene name synonym)|uniprotkb:FKBP4(gene name)|psi-mi:FKBP4(display_short)|uniprotkb:FKBP52(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:59 kDa immunophilin(gene name synonym) psi-mi:"MI:0096"(pull down) Chambraud et al. (2010) pubmed:20133804|doi:10.1073/pnas.0914957107|imex:IM-16249 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15833451|imex:IM-16249-2|dip:DIP-187338E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007584"(response to nutrient)|go:"GO:0007613"(memory)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034399"(nuclear periphery)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0044304"(main axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048675"(axon extension)|go:"GO:0050808"(synapse organization)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0051028"(mRNA transport)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097386"(glial cell projection)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1902474"(positive regulation of protein localization to synapse)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR002955(Tau protein)|go:"GO:1901216"(positive regulation of neuron death)|rgd:69329|dip:DIP-41779N|reactome:R-RNO-264870 refseq:NP_002005.1|go:"GO:0070062"(extracellular exosome)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR031212|mint:Q02790|rcsb pdb:1N1A|rcsb pdb:1P5Q|rcsb pdb:1Q1C|rcsb pdb:1QZ2|rcsb pdb:4DRJ|rcsb pdb:4LAV|rcsb pdb:4LAW|rcsb pdb:4LAX|rcsb pdb:4LAY|rcsb pdb:4TW8|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6RCY|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|ensembl:ENST00000001008(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|ensembl:ENSG00000004478(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0006825"(copper ion transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0032767"(copper-dependent protein binding)|dip:DIP-50866N psi-mi:"MI:0465"(dip) comment:mint|function:"Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization" - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:65t+kCG5P0Iv7QNaptNW3GSjsEA10116 rogid:N0vDRDgcQ2x8xiWKdX9Zt+cHcsQ9606 rigid:EQWqb2vGP/HNmyJZPxBOE0/H6cI false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10636-8 uniprotkb:Q02790 intact:EBI-366233|ensembl:ENSP00000303214|ensembl:ENSP00000460965|ensembl:ENSP00000477703|ensembl:ENSP00000484491|ensembl:ENSP00000487819|intact:EBI-7470331|intact:MINT-134477|intact:EBI-7470384|intact:EBI-7638179|intact:EBI-7638125|intact:EBI-7638230|intact:EBI-7638364|intact:EBI-7961077|intact:EBI-7470086|intact:EBI-7637965|intact:EBI-7638329|intact:EBI-7470156|intact:EBI-7470185|intact:EBI-7470243|intact:EBI-7638049|intact:EBI-7470111|intact:EBI-7637861 intact:EBI-1047444|uniprotkb:D3DUQ1|uniprotkb:Q9UCP1|uniprotkb:Q9UCV7|ensembl:ENSP00000001008 psi-mi:p10636-8(display_long)|uniprotkb:Tau-4(isoform synonym)|uniprotkb:MAPT(gene name)|psi-mi:MAPT(display_short)|uniprotkb:MAPTL(gene name synonym)|uniprotkb:MTBT1(gene name synonym)|uniprotkb:TAU(gene name synonym)|uniprotkb:Neurofibrillary tangle protein(gene name synonym)|uniprotkb:Paired helical filament-tau(gene name synonym)|uniprotkb:2N4R(isoform synonym) psi-mi:fkbp4_human(display_long)|uniprotkb:FK506-binding protein 4(gene name synonym)|uniprotkb:HSP-binding immunophilin(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:52 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBP59(gene name synonym)|uniprotkb:Immunophilin FKBP52(gene name synonym)|uniprotkb:FKBP4(gene name)|psi-mi:FKBP4(display_short)|uniprotkb:FKBP52(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:59 kDa immunophilin(gene name synonym) psi-mi:"MI:0047"(far western blotting) Chambraud et al. (2010) pubmed:20133804|doi:10.1073/pnas.0914957107|imex:IM-16249 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15833470|imex:IM-16249-3|dip:DIP-187339E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-366182(tau_human)|ensembl:ENSG00000277956(gene)|ensembl:ENSG00000186868(gene)|ensembl:ENSG00000276155(gene)|ensembl:ENST00000351559(transcript)|ensembl:ENST00000574436(transcript)|ensembl:ENST00000620070(transcript)|ensembl:ENST00000621329(transcript)|ensembl:ENST00000634049(transcript) refseq:NP_002005.1|go:"GO:0070062"(extracellular exosome)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR031212|mint:Q02790|rcsb pdb:1N1A|rcsb pdb:1P5Q|rcsb pdb:1Q1C|rcsb pdb:1QZ2|rcsb pdb:4DRJ|rcsb pdb:4LAV|rcsb pdb:4LAW|rcsb pdb:4LAX|rcsb pdb:4LAY|rcsb pdb:4TW8|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6RCY|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|ensembl:ENST00000001008(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|ensembl:ENSG00000004478(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0006825"(copper ion transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0032767"(copper-dependent protein binding)|dip:DIP-50866N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:S/u8VrnYmDN6stlDTynwCvSaOeo9606 rogid:N0vDRDgcQ2x8xiWKdX9Zt+cHcsQ9606 rigid:UMZkYivOyvCQ9q/pddrONqDER1Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)